Kussmaul Aphasia

The inability to generate oral-verbal expression, despite normal comprehension of speech. This may be associated with BRAIN DISEASES or MENTAL DISORDERS. Organic mutism may be associated with damage to the FRONTAL LOBE; BRAIN STEM; THALAMUS; and CEREBELLUM. Selective mutism is a psychological condition that usually affects children characterized by continuous refusal to speak in social situations by a child who is able and willing to speak to selected persons. Kussmal aphasia refers to mutism in psychosis. (From Fortschr Neurol Psychiatr 1994; 62(9):337-44)

Synonym
Mutism
Kussmaul Aphasia
Mutism, Voluntary
Mutism, Elective
Mutism, Organic
Kussmaul's Aphasia
Mutism, Conversion
Mutism, Selective
Selective Mutism

Excerpt	Reference
"A clinical case of mutism is described in this research to illustrate the usefulness of the amytal interview."	( Lavallée, JC; Tremblay, M, 1992)
"Mutism is a common manifestation of both psychiatric and neurologic illness."	( Altshuler, LL; Cummings, JL; Mills, MJ, 1986)
"Selective mutism is a rare disorder with poor treatment outcome."	( Anderson, JH; Cuccaro, ML; Kendall, DF; Leonhardt, TV; Wright, HH, 1995)
"Mutism is an infrequent and transitory complication observed following posterior fossa surgery."	( Baldari, S; Caffo, M; Cardia, E; Caruso, G; Germanò, A; Montemagno, G; Tomasello, F, 1998)
"Akinetic mutism is a behavioral state wherein a patient seems to be awake but does not move or speak."	( Albayrak, A; Altinörs, N; Benli, S; Calişaneller, T; Caner, H, 1999)
"Selective mutism is a communication disorder of childhood in which the child does not speak in specific social situations despite the ability to speak in other situations."	( Melfsen, S; Warnke, A, 2007)
"Mutism is an uncommon complication of calcineurin inhibitors."	( Greenberg, MI; Simpson, SE; Vearrier, D, 2011)
"Selective mutism is rare with a prevalence below 1% in the general population, but a higher prevalence in populations at risk (children with speech retardation, migration)."	( Gatz, SA; Kölch, M; Ludolph, AG; Plener, PL; Schuetz, C, 2012)

Excerpt	Reference
"Sixteen subjects with elective mutism were treated with placebo (single-blind) for 2 weeks."	( Black, B; Uhde, TW, 1994)
"A 38-year-old woman was treated for mutism with clozapine."	( Hovens, JE; Thunnissen, PL; Verhoeve, HA; Vogtländer, LM, 1994)
"Persistent selective mutism presenting with comorbid anxiety disorders may respond to fluoxetine treatment."	( Asche, B; Dummit, ES; Klein, RG; Martin, J; Tancer, NK, 1996)

Timeframe	Studies, This Condition (%)	All Conditions %
pre-1990	48 (33.10)	23.3326
1990's	35 (24.14)	12.5806
2000's	27 (18.62)	18.1394
2010's	27 (18.62)	28.8240
2020's	8 (5.52)	9.53

Drug	Relationship Strength	Studies	Trials
2,5-dichlorophenol	low	1	0
gamma-aminobutyric acid	low	1	0
adenine	low	1	0
carbon monoxide	low	2	0
glycine	low	1	0
hydrogen carbonate	low	1	0
iodine	low	1	0
dihydroxyphenylalanine	low	1	0
thiamine	low	2	0
uric acid	low	1	0
alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid	low	1	0
phenytoin	low	2	0
acetazolamide	low	1	0
albendazole	low	1	0
alprazolam	low	1	0
amantadine	low	1	0
amobarbital	medium	8	1
aspirin	low	1	0
bromperidol	low	1	0
carbamazepine	low	2	0
carmofur	low	1	0
chlorpromazine	low	2	0
clonidine	low	1	0
desipramine	medium	1	1
diazepam	low	9	0
valproic acid	low	2	0
flumazenil	low	2	0
fluorouracil	low	1	0
fluoxetine	medium	18	3
haloperidol	low	4	0
phenelzine	low	3	0
ifosfamide	low	1	0
imipramine	low	2	0
lorazepam	medium	8	1
mesoridazine	medium	1	1
methadone	low	1	0
methylphenidate	low	2	0
midazolam	low	1	0
apnea	low	1	0
oxazepam	medium	1	1
4-dichlorobenzene	low	1	0
perphenazine	low	1	0
phenobarbital	low	1	0
phenylbutazone	low	1	0
promazine	low	1	0
propofol	low	3	0
risperidone	low	2	0
secobarbital	low	1	0
tegafur	low	1	0
trifluoperazine	low	1	0
zolpidem	low	1	0
zonisamide	low	1	0
prednisolone	low	1	0
prednisone	low	1	0
physostigmine	low	1	0
2,3,4,6-tetrachlorophenol	low	1	0
phenylalanine	low	1	0
histidine	low	1	0
methylprednisolone	low	2	0
xanthenes	low	1	0
isoxazoles	low	1	0
lormetazepam	low	1	0
s,n,n'-tripropylthiocarbamate	medium	9	1
fluorescein	low	1	0
bromocriptine	low	4	0
cetylpyridinium chloride anhydrous	low	1	0
paroxetine	low	2	0
fomesafen	low	3	0
simvastatin	low	1	0
aripiprazole	low	1	0
capecitabine	low	1	0
fluorodeoxyglucose f18	low	2	0
sertraline	medium	3	1
methotrimeprazine	low	1	0
fingolimod hydrochloride	low	1	0
pramipexole	low	1	0
cortisone	low	1	0
inositol 3-phosphate	low	1	0
metrizamide	low	1	0
tacrolimus	low	3	0
benztropine	low	1	0
lithium	low	1	0
quinine	low	1	0
humulene	low	1	0
levetiracetam	low	1	0
morphine	low	1	0
fluvoxamine	medium	3	1
cysteine	low	4	0
everolimus	low	1	0
technetium tc 99m exametazime	low	2	0
sodium ethylxanthate	low	1	0
cyclosporine	low	2	0
guanine	low	1	0
clozapine	low	4	0
allopurinol	low	1	0
ego	low	3	0
technetium tc 99m bicisate	low	4	0

Protein Targets (1,234)

Protein	Potency Measurements	Inhibition Measurements	Activation Measurements	Drugs
Chain A, HADH2 protein	10	0	0	10
Chain B, HADH2 protein	10	0	0	10
Luciferase	12	0	0	12
interleukin 8	4	0	0	4
RAR-related orphan receptor gamma	26	0	0	26
GLI family zinc finger 3	34	0	0	34
AR protein	44	0	0	44
thyroid stimulating hormone receptor	17	0	0	17
estrogen receptor 2 (ER beta)	17	0	0	17
nuclear receptor subfamily 1, group I, member 3	30	0	0	30
progesterone receptor	24	0	0	24
glucocorticoid receptor [Homo sapiens]	36	0	0	36
retinoic acid nuclear receptor alpha variant 1	30	0	0	30
retinoid X nuclear receptor alpha	20	0	0	20
estrogen-related nuclear receptor alpha	35	0	0	35
farnesoid X nuclear receptor	17	0	0	17
pregnane X nuclear receptor	34	0	0	34
estrogen nuclear receptor alpha	48	0	0	48
peroxisome proliferator-activated receptor delta	13	0	0	13
peroxisome proliferator activated receptor gamma	24	0	0	24
aryl hydrocarbon receptor	10	0	0	10
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a	24	0	0	24
Histone H2A.x	11	0	0	11
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 1	8	0	0	8
thyroid hormone receptor beta isoform 2	34	0	0	34
heat shock protein beta-1	12	0	0	12
mitogen-activated protein kinase 1	11	0	0	11
nuclear factor erythroid 2-related factor 2 isoform 1	30	0	0	30
Voltage-dependent calcium channel gamma-2 subunit	15	0	0	15
Cellular tumor antigen p53	25	0	0	25
Glutamate receptor 2	16	2	1	19
Nuclear receptor ROR-gamma	4	0	0	4
Peroxisome proliferator-activated receptor alpha	1	0	0	1
ATPase family AAA domain-containing protein 5	19	0	0	19
Ataxin-2	29	0	0	29
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE	12	0	0	12
Chain A, TYROSYL-DNA PHOSPHODIESTERASE	13	0	0	13
aldehyde dehydrogenase 1 family, member A1	13	0	0	13
vitamin D (1,25- dihydroxyvitamin D3) receptor	19	0	0	19
thyroid hormone receptor beta isoform a	8	0	0	8
cytochrome P450 3A4 isoform 1	15	0	0	15
Gamma-aminobutyric acid receptor subunit pi	15	14	2	31
Gamma-aminobutyric acid receptor subunit beta-1	15	14	2	31
Gamma-aminobutyric acid receptor subunit delta	15	14	2	31
Gamma-aminobutyric acid receptor subunit gamma-2	15	14	3	32
Gamma-aminobutyric acid receptor subunit alpha-5	15	14	2	31
Gamma-aminobutyric acid receptor subunit alpha-3	15	14	2	31
Gamma-aminobutyric acid receptor subunit gamma-1	15	14	2	31
Gamma-aminobutyric acid receptor subunit alpha-2	15	14	2	31
Gamma-aminobutyric acid receptor subunit alpha-4	15	14	2	31
Gamma-aminobutyric acid receptor subunit gamma-3	15	14	2	31
Gamma-aminobutyric acid receptor subunit alpha-6	15	14	2	31
Gamma-aminobutyric acid receptor subunit alpha-1	15	15	3	33
Gamma-aminobutyric acid receptor subunit beta-3	15	14	2	31
Gamma-aminobutyric acid receptor subunit beta-2	15	14	3	32
GABA theta subunit	15	14	2	31
Gamma-aminobutyric acid receptor subunit epsilon	15	14	2	31
lamin isoform A-delta10	29	0	0	29
Cytochrome P450 2A6	0	3	0	3
Cytochrome P450 2A5	0	1	0	1
5-hydroxytryptamine receptor 2C	0	15	2	17
5-hydroxytryptamine receptor 2A	0	15	2	17
5-hydroxytryptamine receptor 1A	0	22	2	24
5-hydroxytryptamine receptor 1B	0	16	1	17
5-hydroxytryptamine receptor 1D	0	6	1	7
5-hydroxytryptamine receptor 1F	0	6	1	7
5-hydroxytryptamine receptor 2B	0	14	3	17
5-hydroxytryptamine receptor 6	0	2	1	3
Sodium-dependent serotonin transporter	0	25	5	30
Sodium-dependent serotonin transporter	0	16	1	17
5-hydroxytryptamine receptor 7	0	7	1	8
5-hydroxytryptamine receptor 5A	0	2	1	3
5-hydroxytryptamine receptor 5B	0	2	1	3
5-hydroxytryptamine receptor 3A	0	3	1	4
5-hydroxytryptamine receptor 4	0	2	1	3
5-hydroxytryptamine receptor 3B	0	3	1	4
Chain A, CARBONIC ANHYDRASE II	0	0	1	1
Chain A, CARBONIC ANHYDRASE II	0	0	1	1
Chain A, CARBONIC ANHYDRASE II	0	0	1	1
Chain A, Carbonic Anhydrase Ii	0	0	1	1
Chain A, Carbonic Anhydrase Ii	0	0	1	1
Chain A, Beta-lactamase	11	0	0	11
Chain A, Endochitinase	0	1	0	1
Chain A, Endochitinase	0	1	0	1
Chain A, Endochitinase	0	1	0	1
Chain A, Class Iii Chitinase Chia1	0	1	0	1
Chain A, Carbonic anhydrase 13	0	1	0	1
Chain A, Carbonic anhydrase II	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Chain A, Carbonic anhydrase	0	1	0	1
Chain B, Carbonic anhydrase	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Carbonic anhydrase	0	0	0	2
Carbonic anhydrase	0	2	0	2
thioredoxin reductase	19	0	0	19
GALC protein	2	0	0	2
cytochrome P450 family 3 subfamily A polypeptide 4	26	0	0	26
Carbonic anhydrase	0	2	0	2
Carbonic anhydrase	0	2	0	2
arylsulfatase A	13	0	0	13
Carbonic anhydrase	0	2	0	2
euchromatic histone-lysine N-methyltransferase 2	34	0	0	34
Bloom syndrome protein isoform 1	13	0	0	13
geminin	28	0	0	28
peripheral myelin protein 22	26	0	0	26
survival motor neuron protein isoform d	17	0	0	17
muscleblind-like protein 1 isoform 1	6	0	0	6
ATP-binding cassette sub-family C member 3	0	27	0	27
Multidrug resistance-associated protein 4	0	27	0	27
Carbonic anhydrase	0	2	0	2
Solute carrier family 22 member 6	0	2	0	2
Carbonic anhydrase 12	0	4	1	10
Prolyl endopeptidase	0	2	0	2
Carbonic anhydrase-related protein 11	0	1	0	2
Bile salt export pump	0	40	0	40
Glycogen phosphorylase, muscle form	0	1	0	1
Renin	0	2	0	2
Carbonic anhydrase 1	0	9	1	18
Carbonic anhydrase 2	0	9	2	18
Carbonic anhydrase 2	0	3	0	3
Cytochrome P450 1A2	0	1	1	3
Carbonic anhydrase 3	0	4	1	9
Cathepsin B	0	1	0	1
Cytochrome P450 3A4	0	12	1	16
Steryl-sulfatase	0	1	0	1
Polyunsaturated fatty acid 5-lipoxygenase	0	2	0	2
Cytochrome P450 2C8	0	3	0	3
Cytochrome P450 2D6	0	15	1	17
Cytochrome P450 2C9	0	15	0	16
Androgen receptor	0	6	0	6
Translocator protein	0	5	2	8
Cannabinoid receptor 1	0	1	0	1
Arachidonate 5-lipoxygenase-activating protein	0	2	0	2
Cytochrome P450 2B6	0	2	1	3
Carbonic anhydrase 4	0	5	1	10
Carbonic anhydrase 6	0	5	1	10
Carbonic anhydrase 5A, mitochondrial	0	1	0	1
Adenosine receptor A1	0	4	0	6
Serum paraoxonase/arylesterase 1	0	2	0	2
Dipeptidyl peptidase 4	0	0	0	1
Endochitinase	0	1	0	1
Adenosine receptor A2a	0	2	1	5
Delta-type opioid receptor	0	5	0	6
Cytochrome P450 2C19	0	4	0	6
Delta-type opioid receptor	0	5	1	7
Mu-type opioid receptor	0	5	1	9
Carbonic anhydrase 5A, mitochondrial	0	4	2	11
Carbonic anhydrase	0	2	0	4
Kappa-type opioid receptor	0	4	0	4
Carbonic anhydrase 7	0	4	1	9
Carbonic anhydrase	0	1	0	1
D(1A) dopamine receptor	9	2	0	11
Corticosteroid 11-beta-dehydrogenase isozyme 1	0	1	0	1
Carbonic anhydrase	0	2	0	4
D(2) dopamine receptor	0	20	3	24
Cholinesterase	0	3	0	4
Carbonic anhydrase	0	2	0	2
Mu-type opioid receptor	0	5	0	5
Fatty-acid amide hydrolase 1	0	4	0	4
Beta-carbonic anhydrase 1	0	2	0	2
Carbonic anhydrase 2	0	2	0	2
Glutamate receptor ionotropic, NMDA 2B	0	9	1	12
Squalene synthase	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-7	0	4	0	4
Carbonic anhydrase 9	0	4	1	10
Carbonic anhydrase	0	1	0	1
Carbonic anhydrase, alpha family	0	2	0	2
Carbonic anhydrase	0	2	0	4
Carbonic anhydrase 3	0	2	0	2
Carbonic anhydrase	0	1	0	4
Carbonic anhydrase	0	2	0	5
Carbonic anhydrase	0	2	0	2
Sigma intracellular receptor 2	0	6	0	6
Delta carbonic anhydrase	0	2	0	2
Sigma non-opioid intracellular receptor 1	0	5	0	5
Renin	0	1	0	1
Carbonic anhydrase	0	2	0	4
Endochitinase A1	0	1	0	1
Multidrug resistance-associated protein 1	0	1	0	1
Carbonic anhydrase 13	0	4	1	8
Canalicular multispecific organic anion transporter 1	0	26	0	26
Carbonic anhydrase 4	0	2	0	3
Carbonic anhydrase 15	0	3	0	6
Acidic mammalian chitinase	0	1	0	1
Carbonic anhydrase 13	0	2	0	6
Carbonic anhydrase 7	0	1	0	1
Carbonic anhydrase	0	1	0	1
Carbonic anhydrase 14	0	4	1	10
Carbonic anhydrase	0	1	0	1
Carbonic anhydrase 2, isoform A	0	1	0	1
Carbonic anhydrase 5B, mitochondrial	0	4	1	10
Chain A, MTA/SAH nucleosidase	0	1	0	1
Chain A, Ribosome-inactivating protein alpha-trichosanthin	0	0	1	1
Chain A, Ricin A chain	0	0	1	1
Chain A, Ribosome-inactivating protein 3	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
TDP1 protein	45	0	0	45
nuclear factor erythroid 2-related factor 2 isoform 2	11	0	0	11
importin subunit beta-1 isoform 1	2	0	0	2
snurportin-1	2	0	0	2
tumor susceptibility gene 101 protein	1	0	0	1
GTP-binding nuclear protein Ran isoform 1	2	0	0	2
Cyclin-dependent kinase 1	0	1	1	2
Heat shock protein HSP 90-beta	0	1	0	1
Xanthine dehydrogenase/oxidase	0	3	0	3
TAR DNA-binding protein 43	8	0	0	8
Protein mono-ADP-ribosyltransferase PARP15	0	1	0	1
Leucine-rich repeat serine/threonine-protein kinase 2	0	2	0	2
glp-1 receptor, partial	7	0	0	7
hypoxia-inducible factor 1 alpha subunit	12	0	0	12
ATAD5 protein, partial	14	0	0	14
Fumarate hydratase	10	0	0	10
caspase 7, apoptosis-related cysteine protease	9	0	0	9
polyprotein	10	0	0	10
67.9K protein	10	0	0	10
caspase-3	9	0	0	9
IDH1	15	0	0	15
v-jun sarcoma virus 17 oncogene homolog (avian)	20	0	0	20
nuclear receptor subfamily 1, group I, member 2	4	0	0	4
cellular tumor antigen p53 isoform a	5	0	0	5
chromobox protein homolog 1	19	0	0	19
transcriptional regulator ERG isoform 3	7	0	0	7
histone deacetylase 9 isoform 3	3	0	0	3
urokinase-type plasminogen activator precursor	5	0	0	5
plasminogen precursor	5	0	0	5
urokinase plasminogen activator surface receptor precursor	5	0	0	5
Vif	0	0	0	1
DNA dC->dU-editing enzyme APOBEC-3G isoform 1	3	0	0	3
neuropeptide S receptor isoform A	6	0	0	6
Interferon beta	19	0	0	19
Integrin beta-3	4	2	0	6
Integrin alpha-IIb	4	2	0	6
Methionine aminopeptidase	0	1	0	1
Inositol monophosphatase 1	9	0	0	9
ras-related protein Rab-9A	8	0	0	8
Polyphenol oxidase 2	0	1	0	1
Hypoxanthine-guanine phosphoribosyltransferase	0	0	0	2
Xanthine dehydrogenase/oxidase [Includes: Xanthine dehydrogenase	0	1	0	1
Adenosine receptor A2a	0	0	1	1
Nuclear receptor ROR-gamma	0	1	0	1
Xanthine dehydrogenase/oxidase	0	2	1	4
Purine nucleoside phosphorylase	0	0	1	1
Shiga toxin subunit A	0	2	0	2
Histamine H3 receptor	0	1	0	1
flap endonuclease 1	8	0	0	8
Glutamate receptor ionotropic, NMDA 2D	0	3	0	3
Glutamate receptor ionotropic, NMDA 3B	0	3	0	3
Glutamate receptor 1	1	2	1	4
Glutamate receptor 3	1	2	1	4
Glutamate receptor 4	1	2	1	4
Glutamate receptor ionotropic, kainate 1	0	2	0	2
Glutamate receptor 1	0	1	1	2
Glutamate receptor 2	0	1	0	1
Glutamate receptor ionotropic, NMDA 1	0	8	1	11
Glutamate receptor ionotropic, kainate 1	0	2	0	2
Glutamate receptor ionotropic, kainate 2	0	2	0	2
Glutamate receptor 1	0	2	1	3
Glutamate receptor 2	0	2	1	3
Glutamate receptor 3	0	2	0	2
Glutamate receptor ionotropic, kainate 3	0	1	0	1
Excitatory amino acid transporter 1	0	1	0	1
Excitatory amino acid transporter 2	0	1	0	1
Excitatory amino acid transporter 3	0	1	0	1
Glutamate receptor 4	0	2	0	2
Glutamate receptor ionotropic, NMDA 2A	0	8	1	11
Glutamate receptor ionotropic, NMDA 2C	0	8	1	11
Glutamate receptor ionotropic, kainate 4	0	1	0	1
Glutamate receptor ionotropic, NMDA 1	0	3	0	3
Glutamate receptor ionotropic, NMDA 2A	0	3	0	3
Glutamate receptor ionotropic, kainate 2	0	2	0	2
Glutamate receptor ionotropic, kainate 3	0	1	0	1
Glutamate receptor ionotropic, NMDA 2B	0	3	0	3
Glutamate receptor ionotropic, NMDA 2C	0	3	0	3
Glutamate receptor ionotropic, kainate 4	0	1	0	1
Glutamate receptor ionotropic, kainate 5	0	1	0	1
Glutamate receptor ionotropic, NMDA 2D	0	8	1	11
Glutamate receptor ionotropic, kainate 5	0	1	0	1
Glutamate receptor ionotropic, NMDA 3A	0	3	0	3
Glutamate receptor ionotropic, NMDA 3B	0	8	1	11
Glutamate receptor ionotropic, NMDA 3A	0	8	1	11
Glutamate receptor 4	0	1	0	1
Glutamate receptor 3	0	1	0	1
nuclear receptor ROR-gamma isoform 1	12	0	0	12
Bromodomain-containing protein 4	0	0	1	1
Gamma-aminobutyric acid receptor subunit alpha-1	0	9	7	16
Gamma-aminobutyric acid receptor subunit gamma-2	0	9	5	14
Cholecystokinin receptor type A	0	2	0	2
Gamma-aminobutyric acid receptor subunit alpha-5	0	8	7	15
Gamma-aminobutyric acid receptor subunit alpha-3	0	8	6	14
Gamma-aminobutyric acid receptor subunit alpha-2	0	8	5	13
Gamma-aminobutyric acid receptor subunit beta-2	0	8	4	12
Cholecystokinin receptor type A	0	3	0	3
acetylcholinesterase	17	0	0	17
NFKB1 protein, partial	8	0	0	8
signal transducer and activator of transcription 6, interleukin-4 induced	1	0	0	1
regulator of G-protein signaling 4	17	0	0	17
EWS/FLI fusion protein	14	0	0	14
putative alpha-glucosidase	1	0	0	1
histone acetyltransferase KAT2A isoform 1	10	0	0	10
Solute carrier family 22 member 2	0	6	0	8
Solute carrier family 22 member 1	0	13	0	16
Matrix protein 2	0	1	1	2
Matrix protein 2	0	1	2	3
Spike glycoprotein	20	2	3	25
Solute carrier family 22 member 1	0	8	0	10
Multidrug and toxin extrusion protein 1	0	6	0	6
Solute carrier family 22 member 2	0	6	0	7
ATP-dependent phosphofructokinase	11	0	0	11
Microtubule-associated protein tau	15	0	0	15
D(1A) dopamine receptor	17	0	0	17
Chain A, JmjC domain-containing histone demethylation protein 3A	6	0	0	6
5-hydroxytryptamine receptor 3E	0	2	0	2
SMAD family member 2	4	0	0	4
USP1 protein, partial	12	0	0	12
PPM1D protein	3	0	0	3
SMAD family member 3	4	0	0	4
G	15	0	0	15
cytochrome P450 2D6	21	0	0	21
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)	5	0	0	5
thyroid stimulating hormone receptor	10	0	0	10
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a	9	0	0	9
lysosomal alpha-glucosidase preproprotein	1	0	0	1
mu-type opioid receptor isoform MOR-1	0	0	1	1
potassium voltage-gated channel subfamily H member 2 isoform d	16	0	0	16
5-hydroxytryptamine receptor 2A	0	0	1	1
5-hydroxytryptamine receptor 3A	0	2	1	3
5-hydroxytryptamine receptor 3B	0	2	0	2
HLA class I histocompatibility antigen, B alpha chain	15	0	0	15
ATP-dependent translocase ABCB1	0	16	0	22
5-hydroxytryptamine receptor 1A	0	11	4	15
Neuronal acetylcholine receptor subunit alpha-4	1	2	0	3
Neuronal acetylcholine receptor subunit beta-2	1	2	0	3
D(2) dopamine receptor	0	20	5	31
Alpha-1B adrenergic receptor	0	16	1	17
Alpha-2C adrenergic receptor	0	21	1	22
D	0	15	0	15
Muscarinic acetylcholine receptor M3	0	17	1	18
D(1A) dopamine receptor	0	14	1	18
D(4) dopamine receptor	0	10	2	17
D(1B) dopamine receptor	0	6	0	9
Alpha-1D adrenergic receptor	0	15	1	16
Alpha-1D adrenergic receptor	0	17	1	18
5-hydroxytryptamine receptor 2A	0	23	2	27
5-hydroxytryptamine receptor 2C	0	23	2	25
D(4) dopamine receptor	0	13	0	13
Histamine H1 receptor	0	4	1	5
5-hydroxytryptamine receptor 7	0	8	0	8
Alpha-1A adrenergic receptor	0	8	1	9
Histamine H1 receptor	0	16	3	21
Alpha-1B adrenergic receptor	0	5	1	6
D(3) dopamine receptor	0	17	4	27
5-hydroxytryptamine receptor 2B	0	19	1	20
Alpha-1A adrenergic receptor	0	16	2	18
5-hydroxytryptamine receptor 3A	0	3	0	3
5-hydroxytryptamine receptor 6	0	17	0	18
3-hydroxy-3-methylglutaryl-coenzyme A reductase	0	4	0	4
Potassium voltage-gated channel subfamily H member 2	0	31	0	31
5-hydroxytryptamine receptor 3D	0	2	0	2
Multidrug and toxin extrusion protein 2	0	3	0	3
5-hydroxytryptamine receptor 3C	0	2	0	2
Inositol hexakisphosphate kinase 1	15	0	0	15
Histamine H3 receptor	0	6	0	6
cytochrome P450 2C9, partial	15	0	0	15
Chain A, Phospholipase A2 isoform 3	0	0	1	1
Chain A, 2-oxoglutarate Oxygenase	4	0	0	4
GTP-binding protein (rab7)	0	0	1	1
ras protein, partial	0	0	1	1
GLS protein	14	0	0	14
hypothetical protein, conserved	1	0	0	1
glucocerebrosidase	5	0	0	5
Rac1 protein	0	0	1	1
cell division cycle 42 (GTP binding protein, 25kDa), partial	0	0	1	1
DNA polymerase iota isoform a (long)	6	0	0	6
DNA polymerase kappa isoform 1	6	0	0	6
muscarinic acetylcholine receptor M1	15	0	0	15
lethal factor (plasmid)	7	0	0	7
Prostaglandin-H2 D-isomerase	0	1	0	1
Prostaglandin G/H synthase 1	0	1	0	1
Prostaglandin G/H synthase 2	0	1	0	1
Epidermal growth factor receptor	0	4	1	5
Fatty acid-binding protein, liver	0	4	0	4
Myeloperoxidase	0	2	0	2
Prostaglandin G/H synthase 1	0	4	0	4
Seed linoleate 13S-lipoxygenase-1	0	1	0	1
Glutathione hydrolase 1 proenzyme	0	1	0	1
Prostaglandin G/H synthase 1	0	4	0	4
Substance-P receptor	0	1	0	1
Prostaglandin G/H synthase 2	0	5	0	5
Urotensin-2 receptor	0	1	0	1
4-aminobutyrate aminotransferase, mitochondrial	0	1	0	1
Ras-related protein Rab-2A	0	0	1	1
Prostaglandin G/H synthase 2	0	1	0	1
Rho-associated protein kinase 2	0	1	0	1
Nicotinate phosphoribosyltransferase	0	2	0	2
Solute carrier family 22 member 20	0	1	0	1
Solute carrier family 22 member 6	0	1	0	1
Sigma non-opioid intracellular receptor 1	0	19	1	20
Sigma non-opioid intracellular receptor 1	0	7	1	8
Spike glycoprotein	0	2	3	5
Replicase polyprotein 1ab	0	2	3	5
Polyunsaturated fatty acid lipoxygenase ALOX15B	9	0	0	9
Transmembrane protease serine 2	0	2	3	5
5-hydroxytryptamine receptor 4	0	20	0	20
Procathepsin L	0	2	3	5
Aldo-keto reductase family 1 member B1	0	19	0	19
Muscarinic acetylcholine receptor M2	0	15	1	16
Muscarinic acetylcholine receptor M4	0	14	1	15
Muscarinic acetylcholine receptor M1	0	7	0	7
Muscarinic acetylcholine receptor M5	0	17	0	17
Alpha-2A adrenergic receptor	0	21	2	23
Replicase polyprotein 1a	0	2	3	5
Replicase polyprotein 1ab	0	2	3	5
Replicase polyprotein 1ab	0	2	4	6
Replicase polyprotein 1ab	0	2	4	6
Muscarinic acetylcholine receptor M2	0	8	0	8
Muscarinic acetylcholine receptor M1	0	18	1	19
Alpha-2B adrenergic receptor	0	22	1	23
Sodium-dependent noradrenaline transporter	0	24	4	28
Sodium-dependent dopamine transporter	0	17	1	18
Histamine H2 receptor	0	13	2	15
Histamine H2 receptor	13	2	0	17
Sodium-dependent dopamine transporter	0	17	3	20
Angiotensin-converting enzyme 2	0	2	3	5
Genome polyprotein	0	1	1	2
dopamine D1 receptor	4	0	0	4
vitamin D3 receptor isoform VDRA	10	0	0	10
serine/threonine-protein kinase mTOR isoform 1	12	0	0	12
peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	2	0	0	2
ATP-dependent translocase ABCB1	0	3	0	3
Beta-1 adrenergic receptor	0	2	0	2
D(3) dopamine receptor	0	14	1	15
Alpha-2B adrenergic receptor	0	13	1	14
ATP-dependent translocase ABCB1	0	3	0	3
Alpha-2C adrenergic receptor	0	13	1	14
Alpha-2A adrenergic receptor	0	13	1	14
D(1B) dopamine receptor	0	12	0	12
Alpha-synuclein	1	1	0	2
cytochrome P450 2D6 isoform 1	13	0	0	13
N-acetyltransferase Eis	0	4	0	4
Liver carboxylesterase 1	0	1	0	2
Vpr	3	0	0	3
Bile salt export pump	0	6	0	6
Albumin	0	0	8	8
Major prion protein	0	0	5	5
Sodium channel protein type 1 subunit alpha	0	2	0	2
Sodium channel protein type 2 subunit alpha	0	2	0	2
Sodium channel protein type 3 subunit alpha	0	1	0	1
UDP-glucuronosyltransferase 2B7	0	3	0	7
Sodium channel protein type 4 subunit alpha	0	5	0	7
Cytochrome P450 2J2	0	10	0	11
Sodium channel protein type 9 subunit alpha	0	6	0	6
Frizzled-8	0	0	1	1
P2X purinoceptor 4	0	2	0	2
Mitogen-activated protein kinase 3	0	1	1	2
Acid ceramidase	0	1	0	1
Acid ceramidase	0	1	0	1
Sulfide:quinone oxidoreductase, mitochondrial	0	1	0	1
Chain A, Ferritin light chain	7	0	0	7
activating transcription factor 6	9	0	0	9
thyrotropin-releasing hormone receptor	2	0	0	2
Caspase-2	0	0	1	1
Proteasome subunit beta type-11	0	0	0	1
phosphopantetheinyl transferase	6	0	0	6
Thrombopoietin	7	0	0	7
Smad3	6	0	0	6
NADPH oxidase 1	0	3	0	3
Snq2p	0	0	0	6
Adenylate cyclase type 1	0	4	0	4
Caspase-7	4	0	0	4
caspase-3	4	0	0	4
atrial natriuretic peptide receptor 2 precursor	10	0	0	10
M-phase phosphoprotein 8	9	0	0	9
Proteasome subunit alpha type-7	0	0	0	1
Transient receptor potential cation channel subfamily V member 1	0	2	0	2
Voltage-dependent L-type calcium channel subunit alpha-1F	0	9	0	9
Potassium channel subfamily K member 2	0	4	0	4
Albumin	0	0	6	7
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1	0	2	0	2
Receptor tyrosine-protein kinase erbB-2	0	1	0	1
Major prion protein	0	0	1	1
Tyrosine-protein kinase Fyn	0	1	1	2
Muscarinic acetylcholine receptor M3	0	6	0	6
Muscarinic acetylcholine receptor M4	0	6	0	6
Muscarinic acetylcholine receptor M5	0	7	0	7
Cys-loop ligand-gated ion channel	0	1	0	1
Calmodulin-1	0	3	2	5
Polyunsaturated fatty acid lipoxygenase ALOX15	0	2	0	2
Angiotensin-converting enzyme	0	19	0	19
Sphingomyelin phosphodiesterase	0	2	0	2
D(2) dopamine receptor	0	6	0	6
Proteasome subunit beta type-1	0	0	0	1
Substance-K receptor	0	2	0	2
Adenylate cyclase type 3	0	4	0	4
UDP-glucuronosyltransferase 1A4	0	1	0	6
Proteasome subunit alpha type-1	0	0	0	1
Proteasome subunit alpha type-2	0	0	0	1
Proteasome subunit alpha type-3	0	0	0	1
Proteasome subunit alpha type-4	0	0	0	1
Adenylate cyclase type 2	0	4	0	4
Adenylate cyclase type 4	0	4	0	4
Proteasome subunit beta type-8	0	0	0	1
Proteasome subunit beta type-9	0	0	0	1
Proteasome subunit alpha type-5	0	0	0	1
Proteasome subunit beta type-4	0	0	0	1
Proteasome subunit beta type-6	0	0	0	1
Proteasome subunit beta type-5	0	0	0	1
Trypanothione reductase	0	6	0	6
Melanocortin receptor 4	0	2	0	2
Melanocortin receptor 5	0	4	0	4
Pleiotropic ABC efflux transporter of multiple drugs	0	6	0	12
Mu-type opioid receptor	0	8	2	11
Sodium channel protein type 1 subunit alpha	0	5	0	5
Adenylate cyclase type 8	0	4	0	4
Proteasome subunit beta type-10	0	0	0	1
Delta-type opioid receptor	0	6	1	8
Kappa-type opioid receptor	0	5	1	7
Melanocortin receptor 3	0	2	0	2
Proteasome subunit beta type-3	0	0	0	1
Proteasome subunit beta type-2	0	0	0	1
5-hydroxytryptamine receptor 7	0	8	0	8
Gastrin/cholecystokinin type B receptor	0	3	0	3
Proteasome subunit alpha type-6	0	0	1	2
Calmodulin	0	1	3	4
Aldehyde oxidase 1	0	1	0	1
Sodium channel protein type 7 subunit alpha	0	3	0	3
Voltage-dependent L-type calcium channel subunit alpha-1D	0	9	0	9
Adenylate cyclase type 6	0	4	0	4
Adenylate cyclase type 5	0	4	0	4
Aldehyde oxidase	0	3	0	3
Voltage-dependent L-type calcium channel subunit alpha-1S	0	9	0	9
Voltage-dependent L-type calcium channel subunit alpha-1C	0	9	0	9
Sodium channel protein type 5 subunit alpha	0	8	0	8
Nuclear receptor subfamily 3 group C member 3	0	18	0	18
Adenylyl cyclase 7	0	4	0	4
Proteasome subunit alpha-type 8	0	0	0	1
D	0	6	0	6
Sodium channel protein type 2 subunit alpha	0	5	0	5
Proteasome subunit beta type-7	0	0	0	1
Sodium channel protein type 3 subunit alpha	0	5	0	5
Sodium channel protein type 11 subunit alpha	0	3	0	3
Sodium channel protein type 8 subunit alpha	0	3	0	3
Sodium channel protein type 10 subunit alpha	0	3	0	3
Chain A, Cruzipain	1	0	0	1
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)	5	0	0	5
Beta-1 adrenergic receptor	0	1	1	2
Alpha-1B adrenergic receptor	0	0	1	1
cytochrome P450 2C19 precursor	8	0	0	8
cytochrome P450 2C9 precursor	6	0	0	6
Membrane primary amine oxidase	0	1	0	1
Solute carrier family 22 member 3	0	4	0	4
Alpha-1A adrenergic receptor	0	0	1	1
Amine oxidase [flavin-containing] A	0	4	0	4
Amine oxidase [flavin-containing] B	0	5	0	5
Adenosine receptor A2b	0	0	1	1
Alpha-2B adrenergic receptor	0	0	0	1
Alpha-2C adrenergic receptor	0	0	0	1
Alpha-2A adrenergic receptor	0	0	0	1
Alpha-2A adrenergic receptor	0	1	0	1
Nischarin	0	2	0	2
Nischarin	0	1	0	1
bromodomain adjacent to zinc finger domain 2B	7	0	0	7
peripheral myelin protein 22 isoform 1	7	0	0	7
DNA polymerase beta	1	0	0	1
short transient receptor potential channel 6 isoform 1	0	0	1	1
transient receptor potential cation channel subfamily V member 1	3	0	0	3
Beta-2 adrenergic receptor	0	4	0	4
Beta-1 adrenergic receptor	0	3	0	3
Endothelin receptor type B	0	1	0	1
5-hydroxytryptamine receptor 3A	0	2	0	2
Endothelin receptor type B	0	1	0	1
Beta-3 adrenergic receptor	0	2	0	2
Histamine H1 receptor	0	6	0	6
5-hydroxytryptamine receptor 2C	0	4	0	4
5-hydroxytryptamine receptor 2A	0	3	0	3
5-hydroxytryptamine receptor 5A	0	2	0	2
D(2) dopamine receptor	0	2	0	2
D(3) dopamine receptor	0	2	0	2
D(2) dopamine receptor	0	3	0	3
5-hydroxytryptamine receptor 2B	0	3	0	3
5-hydroxytryptamine receptor 4	0	2	0	2
Transporter	0	4	0	4
5-hydroxytryptamine receptor 1A	0	2	0	2
Histamine H4 receptor	0	2	2	4
Transporter	0	11	0	11
endonuclease IV	6	0	0	6
pregnane X receptor	5	0	0	5
atrial natriuretic peptide receptor 1 precursor	3	0	0	3
Glucocorticoid receptor	0	8	2	15
Sex hormone-binding globulin	0	0	1	1
Glycine receptor subunit alpha-1	0	8	0	8
Corticosteroid-binding globulin	0	2	0	2
Glycine receptor subunit beta	0	8	0	8
Glycine receptor subunit alpha-2	0	8	0	8
Glycine receptor subunit alpha-3	0	8	0	8
Potassium voltage-gated channel subfamily A member 1	0	0	1	1
huntingtin isoform 2	3	0	0	3
Solute carrier family 22 member 3	0	1	0	1
Tryptophan 5-hydroxylase 1	0	2	0	2
Voltage-dependent N-type calcium channel subunit alpha-1B	0	2	0	2
Histamine H3 receptor	0	1	0	1
Solute carrier family 22 member 4	0	1	0	1
Gamma-aminobutyric acid	0	2	1	3
Gamma-aminobutyric acid receptor subunit pi	0	6	0	6
Gamma-aminobutyric acid receptor subunit delta	0	6	0	6
Alpha-1-acid glycoprotein 1	0	0	0	1
Gamma-aminobutyric acid receptor subunit alpha-1	0	4	0	5
Gamma-aminobutyric acid receptor subunit beta-1	0	4	0	5
Gamma-aminobutyric acid receptor subunit alpha-2	0	4	0	5
Gamma-aminobutyric acid receptor subunit alpha-3	0	4	0	5
Gamma-aminobutyric acid receptor subunit alpha-6	0	2	1	3
Gamma-aminobutyric acid receptor subunit beta-1	0	7	2	9
Gamma-aminobutyric acid receptor subunit alpha-4	0	4	0	5
Gamma-aminobutyric acid receptor subunit gamma-2	0	4	0	5
Gamma-aminobutyric acid receptor subunit gamma-2	0	2	1	3
Gamma-aminobutyric acid receptor subunit delta	0	2	1	3
Gamma-aminobutyric acid receptor subunit alpha-2	0	2	1	3
Gamma-aminobutyric acid receptor subunit alpha-3	0	2	1	3
Gamma-aminobutyric acid receptor subunit gamma-3	0	2	1	3
Gamma-aminobutyric acid receptor subunit beta-3	0	8	4	12
Translocator protein	0	1	0	1
Translocator protein	0	3	0	3
Gastrin/cholecystokinin type B receptor	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-4	0	7	2	9
Gamma-aminobutyric acid receptor subunit beta-1	0	2	1	3
Gamma-aminobutyric acid receptor subunit alpha-1	0	2	1	3
Gamma-aminobutyric acid receptor subunit beta-3	0	2	1	3
Gamma-aminobutyric acid receptor subunit epsilon	0	6	0	6
Gamma-aminobutyric acid receptor subunit alpha-6	0	7	2	9
Gamma-aminobutyric acid receptor subunit alpha-5	0	2	1	3
Gamma-aminobutyric acid receptor subunit gamma-1	0	6	0	6
Gamma-aminobutyric acid receptor subunit pi	0	2	1	3
Sphingosine-1-phosphate lyase 1	0	2	0	2
Gamma-aminobutyric acid receptor subunit gamma-3	0	6	0	6
Gamma-aminobutyric acid receptor subunit alpha-4	0	2	1	3
Gamma-aminobutyric acid receptor subunit theta	0	2	1	3
Gamma-aminobutyric acid receptor subunit gamma-1	0	2	1	3
Gamma-aminobutyric acid receptor subunit theta	0	6	0	6
Chain A, Putative fructose-1,6-bisphosphate aldolase	3	0	0	3
Chain A, ATP-DEPENDENT DNA HELICASE Q1	3	0	0	3
15-lipoxygenase, partial	3	0	0	3
polyunsaturated fatty acid lipoxygenase ALOX12	1	0	0	1
runt-related transcription factor 1 isoform AML1b	1	0	0	1
core-binding factor subunit beta isoform 2	1	0	0	1
Caspase-7	1	0	0	1
Bone morphogenetic protein receptor type-1B	0	0	1	1
Cell division cycle 7-related protein kinase	0	0	1	1
Serine/threonine-protein kinase PLK4	0	0	1	1
ATP-dependent RNA helicase DDX3X	0	0	1	1
Pyridoxal kinase	0	0	1	1
Citron Rho-interacting kinase	0	0	1	1
Serine/threonine-protein kinase Chk1	0	0	1	1
Aurora kinase A	0	0	1	1
Cyclin-G-associated kinase	0	0	1	1
Ephrin type-B receptor 6	0	0	1	1
Peroxisomal acyl-coenzyme A oxidase 3	0	0	1	1
Receptor-interacting serine/threonine-protein kinase 2	0	0	1	1
Mitotic checkpoint serine/threonine-protein kinase BUB1	0	0	1	1
Dynamin-like 120 kDa protein, mitochondrial	0	0	1	1
Eukaryotic translation initiation factor 5B	0	0	1	1
Rho-associated protein kinase 2	0	0	1	1
Serine/threonine-protein kinase ULK1	0	0	1	1
Serine/threonine-protein kinase/endoribonuclease IRE1	0	0	1	1
Ribosomal protein S6 kinase alpha-5	0	0	1	1
U5 small nuclear ribonucleoprotein 200 kDa helicase	0	0	1	1
Ribosomal protein S6 kinase alpha-4	0	0	1	1
Serine/threonine-protein kinase 16	0	0	1	1
Serine/threonine-protein kinase 10	0	0	1	1
Serine/threonine-protein kinase D3	0	0	1	1
Structural maintenance of chromosomes protein 2	0	0	1	1
Mitogen-activated protein kinase kinase kinase 6	0	0	1	1
Mitogen-activated protein kinase kinase kinase kinase 4	0	0	1	1
Serine/threonine-protein kinase LATS1	0	0	1	1
Serine/threonine-protein kinase PAK 4	0	0	1	1
Tyrosine-protein kinase ABL1	0	0	1	1
High affinity nerve growth factor receptor	0	0	1	1
Guanine nucleotide-binding protein G(i) subunit alpha-2	0	0	1	1
ADP/ATP translocase 2	0	0	1	1
Protein kinase C beta type	0	0	1	1
Insulin receptor	0	0	1	1
Tyrosine-protein kinase Lck	0	0	1	1
Glycogen phosphorylase, liver form	0	0	1	1
Tyrosine-protein kinase Fes/Fps	0	0	1	1
Adenine phosphoribosyltransferase	0	0	1	1
Tyrosine-protein kinase Yes	0	0	1	1
Tyrosine-protein kinase Lyn	0	0	1	1
Proto-oncogene tyrosine-protein kinase receptor Ret	0	0	1	1
Insulin-like growth factor 1 receptor	0	0	1	1
Signal recognition particle receptor subunit alpha	0	0	1	1
Cytochrome c1, heme protein, mitochondrial	0	0	1	1
Hepatocyte growth factor receptor	0	0	1	1
Tyrosine-protein kinase HCK	0	0	1	1
Platelet-derived growth factor receptor beta	0	0	1	1
Tyrosine-protein kinase Fgr	0	0	1	1
Serine/threonine-protein kinase A-Raf	0	0	1	1
Glycogen phosphorylase, brain form	0	0	1	1
Breakpoint cluster region protein	0	0	1	1
Serine/threonine-protein kinase pim-1	0	0	1	1
Fibroblast growth factor receptor 1	0	0	1	1
DNA topoisomerase 2-alpha	0	0	1	1
Cyclin-dependent kinase 4	0	0	1	1
ADP/ATP translocase 3	0	0	1	1
Inosine-5'-monophosphate dehydrogenase 2	0	0	1	1
Proto-oncogene tyrosine-protein kinase Src	0	0	1	1
cAMP-dependent protein kinase type II-alpha regulatory subunit	0	0	1	1
Serine/threonine-protein kinase B-raf	0	0	1	1
Potassium voltage-gated channel subfamily E member 1	0	1	0	1
Phosphorylase b kinase gamma catalytic chain, liver/testis isoform	0	0	1	1
Ribosyldihydronicotinamide dehydrogenase [quinone]	0	0	1	1
Tyrosine-protein kinase Fer	0	0	1	1
Protein kinase C alpha type	0	0	1	1
cAMP-dependent protein kinase catalytic subunit alpha	0	0	1	1
General transcription and DNA repair factor IIH helicase subunit XPD	0	0	1	1
Casein kinase II subunit alpha'	0	0	1	1
Ras-related protein Rab-6A	0	0	1	1
Ephrin type-A receptor 1	0	0	1	1
Multifunctional protein ADE2	0	0	1	1
cAMP-dependent protein kinase catalytic subunit gamma	0	0	1	1
cAMP-dependent protein kinase catalytic subunit beta	0	0	1	1
Ferrochelatase, mitochondrial	0	0	1	1
Ribosomal protein S6 kinase beta-1	0	0	1	1
Tyrosine-protein kinase JAK1	0	0	1	1
Cyclin-dependent kinase 2	0	0	1	1
Beta-adrenergic receptor kinase 1	0	1	2	3
Probable ATP-dependent RNA helicase DDX6	0	0	1	1
MAP/microtubule affinity-regulating kinase 3	0	0	1	1
Deoxycytidine kinase	0	0	1	1
Mitogen-activated protein kinase 1	0	0	1	1
Ephrin type-A receptor 2	0	0	1	1
Ephrin type-B receptor 2	0	0	1	1
Non-receptor tyrosine-protein kinase TYK2	0	0	1	1
UMP-CMP kinase	0	0	1	1
Phosphatidylethanolamine-binding protein 1	0	0	1	1
Wee1-like protein kinase	0	0	1	1
Heme oxygenase 2	0	0	1	1
S-adenosylmethionine synthase isoform type-2	0	0	1	1
DnaJ homolog subfamily A member 1	0	0	1	1
RAC-alpha serine/threonine-protein kinase	0	0	1	1
RAC-beta serine/threonine-protein kinase	0	0	1	1
Dual specificity protein kinase TTK	0	0	1	1
DNA replication licensing factor MCM4	0	0	1	1
Myosin-10	0	0	1	1
Dual specificity mitogen-activated protein kinase kinase 2	0	0	1	1
Receptor-type tyrosine-protein kinase FLT3	0	0	1	1
Bone morphogenetic protein receptor type-1A	0	0	1	1
Activin receptor type-1B	0	0	1	1
TGF-beta receptor type-1	0	0	1	1
TGF-beta receptor type-2	0	0	1	1
Electron transfer flavoprotein subunit beta	0	0	1	1
Tyrosine-protein kinase CSK	0	0	1	1
Glycine--tRNA ligase	0	0	1	1
Protein kinase C iota type	0	0	1	1
Exosome RNA helicase MTR4	0	0	1	1
Serine/threonine-protein kinase mTOR	0	2	1	3
Tyrosine-protein kinase Tec	0	0	1	1
Tyrosine-protein kinase ABL2	0	0	1	1
Tyrosine-protein kinase FRK	0	0	1	1
G protein-coupled receptor kinase 6	0	0	1	1
Tyrosine-protein kinase SYK	0	0	1	1
26S proteasome regulatory subunit 6B	0	0	1	1
Mitogen-activated protein kinase 8	0	0	1	1
Mitogen-activated protein kinase 9	0	0	1	1
Dual specificity mitogen-activated protein kinase kinase 3	0	0	1	1
Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha	0	0	1	1
Casein kinase I isoform alpha	0	0	1	1
Casein kinase I isoform delta	0	0	1	1
MAP kinase-activated protein kinase 2	0	0	1	1
Elongation factor Tu, mitochondrial	0	0	1	1
Choline-phosphate cytidylyltransferase A	0	0	1	1
Cysteine--tRNA ligase, cytoplasmic	0	0	1	1
Casein kinase I isoform epsilon	0	0	1	1
Very long-chain specific acyl-CoA dehydrogenase, mitochondrial	0	0	1	1
Dual specificity protein kinase CLK1	0	0	1	1
Dual specificity protein kinase CLK2	0	0	1	1
Dual specificity protein kinase CLK3	0	0	1	1
Glycogen synthase kinase-3 alpha	0	0	1	1
Glycogen synthase kinase-3 beta	0	0	1	1
Cyclin-dependent kinase 7	0	0	1	1
Cyclin-dependent kinase 9	0	0	1	1
Ras-related protein Rab-27A	0	0	1	1
Interleukin-1 receptor-associated kinase 1	0	0	1	1
Potassium voltage-gated channel subfamily KQT member 1	0	1	0	1
Ribosomal protein S6 kinase alpha-3	0	0	1	1
Serine/threonine-protein kinase Nek2	0	0	1	1
Serine/threonine-protein kinase Nek3	0	0	1	1
Dual specificity mitogen-activated protein kinase kinase 6	0	0	1	1
Serine/threonine-protein kinase PLK1	0	0	1	1
LIM domain kinase 1	0	0	1	1
LIM domain kinase 2	0	0	1	1
Mitogen-activated protein kinase 10	0	0	1	1
Tyrosine--tRNA ligase, cytoplasmic	0	0	1	1
5'-AMP-activated protein kinase subunit gamma-1	0	0	1	1
Ephrin type-B receptor 3	0	0	1	1
Ephrin type-A receptor 5	0	0	1	1
Ephrin type-B receptor 4	0	0	1	1
Ephrin type-A receptor 4	0	0	1	1
Adenylate kinase 2, mitochondrial	0	0	1	1
Adenosine kinase	0	0	1	1
Ras-related protein Rab-10	0	0	1	1
Actin-related protein 3	0	0	1	1
Actin-related protein 2	0	0	1	1
GTP-binding nuclear protein Ran	0	0	1	1
Casein kinase I isoform gamma-2	0	0	1	1
Cyclin-dependent kinase 3	0	0	1	1
Cyclin-dependent kinase 6	0	0	1	1
Cyclin-dependent-like kinase 5	0	0	1	1
Cyclin-dependent kinase 16	0	0	1	1
Cyclin-dependent kinase 17	0	0	1	1
ATP-dependent 6-phosphofructokinase, platelet type	0	0	1	1
Dual specificity mitogen-activated protein kinase kinase 1	0	0	1	1
DNA topoisomerase 2-beta	0	0	1	1
Protein kinase C theta type	0	0	1	1
Activin receptor type-1	0	0	1	1
Macrophage-stimulating protein receptor	0	0	1	1
Focal adhesion kinase 1	0	0	1	1
Protein kinase C delta type	0	0	1	1
Tyrosine-protein kinase BTK	0	0	1	1
Activated CDC42 kinase 1	0	0	1	1
Epithelial discoidin domain-containing receptor 1	0	0	1	1
Mitogen-activated protein kinase kinase kinase kinase 2	0	0	1	1
Serine/threonine-protein kinase 4	0	0	1	1
5'-AMP-activated protein kinase catalytic subunit alpha-1	0	0	1	1
Dual specificity mitogen-activated protein kinase kinase 5	0	0	1	1
Mitogen-activated protein kinase 7	0	0	1	1
Serine/threonine-protein kinase PAK 2	0	0	1	1
Serine/threonine-protein kinase 3	0	0	1	1
Mitogen-activated protein kinase kinase kinase 1	0	0	1	1
Integrin-linked protein kinase	0	0	1	1
Rho-associated protein kinase 1	0	0	1	1
Non-receptor tyrosine-protein kinase TNK1	0	0	1	1
Calcium/calmodulin-dependent protein kinase type II subunit gamma	0	0	1	1
Calcium/calmodulin-dependent protein kinase type II subunit delta	0	0	1	1
Dual specificity tyrosine-phosphorylation-regulated kinase 1A	0	0	1	1
Activin receptor type-2B	0	0	1	1
Bone morphogenetic protein receptor type-2	0	0	1	1
Protein-tyrosine kinase 6	0	0	1	1
cGMP-dependent protein kinase 1	0	0	1	1
Cyclin-dependent kinase 13	0	0	1	1
Inhibitor of nuclear factor kappa-B kinase subunit epsilon	0	0	1	1
Protein-tyrosine kinase 2-beta	0	0	1	1
Maternal embryonic leucine zipper kinase	0	0	1	1
Structural maintenance of chromosomes protein 1A	0	0	1	1
Chromodomain-helicase-DNA-binding protein 4	0	0	1	1
Peroxisomal acyl-coenzyme A oxidase 1	0	0	1	1
Ephrin type-A receptor 7	0	0	1	1
Delta(24)-sterol reductase	0	0	1	1
Ribosomal protein S6 kinase alpha-1	0	0	1	1
Dual specificity testis-specific protein kinase 1	0	0	1	1
Myosin light chain kinase, smooth muscle	0	0	1	1
Mitogen-activated protein kinase 11	0	0	1	1
Serine/threonine-protein kinase STK11	0	0	1	1
Serine/threonine-protein kinase N1	0	0	1	1
Serine/threonine-protein kinase N2	0	0	1	1
Mitogen-activated protein kinase 14	0	0	1	1
Calcium/calmodulin-dependent protein kinase type IV	0	0	1	1
Mitogen-activated protein kinase kinase kinase 11	0	0	1	1
Discoidin domain-containing receptor 2	0	0	1	1
AP2-associated protein kinase 1	0	0	1	1
Myosin light chain kinase 3	0	0	1	1
Putative heat shock protein HSP 90-beta 2	0	0	1	1
Serine/threonine-protein kinase MRCK alpha	0	0	1	1
Serine/threonine-protein kinase MRCK gamma	0	0	1	1
Acyl-CoA dehydrogenase family member 10	0	0	1	1
Serine/threonine-protein kinase N3	0	0	1	1
Serine/threonine-protein kinase ULK3	0	0	1	1
Uncharacterized protein FLJ45252	0	0	1	1
Acyl-CoA dehydrogenase family member 11	0	0	1	1
Serine/threonine-protein kinase/endoribonuclease IRE2	0	0	1	1
Serine/threonine-protein kinase MARK2	0	0	1	1
ATP-dependent RNA helicase DHX30	0	0	1	1
Serine/threonine-protein kinase TAO1	0	0	1	1
STE20-related kinase adapter protein alpha	0	0	1	1
Myosin-14	0	0	1	1
AarF domain-containing protein kinase 1	0	0	1	1
ATP-dependent RNA helicase DDX42	0	0	1	1
Mitogen-activated protein kinase kinase kinase kinase 3	0	0	1	1
Eukaryotic peptide chain release factor GTP-binding subunit ERF3B	0	0	1	1
Regulatory-associated protein of mTOR	0	1	0	1
Atypical kinase COQ8A, mitochondrial	0	0	1	1
Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma	0	0	1	1
Mitogen-activated protein kinase 15	0	0	1	1
Serine/threonine-protein kinase Nek9	0	0	1	1
Serine/threonine-protein kinase Nek7	0	0	1	1
ATP-dependent RNA helicase DDX1	0	0	1	1
Mitogen-activated protein kinase kinase kinase kinase 1	0	0	1	1
Aurora kinase B	0	0	1	1
MAP/microtubule affinity-regulating kinase 4	0	0	1	1
Serine/threonine-protein kinase Nek1	0	0	1	1
PAS domain-containing serine/threonine-protein kinase	0	0	1	1
Calcium/calmodulin-dependent protein kinase kinase 2	0	0	1	1
EKC/KEOPS complex subunit TP53RK	0	0	1	1
Dual specificity testis-specific protein kinase 2	0	0	1	1
Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase	0	0	1	1
Mitogen-activated protein kinase kinase kinase 5	0	0	1	1
Mitogen-activated protein kinase kinase kinase 3	0	0	1	1
Eukaryotic translation initiation factor 2-alpha kinase 1	0	0	1	1
Target of rapamycin complex subunit LST8	0	1	0	1
Nucleolar GTP-binding protein 1	0	0	1	1
Serine/threonine-protein kinase D2	0	0	1	1
NUAK family SNF1-like kinase 2	0	0	1	1
RNA cytidine acetyltransferase	0	0	1	1
Serine/threonine-protein kinase SIK2	0	0	1	1
STE20-like serine/threonine-protein kinase	0	0	1	1
Serine/threonine-protein kinase TAO3	0	0	1	1
dCTP pyrophosphatase 1	0	0	1	1
Dual specificity protein kinase CLK4	0	0	1	1
Casein kinase I isoform gamma-1	0	0	1	1
Phenylalanine--tRNA ligase beta subunit	0	0	1	1
BMP-2-inducible protein kinase	0	0	1	1
Obg-like ATPase 1	0	0	1	1
Midasin	0	0	1	1
Interleukin-1 receptor-associated kinase 4	0	0	1	1
Mitogen-activated protein kinase kinase kinase 20	0	0	1	1
Cyclin-dependent kinase 12	0	0	1	1
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13	0	0	1	1
Serine/threonine-protein kinase 26	0	0	1	1
Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial	0	0	1	1
Serine/threonine-protein kinase NLK	0	0	1	1
5'-AMP-activated protein kinase subunit gamma-2	0	0	1	1
Serine/threonine-protein kinase TBK1	0	0	1	1
Septin-9	0	0	1	1
Potassium voltage-gated channel subfamily D member 3	0	1	0	1
Ribosomal protein S6 kinase alpha-6	0	0	1	1
TRAF2 and NCK-interacting protein kinase	0	0	1	1
Serine/threonine-protein kinase TAO2	0	0	1	1
Long-chain-fatty-acid--CoA ligase 5	0	0	1	1
RAC-gamma serine/threonine-protein kinase	0	0	1	1
Serine/threonine-protein kinase SIK3	0	0	1	1
Mitogen-activated protein kinase kinase kinase 2	0	0	1	1
Thyroid hormone receptor-associated protein 3	0	0	1	1
Mitogen-activated protein kinase kinase kinase kinase 5	0	0	1	1
Receptor-interacting serine/threonine-protein kinase 3	0	0	1	1
Serine/threonine-protein kinase MRCK beta	0	0	1	1
Interleukin-1 receptor-associated kinase 3	0	0	1	1
Casein kinase I isoform gamma-3	0	0	1	1
Mitogen-activated protein kinase kinase kinase 4	0	0	1	1
Sphingosine 1-phosphate receptor 1	0	0	1	1
RCG53912, isoform CRA_a	0	0	0	1
Sphingosine kinase 1	0	0	0	1
Sphingosine kinase 2	0	0	0	1
Sphingosine kinase 1	0	0	0	1
Chain A, Uracil Phosphoribosyltransferase	0	1	0	1
Skn7p	0	0	0	1
nonstructural protein 1	6	0	0	6
hemoglobin subunit beta	1	0	0	1
Solute carrier family 22 member 8	0	0	0	1
Amyloid-beta precursor protein	1	0	0	1
Thymidylate synthase	0	1	0	1
Aromatase	0	1	0	1
HSP40, subfamily A [Plasmodium falciparum 3D7]	0	0	0	1
NPC intracellular cholesterol transporter 1 precursor	6	0	0	6
Sodium-dependent noradrenaline transporter	0	3	0	3
Dipeptidyl peptidase 4	0	1	0	1
Acetylcholinesterase	0	2	0	2
Acetylcholinesterase	0	2	0	3
Potassium voltage-gated channel subfamily C member 1	0	1	0	1
cAMP-specific 3',5'-cyclic phosphodiesterase 4A	0	1	0	1
Gastrin/cholecystokinin type B receptor	0	1	0	1
cAMP-specific 3',5'-cyclic phosphodiesterase 4B	0	1	0	1
cAMP-specific 3',5'-cyclic phosphodiesterase 4D	0	1	0	1
Cytochrome P450 1B1	0	1	0	1
Sodium-dependent serotonin transporter	0	3	0	3
Sodium-dependent dopamine transporter	0	3	0	3
Beta-2 adrenergic receptor	0	2	0	2
Cytochrome P450 1A2	0	1	0	1
Gamma-aminobutyric acid receptor subunit rho-3	0	0	1	1
Hsf1 protein	0	0	1	1
histone-lysine N-methyltransferase 2A isoform 2 precursor	2	0	0	2
Histone deacetylase 3	0	3	0	3
Gamma-aminobutyric acid type B receptor subunit 2	0	0	1	1
Gamma-aminobutyric acid type B receptor subunit 2	0	1	0	1
Sodium- and chloride-dependent GABA transporter 1	0	2	0	2
Gamma-aminobutyric acid receptor subunit rho-1	0	0	2	2
Gamma-aminobutyric acid receptor subunit rho-2	0	0	1	1
Sodium- and chloride-dependent GABA transporter 1	0	1	0	1
Sodium- and chloride-dependent taurine transporter	0	1	0	1
Sodium- and chloride-dependent GABA transporter 2	0	2	0	2
Sodium- and chloride-dependent GABA transporter 3	0	2	0	2
Sodium- and chloride-dependent GABA transporter 1	0	1	0	1
Sodium- and chloride-dependent GABA transporter 2	0	2	0	2
Sodium- and chloride-dependent GABA transporter 3	0	2	0	2
Sodium- and chloride-dependent betaine transporter	0	2	0	2
Sodium- and chloride-dependent betaine transporter	0	1	0	1
Sodium- and chloride-dependent GABA transporter 3	0	1	0	1
Histone deacetylase 4	0	3	0	3
4-aminobutyrate aminotransferase, mitochondrial	0	0	0	1
4-aminobutyrate aminotransferase, mitochondrial	0	0	0	1
Histone deacetylase 1	0	3	0	3
Sterol O-acyltransferase 1	0	0	1	1
Proton-coupled amino acid transporter 1	0	2	0	2
Histone deacetylase 7	0	3	0	3
Histone deacetylase 2	0	3	0	3
Polyamine deacetylase HDAC10	0	3	0	3
Histone deacetylase 11	0	3	0	3
Histone deacetylase 8	0	3	0	3
Platelet glycoprotein VI	0	0	1	1
Sodium- and chloride-dependent GABA transporter 2	0	1	0	1
Histone deacetylase 6	0	3	0	3
Gamma-aminobutyric acid type B receptor subunit 1	0	0	1	1
Histone deacetylase 9	0	3	0	3
Histone deacetylase 5	0	3	0	3
Gamma-aminobutyric acid type B receptor subunit 1	0	1	0	1
Glycine receptor subunit alpha-1	0	0	2	2
Sodium- and chloride-dependent glycine transporter 1	0	1	0	1
Large neutral amino acids transporter small subunit 1	0	3	0	4
Serine racemase	0	1	0	1
Olfactory receptor 51E2	0	0	1	1
Sodium- and chloride-dependent glycine transporter 2	0	1	0	1
Purine nucleoside phosphorylase	0	2	0	2
Ricin	0	1	0	1
2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase	0	0	1	1
Purine nucleoside phosphorylase	0	0	1	2
Guanine deaminase	0	1	0	2
Cocaine esterase	0	2	0	2
Voltage-dependent L-type calcium channel subunit alpha-1C	0	3	0	3
UDP-glucuronosyltransferase 1A9	0	1	0	4
Vitamin D-binding protein	0	1	0	1
HLA class I histocompatibility antigen, A alpha chain	0	0	1	1
Integrin beta-1	0	1	0	1
Integrin alpha-4	0	1	0	1
Carbonyl reductase [NADPH] 1	0	0	0	1
C-8 sterol isomerase	0	2	0	2
Kappa-type opioid receptor	0	3	1	5
5-hydroxytryptamine receptor 2A	0	1	0	1
AP-2 complex subunit sigma	0	1	0	1
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase	0	2	0	2
Calcitonin gene-related peptide type 1 receptor	0	1	0	1
Genome polyprotein	0	2	0	2
Sigma intracellular receptor 2	0	1	0	1
Zinc finger protein 664	0	1	0	1
Vesicular acetylcholine transporter	0	1	0	1
Protease	0	2	0	2
Transient receptor potential cation channel subfamily V member 4	0	1	0	1
Transient receptor potential cation channel subfamily V member 2	0	1	0	1
Chain A, HISTIDINE-BINDING PROTEIN	0	0	1	1
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN	0	0	1	1
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN	0	0	1	1
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN	0	0	1	1
Plasma kallikrein	0	0	0	2
Histidine-binding periplasmic protein	0	0	1	1
5-hydroxytryptamine receptor 1D	0	1	0	2
Glutaminyl-peptide cyclotransferase	0	1	0	1
Carbonic anhydrase-like protein, putative	0	0	0	2
UDP-glucuronosyltransferase 1A3	0	0	0	2
Envelope glycoprotein	0	0	3	3
chaperonin-containing TCP-1 beta subunit homolog	1	0	0	1
Synaptic vesicle glycoprotein 2A	0	1	0	1
Mas-related G-protein coupled receptor member X2	0	0	2	2
Aldehyde oxidase 1	0	2	0	2
Nuclear receptor subfamily 1 group I member 2	0	0	2	2
Nuclear receptor subfamily 1 group I member 2	0	0	1	1
UDP-glucuronosyltransferase 1-6	0	1	0	2
UDP-glucuronosyltransferase 1A1	0	1	0	1
UDP-glucuronosyltransferase 2B10	0	1	0	1
Opioid receptor, delta 1b	0	1	0	1
Acetylcholinesterase	0	3	0	4
Opioid receptor homologue	0	1	0	1
Acyl-CoA desaturase 1	0	1	0	1
Histidine decarboxylase	0	0	1	1
Proteinase-activated receptor 1	0	1	1	2
Kappa-type opioid receptor	0	2	1	4
Mu-type opioid receptor	0	2	1	5
Nociceptin receptor	0	1	0	1
Mu-type opioid receptor	0	1	0	1
Mu-type opioid receptor	0	1	0	1
Quinolone resistance protein NorA	0	1	0	1
Aldo-keto reductase family 1 member B1	0	2	0	2
Beta-adrenergic receptor kinase 1	0	1	0	1
Potassium voltage-gated channel subfamily A member 3	0	1	0	1
Substance-P receptor	0	1	0	1
Rhodopsin kinase GRK1	0	1	0	1
G protein-coupled receptor kinase 5	0	1	0	1
G protein-coupled receptor kinase 5	0	1	0	1
P2X purinoceptor 4	0	1	0	1
Rhodopsin kinase GRK1	0	1	0	1
Beta-adrenergic receptor kinase 1	0	0	0	1
apical membrane antigen 1, AMA1	2	0	0	2
ubiquitin-conjugating enzyme E2 N	0	1	0	1
ubiquitin carboxyl-terminal hydrolase 2 isoform a	1	0	0	1
protein AF-9 isoform a	0	0	0	1
bcl-2-related protein A1	0	1	0	1
DNA repair protein RAD52 homolog isoform a	0	0	0	2
Aldehyde oxidase 1	0	1	0	1
Retinal dehydrogenase 1	0	1	0	1
Disintegrin and metalloproteinase domain-containing protein 17	1	0	0	1
Aldehyde oxidase 1	0	1	0	1
Rap guanine nucleotide exchange factor 4	1	0	0	1
Lysine-specific histone demethylase 1A	0	1	0	1
Indoleamine 2,3-dioxygenase 1	0	1	0	1
Amine oxidase [flavin-containing] B	0	2	0	2
Membrane primary amine oxidase	0	1	0	1
Single-stranded DNA cytosine deaminase	1	0	0	1
Chain A, AMINOPEPTIDASE	0	1	0	1
Chain A, AMINOPEPTIDASE	0	1	0	1
Voltage-dependent calcium channel subunit alpha-2/delta-1	0	1	0	1
Alkaline phosphatase, tissue-nonspecific isozyme	0	1	0	1
Alkaline phosphatase, tissue-nonspecific isozyme	0	1	0	1
Intestinal-type alkaline phosphatase	0	1	0	1
Intestinal-type alkaline phosphatase	0	1	0	1
5'-nucleotidase	0	1	0	1
E3 ubiquitin-protein ligase XIAP	0	1	0	1
SLC16A10 protein	0	0	0	1
Large neutral amino acids transporter small subunit 1	0	1	0	1
Monocarboxylate transporter 10	0	0	0	1
Phospholipase A-2-activating protein	0	1	0	1
Estrogen receptor 1	0	1	0	1
Parkin	2	0	0	2
parathyroid hormone/parathyroid hormone-related peptide receptor precursor	2	0	0	2
fMet-Leu-Phe receptor	0	1	0	1
Prostaglandin G/H synthase 2	0	1	0	1
Prostaglandin G/H synthase 1	0	1	0	1
Cyclooxygenase-2	0	1	0	1
Solute carrier family 22 member 8	0	2	0	2
Dihydrofolate reductase	0	1	0	1
hexokinase-4 isoform 1	1	0	0	1
glucokinase regulatory protein	1	0	0	1
Acetylcholinesterase	0	1	0	1
Cholinesterase	0	2	0	2
Acetylcholinesterase	0	1	0	1
Acetylcholinesterase	0	1	0	1
Acetylcholinesterase	0	1	0	1
Cholinesterase	0	1	0	1
Acyl-CoA:cholesterol acyltransferase	0	1	0	1
Carboxylic ester hydrolase	0	1	0	1
Carboxylic ester hydrolase	0	1	0	1
Beta-2 adrenergic receptor	0	1	0	1
Beta-3 adrenergic receptor	0	1	0	1
5-hydroxytryptamine receptor 1B	0	1	0	1
5-hydroxytryptamine receptor 1E	0	1	0	1
luciferase	0	0	0	1
Estrogen receptor	0	2	0	2
Progesterone receptor	0	2	0	3
Glucocorticoid receptor	0	1	1	2
Glucocorticoid receptor	0	0	1	1
Mineralocorticoid receptor	0	2	1	3
Androgen receptor	0	2	0	2
Glutamine synthetase	0	0	1	1
Nociceptin receptor	0	0	1	1
Estrogen receptor beta	0	2	0	2
thioredoxin glutathione reductase	1	0	0	1
Chain A, Ferritin light chain	0	0	1	1
Chain A, Ferritin light chain	0	0	1	1
Chain A, Ferritin light chain	0	0	1	1
Chain A, Ferritin light chain	0	0	1	1
Chain A, Ferritin light chain	0	0	1	1
Chain A, Ferritin light chain	0	0	1	1
Chain A, Ferritin light chain	0	0	1	1
Fatty-acid amide hydrolase 1	0	1	0	1
UDP-glucuronosyltransferase 1A8	0	0	0	1
Solute carrier family 22 member 1	0	1	0	1
Solute carrier organic anion transporter family member 1A4	0	1	0	1
Solute carrier family 22 member 2	0	1	0	1
Histidine-rich protein PFHRP-II	0	1	0	1
Cytochrome P450 2D1	0	1	0	1
Cytochrome P450 2D26	0	1	0	1
Cytochrome P450 2D3	0	1	0	1
Solute carrier organic anion transporter family member 1A1	0	1	0	1
Cytochrome P450 2D4	0	1	0	1
Matrix metalloproteinase-9	0	1	0	1
Rap guanine nucleotide exchange factor 3	2	0	0	2
Transcriptional activator protein LuxR	0	1	0	1
3-oxo-5-alpha-steroid 4-dehydrogenase 2	0	1	0	1
PINK1	1	0	0	1
photoreceptor-specific nuclear receptor	0	1	0	1
serine/threonine-protein kinase PLK1	1	0	0	1
transactivating tegument protein VP16 [Human herpesvirus 1]	0	1	0	1
3-hydroxy-3-methylglutaryl-coenzyme A reductase	0	2	0	2
Insulin receptor	0	1	0	1
Nuclear receptor subfamily 4 group A member 2	0	0	1	1
3-hydroxy-3-methylglutaryl-coenzyme A reductase	0	1	0	1
Solute carrier organic anion transporter family member 1B1	0	2	0	2
Cytochrome P450 3A5	0	1	0	1
Peptidyl-prolyl cis-trans isomerase FKBP1A	0	2	1	3
Peptidyl-prolyl cis-trans isomerase FKBP1B	0	0	1	1
Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform	0	1	0	1
Peptidyl-prolyl cis-trans isomerase FKBP5	0	1	0	1
Splicing factor 3B subunit 3	0	1	0	1
Broad substrate specificity ATP-binding cassette transporter ABCG2	0	1	0	1
Chain A, ykoF	0	0	1	1
Chain B, ykoF	0	0	1	1
Chain A, ThiT	0	0	1	1
Thiamine transporter ThiT	0	0	1	1
Transketolase	0	0	1	1
Thiamine-binding periplasmic protein	0	0	1	1
Genome polyprotein	0	1	0	1
Ubiquitin carboxyl-terminal hydrolase 1	0	1	0	1
Lysozyme C-1	0	1	0	1
Glycoprotein hormones alpha chain	1	0	0	1
Protein kinase C alpha type	0	1	0	1
Beta-glucuronidase	0	1	0	1
Protein kinase C delta type	0	1	0	1
Protein kinase C epsilon type	0	1	0	1
Protein kinase C zeta type	0	1	0	1
Guanine nucleotide-binding protein G	1	0	0	1
Protein kinase C gamma type	0	1	0	1
Protein kinase C beta type	0	1	0	1
DNA-dependent protein kinase catalytic subunit	0	1	0	1
Protein kinase C eta type	0	1	0	1
Calcium-dependent protein kinase 4	0	1	0	1
WD repeat-containing protein 48	0	1	0	1
Emopamil-binding protein-like	0	1	0	1
Protein kinase C theta type	0	1	0	1
Chain A, Glycogen phosphorylase, liver form	0	0	1	1
Chain A, glycogen phosphorylase, liver form	0	0	1	1
Chain A, Glycogen phosphorylase, liver form	0	0	1	1
Chain A, Glycogen phosphorylase, liver form	0	0	1	1
Solute carrier family 22 member 6	0	0	0	1
Solute carrier family 2, facilitated glucose transporter member 9	0	1	1	2
Tissue factor	0	1	0	1
Aldo-keto reductase family 1 member A1	0	1	0	1
Aldo-keto reductase family 1 member A1	0	1	0	1
Aldo-keto reductase family 1 member A1	0	1	0	1
Aldo-keto reductase family 1 member B7	0	1	0	1
NAD-dependent protein deacylase sirtuin-5, mitochondrial	0	1	0	1
Amine oxidase [flavin-containing]	0	1	0	1
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Synonyms(9)

Research Excerpts

Overview

Treatment

Research

Studies (145)

Protein Targets (1,234)

Kussmaul Aphasia

Synonyms(9)

Research Excerpts

Overview

Treatment

Research

Studies (145)

Drugs Studied (113)

Protein Targets (1,234)