| Member | Definition | Role |
|---|
| latrunculin a | A bicyclic macrolide natural product consisting of a 16-membered bicyclic lactone attached to the rare 2-thiazolidinone moiety. It is obtained from the Red Sea sponge Latrunculia magnifica and from the Fiji Islands sponge Cacospongia mycofijiensis. Latrunculin A inhibits actin polymerisation, microfilament organsation and microfilament-mediated processes. | latrunculin A |
| latrunculin b | A macrolide consisting of a 14-membered bicyclic lactone attached to the rare 2-thiazolidinone moiety. It is obtained from the Red Sea sponge Latrunculia magnifica. | latrunculin B |
| squalestatin 1 | A polyketide isolated from fungi that is a potent inhibitor of fungal and mammalian squalene synthase. | zaragozic acid A |
| zaragozic acid c | A polyketide isolated from fungi that is a potent inhibitor of fungal and mammalian squalene synthase. | zaragozic acid C |