Page last updated: 2024-08-05 13:03:10
oxabicycloalkane
null
ChEBI ID: 46733
Members (4)
| Member | Definition | Role |
|---|---|---|
| latrunculin a | A bicyclic macrolide natural product consisting of a 16-membered bicyclic lactone attached to the rare 2-thiazolidinone moiety. It is obtained from the Red Sea sponge Latrunculia magnifica and from the Fiji Islands sponge Cacospongia mycofijiensis. Latrunculin A inhibits actin polymerisation, microfilament organsation and microfilament-mediated processes. | latrunculin A |
| latrunculin b | A macrolide consisting of a 14-membered bicyclic lactone attached to the rare 2-thiazolidinone moiety. It is obtained from the Red Sea sponge Latrunculia magnifica. | latrunculin B |
| squalestatin 1 | A polyketide isolated from fungi that is a potent inhibitor of fungal and mammalian squalene synthase. | zaragozic acid A |
| zaragozic acid c | A polyketide isolated from fungi that is a potent inhibitor of fungal and mammalian squalene synthase. | zaragozic acid C |
Research
Studies (1,179)
| Timeframe | Studies, Drugs in This Class (%) | All Drugs % |
|---|---|---|
| pre-1990 | 7 (0.59) | 18.7374 |
| 1990's | 110 (9.33) | 18.2507 |
| 2000's | 626 (53.10) | 29.6817 |
| 2010's | 405 (34.35) | 24.3611 |
| 2020's | 31 (2.63) | 2.80 |
Study Types
| Publication Type | Studies, Drugs in This Class (%) | All Drugs (%) |
|---|---|---|
| Trials | 0 (0.00%) | 5.53% |
| Reviews | 14 (1.14%) | 6.00% |
| Case Studies | 1 (0.08%) | 4.05% |
| Observational | 0 (0.00%) | 0.25% |
| Other | 1,214 (98.78%) | 84.16% |