Acute Porphyria

Synonym
Acute Porphyria
Hydroxymethylbilane Synthase Deficiency
PBGD Deficiency
Porphobilinogen Deaminase Deficiency
Porphyria, Swedish Type
UPS Deficiency
Uroporphyrinogen Synthase Deficiency

Timeframe	Studies, This Condition (%)	All Conditions %
pre-1990	84 (19.22)	23.3326
1990's	79 (18.08)	12.5806
2000's	99 (22.65)	18.1394
2010's	95 (21.74)	28.8240
2020's	53 (12.13)	9.53

Drug	Studies	First Year	Last Year	Average Age	Relationship Strength	Trials	pre-1990	1990's	2000's	2010's	post-2020
gamma-aminobutyric acid	8	1995	2013	20.5	low	0	0	4	3	1	0
aminolevulinic acid	76	1955	2023	19.1	high	6	5	17	30	17	7
acetone	1	1963	1963	61.0	low	0	1	0	0	0	0
adenine	1	1996	1996	28.0	low	0	0	1	0	0	0
aminoacetone	1	1963	1963	61.0	low	0	1	0	0	0	0
chlorine	1	1949	1949	75.0	low	0	1	0	0	0	0
salicylic acid	1	1993	1993	31.0	low	0	0	1	0	0	0
creatine	1	1965	1965	59.0	low	0	1	0	0	0	0
cytosine	2	1993	1994	30.5	low	0	0	2	0	0	0
formaldehyde	1	1996	1996	28.0	low	0	0	1	0	0	0
glycine	4	1961	2015	48.0	low	0	3	0	0	1	0
hydrogen	1	2014	2014	10.0	low	0	0	0	0	1	0
hydroxymethylbilane	1	2005	2005	19.0	low	0	0	0	1	0	0
indole	1	1957	1957	67.0	low	0	1	0	0	0	0
iodine	2	1963	1964	60.5	low	0	2	0	0	0	0
kynurenine	2	2017	2022	4.5	low	0	0	0	0	1	1
melatonin	5	1993	2013	22.6	low	0	0	3	1	1	0
nitrous oxide	2	2004	2007	18.5	low	0	0	0	2	0	0
oxalic acid	2	2010	2011	13.5	low	0	0	0	1	1	0
porphobilinogen	115	1945	2023	21.5	high	6	18	17	31	41	8
pyridoxal phosphate	2	2010	2021	8.5	low	0	0	0	1	0	1
pyridoxine	1	2011	2011	13.0	low	0	0	0	0	1	0
succinic acid	1	2022	2022	2.0	low	0	0	0	0	0	1
uroporphyrinogen iii	2	2004	2005	19.5	low	0	0	0	2	0	0
1-anilino-8-naphthalenesulfonate	1	1996	1996	28.0	low	0	0	1	0	0	0
phenytoin	2	1963	2008	38.5	low	0	1	0	1	0	0
amlodipine	3	1997	2007	23.7	low	0	0	2	1	0	0
anastrozole	1	2008	2008	16.0	low	0	0	0	1	0	0
azathioprine	1	2003	2003	21.0	low	0	0	0	1	0	0
barbital	2	2005	2007	18.0	low	0	0	0	2	0	0
benserazide	1	1995	1995	29.0	low	0	0	1	0	0	0
benzocaine	1	2007	2007	17.0	low	0	0	0	1	0	0
bupivacaine	2	2007	2014	13.5	low	0	0	0	1	1	0
carbamazepine	1	2001	2001	23.0	low	0	0	0	1	0	0
chlorambucil	1	2002	2002	22.0	low	0	0	0	1	0	0
chloroquine	4	1957	2002	35.5	low	0	1	2	1	0	0
chlorpromazine	12	1955	1999	51.8	low	0	8	4	0	0	0
cimetidine	5	1993	2005	25.6	low	0	0	3	2	0	0
clonazepam	1	1997	1997	27.0	low	0	0	1	0	0	0
clonidine	1	1997	1997	27.0	low	0	0	1	0	0	0
deferiprone	1	2020	2020	4.0	low	0	0	0	0	1	0
deferoxamine	1	1993	1993	31.0	low	0	0	1	0	0	0
deferoxamine	1	1993	1993	31.0	low	0	0	1	0	0	0
amphetamine	1	1996	1996	28.0	low	0	0	1	0	0	0
diazepam	3	1999	2008	21.7	low	0	0	2	1	0	0
pentetic acid	1	1994	1994	30.0	low	0	0	1	0	0	0
dimercaprol	4	1956	1964	65.2	low	0	4	0	0	0	0
valproic acid	2	1997	2012	19.5	low	0	0	1	0	1	0
doxazosin	1	1997	1997	27.0	low	0	0	1	0	0	0
enflurane	1	2005	2005	19.0	low	0	0	0	1	0	0
ether	1	1962	1962	62.0	low	0	1	0	0	0	0
fentanyl	1	1999	1999	25.0	low	0	0	1	0	0	0
fluconazole	1	2019	2019	5.0	low	0	0	0	0	1	0
gabapentin	7	1995	2013	19.4	low	0	0	3	3	1	0
haloperidol	2	1995	2003	25.0	low	0	0	1	1	0	0
halothane	2	1964	2002	41.0	low	0	1	0	1	0	0
hydroxychloroquine	1	2020	2020	4.0	low	0	0	0	0	1	0
imipramine	1	1999	1999	25.0	low	0	0	1	0	0	0
isoflurane	3	1992	2005	23.7	low	0	0	1	2	0	0
isoproterenol	1	1996	1996	28.0	low	0	0	1	0	0	0
ketamine	1	1997	1997	27.0	low	0	0	1	0	0	0
labetalol	1	2019	2019	5.0	low	0	0	0	0	1	0
lamotrigine	1	1996	1996	28.0	low	0	0	1	0	0	0
letrozole	1	2008	2008	16.0	low	0	0	0	1	0	0
meperidine	2	1995	1999	27.0	low	0	0	2	0	0	0
methenamine	1	2010	2010	14.0	low	0	0	0	1	0	0
metoclopramide	2	1997	1997	27.0	low	0	0	2	0	0	0
mitotane	1	2011	2011	13.0	low	0	0	0	0	1	0
neostigmine	1	1953	1953	71.0	low	0	1	0	0	0	0
nevirapine	1	2010	2010	14.0	low	0	0	0	1	0	0
perphenazine	1	1998	1998	26.0	low	0	0	1	0	0	0
phenazopyridine	1	1952	1952	72.0	low	0	1	0	0	0	0
phenobarbital	14	1963	2019	18.6	low	0	1	3	4	6	0
piracetam	1	2008	2008	16.0	low	0	0	0	1	0	0
pirenzepine	1	2003	2003	21.0	low	0	0	0	1	0	0
procaine	1	1953	1953	71.0	low	0	1	0	0	0	0
prochlorperazine	1	1964	1964	60.0	low	0	1	0	0	0	0
promethazine	3	1964	2008	33.7	low	0	1	1	1	0	0
propofol	9	1992	2014	25.8	low	0	0	7	1	1	0
propranolol	2	1978	2008	31.0	low	0	1	0	1	0	0
sevoflurane	5	2001	2006	20.4	low	0	0	0	5	0	0
succinylacetone	1	1996	1996	28.0	low	0	0	1	0	0	0
succinylcholine	2	1964	2008	38.0	low	0	1	0	1	0	0
tetraethylammonium	1	1952	1952	72.0	low	0	1	0	0	0	0
trifluoperazine	1	1959	1959	65.0	low	0	1	0	0	0	0
trihexyphenidyl	1	1995	1995	29.0	low	0	0	1	0	0	0
corticosterone	1	2011	2011	13.0	low	0	0	0	0	1	0
prednisolone	1	2003	2003	21.0	low	0	0	0	1	0	0
sorbitol	1	1964	1964	60.0	low	0	1	0	0	0	0
thyroxine	1	1963	1963	61.0	low	0	1	0	0	0	0
tetrahydrocortisol	1	2013	2013	11.0	low	0	0	0	0	1	0
prednisone	1	1964	1964	60.0	low	0	1	0	0	0	0
androsterone	1	2013	2013	11.0	low	0	0	0	0	1	0
etiocholanolone	1	2013	2013	11.0	low	0	0	0	0	1	0
ethinyl estradiol	3	1964	1965	59.7	low	0	3	0	0	0	0
aminopyrine	1	1995	1995	29.0	low	0	0	1	0	0	0
galactose	1	2004	2004	20.0	low	0	0	0	1	0	0
phenylephrine	1	2019	2019	5.0	low	0	0	0	0	1	0
levodopa	1	1995	1995	29.0	low	0	0	1	0	0	0
edetic acid	4	1957	1964	63.0	low	0	4	0	0	0	0
tyrosine	1	1965	1965	59.0	low	0	1	0	0	0	0
androstenedione	1	1979	1979	45.0	low	0	1	0	0	0	0
methionine	2	2000	2021	13.5	low	0	0	1	0	0	1
cycloheximide	1	2008	2008	16.0	low	0	0	0	1	0	0
barbituric acid	2	1964	1964	60.0	low	0	2	0	0	0	0
norethindrone	1	1965	1965	59.0	low	0	1	0	0	0	0
norethynodrel	1	1965	1965	59.0	low	0	1	0	0	0	0
histidine	1	1993	1993	31.0	low	0	0	1	0	0	0
medroxyprogesterone acetate	1	2019	2019	5.0	low	0	0	0	0	1	0
threonine	1	2000	2000	24.0	low	0	0	1	0	0	0
mestranol	1	1964	1964	60.0	low	0	1	0	0	0	0
tryptophan	5	1965	2022	25.4	low	0	1	2	0	1	1
arginine	34	1993	2021	17.7	medium	2	0	6	19	7	2
thymol	1	1963	1963	61.0	low	0	1	0	0	0	0
4-(dimethylamino)benzaldehyde	1	2003	2003	21.0	low	0	0	0	1	0	0
pyrroles	8	1961	2020	46.5	low	0	6	0	0	2	0
dydrogesterone	1	2020	2020	4.0	low	0	0	0	0	1	0
pyrazines	1	2002	2002	22.0	low	0	0	0	1	0	0
allylisopropylacetamide	5	1995	2013	20.6	low	0	0	2	2	1	0
kynuramine	1	2005	2005	19.0	low	0	0	0	1	0	0
medroxyprogesterone	2	1964	1965	59.5	low	0	2	0	0	0	0
apiole	1	1954	1954	70.0	low	0	1	0	0	0	0
chlorotrianisene	1	1965	1965	59.0	low	0	1	0	0	0	0
levulinic acid	5	1963	1965	60.0	low	0	5	0	0	0	0
dicarbethoxydihydrocollidine	3	1997	2013	19.0	low	0	0	1	1	1	0
d-alpha tocopherol	1	1995	1995	29.0	low	0	0	1	0	0	0
metylperon	1	2018	2018	6.0	low	0	0	0	0	1	0
azo rubin s	1	1951	1951	73.0	low	0	1	0	0	0	0
methenamine hippurate	1	2010	2010	14.0	low	0	0	0	1	0	0
manganese	2	1997	1997	27.0	low	0	0	2	0	0	0
cadmium	1	2012	2012	12.0	low	0	0	0	0	1	0
tricalcium phosphate	1	1951	1951	73.0	low	0	1	0	0	0	0
trolamine salicylate	1	1964	1964	60.0	low	0	1	0	0	0	0
urobilinogen	1	2003	2003	21.0	low	0	0	0	1	0	0
phenyl acetate	3	1995	2000	26.3	low	0	0	3	0	0	0
pregnanolone	1	2012	2012	12.0	low	0	0	0	0	1	0
acetylgalactosamine	19	2019	2023	3.3	low	5	0	0	0	9	10
desogestrel	1	2006	2006	18.0	low	0	0	0	1	0	0
desflurane	1	2004	2004	20.0	low	0	0	0	1	0	0
pergolide	1	1997	1997	27.0	low	0	0	1	0	0	0
buserelin	1	1992	1992	32.0	low	0	0	1	0	0	0
alfentanil	1	1993	1993	31.0	low	0	0	1	0	0	0
remifentanil	1	2002	2002	22.0	low	0	0	0	1	0	0
3-iodobenzylguanidine	1	2011	2011	13.0	low	0	0	0	0	1	0
adenosine	1	1963	1963	61.0	low	0	1	0	0	0	0
vanadates	1	2012	2012	12.0	low	0	0	0	0	1	0
efavirenz	1	2015	2015	9.0	low	0	0	0	0	1	0
oseltamivir	1	2022	2022	2.0	low	0	0	0	0	0	1
glutathione disulfide	1	2013	2013	11.0	low	0	0	0	0	1	0
triazoles	3	2004	2008	17.7	low	0	0	0	3	0	0
coproporphyrin i	2	1999	2009	20.0	low	1	0	1	1	0	0
voriconazole	2	2004	2007	18.5	low	0	0	0	2	0	0
uroporphyrin iii	2	1953	2015	40.0	low	0	1	0	0	1	0
uroporphyrin i	2	1946	2009	46.5	low	0	1	0	1	0	0
homocysteine	5	2020	2021	3.2	low	0	0	0	0	1	4
allotetrahydrocortisol	1	2013	2013	11.0	low	0	0	0	0	1	0
cobalt	1	1963	1963	61.0	low	0	1	0	0	0	0
vitamin b 6	1	2010	2010	14.0	low	0	0	0	1	0	0
cobaltiprotoporphyrin	1	2008	2008	16.0	low	0	0	0	1	0	0
valerates	2	1998	2002	24.0	low	0	0	1	1	0	0
zinc coproporphyrin iii	1	1999	1999	25.0	low	1	0	1	0	0	0
4,5-dioxovaleric acid	2	1998	2002	24.0	low	0	0	1	1	0	0
methotrexate	1	2016	2016	8.0	low	0	0	0	0	1	0
docetaxel anhydrous	1	2008	2008	16.0	low	0	0	0	1	0	0
atazanavir sulfate	1	2016	2016	8.0	low	0	0	0	0	1	0
zinc hematoporphyrin	1	1962	1962	62.0	low	0	1	0	0	0	0
cortisone	3	1951	1957	71.0	low	0	3	0	0	0	0
ritonavir	1	2016	2016	8.0	low	0	0	0	0	1	0
oxytocin	1	2011	2011	13.0	low	0	0	0	0	1	0
griseofulvin	4	1964	2007	38.8	low	0	2	0	2	0	0
rocuronium	1	2006	2006	18.0	low	0	0	0	1	0	0
tibolone	1	2001	2001	23.0	low	0	0	0	1	0	0
resveratrol	1	2005	2005	19.0	low	0	0	0	1	0	0
retinol	1	1963	1963	61.0	low	0	1	0	0	0	0
tacrolimus	2	2001	2001	23.0	low	0	0	0	2	0	0
mycophenolic acid	1	2003	2003	21.0	low	0	0	0	1	0	0
diethylstilbestrol	1	1965	1965	59.0	low	0	1	0	0	0	0
dactinomycin	2	2008	2016	12.0	low	0	0	0	1	1	0
dipyrone	1	2019	2019	5.0	low	0	0	0	0	1	0
stilbenes	1	2005	2005	19.0	low	0	0	0	1	0	0
buprenorphine	1	1993	1993	31.0	low	0	0	1	0	0	0
enclomiphene	1	2006	2006	18.0	low	0	0	0	1	0	0
nadp	1	2013	2013	11.0	low	0	0	0	0	1	0
thiopental	2	1964	2002	41.0	low	0	1	0	1	0	0
quercetin	1	2005	2005	19.0	low	0	0	0	1	0	0
vitamin k semiquinone radical	1	1963	1963	61.0	low	0	1	0	0	0	0
beta carotene	1	2002	2002	22.0	low	0	0	0	1	0	0
isotretinoin	1	2007	2007	17.0	low	0	0	0	1	0	0
misoprostol	1	2006	2006	18.0	low	0	0	0	1	0	0
levetiracetam	1	2008	2008	16.0	low	0	0	0	1	0	0
sirolimus	1	2002	2002	22.0	low	0	0	0	1	0	0
morphine	2	2001	2010	18.5	low	0	0	0	2	0	0
lead	3	1999	2021	15.3	low	0	0	1	1	0	1
indolylacryloylglycine	1	2015	2015	9.0	low	0	0	0	0	1	0
monocrotophos	1	2022	2022	2.0	low	0	0	0	0	0	1
thyronines	1	1963	1963	61.0	low	0	1	0	0	0	0
clasto-lactacystin beta-lactone	1	2006	2006	18.0	low	0	0	0	1	0	0
eslicarbazepine	1	2020	2020	4.0	low	0	0	0	0	1	0
losartan potassium	2	2002	2008	19.0	low	0	0	0	2	0	0
pituitrin	7	1962	2023	39.3	low	0	4	1	0	1	1
cytochrome c-t	1	1961	1961	63.0	low	0	1	0	0	0	0
glucagon	1	2016	2016	8.0	low	0	0	0	0	1	0
oligonucleotides	1	1994	1994	30.0	low	0	0	1	0	0	0
c-peptide	1	2017	2017	7.0	low	0	0	0	0	1	0
phosphatidylcholines	1	1963	1963	61.0	low	0	1	0	0	0	0
chlorophyll a	2	1963	1963	61.0	low	0	2	0	0	0	0
quetiapine fumarate	1	2017	2017	7.0	low	0	0	0	0	1	0
trelstar	1	1999	1999	25.0	low	0	0	1	0	0	0
nafarelin	1	2000	2000	24.0	low	0	0	1	0	0	0
piperidines	1	2002	2002	22.0	low	0	0	0	1	0	0
heme	103	1964	2023	16.3	high	3	8	16	31	34	14
epoetin alfa	1	2008	2008	16.0	low	0	0	0	1	0	0
vitamin b 12	6	1963	2021	33.8	low	0	3	0	1	1	1
cyclosporine	4	2001	2006	21.2	low	0	0	0	4	0	0
deoxyguanosine	2	1994	2002	26.0	low	0	0	1	1	0	0
guanine	3	1993	1998	28.3	low	0	0	3	0	0	0
inosine diphosphate	1	2003	2003	21.0	low	0	0	0	1	0	0
folic acid	3	2010	2021	6.7	low	0	0	0	1	0	2
olanzapine	1	2003	2003	21.0	low	0	0	0	1	0	0
8-hydroxy-2'-deoxyguanosine	2	1994	2002	26.0	low	0	0	1	1	0	0
heme arginate	32	1993	2021	17.2	high	2	0	5	18	7	2

Treatment of neuropathic pain in acute intermittent porphyria with gabapentin.
Journal of the Formosan Medical Association = Taiwan yi zhi, , Volume: 112, Issue:9, 2013

Gabapentin reduces neurovisceral pain of porphyria.
Acta neurologica Taiwanica, , Volume: 19, Issue:2, 2010

Use of propofol anesthesia and adjunctive treatment with levetiracetam and gabapentin in managing status epilepticus in a patient of acute intermittent porphyria.
Epilepsia, , Volume: 49, Issue:5, 2008

Drug use in porphyria: a therapeutic dilemma.
Singapore medical journal, , Volume: 49, Issue:10, 2008

Gabapentin in seizures due to acute intermittent porphyria.
Neurology India, , Volume: 48, Issue:2, 2000

Treatment of seizures in acute intermittent porphyria: safety and efficacy of gabapentin.
Seizure, , Volume: 7, Issue:5, 1998

Increased delta aminolevulinic acid and decreased pineal melatonin production. A common event in acute porphyria studies in the rat.
The Journal of clinical investigation, , Jan-01, Volume: 97, Issue:1, 1996

Gabapentin treatment of seizures in acute intermittent porphyria.
Neurology, , Volume: 45, Issue:6, 1995

Acute intermittent porphyria presenting with neurological emergency: review of six cases.
Neurology India, , Volume: 55, Issue:4

Gabapentin and propofol for treatment of status epilepticus in acute intermittent porphyria.
Journal of postgraduate medicine, , Volume: 49, Issue:3

AMINOACETONE IN ACUTE INTERMITTENT PORPHYRIA.
Lancet (London, England), , Sep-28, Volume: 2, Issue:7309, 1963

The dual face of endogenous alpha-aminoketones: pro-oxidizing metabolic weapons.
Comparative biochemistry and physiology. Toxicology & pharmacology : CBP, , Volume: 146, Issue:1-2

Hepatocellular carcinoma in patients from northern Sweden with acute intermittent porphyria: morphology and mutations.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, , Volume: 5, Issue:5, 1996

AMINOACETONE IN ACUTE INTERMITTENT PORPHYRIA.
Lancet (London, England), , Sep-28, Volume: 2, Issue:7309, 1963

The dual face of endogenous alpha-aminoketones: pro-oxidizing metabolic weapons.
Comparative biochemistry and physiology. Toxicology & pharmacology : CBP, , Volume: 146, Issue:1-2

SODIUM AND CHLORIDE DEPLETION IN ACUTE PORPHYRIA WITH REFERENCE TO THE STATUS OF ADRENAL CORTICAL FUNCTION.
The Journal of clinical investigation, , Volume: 28, Issue:4, 1949

Anaesthesia for the porphyric patient.
Anaesthesia, , Volume: 48, Issue:11, 1993

RENAL MECHANISM FOR EXCRETION OF PORPHYRIN PRECURSORS IN PATIENTS WITH ACUTE INTERMITTENT PORPHYRIA AND CHRONIC LEAD POISONING.
Blood, , Volume: 26, 1965

Acute intermittent porphyria caused by a single base insertion of C in exon 15 of the porphobilinogen deaminase gene that results in a frame shift and premature stopping of translation.
Human genetics, , Volume: 93, Issue:5, 1994

Acute intermittent porphyria caused by a G to C mutation in exon 12 of the porphobilinogen deaminase gene that results in exon skipping.
Human genetics, , Volume: 92, Issue:6, 1993

Hepatocellular carcinoma in patients from northern Sweden with acute intermittent porphyria: morphology and mutations.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, , Volume: 5, Issue:5, 1996

Mass spectrometric characterisation of a condensation product between porphobilinogen and indolyl-3-acryloylglycine in urine of patients with acute intermittent porphyria.
Journal of mass spectrometry : JMS, , Volume: 50, Issue:7, 2015

[THE GLYCINE TOLERANCE TEST IN THE COURSE OF ACUTE INTERMITTENT PORPHYRIA].
Bulletins et memoires de la Societe medicale des hopitaux de Paris, , Nov-13, Volume: 115, 1964

ACUTE INTERMITTENT PORPHYRIA IN A CHILD WITH A NOTE ON THE GLYCINE LOADING TEST.
Pediatrics, , Volume: 34, 1964

Glycine metabolism in acute porphyria.
Clinical science, , Volume: 20, 1961

[Acute idiopathic porphyria with abdominal onset; neurological syndrome appearing after surgery; therapy with glycocoll & edathamil calcium].
Bulletins et memoires de la Societe medicale des hopitaux de Paris, , Volume: 75, Issue:9-11

Urinary metabolic fingerprint of acute intermittent porphyria analyzed by (1)H NMR spectroscopy.
Analytical chemistry, , Feb-18, Volume: 86, Issue:4, 2014

Gene symbol: HMBS. Disease: Porphyria, acute intermittent.
Human genetics, , Volume: 116, Issue:6, 2005

Excessive constipation with indoluria simulating acute porphyria.
Acta medica Scandinavica, , Aug-13, Volume: 158, Issue:2, 1957

SERUM PROTEIN-BOUND IODINE IN ACUTE INTERMITTENT PORPHYRIA.
The Journal of clinical endocrinology and metabolism, , Volume: 24, 1964

ELEVATION OF THE SERUM PROTEIN-BOUND IODINE IN ACUTE INTERMITTENT PORPHYRIA.
The Journal of clinical endocrinology and metabolism, , Volume: 23, 1963

Evaluation of Metabolic Changes in Acute Intermittent Porphyria Patients by Targeted Metabolomics.
International journal of molecular sciences, , Mar-16, Volume: 23, Issue:6, 2022

Comprehensive analysis of the tryptophan metabolome in urine of patients with acute intermittent porphyria.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, , Aug-15, Volume: 1060, 2017

Circadian rhythms in acute intermittent porphyria--a pilot study.
European journal of clinical investigation, , Volume: 43, Issue:7, 2013

Inhibition of 5-aminolevulinic acid-induced DNA damage by melatonin, N1-acetyl-N2-formyl-5-methoxykynuramine, quercetin or resveratrol.
Journal of pineal research, , Volume: 38, Issue:2, 2005

Melatonin and epileptic seizures in patients with acute intermittent porphyria.
Epileptic disorders : international epilepsy journal with videotape, , Volume: 2, Issue:4, 2000

Increased delta aminolevulinic acid and decreased pineal melatonin production. A common event in acute porphyria studies in the rat.
The Journal of clinical investigation, , Jan-01, Volume: 97, Issue:1, 1996

Decreased nocturnal plasma melatonin levels in patients with recurrent acute intermittent porphyria attacks.
Life sciences, , Volume: 53, Issue:8, 1993

The dental management of five paediatric patients with a history of acute intermittent porphyria.
European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry, , Volume: 8, Issue:4, 2007

Pro-oxidant and antioxidant factors in acute intermittent porphyria: family studies.
Journal of inherited metabolic disease, , Volume: 27, Issue:2, 2004

Kidney damage in acute intermittent porphyria.
Przeglad lekarski, , Volume: 68, Issue:9, 2011

Vitamin B6 and oxalic acid in clinical nephrology.
Journal of renal nutrition : the official journal of the Council on Renal Nutrition of the National Kidney Foundation, , Volume: 20, Issue:5 Suppl, 2010

Dysregulation of homocysteine homeostasis in acute intermittent porphyria patients receiving heme arginate or givosiran.
Journal of inherited metabolic disease, , Volume: 44, Issue:4, 2021

Preliminary report: hyperhomocysteinemia in patients with acute intermittent porphyria.
Metabolism: clinical and experimental, , Volume: 59, Issue:12, 2010

Kidney damage in acute intermittent porphyria.
Przeglad lekarski, , Volume: 68, Issue:9, 2011

Evaluation of Metabolic Changes in Acute Intermittent Porphyria Patients by Targeted Metabolomics.
International journal of molecular sciences, , Mar-16, Volume: 23, Issue:6, 2022

Gene symbol: HMBS. Disease: Porphyria, acute intermittent.
Human genetics, , Volume: 116, Issue:6, 2005

Liver transplantation as a cure for acute intermittent porphyria.
Lancet (London, England), , Feb-28, Volume: 363, Issue:9410, 2004

[High lipase level in a patient with porphyria crisis: cause of confusion with acute pancreatitis].
Revista medica de Chile, , Volume: 124, Issue:10, 1996

Drug use in porphyria: a therapeutic dilemma.
Singapore medical journal, , Volume: 49, Issue:10, 2008

THE EFFECT OF DIPHENYLHYDANTOIN (DILANTIN) ON ACUTE INTERMITTENT PORPHYRIA.
Transactions of the American Neurological Association, , Volume: 88, 1963

Acute intermittent porphyria: diagnosis per chance.
Indian journal of pathology & microbiology, , Volume: 51, Issue:4

Safety of amlodipine use in patients with acute intermittent porphyria.
British journal of clinical pharmacology, , Volume: 64, Issue:2, 2007

Drug treatment of hypertension in acute intermittent porphyria: doxazosin and amlodipine.
British journal of clinical pharmacology, , Volume: 43, Issue:3, 1997

Amlodipine-induced acute intermittent porphyria exacerbation.
The Annals of pharmacotherapy, , Volume: 31, Issue:2, 1997

Anticancer therapy in patients with porphyrias: evidence today.
Expert opinion on drug safety, , Volume: 7, Issue:2, 2008

Renal transplantation in a case of acute intermittent porphyria.
Journal of clinical pharmacology, , Volume: 43, Issue:10, 2003

Metabolization of porphyrinogenic agents in brain: involvement of the phase I drug metabolizing system. A comparative study in liver and kidney.
Cellular and molecular neurobiology, , Volume: 27, Issue:6, 2007

Heme oxygenase, aminolevulinate acid synthetase and the antioxidant system in the brain of mice treated with porphyrinogenic drugs.
Cellular and molecular biology (Noisy-le-Grand, France), , Oct-03, Volume: 51, Issue:5, 2005

Treatment of Parkinson's disease in a patient with acute intermittent porphyria.
British journal of clinical pharmacology, , Volume: 40, Issue:1, 1995

The dental management of five paediatric patients with a history of acute intermittent porphyria.
European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry, , Volume: 8, Issue:4, 2007

Safe usage of bicalutamide and goserelin in a male patient with acute intermittent porphyria and prostate cancer.
Scandinavian journal of urology, , Volume: 53, Issue:2-3

Ultrasound-guided regional anesthesia in a pediatric patient with acute intermittent porphyria: literature review and case report.
Middle East journal of anaesthesiology, , Volume: 22, Issue:5, 2014

The dental management of five paediatric patients with a history of acute intermittent porphyria.
European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry, , Volume: 8, Issue:4, 2007

Acute intermittent porphyria, seizures, and antiepileptic drugs: a report on a 3-year-old Nigerian boy.
Seizure, , Volume: 10, Issue:1, 2001

Chlorambucil and acute intermittent porphyria.
Clinical oncology (Royal College of Radiologists (Great Britain)), , Volume: 14, Issue:6, 2002

Management of acute and cutaneous porphyrias.
International journal of clinical practice, , Volume: 56, Issue:4, 2002

[Hepatic porphyria].
La Revue de medecine interne, , Volume: 20, Issue:4, 1999

Precipitation of acute intermittent porphyria by chloroquin.
Indian pediatrics, , Volume: 33, Issue:3, 1996

Acute porphyria and coproporphyrinuria following chloroquine therapy; a report of two cases.
A.M.A. archives of dermatology, , Volume: 75, Issue:6, 1957

The effect of therapeutic drugs and other pharmacologic agents on activity of porphobilinogen deaminase, the enzyme that is deficient in intermittent acute porphyria.
Life sciences, , Volume: 65, Issue:2, 1999

[Hepatic porphyria].
La Revue de medecine interne, , Volume: 20, Issue:4, 1999

Treatment of Parkinson's disease in a patient with acute intermittent porphyria.
British journal of clinical pharmacology, , Volume: 40, Issue:1, 1995

[Anesthetic management of a patient with acute intermittent porphyria].
Masui. The Japanese journal of anesthesiology, , Volume: 42, Issue:12, 1993

ACUTE INTERMITTENT PORPHYRIA IN PREGNANCY; REPORT OF A CASE.
Obstetrics and gynecology, , Volume: 25, 1965

[A CASE OF INTERMITTENT ACUTE PORPHYRIA IN A 52-YEAR-OLD WOMAN, TRIGGERED BY THE INGESTION OF AN ALLYL BARBITURATE].
Acta chirurgica Belgica, , Volume: 63, 1964

[ACUTE PORPHYRIA].
Revista espanola de las enfermedades del aparato digestivo y de la nutricion, , Volume: 22, 1963

[ACUTE IDIOPATHIC PORPHYRIA. APROPOS OF A CASE USING A RESPIRATORY LASTING 4 MONTHS].
Annales medicales de Nancy, , Volume: 2, 1963

Acute intermittent porphyria; report of a case treated with chlorpromazine.
The Journal of the Kansas Medical Society, , Volume: 58, Issue:10, 1957

Intermittent acute porphyria treated with chlorpromazine.
The New England journal of medicine, , Feb-14, Volume: 256, Issue:7, 1957

[Important electroencephalographic changes in acute porphyria treated with chlorpromazine].
Revue neurologique, , Volume: 92, Issue:6, 1955

Cimetidine and acute intermittent porphyria.
Annals of internal medicine, , Nov-01, Volume: 143, Issue:9, 2005

[A family of acute intermittent porphyria].
[Rinsho ketsueki] The Japanese journal of clinical hematology, , Volume: 45, Issue:7, 2004

Cimetidine in the treatment of acute intermittent porphyria.
The Annals of pharmacotherapy, , Volume: 31, Issue:3, 1997

[Cimetidine in treatment of acute intermittent porphyria].
Zeitschrift fur Gastroenterologie, , Volume: 31, Issue:4, 1993

[A case of acute intermittent porphyria treated with cimetidine].
Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine, , Apr-10, Volume: 82, Issue:4, 1993

[Acute intermittent porphyria associated with epilepsy in a child: diagnostic and therapeutic difficulties].
Archives de pediatrie : organe officiel de la Societe francaise de pediatrie, , Volume: 4, Issue:10, 1997

Effects of clonidine in a primed rat model of acute hepatic porphyria.
Arzneimittel-Forschung, , Volume: 47, Issue:6, 1997

Iron chelation rescues hemolytic anemia and skin photosensitivity in congenital erythropoietic porphyria.
Blood, , 11-19, Volume: 136, Issue:21, 2020

delta-Aminolevulinic acid effects on neuronal and glial tumor cell lines.
Neurochemical research, , Volume: 18, Issue:12, 1993

[Epileptic insults, cerebral infarct and rhabdomyolysis as complication of amphetamine use].
Nederlands tijdschrift voor geneeskunde, , Jul-20, Volume: 140, Issue:29, 1996

Drug use in porphyria: a therapeutic dilemma.
Singapore medical journal, , Volume: 49, Issue:10, 2008

[Abdominal pain after taking drug tablets. Acute intermittent porphyria].
MMW Fortschritte der Medizin, , Feb-03, Volume: 142, Issue:5, 2000

The effect of therapeutic drugs and other pharmacologic agents on activity of porphobilinogen deaminase, the enzyme that is deficient in intermittent acute porphyria.
Life sciences, , Volume: 65, Issue:2, 1999

5-Aminolevulinic acid induces single-strand breaks in plasmid pBR322 DNA in the presence of Fe2+ ions.
Biochimica et biophysica acta, , Feb-22, Volume: 1225, Issue:3, 1994

[REANIMATION AND VALUE OF RECENT TREATMENT OF ACUTE PORPHYRIAS].
Bulletins et memoires de la Societe medicale des hopitaux de Paris, , Nov-13, Volume: 115, 1964

[Acute porphyria; 2 cases with distinctive neuropsychiatric symptoms treated with BAL].
Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, , May-01, Volume: 78, Issue:9, 1958

The treatment of acute porphyria with chelating agents: a report of 21 cases.
Annals of internal medicine, , Volume: 47, Issue:5, 1957

Therapy of acute porphyria with BAL and other agents; a report of 19 additional cases.
Diseases of the nervous system, , Volume: 17, Issue:6, 1956

[Acute Intermittent porphyria and valproic acid].
Revista clinica espanola, , Volume: 212, Issue:4, 2012

[Acute intermittent porphyria associated with epilepsy in a child: diagnostic and therapeutic difficulties].
Archives de pediatrie : organe officiel de la Societe francaise de pediatrie, , Volume: 4, Issue:10, 1997

Drug treatment of hypertension in acute intermittent porphyria: doxazosin and amlodipine.
British journal of clinical pharmacology, , Volume: 43, Issue:3, 1997

Heme oxygenase, aminolevulinate acid synthetase and the antioxidant system in the brain of mice treated with porphyrinogenic drugs.
Cellular and molecular biology (Noisy-le-Grand, France), , Oct-03, Volume: 51, Issue:5, 2005

The ether soluble porphyrins found in urine in acute porphyria and porphyria cutanea tarda.
Scandinavian journal of clinical and laboratory investigation, , Volume: 14, 1962

Uneventful propofol anaesthesia in a patient with acute intermittent porphyria.
European journal of anaesthesiology, , Volume: 16, Issue:7, 1999

Axonal Polyneuropathy in a Man Treated for Pulmonary Cocci: A Case of Acute Intermittent Porphyria.
The American journal of case reports, , Sep-18, Volume: 20, 2019

Treatment of neuropathic pain in acute intermittent porphyria with gabapentin.
Journal of the Formosan Medical Association = Taiwan yi zhi, , Volume: 112, Issue:9, 2013

Gabapentin reduces neurovisceral pain of porphyria.
Acta neurologica Taiwanica, , Volume: 19, Issue:2, 2010

Use of propofol anesthesia and adjunctive treatment with levetiracetam and gabapentin in managing status epilepticus in a patient of acute intermittent porphyria.
Epilepsia, , Volume: 49, Issue:5, 2008

Drug use in porphyria: a therapeutic dilemma.
Singapore medical journal, , Volume: 49, Issue:10, 2008

Gabapentin in seizures due to acute intermittent porphyria.
Neurology India, , Volume: 48, Issue:2, 2000

Treatment of seizures in acute intermittent porphyria: safety and efficacy of gabapentin.
Seizure, , Volume: 7, Issue:5, 1998

Gabapentin treatment of seizures in acute intermittent porphyria.
Neurology, , Volume: 45, Issue:6, 1995

Acute intermittent porphyria presenting with neurological emergency: review of six cases.
Neurology India, , Volume: 55, Issue:4

Gabapentin and propofol for treatment of status epilepticus in acute intermittent porphyria.
Journal of postgraduate medicine, , Volume: 49, Issue:3

[Porphyria].
Ryoikibetsu shokogun shirizu, , Issue:40, 2003

Safe use of haloperidol in acute intermittent porphyria.
The Annals of pharmacotherapy, , Volume: 29, Issue:2, 1995

[Fatal postoperative crisis in acute hereditary porphyria].
La Tunisie medicale, , Volume: 80, Issue:5, 2002

ACUTE INTERMITTENT PORPHYRIA: THE ANAESTHETIC PROBLEM AND ITS BACKGROUND.
British journal of anaesthesia, , Volume: 36, 1964

Systemic lupus erythematosus and hydroxychloroquine-related acute intermittent porphyria.
Rheumatology international, , Volume: 40, Issue:5, 2020

The effect of therapeutic drugs and other pharmacologic agents on activity of porphobilinogen deaminase, the enzyme that is deficient in intermittent acute porphyria.
Life sciences, , Volume: 65, Issue:2, 1999

Heme oxygenase, aminolevulinate acid synthetase and the antioxidant system in the brain of mice treated with porphyrinogenic drugs.
Cellular and molecular biology (Noisy-le-Grand, France), , Oct-03, Volume: 51, Issue:5, 2005

[Desflurane in acute intermittent porphyria].
Der Anaesthesist, , Volume: 53, Issue:3, 2004

Administration of the anesthetic isoflurane to mice: a model for acute intermittent porphyria?
Journal of pharmacological and toxicological methods, , Volume: 28, Issue:4, 1992

Increased delta aminolevulinic acid and decreased pineal melatonin production. A common event in acute porphyria studies in the rat.
The Journal of clinical investigation, , Jan-01, Volume: 97, Issue:1, 1996

Ketamine in porphyria.
Anesthesia and analgesia, , Volume: 84, Issue:6, 1997

Reversible encephalopathy syndrome in acute porphyria attack.
Medicina clinica, , 10-11, Volume: 153, Issue:7, 2019

[Acute porphyria and multiple organ failure during treatment with lamotrigine].
Ugeskrift for laeger, , Jul-08, Volume: 158, Issue:28, 1996

Anticancer therapy in patients with porphyrias: evidence today.
Expert opinion on drug safety, , Volume: 7, Issue:2, 2008

Acute intermittent porphyria presenting with neurological emergency: review of six cases.
Neurology India, , Volume: 55, Issue:4

[Hepatic porphyria].
La Revue de medecine interne, , Volume: 20, Issue:4, 1999

[Patient-controlled analgesia with pethidine in acute intermittent porphyria].
Deutsche medizinische Wochenschrift (1946), , Oct-20, Volume: 120, Issue:42, 1995

Acute porphyrias may be overlooked in patients taking methenamine hippurate.
Clinical chemistry and laboratory medicine, , Volume: 48, Issue:9, 2010

Metoclopramide and acute porphyria.
Lancet (London, England), , Oct-11, Volume: 350, Issue:9084, 1997

Acute intermittent porphyria precipitated by hyperemesis and metoclopramide treatment in pregnancy.
Acta obstetricia et gynecologica Scandinavica, , Volume: 76, Issue:5, 1997

[Mitotane as possible cause of acute intermittent porphyria].
Ugeskrift for laeger, , Sep-12, Volume: 173, Issue:37, 2011

[Prostigmine therapy of acute porphyria].
Nordisk medicin, , Mar-13, Volume: 49, Issue:11, 1953

Acute porphyria precipitated by nevirapine.
AIDS (London, England), , Oct-23, Volume: 24, Issue:16, 2010

[Paranoid psychosis in acute intermittent porphyria treated with perphenazine].
Ugeskrift for laeger, , Nov-02, Volume: 160, Issue:45, 1998

Acute porphyria and one false initial diagnosis due to the previous taking of pyridium.
Virginia medical monthly, , Volume: 79, Issue:7, 1952

Characterization of the hepatic transcriptome following phenobarbital induction in mice with AIP.
Molecular genetics and metabolism, , Volume: 128, Issue:3, 2019

Sex differences in vascular reactivity in mesenteric arteries from a mouse model of acute intermittent porphyria.
Molecular genetics and metabolism, , Volume: 128, Issue:3, 2019

Computational disease model of phenobarbital-induced acute attacks in an acute intermittent porphyria mouse model.
Molecular genetics and metabolism, , Volume: 128, Issue:3, 2019

Homozygous hydroxymethylbilane synthase knock-in mice provide pathogenic insights into the severe neurological impairments present in human homozygous dominant acute intermittent porphyria.
Human molecular genetics, , 06-01, Volume: 28, Issue:11, 2019

Bioengineered PBGD variant improves the therapeutic index of gene therapy vectors for acute intermittent porphyria.
Human molecular genetics, , 11-01, Volume: 27, Issue:21, 2018

Mitochondrial energetic defects in muscle and brain of a Hmbs-/- mouse model of acute intermittent porphyria.
Human molecular genetics, , Sep-01, Volume: 24, Issue:17, 2015

A case of repeated coma in an 8-year-old boy.
Tropical doctor, , Volume: 37, Issue:4, 2007

Adenoviral-mediated expression of porphobilinogen deaminase in liver restores the metabolic defect in a mouse model of acute intermittent porphyria.
Molecular therapy : the journal of the American Society of Gene Therapy, , Volume: 10, Issue:2, 2004

Zinc mesoporphyrin represses induced hepatic 5-aminolevulinic acid synthase and reduces heme oxygenase activity in a mouse model of acute hepatic porphyria.
Hepatology (Baltimore, Md.), , Volume: 33, Issue:5, 2001

Acute intermittent porphyria, seizures, and antiepileptic drugs: a report on a 3-year-old Nigerian boy.
Seizure, , Volume: 10, Issue:1, 2001

The effect of therapeutic drugs and other pharmacologic agents on activity of porphobilinogen deaminase, the enzyme that is deficient in intermittent acute porphyria.
Life sciences, , Volume: 65, Issue:2, 1999

Porphobilinogen deaminase deficiency in mice causes a neuropathy resembling that of human hepatic porphyria.
Nature genetics, , Volume: 12, Issue:2, 1996

[Case history--red urine].
Revue medicale de la Suisse romande, , Volume: 115, Issue:4, 1995

[Two cases of acute porphyria].
Japanese journal of medical science & biology, , Mar-10, Volume: 51, 1963

Biochemical characterization of porphobilinogen deaminase-deficient mice during phenobarbital induction of heme synthesis and the effect of enzyme replacement.
Molecular medicine (Cambridge, Mass.), , Volume: 9, Issue:9-12

Use of propofol anesthesia and adjunctive treatment with levetiracetam and gabapentin in managing status epilepticus in a patient of acute intermittent porphyria.
Epilepsia, , Volume: 49, Issue:5, 2008

Levetiracetam in porphyric status epilepticus: a case report.
Clinical neuropharmacology, , Volume: 28, Issue:5

[Porphyria].
Ryoikibetsu shokogun shirizu, , Issue:40, 2003

Acute porphyria.
Annals of internal medicine, , Volume: 38, Issue:4, 1953

ACUTE INTERMITTENT PORPHYRIA.
The Journal of the Medical Society of New Jersey, , Volume: 61, 1964

Drug use in porphyria: a therapeutic dilemma.
Singapore medical journal, , Volume: 49, Issue:10, 2008

The effect of therapeutic drugs and other pharmacologic agents on activity of porphobilinogen deaminase, the enzyme that is deficient in intermittent acute porphyria.
Life sciences, , Volume: 65, Issue:2, 1999

[A CASE OF INTERMITTENT ACUTE PORPHYRIA IN A 52-YEAR-OLD WOMAN, TRIGGERED BY THE INGESTION OF AN ALLYL BARBITURATE].
Acta chirurgica Belgica, , Volume: 63, 1964

Drug use in porphyria: a therapeutic dilemma.
Singapore medical journal, , Volume: 49, Issue:10, 2008

Favourable effect of intravenous propranolol in acute intermittent porphyria.
Monographs in human genetics, , Volume: 10, 1978

The use of rocuronium and sevoflurane in acute intermittent porphyria--a case report.
Acta anaesthesiologica Taiwanica : official journal of the Taiwan Society of Anesthesiologists, , Volume: 44, Issue:3, 2006

[A case report of rapid inhalation induction with sevoflurane in a patient with porphyria].
Masui. The Japanese journal of anesthesiology, , Volume: 54, Issue:11, 2005

Anesthesia in a child with homozygous porphobilinogen deaminase deficiency: a severe form of acute intermittent porphyria.
Paediatric anaesthesia, , Volume: 15, Issue:5, 2005

Sevoflurane in acute intermittent porphyria.
Anaesthesia, , Volume: 56, Issue:10, 2001

The use of sevoflurane in acute intermittent porphyria.
Anaesthesia, , Volume: 56, Issue:4, 2001

Increased delta aminolevulinic acid and decreased pineal melatonin production. A common event in acute porphyria studies in the rat.
The Journal of clinical investigation, , Jan-01, Volume: 97, Issue:1, 1996

Suxamethonium in the intensive care unit: "Fool me once, shame on you; fool me twice, shame on me".
Intensive care medicine, , Volume: 34, Issue:1, 2008

ACUTE INTERMITTENT PORPHYRIA: THE ANAESTHETIC PROBLEM AND ITS BACKGROUND.
British journal of anaesthesia, , Volume: 36, 1964

New symptomatic treatment for acute intermittent porphyria.
A.M.A. archives of internal medicine, , Volume: 89, Issue:1, 1952

Acute intermittent porphyria treated with trifluoperazine.
United States Armed Forces medical journal, , Volume: 10, 1959

Treatment of Parkinson's disease in a patient with acute intermittent porphyria.
British journal of clinical pharmacology, , Volume: 40, Issue:1, 1995

How porphyrinogenic drugs modeling acute porphyria impair the hormonal status that regulates glucose metabolism. Their relevance in the onset of this disease.
Toxicology, , Nov-28, Volume: 290, Issue:1, 2011

Renal transplantation in a case of acute intermittent porphyria.
Journal of clinical pharmacology, , Volume: 43, Issue:10, 2003

[A CASE OF INTERMITTENT ACUTE PORPHYRIA IN A 52-YEAR-OLD WOMAN, TRIGGERED BY THE INGESTION OF AN ALLYL BARBITURATE].
Acta chirurgica Belgica, , Volume: 63, 1964

ELEVATION OF THE SERUM PROTEIN-BOUND IODINE IN ACUTE INTERMITTENT PORPHYRIA.
The Journal of clinical endocrinology and metabolism, , Volume: 23, 1963

Gas chromatography-mass spectrometry profiling of steroids in urine of patients with acute intermittent porphyria.
Clinical biochemistry, , Volume: 46, Issue:9, 2013

ACUTE INTERMITTENT PORPHYRIA.
The Journal of the Medical Society of New Jersey, , Volume: 61, 1964

Gas chromatography-mass spectrometry profiling of steroids in urine of patients with acute intermittent porphyria.
Clinical biochemistry, , Volume: 46, Issue:9, 2013

ORAL CONTRACEPTIVES AND ACUTE INTERMITTENT PORPHYRIA.
Lancet (London, England), , Jan-30, Volume: 1, Issue:7379, 1965

ORAL CONTRACEPTIVES AND ACUTE INTERMITTENT PORPHYRIA.
Lancet (London, England), , Nov-28, Volume: 2, Issue:7370, 1964

FACTORS AFFECTING THE EXCRETION OF PORPHYRIN PRECURSORS BY PATIENTS WITH ACUTE INTERMITTENT PORPHYRIA. II. THE EFFECT OF ETHINYL ESTRADIOL.
Metabolism: clinical and experimental, , Volume: 13, 1964

[Case history--red urine].
Revue medicale de la Suisse romande, , Volume: 115, Issue:4, 1995

Non-viral delivery of the porphobilinogen deaminase cDNA into a mouse model of acute intermittent porphyria.
Molecular genetics and metabolism, , Volume: 82, Issue:1, 2004

Sex differences in vascular reactivity in mesenteric arteries from a mouse model of acute intermittent porphyria.
Molecular genetics and metabolism, , Volume: 128, Issue:3, 2019

Treatment of Parkinson's disease in a patient with acute intermittent porphyria.
British journal of clinical pharmacology, , Volume: 40, Issue:1, 1995

[REANIMATION AND VALUE OF RECENT TREATMENT OF ACUTE PORPHYRIAS].
Bulletins et memoires de la Societe medicale des hopitaux de Paris, , Nov-13, Volume: 115, 1964

ACUTE INTERMITTENT PORPHYRIA.
The Journal of the Medical Society of New Jersey, , Volume: 61, 1964

The use of chelating agents in the treatment of acute porphyria.
Annals of internal medicine, , Volume: 50, Issue:4, 1959

The treatment of acute porphyria with chelating agents: a report of 21 cases.
Annals of internal medicine, , Volume: 47, Issue:5, 1957

[Acute idiopathic porphyria with abdominal onset; neurological syndrome appearing after surgery; therapy with glycocoll & edathamil calcium].
Bulletins et memoires de la Societe medicale des hopitaux de Paris, , Volume: 75, Issue:9-11

RENAL MECHANISM FOR EXCRETION OF PORPHYRIN PRECURSORS IN PATIENTS WITH ACUTE INTERMITTENT PORPHYRIA AND CHRONIC LEAD POISONING.
Blood, , Volume: 26, 1965

Studies in porphyria. VIII. Relationship of the 5 alpha-reductive metabolism of steroid hormones to clinical expression of the genetic defect in acute intermittent porphyria.
The American journal of medicine, , Volume: 66, Issue:4, 1979

Dysregulation of homocysteine homeostasis in acute intermittent porphyria patients receiving heme arginate or givosiran.
Journal of inherited metabolic disease, , Volume: 44, Issue:4, 2021

Identification and characterization of two novel mutations that produce acute intermittent porphyria: A 3-base deletion (841-843delGGA) and a missense mutation (T35M).
Human mutation, , Volume: 16, Issue:4, 2000

Differential regulation of human ALAS1 mRNA and protein levels by heme and cobalt protoporphyrin.
Molecular and cellular biochemistry, , Volume: 319, Issue:1-2, 2008

[REANIMATION AND VALUE OF RECENT TREATMENT OF ACUTE PORPHYRIAS].
Bulletins et memoires de la Societe medicale des hopitaux de Paris, , Nov-13, Volume: 115, 1964

[A CASE OF INTERMITTENT ACUTE PORPHYRIA IN A 52-YEAR-OLD WOMAN, TRIGGERED BY THE INGESTION OF AN ALLYL BARBITURATE].
Acta chirurgica Belgica, , Volume: 63, 1964

ORAL CONTRACEPTIVES AND ACUTE INTERMITTENT PORPHYRIA.
Lancet (London, England), , Jan-30, Volume: 1, Issue:7379, 1965

Acute intermittent porphyria caused by an arginine to histidine substitution (R26H) in the cofactor-binding cleft of porphobilinogen deaminase.
Human molecular genetics, , Volume: 2, Issue:8, 1993

28-Year-Old Woman With Severe Generalized Abdominal Pain.
Mayo Clinic proceedings, , Volume: 94, Issue:7, 2019

Identification and characterization of two novel mutations that produce acute intermittent porphyria: A 3-base deletion (841-843delGGA) and a missense mutation (T35M).
Human mutation, , Volume: 16, Issue:4, 2000

ORAL CONTRACEPTIVES AND ACUTE INTERMITTENT PORPHYRIA.
Lancet (London, England), , Nov-28, Volume: 2, Issue:7370, 1964

Evaluation of Metabolic Changes in Acute Intermittent Porphyria Patients by Targeted Metabolomics.
International journal of molecular sciences, , Mar-16, Volume: 23, Issue:6, 2022

Comprehensive analysis of the tryptophan metabolome in urine of patients with acute intermittent porphyria.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, , Aug-15, Volume: 1060, 2017

Increased delta aminolevulinic acid and decreased pineal melatonin production. A common event in acute porphyria studies in the rat.
The Journal of clinical investigation, , Jan-01, Volume: 97, Issue:1, 1996

Decreased nocturnal plasma melatonin levels in patients with recurrent acute intermittent porphyria attacks.
Life sciences, , Volume: 53, Issue:8, 1993

RENAL MECHANISM FOR EXCRETION OF PORPHYRIN PRECURSORS IN PATIENTS WITH ACUTE INTERMITTENT PORPHYRIA AND CHRONIC LEAD POISONING.
Blood, , Volume: 26, 1965

ELEVATION OF THE SERUM PROTEIN-BOUND IODINE IN ACUTE INTERMITTENT PORPHYRIA.
The Journal of clinical endocrinology and metabolism, , Volume: 23, 1963

Solving electrolyte disturbances with the Ehrlich reagent.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, , Volume: 18, Issue:6, 2003

Network analysis of hydroxymethylbilane synthase dynamics.
Journal of molecular graphics & modelling, , Volume: 99, 2020

Human hydroxymethylbilane synthase: Molecular dynamics of the pyrrole chain elongation identifies step-specific residues that cause AIP.
Proceedings of the National Academy of Sciences of the United States of America, , 04-24, Volume: 115, Issue:17, 2018

RENAL MECHANISM FOR EXCRETION OF PORPHYRIN PRECURSORS IN PATIENTS WITH ACUTE INTERMITTENT PORPHYRIA AND CHRONIC LEAD POISONING.
Blood, , Volume: 26, 1965

ACUTE INTERMITTENT PORPHYRIA; DIAGNOSIS FOUR YEARS POST MORTEM BY CHEMICAL STUDIES IN RELATIVES.
Scandinavian journal of clinical and laboratory investigation, , Volume: 16, 1964

FACTORS AFFECTING THE EXCRETION OF PORPHYRIN PRECURSORS BY PATIENTS WITH ACUTE INTERMITTENT PORPHYRIA. II. THE EFFECT OF ETHINYL ESTRADIOL.
Metabolism: clinical and experimental, , Volume: 13, 1964

FACTORS AFFECTING THE EXCRETION OF PORPHYRIN PRECURSORS BY PATIENTS WITH ACUTE INTERMITTENT PORPHYRIA. I. THE EFFECT OF DIET.
Metabolism: clinical and experimental, , Volume: 13, 1964

EFFECT OF GRISEOFLUVIN IN ACUTE INTERMITTENT PORPHYRIA.
JAMA, , May-04, Volume: 188, 1964

Excretion of porphobilinogen and 5-aminolaevulinic acid in acute porphyria.
Lancet (London, England), , Jun-10, Volume: 1, Issue:7189, 1961

Uncontrolled Acute Intermittent Porphyria as a Cause of Spontaneous Abortion.
Medical archives (Sarajevo, Bosnia and Herzegovina), , Volume: 74, Issue:2, 2020

Is 5-aminolevulinic acid involved in the hepatocellular carcinogenesis of acute intermittent porphyria?
Cellular and molecular biology (Noisy-le-Grand, France), , Volume: 48, Issue:1, 2002

Alterations of the redox state, pentose pathway and glutathione metabolism in an acute porphyria model. Their impact on heme pathway.
Experimental biology and medicine (Maywood, N.J.), , Volume: 238, Issue:2, 2013

Metabolization of porphyrinogenic agents in brain: involvement of the phase I drug metabolizing system. A comparative study in liver and kidney.
Cellular and molecular neurobiology, , Volume: 27, Issue:6, 2007

Response of glucose metabolism enzymes in an acute porphyria model. Role of reactive oxygen species.
Toxicology, , Volume: 216, Issue:1, 2005

Effects of clonidine in a primed rat model of acute hepatic porphyria.
Arzneimittel-Forschung, , Volume: 47, Issue:6, 1997

STZ-induced diabetes in mice and heme pathway enzymes. Effect of allylisopropylacetamide and alpha-tocopherol.
Chemico-biological interactions, , Apr-14, Volume: 95, Issue:3, 1995

Inhibition of 5-aminolevulinic acid-induced DNA damage by melatonin, N1-acetyl-N2-formyl-5-methoxykynuramine, quercetin or resveratrol.
Journal of pineal research, , Volume: 38, Issue:2, 2005

ORAL CONTRACEPTIVES AND ACUTE INTERMITTENT PORPHYRIA.
Lancet (London, England), , Jan-30, Volume: 1, Issue:7379, 1965

FACTORS AFFECTING THE EXCRETION OF PORPHYRIN PRECURSORS BY PATIENTS WITH ACUTE INTERMITTENT PORPHYRIA. II. THE EFFECT OF ETHINYL ESTRADIOL.
Metabolism: clinical and experimental, , Volume: 13, 1964

[Acute intermittent porphyria and apiol absorption].
Bulletin de la Federation des societes de gynecologie et dobstetrique de langue francaise, , Volume: 6, Issue:3, 1954

The biochemistry of heme synthesis in porphyria and in the porphyrinurias.
Clinics in dermatology, , Volume: 16, Issue:2

ORAL CONTRACEPTIVES AND ACUTE INTERMITTENT PORPHYRIA.
Lancet (London, England), , Jan-30, Volume: 1, Issue:7379, 1965

RENAL MECHANISM FOR EXCRETION OF PORPHYRIN PRECURSORS IN PATIENTS WITH ACUTE INTERMITTENT PORPHYRIA AND CHRONIC LEAD POISONING.
Blood, , Volume: 26, 1965

ACUTE INTERMITTENT PORPHYRIA; DIAGNOSIS FOUR YEARS POST MORTEM BY CHEMICAL STUDIES IN RELATIVES.
Scandinavian journal of clinical and laboratory investigation, , Volume: 16, 1964

FACTORS AFFECTING THE EXCRETION OF PORPHYRIN PRECURSORS BY PATIENTS WITH ACUTE INTERMITTENT PORPHYRIA. II. THE EFFECT OF ETHINYL ESTRADIOL.
Metabolism: clinical and experimental, , Volume: 13, 1964

FACTORS AFFECTING THE EXCRETION OF PORPHYRIN PRECURSORS BY PATIENTS WITH ACUTE INTERMITTENT PORPHYRIA. I. THE EFFECT OF DIET.
Metabolism: clinical and experimental, , Volume: 13, 1964

Induction of the synthesis of delta-aminolevulinic acid synthetase in liver parenchyma cells in culture by chemical that induce acute porphyria.
The Journal of biological chemistry, , Volume: 238, 1963

Alterations of the redox state, pentose pathway and glutathione metabolism in an acute porphyria model. Their impact on heme pathway.
Experimental biology and medicine (Maywood, N.J.), , Volume: 238, Issue:2, 2013

Response of glucose metabolism enzymes in an acute porphyria model. Role of reactive oxygen species.
Toxicology, , Volume: 216, Issue:1, 2005

Effects of clonidine in a primed rat model of acute hepatic porphyria.
Arzneimittel-Forschung, , Volume: 47, Issue:6, 1997

STZ-induced diabetes in mice and heme pathway enzymes. Effect of allylisopropylacetamide and alpha-tocopherol.
Chemico-biological interactions, , Apr-14, Volume: 95, Issue:3, 1995

[Altered orientation and aggressiveness in an 89-year-old woman].
Der Internist, , Volume: 59, Issue:1, 2018

Acute porphyria. III. The separation of preformed porphyrin and porphobilinogen in the urine in acute porphyria; a coproporphyrin chromogen in normal and pathological urine.
Scandinavian journal of clinical and laboratory investigation, , Volume: 3, Issue:2, 1951

Acute porphyrias may be overlooked in patients taking methenamine hippurate.
Clinical chemistry and laboratory medicine, , Volume: 48, Issue:9, 2010

Effects of administration of antioxidants in acute intermittent porphyria.
European journal of clinical chemistry and clinical biochemistry : journal of the Forum of European Clinical Chemistry Societies, , Volume: 35, Issue:6, 1997

Pathogenic mechanisms of the acute porphyric attack: speculative roles of manganese associated enzymes.
Cellular and molecular biology (Noisy-le-Grand, France), , Volume: 43, Issue:1, 1997

[Toxic effects of cadmium on the human body (literature review)].
Meditsina truda i promyshlennaia ekologiia, , Issue:6, 2012

Acute porphyria. I. Some observations on the solubility, precipitation, fluorescence and absorption spectra of calcium phosphate-adsorbed porphyrin pigments.
Scandinavian journal of clinical and laboratory investigation, , Volume: 3, Issue:2, 1951

[NEUROLOGICAL AND PSYCHIC DISORDERS IN PORPHYRIA. 1. ACUTE INTERMITTENT PORPHYRIA--TOXIC PORPHYRIA].
Psychiatrie, Neurologie, und medizinische Psychologie, , Volume: 16, 1964

Solving electrolyte disturbances with the Ehrlich reagent.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, , Volume: 18, Issue:6, 2003

Gabapentin in seizures due to acute intermittent porphyria.
Neurology India, , Volume: 48, Issue:2, 2000

Treatment of seizures in acute intermittent porphyria: safety and efficacy of gabapentin.
Seizure, , Volume: 7, Issue:5, 1998

Gabapentin treatment of seizures in acute intermittent porphyria.
Neurology, , Volume: 45, Issue:6, 1995

Gabapentin and propofol for treatment of status epilepticus in acute intermittent porphyria.
Journal of postgraduate medicine, , Volume: 49, Issue:3

Women with acute intermittent porphyria have a defect in 5α-steroid production during the menstrual cycle.
Acta obstetricia et gynecologica Scandinavica, , Volume: 91, Issue:12, 2012

Acute intermittent porphyria: Acute flare-up resolved with givosiran.
Medicina clinica, , Nov-24, Volume: 161, Issue:10, 2023

RNAi therapy with givosiran significantly reduces attack rates in acute intermittent porphyria.
Journal of internal medicine, , Volume: 291, Issue:5, 2022

Givosiran in acute intermittent porphyria: A personalized medicine approach.
Molecular genetics and metabolism, , Volume: 135, Issue:3, 2022

Efficacy and safety of givosiran for acute hepatic porphyria: 24-month interim analysis of the randomized phase 3 ENVISION study.
Liver international : official journal of the International Association for the Study of the Liver, , Volume: 42, Issue:1, 2022

Acute intermittent porphyria, givosiran, and homocysteine.
Journal of inherited metabolic disease, , Volume: 44, Issue:4, 2021

Severe homocysteinemia in two givosiran-treated porphyria patients: is free heme deficiency the culprit?
Annals of hematology, , Volume: 100, Issue:7, 2021

Givosiran: A Review in Acute Hepatic Porphyria.
Drugs, , Volume: 81, Issue:7, 2021

Dysregulation of homocysteine homeostasis in acute intermittent porphyria patients receiving heme arginate or givosiran.
Journal of inherited metabolic disease, , Volume: 44, Issue:4, 2021

Givosiran to treat acute porphyria.
Drugs of today (Barcelona, Spain : 1998), , Volume: 57, Issue:1, 2021

Case report of a complicated neurologically manifesting acute porphyria treated successfully with Givosiran.
Journal of the neurological sciences, , 03-15, Volume: 422, 2021

Givosiran for Acute Intermittent Porphyria. Reply.
The New England journal of medicine, , 11-12, Volume: 383, Issue:20, 2020

Givosiran for Acute Intermittent Porphyria.
The New England journal of medicine, , 11-12, Volume: 383, Issue:20, 2020

Cost savings with hemin versus givosiran for the treatment of patients with acute intermittent porphyria (AIP).
Journal of medical economics, , Volume: 23, Issue:12, 2020

[Phase 3 Trial of RNAi Therapeutic Givosiran for Acute Intermittent Porphyria].
Zeitschrift fur Gastroenterologie, , Volume: 58, Issue:8, 2020

Givosiran - Running RNA Interference to Fight Porphyria Attacks.
The New England journal of medicine, , 06-11, Volume: 382, Issue:24, 2020

Phase 3 Trial of RNAi Therapeutic Givosiran for Acute Intermittent Porphyria.
The New England journal of medicine, , 06-11, Volume: 382, Issue:24, 2020

Pharmacokinetics and Pharmacodynamics of the Small Interfering Ribonucleic Acid, Givosiran, in Patients With Acute Hepatic Porphyria.
Clinical pharmacology and therapeutics, , Volume: 108, Issue:1, 2020

Leading RNA Interference Therapeutics Part 2: Silencing Delta-Aminolevulinic Acid Synthase 1, with a Focus on Givosiran.
Molecular diagnosis & therapy, , Volume: 24, Issue:1, 2020

Phase 1 Trial of an RNA Interference Therapy for Acute Intermittent Porphyria.
The New England journal of medicine, , 02-07, Volume: 380, Issue:6, 2019

[Acute intermittent porphyria and oral contraception. Case report].
Ginekologia polska, , Volume: 77, Issue:3, 2006

[Desflurane in acute intermittent porphyria].
Der Anaesthesist, , Volume: 53, Issue:3, 2004

Management of parkinsonism and psychotic depression in a case of acute intermittent porphyria.
Journal of neurology, neurosurgery, and psychiatry, , Volume: 62, Issue:5, 1997

[GnRH agonists in acute intermittent porphyria].
Deutsche medizinische Wochenschrift (1946), , Dec-11, Volume: 117, Issue:50, 1992

Anaesthesia for the porphyric patient.
Anaesthesia, , Volume: 48, Issue:11, 1993

Remifentanil and acute intermittent porphyria.
European journal of anaesthesiology, , Volume: 19, Issue:11, 2002

False-positive accumulation of metaiodobenzylguanidine in a case with acute intermittent porphyria.
Internal medicine (Tokyo, Japan), , Volume: 50, Issue:9, 2011

[Clinical and therapeutic remarks apropos of a case of acute porphyria. Favorable action of adenosine monophosphoric acid].
Lyon medical, , Jul-07, Volume: 210, 1963

ALAS1 gene expression is down-regulated by Akt-mediated phosphorylation and nuclear exclusion of FOXO1 by vanadate in diabetic mice.
The Biochemical journal, , Mar-01, Volume: 442, Issue:2, 2012

Acute porphyria precipitated by efavirenz.
AIDS (London, England), , May-15, Volume: 29, Issue:8, 2015

Acute intermittent porphyria: is oseltamivir safe in these patients?
Clinical medicine (London, England), , Volume: 22, Issue:3, 2022

Alterations of the redox state, pentose pathway and glutathione metabolism in an acute porphyria model. Their impact on heme pathway.
Experimental biology and medicine (Maywood, N.J.), , Volume: 238, Issue:2, 2013

Anticancer therapy in patients with porphyrias: evidence today.
Expert opinion on drug safety, , Volume: 7, Issue:2, 2008

Voriconazole-induced pseudoporphyria.
Photodermatology, photoimmunology & photomedicine, , Volume: 23, Issue:1, 2007

Pseudoporphyria as a result of voriconazole use: a case report.
International journal of dermatology, , Volume: 43, Issue:10, 2004

Remarks on the acute intermittent porphyria.
Annals of clinical biochemistry, , Volume: 46, Issue:Pt 4, 2009

Investigations on the formation of urinary coproporphyrin isomers I-IV in 5-aminolevulinic acid dehydratase deficiency porphyria, acute lead intoxication and after oral 5-aminolevulinic acid loading.
Clinical biochemistry, , Volume: 32, Issue:2, 1999

Voriconazole-induced pseudoporphyria.
Photodermatology, photoimmunology & photomedicine, , Volume: 23, Issue:1, 2007

Pseudoporphyria as a result of voriconazole use: a case report.
International journal of dermatology, , Volume: 43, Issue:10, 2004

Liver Transplantation for Acute Intermittent Porphyria: Biochemical and Pathologic Studies of the Explanted Liver.
Molecular medicine (Cambridge, Mass.), , Jun-05, Volume: 21, 2015

[Acute porphyria with porphyrins with 3, 5 and 7 carboxyls in urine in addition to uroporphyrin III; a clinical and biochemical study].
La Presse medicale, , Jul-04, Volume: 61, Issue:46, 1953

Remarks on the acute intermittent porphyria.
Annals of clinical biochemistry, , Volume: 46, Issue:Pt 4, 2009

Acute porphyria; investigations on the pathology of the porphyrins and identification of the excretion of uroporphyrin I.
Archives of internal medicine (Chicago, Ill. : 1908), , Volume: 77, 1946

Hyperhomocysteinemia in patients with acute porphyrias: a possible effect of ALAS1 modulation by siRNAm therapy and its control by vitamin supplementation.
European journal of internal medicine, , Volume: 92, 2021

Acute intermittent porphyria, givosiran, and homocysteine.
Journal of inherited metabolic disease, , Volume: 44, Issue:4, 2021

Severe homocysteinemia in two givosiran-treated porphyria patients: is free heme deficiency the culprit?
Annals of hematology, , Volume: 100, Issue:7, 2021

Dysregulation of homocysteine homeostasis in acute intermittent porphyria patients receiving heme arginate or givosiran.
Journal of inherited metabolic disease, , Volume: 44, Issue:4, 2021

Hyperhomocysteinemia in patients with acute porphyrias: A potentially dangerous metabolic crossroad?
European journal of internal medicine, , Volume: 79, 2020

Gas chromatography-mass spectrometry profiling of steroids in urine of patients with acute intermittent porphyria.
Clinical biochemistry, , Volume: 46, Issue:9, 2013

[On the treatment of acute intermittent porphyria].
Orvosi hetilap, , Jun-23, Volume: 104, 1963

Vitamin B6 and oxalic acid in clinical nephrology.
Journal of renal nutrition : the official journal of the Council on Renal Nutrition of the National Kidney Foundation, , Volume: 20, Issue:5 Suppl, 2010

Differential regulation of human ALAS1 mRNA and protein levels by heme and cobalt protoporphyrin.
Molecular and cellular biochemistry, , Volume: 319, Issue:1-2, 2008

Is 5-aminolevulinic acid involved in the hepatocellular carcinogenesis of acute intermittent porphyria?
Cellular and molecular biology (Noisy-le-Grand, France), , Volume: 48, Issue:1, 2002

DNA alkylation by 4,5-dioxovaleric acid, the final oxidation product of 5-aminolevulinic acid.
Chemical research in toxicology, , Volume: 11, Issue:2, 1998

Investigations on the formation of urinary coproporphyrin isomers I-IV in 5-aminolevulinic acid dehydratase deficiency porphyria, acute lead intoxication and after oral 5-aminolevulinic acid loading.
Clinical biochemistry, , Volume: 32, Issue:2, 1999

Is 5-aminolevulinic acid involved in the hepatocellular carcinogenesis of acute intermittent porphyria?
Cellular and molecular biology (Noisy-le-Grand, France), , Volume: 48, Issue:1, 2002

DNA alkylation by 4,5-dioxovaleric acid, the final oxidation product of 5-aminolevulinic acid.
Chemical research in toxicology, , Volume: 11, Issue:2, 1998

Methotrexate and actinomycin D chemotherapy in a patient with porphyria: a case report.
Journal of medical case reports, , Jan-18, Volume: 10, 2016

Anticancer therapy in patients with porphyrias: evidence today.
Expert opinion on drug safety, , Volume: 7, Issue:2, 2008

Rhodococcus equi Pneumonia in Kidney Transplant Recipient Affected by Acute Intermittent Porphyria: A Case Report.
Transplantation proceedings, , Volume: 51, Issue:1

Acute intermittent porphyria precipitated by atazanavir/ritonavir.
International journal of STD & AIDS, , Volume: 27, Issue:13, 2016

Studies in the metabolism of zinc. IV. Some observations on the urinary zinc-porphyrin relationship in non-porphyrics and in a patient with acute intermittent porphyria.
South African journal of laboratory and clinical medicine. Suid-Afrikaanse tydskrif vir laboratorium- en kliniekwerk, , Volume: 8, 1962

[Acute intermittent porphyria revealed by a paradoxical reaction to a benzodiazepine].
Gastroenterologie clinique et biologique, , Volume: 25, Issue:8-9

[Intermittent acute porphyria].
Nederlands tijdschrift voor geneeskunde, , Mar-09, Volume: 101, Issue:10, 1957

Acute porphyria.
Treatment services bulletin. Canada. Department of Veterans' Affairs, , Volume: 6, Issue:11, 1951

Acute porphyria.
Canadian Medical Association journal, , Volume: 65, Issue:6, 1951

Acute intermittent porphyria precipitated by atazanavir/ritonavir.
International journal of STD & AIDS, , Volume: 27, Issue:13, 2016

Anesthesia for cesarian section in pregnant woman with acute intermittent porphyria and hypothyroidism--case report.
Middle East journal of anaesthesiology, , Volume: 21, Issue:3, 2011

Rhodococcus equi Pneumonia in Kidney Transplant Recipient Affected by Acute Intermittent Porphyria: A Case Report.
Transplantation proceedings, , Volume: 51, Issue:1

Metabolization of porphyrinogenic agents in brain: involvement of the phase I drug metabolizing system. A comparative study in liver and kidney.
Cellular and molecular neurobiology, , Volume: 27, Issue:6, 2007

Heme oxygenase, aminolevulinate acid synthetase and the antioxidant system in the brain of mice treated with porphyrinogenic drugs.
Cellular and molecular biology (Noisy-le-Grand, France), , Oct-03, Volume: 51, Issue:5, 2005

PRECIPITATION OF ACUTE INTERMITTENT PORPHYRIA BY GRISEOFULVIN THERAPY.
JAMA, , Jun-14, Volume: 192, 1965

EFFECT OF GRISEOFLUVIN IN ACUTE INTERMITTENT PORPHYRIA.
JAMA, , May-04, Volume: 188, 1964

The use of rocuronium and sevoflurane in acute intermittent porphyria--a case report.
Acta anaesthesiologica Taiwanica : official journal of the Taiwan Society of Anesthesiologists, , Volume: 44, Issue:3, 2006

Use of gonadotropin-releasing hormone analog with tibolone to prevent cyclic attacks of acute intermittent porphyria.
Metabolism: clinical and experimental, , Volume: 50, Issue:9, 2001

Inhibition of 5-aminolevulinic acid-induced DNA damage by melatonin, N1-acetyl-N2-formyl-5-methoxykynuramine, quercetin or resveratrol.
Journal of pineal research, , Volume: 38, Issue:2, 2005

[Two cases of acute porphyria].
Japanese journal of medical science & biology, , Mar-10, Volume: 51, 1963

Pretransplant evaluation of a patient with acute intermittent porphyria.
Progress in transplantation (Aliso Viejo, Calif.), , Volume: 11, Issue:3, 2001

The tolerability of newer immunosuppressive medications in a patient with acute intermittent porphyria.
Journal of clinical pharmacology, , Volume: 41, Issue:1, 2001

Renal transplantation in a case of acute intermittent porphyria.
Journal of clinical pharmacology, , Volume: 43, Issue:10, 2003

Rhodococcus equi Pneumonia in Kidney Transplant Recipient Affected by Acute Intermittent Porphyria: A Case Report.
Transplantation proceedings, , Volume: 51, Issue:1

ORAL CONTRACEPTIVES AND ACUTE INTERMITTENT PORPHYRIA.
Lancet (London, England), , Jan-30, Volume: 1, Issue:7379, 1965

Methotrexate and actinomycin D chemotherapy in a patient with porphyria: a case report.
Journal of medical case reports, , Jan-18, Volume: 10, 2016

Differential regulation of human ALAS1 mRNA and protein levels by heme and cobalt protoporphyrin.
Molecular and cellular biochemistry, , Volume: 319, Issue:1-2, 2008

Acute intermittent porphyria: analgesia can be dangerous.
BMJ case reports, , Sep-30, Volume: 12, Issue:9, 2019

Inhibition of 5-aminolevulinic acid-induced DNA damage by melatonin, N1-acetyl-N2-formyl-5-methoxykynuramine, quercetin or resveratrol.
Journal of pineal research, , Volume: 38, Issue:2, 2005

[Anesthetic management of a patient with acute intermittent porphyria].
Masui. The Japanese journal of anesthesiology, , Volume: 42, Issue:12, 1993

Initial presentation of undiagnosed acute intermittent porphyria as a rare complication of ovulation induction.
Fertility and sterility, , Volume: 86, Issue:2, 2006

Alterations of the redox state, pentose pathway and glutathione metabolism in an acute porphyria model. Their impact on heme pathway.
Experimental biology and medicine (Maywood, N.J.), , Volume: 238, Issue:2, 2013

[Fatal postoperative crisis in acute hereditary porphyria].
La Tunisie medicale, , Volume: 80, Issue:5, 2002

ACUTE INTERMITTENT PORPHYRIA: THE ANAESTHETIC PROBLEM AND ITS BACKGROUND.
British journal of anaesthesia, , Volume: 36, 1964

Inhibition of 5-aminolevulinic acid-induced DNA damage by melatonin, N1-acetyl-N2-formyl-5-methoxykynuramine, quercetin or resveratrol.
Journal of pineal research, , Volume: 38, Issue:2, 2005

[Two cases of acute porphyria].
Japanese journal of medical science & biology, , Mar-10, Volume: 51, 1963

Management of acute and cutaneous porphyrias.
International journal of clinical practice, , Volume: 56, Issue:4, 2002

Safe usage of isotretinoin in a woman with latent acute intermittent porphyria.
Acta dermato-venereologica, , Volume: 87, Issue:3, 2007

Medical termination of pregnancy in acute intermittent porphyria.
Gynecologic and obstetric investigation, , Volume: 62, Issue:1, 2006

Use of propofol anesthesia and adjunctive treatment with levetiracetam and gabapentin in managing status epilepticus in a patient of acute intermittent porphyria.
Epilepsia, , Volume: 49, Issue:5, 2008

Levetiracetam in porphyric status epilepticus: a case report.
Clinical neuropharmacology, , Volume: 28, Issue:5

Sirolimus tolerability in a kidney transplant recipient with acute intermittent porphyria.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, , Volume: 17, Issue:6, 2002

Gabapentin reduces neurovisceral pain of porphyria.
Acta neurologica Taiwanica, , Volume: 19, Issue:2, 2010

[Morphine for pain treatment in a patient wih acute intermittent porphyria].
Anasthesiologie, Intensivmedizin, Notfallmedizin, Schmerztherapie : AINS, , Volume: 36, Issue:2, 2001

Safe usage of bicalutamide and goserelin in a male patient with acute intermittent porphyria and prostate cancer.
Scandinavian journal of urology, , Volume: 53, Issue:2-3

Case 38-2021: A 76-Year-Old Woman with Abdominal Pain, Weight Loss, and Memory Impairment.
The New England journal of medicine, , Dec-16, Volume: 385, Issue:25, 2021

Exhumation examination to confirm suspicion of fatal lead poisoning.
Forensic science international, , May-10, Volume: 158, Issue:2-3, 2006

The effect of therapeutic drugs and other pharmacologic agents on activity of porphobilinogen deaminase, the enzyme that is deficient in intermittent acute porphyria.
Life sciences, , Volume: 65, Issue:2, 1999

Mass spectrometric characterisation of a condensation product between porphobilinogen and indolyl-3-acryloylglycine in urine of patients with acute intermittent porphyria.
Journal of mass spectrometry : JMS, , Volume: 50, Issue:7, 2015

Organophosphate insecticide poisoning with monocrotophos-induced fabricated illness in a 7-year-old girl with refractory seizures over a 4-year period.
Paediatrics and international child health, , Volume: 42, Issue:2, 2022

A study of 24-hour ambulatory blood pressure monitoring in cases of intermittent acute porphyria with hypertension: special reference to safety and efficacy of angiotensin-converting enzyme inhibitor (enalapril) therapy.
Indian heart journal, , Volume: 54, Issue:6

ELEVATION OF THE SERUM PROTEIN-BOUND IODINE IN ACUTE INTERMITTENT PORPHYRIA.
The Journal of clinical endocrinology and metabolism, , Volume: 23, 1963

Proteasomal degradation regulates expression of porphobilinogen deaminase (PBGD) mutants of acute intermittent porphyria.
Biochimica et biophysica acta, , Volume: 1762, Issue:9, 2006

Eslicarbazepine for focal epilepsy and acute intermittent porphyria.
Epileptic disorders : international epilepsy journal with videotape, , Jun-01, Volume: 22, Issue:3, 2020

Biochemical characterization of porphobilinogen deaminase-deficient mice during phenobarbital induction of heme synthesis and the effect of enzyme replacement.
Molecular medicine (Cambridge, Mass.), , Volume: 9, Issue:9-12

Anticancer therapy in patients with porphyrias: evidence today.
Expert opinion on drug safety, , Volume: 7, Issue:2, 2008

Serum erythropoietin levels may be inappropriately low in the acute neuropsychiatric porphyrias.
Clinica chimica acta; international journal of clinical chemistry, , Volume: 317, Issue:1-2, 2002

Acute intermittent porphyria: A rare cause of syndrome of inappropriate antidiuretic hormone secretion.
The journal of the Royal College of Physicians of Edinburgh, , Volume: 53, Issue:2, 2023

A mysterious case with abdominal pain and syndrome of inappropriate anti-diuretic hormone secretion.
The Turkish journal of pediatrics, , Volume: 62, Issue:3, 2020

Severe hyponatremia due to SIADH provoked by acute intermittent porphyria.
Clinical nephrology, , Volume: 45, Issue:6, 1996

TRANSIENT EXCESS URINARY EXCRETION OF ANTIDIURETIC MATERIAL IN ACUTE INTERMITTENT PORPHYRIA WITH HYPONATREMIA AND HYPOMAGNESEMIA.
The American journal of medicine, , Volume: 38, 1965

EXCESS URINARY EXCRETION OF ANTIDIURETIC MATERIAL IN ACUTE INTERMITTENT PORPHYRIA WITH HYPONATREMIA.
Acta neurologica Scandinavica, , Volume: 40, Issue:2, 1964

Hyponatremia in acute intermittent porphyria probably resulting from inappropriate secretion of antidiuretic hormone.
Annals of the New York Academy of Sciences, , Mar-05, Volume: 104, 1963

Abnormal electrolyte and water metabolism in acute intermittent porphyria. The transient inappropriate secretion of antidiuretic hormone.
The American journal of medicine, , Volume: 32, 1962

[Treatment of acute porphyria with cytochrome c].
Medizinische Klinik, , Jan-20, Volume: 56, 1961

Glucose metabolism during fasting is altered in experimental porphobilinogen deaminase deficiency.
Human molecular genetics, , Apr-01, Volume: 25, Issue:7, 2016

Two new mutations in the porphobilinogen deaminase gene and a screening method using PCR amplification of specific alleles.
Human genetics, , Volume: 93, Issue:1, 1994

Systemic inflammation in acute intermittent porphyria: a case-control study.
Clinical and experimental immunology, , Volume: 187, Issue:3, 2017

LIPIDS IN THE BRAIN IN ACUTE PORPHYRIA.
Acta medica Polona, , Volume: 4, 1963

[ON THE TREATMENT OF ACUTE INTERMITTEN PORPHYRIA].
Folia haematologica (Leipzig, Germany : 1928), , Volume: 81, 1963

[On the treatment of acute intermittent porphyria].
Orvosi hetilap, , Jun-23, Volume: 104, 1963

Clinical characteristic of psychiatric symptoms in Acute Intermittent Porphyria (AIP): A report of a pair of identical twins.
Asian journal of psychiatry, , Volume: 29, 2017

Premenstrual attacks of acute intermittent porphyria: hormonal and metabolic aspects - a case report.
European journal of endocrinology, , Volume: 141, Issue:1, 1999

Two patients with acute intermittent porphyria treated with nafarelin to prevent menstrual exacerbations.
Journal of the Royal Society of Medicine, , Volume: 93, Issue:8, 2000

Remifentanil and acute intermittent porphyria.
European journal of anaesthesiology, , Volume: 19, Issue:11, 2002

Anticancer therapy in patients with porphyrias: evidence today.
Expert opinion on drug safety, , Volume: 7, Issue:2, 2008

Hyperhomocysteinemia in patients with acute porphyrias: a possible effect of ALAS1 modulation by siRNAm therapy and its control by vitamin supplementation.
European journal of internal medicine, , Volume: 92, 2021

Hyperhomocysteinemia in patients with acute porphyrias: A potentially dangerous metabolic crossroad?
European journal of internal medicine, , Volume: 79, 2020

Preliminary report: hyperhomocysteinemia in patients with acute intermittent porphyria.
Metabolism: clinical and experimental, , Volume: 59, Issue:12, 2010

ACUTE INTERMITTENT PORPHYRIA.
The Journal of the Medical Society of New Jersey, , Volume: 61, 1964

[ON THE TREATMENT OF ACUTE INTERMITTEN PORPHYRIA].
Folia haematologica (Leipzig, Germany : 1928), , Volume: 81, 1963

[On the treatment of acute intermittent porphyria].
Orvosi hetilap, , Jun-23, Volume: 104, 1963

Immunosuppressive therapy for acute porphyria: safety and efficacy in a patient with bone marrow failure.
Pharmacotherapy, , Volume: 26, Issue:11, 2006

Renal transplantation in a case of acute intermittent porphyria.
Journal of clinical pharmacology, , Volume: 43, Issue:10, 2003

Pretransplant evaluation of a patient with acute intermittent porphyria.
Progress in transplantation (Aliso Viejo, Calif.), , Volume: 11, Issue:3, 2001

The tolerability of newer immunosuppressive medications in a patient with acute intermittent porphyria.
Journal of clinical pharmacology, , Volume: 41, Issue:1, 2001

Is 5-aminolevulinic acid involved in the hepatocellular carcinogenesis of acute intermittent porphyria?
Cellular and molecular biology (Noisy-le-Grand, France), , Volume: 48, Issue:1, 2002

5-Aminolevulinic acid mediates the in vivo and in vitro formation of 8-hydroxy-2'-deoxyguanosine in DNA.
Carcinogenesis, , Volume: 15, Issue:10, 1994

DNA alkylation by 4,5-dioxovaleric acid, the final oxidation product of 5-aminolevulinic acid.
Chemical research in toxicology, , Volume: 11, Issue:2, 1998

Hepatocellular carcinoma in patients from northern Sweden with acute intermittent porphyria: morphology and mutations.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, , Volume: 5, Issue:5, 1996

Acute intermittent porphyria caused by a G to C mutation in exon 12 of the porphobilinogen deaminase gene that results in exon skipping.
Human genetics, , Volume: 92, Issue:6, 1993

[Clinical manifestations of porphyrin metabolism disorders].
Terapevticheskii arkhiv, , Volume: 75, Issue:7, 2003

Hyperhomocysteinemia in patients with acute porphyrias: a possible effect of ALAS1 modulation by siRNAm therapy and its control by vitamin supplementation.
European journal of internal medicine, , Volume: 92, 2021

Dysregulation of homocysteine homeostasis in acute intermittent porphyria patients receiving heme arginate or givosiran.
Journal of inherited metabolic disease, , Volume: 44, Issue:4, 2021

Preliminary report: hyperhomocysteinemia in patients with acute intermittent porphyria.
Metabolism: clinical and experimental, , Volume: 59, Issue:12, 2010

[A case of acute idiopathic porphyria in a 8 year old].
La Pediatria, , Volume: 59, Issue:9-10

[Porphyria].
Ryoikibetsu shokogun shirizu, , Issue:40, 2003

Is 5-aminolevulinic acid involved in the hepatocellular carcinogenesis of acute intermittent porphyria?
Cellular and molecular biology (Noisy-le-Grand, France), , Volume: 48, Issue:1, 2002

5-Aminolevulinic acid mediates the in vivo and in vitro formation of 8-hydroxy-2'-deoxyguanosine in DNA.
Carcinogenesis, , Volume: 15, Issue:10, 1994

Synonyms(7)

Research

Studies (437)

Protein Targets (0)

Acute Porphyria

Synonyms(7)

Research

Studies (437)

Drugs Studied (220)

Protein Targets (0)