Page last updated: 2024-08-05 13:28:11

mastoparans

A group of cytoactive tetradecapeptide found in wasp venoms. They cause the degranulation of mast cells.

ChEBI ID: 78506

Members (2)

MemberDefinitionRole
mastoparanA member of the class of mastopyrans that is a 14-amino acid polypeptide comprising isoleucyl, asparaginyl, leucyl, lysyl, alanyl, leucyl, alanyl, alanyl, leucyl, alanyl, lysyl, lysyl, isoleucyl, and leucinamide residues coupled in sequence. It is the major active component of the venom of the vespid wasp, Vespula lewisii and causes degranulation of mast cells.mastoparan
mastoparan xA member of the class of mastopyrans that is a 14-amino acid polypeptide comprising isoleucyl, asparaginyl, tryptophyl, lysyl, glycyl, isoleucyl, alanyl, alanyl, methionyl, alanyl, lysyl, lysyl, leucyl, and leucinamide residues coupled in sequence. It is the major active component of the venom of the hornet Vespa velutina and causes degranulation of mast cells. It exhibits antimicrobial activity against both Gram-positive and -negative bacteria as well as haemolytic activity on chicken, human and sheep erythrocytes.mastoparan-V

Research

Studies (573)

TimeframeStudies, Drugs in This Class (%)All Drugs %
pre-199036 (6.28)18.7374
1990's280 (48.87)18.2507
2000's163 (28.45)29.6817
2010's79 (13.79)24.3611
2020's15 (2.62)2.80

Study Types

Publication TypeStudies, Drugs in This Class (%)All Drugs (%)
Trials1 (0.17%)5.53%
Reviews25 (4.20%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other569 (95.63%)84.16%