Androgenization

Development of male secondary SEX CHARACTERISTICS in the FEMALE. It is due to the effects of androgenic metabolites of precursors from endogenous or exogenous sources, such as ADRENAL GLANDS or therapeutic drugs.

Synonym
Androgenization
Virilization
Virilism

Excerpt	Reference
"Virilism is the major manifestation in children (83 percent of the cases), either isolated or associated with hypercortisolism and/or feminization."	( Benaily, M; Job, JC; Schweisguth, O, 1975)
"Virilization is usually associated with amenorrhea, infertility and ovarian stromal lesions."	( DeSanctis, VM; Rivera-Alsina, ME; Schmidt, WA, 1987)
"Virilization is associated with either ovarian causes, including polycystic ovary syndrome, hyperthecosis, and ovarian tumor, or with adrenal causes, including tumors and congenital adrenal hyperplasia."	( Alagöl, F; Azizlerli, H; Dizdaroglu, F; Tanakol, R; Terzioğlu, T, 1997)
"In this young girl, virilization is due to concomitant ectopic and intra-adrenal adenomas of the adrenal cortex."	( Bettendorf, M; Beuschlein, F; Choukair, D; Haufe, S; Holland-Cunz, S; Wudy, SA; Zwermann, O, 2013)
"Virilism is a female disorder in which secondary male sexual characteristics develop, caused by an excessive adrenal or ovarian androgen secretion."	( Benavent Correro, P; García Cano, A; Jiménez Mendiguchia, L; Luque-Ramírez, M; Moreno Moreno, E; Sáenz Valls, M, 2018)

Excerpt	Reference
"Treatment of virilization symptoms in 230 patients is reported."	( Grund, E; Schmidt-Elmendorff, H, 1975)
"(2) Medical therapy for the virilization is successful."	( Baylis, BW; Corenblum, B, 1990)
"Six patients with post-menopausal virilization and increase in 17-hydroxyprogesterone (17-OHP), total (TT) and free testosterone (FT) levels underwent single subcutaneous administration of goserelin, 3."	( Bertagna, A; Brocato, L; Di Bisceglie, C; Ghigo, E; Gianotti, L; Manieri, C; Tagliabue, M, 2003)
"As the patient refused surgery, virilization was treated with the antiandrogen cyproterone acetate (CPA), but for only 4 months because clinical and hormone abnormalities reversed and the tumor was no longer visible."	( Benvenga, S; Campennì, A; Lasco, A; Maglitto, D; Morini, E, 2005)
"There was a significant reduction in virilization in the DEX-treated group (WMD: -2."	( Cai, L; Chen, G; Huang, H; Li, L; Liang, J; Lin, W; Wang, N; Wen, J; Xu, L; Zong, L, 2020)
"Prenatal DEX treatment reduced virilization with no significant differences in newborn physical outcomes, cognitive functions, behavioural problems and temperament."	( Cai, L; Chen, G; Huang, H; Li, L; Liang, J; Lin, W; Wang, N; Wen, J; Xu, L; Zong, L, 2020)

Timeframe	Studies, This Condition (%)	All Conditions %
pre-1990	642 (60.57)	23.3326
1990's	112 (10.57)	12.5806
2000's	123 (11.60)	18.1394
2010's	142 (13.40)	28.8240
2020's	41 (3.87)	9.53

Drug	Relationship Strength	Studies	Trials
gamma-aminobutyric acid	low	1	0
benzene	low	1	0
salicylic acid	low	1	0
creatine	low	1	0
glycine	low	1	0
inositol	low	1	0
uric acid	low	2	0
urea	low	1	0
3,4-methylenedioxyamphetamine	low	1	0
phenytoin	low	2	0
aminoglutethimide	low	5	0
amobarbital	low	1	0
anastrozole	low	1	0
aspirin	low	1	0
cyproheptadine	low	2	0
diazoxide	low	1	0
valproic acid	low	1	0
fluorouracil	low	1	0
flutamide	low	1	0
glutethimide	low	2	0
guaifenesin	low	1	0
hydroxyurea	low	1	0
ketoconazole	low	5	0
labetalol	low	1	0
letrozole	low	1	0
metformin	low	1	0
metyrapone	medium	11	1
minoxidil	low	1	0
mitotane	low	10	0
phenylbutazone	low	1	0
saccharin	low	1	0
thioridazine	low	1	0
tolbutamide	low	1	0
trifluoperazine	low	1	0
urethane	low	1	0
hydrocortisone acetate	low	1	0
corticosterone	low	6	0
prednisolone	low	9	0
estriol	low	8	0
thymidine	low	1	0
thyroxine	low	1	0
norethindrone acetate	low	1	0
spironolactone	low	4	0
aldosterone	low	17	0
lynestrenol	low	2	0
norethandrolone	low	2	0
tetrahydrocortisol	low	1	0
prednisone	medium	23	1
estrone	low	12	0
oxandrolone	medium	6	1
androsterone	low	24	0
etiocholanolone	low	10	0
dehydroepiandrosterone	medium	92	1
pilocarpine	low	1	0
carbon tetrachloride	low	1	0
desoxycorticosterone acetate	low	2	0
chloramphenicol	low	1	0
ethinyl estradiol	medium	22	2
testosterone propionate	medium	13	1
methyltestosterone	medium	12	1
leucine	low	2	0
androstenedione	low	74	0
methionine	low	2	0
desoxycorticosterone	low	4	0
norethindrone	medium	15	1
norethynodrel	low	4	0
17-alpha-hydroxyprogesterone	low	42	0
cytarabine	low	1	0
histidine	low	1	0
medroxyprogesterone acetate	low	3	0
mestranol	low	6	0
dichlorodiphenyldichloroethane	low	6	0
methandrostenolone	low	6	0
quinoxalines	low	1	0
phenothiazine	low	1	0
acetophenone	low	1	0
pregnenolone	low	12	0
dydrogesterone	medium	1	1
cyclopentane	low	1	0
oxazoles	low	2	0
ethynodiol diacetate	low	1	0
hydrazine	low	1	0
chlormadinone acetate	low	3	0
nandrolone decanoate	medium	1	1
cyproterone acetate	medium	14	2
nandrolone	medium	17	3
hydantoins	low	1	0
epitestosterone	low	1	0
medroxyprogesterone	low	10	0
androstenediol	low	1	0
dihydrotestosterone	low	36	0
algestone	low	1	0
dehydroepiandrosterone sulfate	medium	31	1
levonorgestrel	low	1	0
boldenone	low	1	0
ethylestrenol	low	3	0
testolactone	medium	2	1
megestrol	medium	1	1
n-methylaspartate	low	1	0
fluorine	low	1	0
chlorine	low	1	0
chlorine dioxide	low	1	0
trolamine salicylate	low	1	0
stanozolol	low	5	0
fluorides	low	1	0
danazol	low	6	0
daunorubicin	low	1	0
phenyl acetate	low	3	0
triamcinolone	low	1	0
fludrocortisone	low	4	0
pregnanolone	low	1	0
androstane-3,17-diol	low	7	0
glutamic acid	low	2	0
methyldopa	low	2	0
vinclozolin	low	2	0
desogestrel	low	1	0
sufentanil	low	1	0
buserelin	low	2	0
3-iodobenzylguanidine	low	1	0
testosterone undecanoate	low	2	0
metaperiodate	low	1	0
tetrahydro-11-deoxycortisol	low	1	0
trenbolone acetate	low	3	0
triazoles	low	1	0
fluorodeoxyglucose f18	low	2	0
adosterol	low	5	0
17-alpha-hydroxypregnenolone	low	11	0
testosterone isobutyrate	low	1	0
pregnanetriol	low	31	0
16-hydroxydehydroepiandrosterone	low	1	0
2,3-bis(4-hydroxyphenyl)-propionitrile	low	1	0
cobalt	low	1	0
fulvestrant	low	1	0
cyproterone acetate, ethinyl estradiol drug combination	low	3	0
11-hydroxyandrostenedione	low	1	0
docetaxel anhydrous	low	1	0
androsterone sulfate	low	1	0
testololactone	medium	1	1
17-hydroxypregnanolone	low	1	0
estradiol 3-benzoate	low	2	0
cortisone	low	30	0
allylestrenol	low	2	0
2-hydroxyestradiol	low	1	0
pregnanetriolone	low	1	0
carboplatin	low	1	0
glycogen	low	1	0
oxytocin	low	1	0
cortodoxone	medium	6	1
tibolone	low	1	0
diethylstilbestrol	low	3	0
gamma-sitosterol	low	1	0
bromochloroacetic acid	low	5	0
leuprolide	low	9	0
mercaptopurine	low	1	0
enclomiphene	low	6	0
thiourea	low	1	0
tamoxifen	low	2	0
nadp	low	1	0
zinc oxide	low	1	0
androstane-3,17-diol glucuronide	low	2	0
methenolone	medium	4	2
cytellin	low	1	0
fg 9041	low	1	0
17-ketosteroids	medium	183	1
quercetin	low	1	0
bilirubin	low	1	0
alprostadil	low	1	0
stigmasterol	low	1	0
oxymetholone	medium	10	2
lutein	low	1	0
cyproterone	medium	28	3
ethisterone	low	3	0
meprednisone	medium	1	1
methylestrenolone	low	1	0
morphine	low	1	0
beta-funaltrexamine	low	1	0
goserelin	low	1	0
ly2066948	low	1	0
naltrexone	low	1	0
norbinaltorphimine	low	1	0
dizocilpine maleate	low	1	0
pregnanediol	low	16	0
11 beta-hydroxyandrosterone	low	2	0
losartan potassium	low	3	0
pituitrin	low	1	0
clove	low	1	0
acid phosphatase	low	1	0
nad	low	1	0
cosyntropin	low	4	0
dynorphins	low	1	0
adrenocorticotropin zinc	low	1	0
gastrins	low	1	0
glucagon	low	1	0
thymosin beta(4)	low	1	0
neuropeptide y	low	1	0
19-iodocholesterol	low	1	0
menotropins	low	2	0
bucladesine	low	1	0
sodium ethylxanthate	low	3	0
trelstar	low	3	0
cetrorelix	low	1	0
nafarelin	medium	1	1
piperidines	low	1	0
thymosin	low	1	0
vasoactive intestinal peptide	low	1	0
transforming growth factor beta	low	2	0
kiss1 protein, human	low	1	0
rome	low	1	0
bassianolide	low	1	0
norgestrel	low	1	0
thromboplastin	low	1	0
sildenafil citrate	low	1	0
leptin	low	2	0
phenanthrenes	low	1	0

Protein Targets (1,243)

Protein	Potency Measurements	Inhibition Measurements	Activation Measurements	Drugs
Glucose-6-phosphate 1-dehydrogenase	0	6	0	6
Chain A, Cruzipain	7	0	0	7
IDH1	18	0	0	18
DNA polymerase iota isoform a (long)	21	0	0	21
geminin	64	0	0	64
Sex hormone-binding globulin	0	1	25	26
acetylcholinesterase	18	0	0	18
pregnane X receptor	20	0	0	20
SMAD family member 2	22	0	0	22
SMAD family member 3	22	0	0	22
TDP1 protein	76	0	0	76
GLI family zinc finger 3	63	0	0	63
Microtubule-associated protein tau	26	0	0	26
AR protein	93	0	0	93
progesterone receptor	58	0	0	58
glucocorticoid receptor [Homo sapiens]	81	0	0	81
retinoic acid nuclear receptor alpha variant 1	65	0	0	65
retinoid X nuclear receptor alpha	53	0	0	53
estrogen-related nuclear receptor alpha	69	0	0	69
farnesoid X nuclear receptor	36	0	0	36
pregnane X nuclear receptor	67	0	0	67
estrogen nuclear receptor alpha	93	0	0	93
G	41	0	0	41
vitamin D (1,25- dihydroxyvitamin D3) receptor	42	0	0	42
arylsulfatase A	15	0	0	15
euchromatic histone-lysine N-methyltransferase 2	47	0	0	47
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a	55	0	0	55
activating transcription factor 6	22	0	0	22
nuclear receptor subfamily 1, group I, member 2	17	0	0	17
chromobox protein homolog 1	38	0	0	38
nuclear factor erythroid 2-related factor 2 isoform 1	55	0	0	55
survival motor neuron protein isoform d	22	0	0	22
histone acetyltransferase KAT2A isoform 1	19	0	0	19
lamin isoform A-delta10	47	0	0	47
Voltage-dependent calcium channel gamma-2 subunit	31	0	0	31
Interferon beta	52	0	0	52
HLA class I histocompatibility antigen, B alpha chain	41	0	0	41
Glucocorticoid receptor	0	41	4	51
Glycine receptor subunit alpha-1	0	40	0	40
Corticosteroid-binding globulin	0	19	0	20
Adenosine receptor A3	0	21	0	21
Replicase polyprotein 1ab	0	4	2	6
Androgen receptor	0	63	1	65
Alpha-1B adrenergic receptor	0	24	0	24
Glutamate receptor 2	31	4	1	39
Glycine receptor subunit beta	0	40	0	40
Glycine receptor subunit alpha-2	0	40	0	40
Glycine receptor subunit alpha-3	0	40	0	40
Mitogen-activated protein kinase 3	0	1	0	1
Alpha-1A adrenergic receptor	0	23	0	23
Sodium-dependent dopamine transporter	0	24	0	24
TAR DNA-binding protein 43	18	0	0	18
Inositol hexakisphosphate kinase 1	41	0	0	41
cytochrome P450 2C9, partial	41	0	0	41
ATP-dependent phosphofructokinase	16	0	0	16
Chain A, TYROSYL-DNA PHOSPHODIESTERASE	20	0	0	20
Chain A, Putative fructose-1,6-bisphosphate aldolase	9	0	0	9
Chain A, JmjC domain-containing histone demethylation protein 3A	11	0	0	11
Chain A, 2-oxoglutarate Oxygenase	11	0	0	11
Luciferase	14	0	0	14
glp-1 receptor, partial	16	0	0	16
thioredoxin reductase	31	0	0	31
phosphopantetheinyl transferase	20	0	0	20
GLS protein	18	0	0	18
Hsf1 protein	0	0	2	3
thioredoxin glutathione reductase	8	0	0	8
Smad3	14	0	0	14
apical membrane antigen 1, AMA1	7	0	0	7
hypothetical protein, conserved	3	0	0	3
bromodomain adjacent to zinc finger domain 2B	13	0	0	13
pyruvate kinase	2	0	0	2
glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase	0	1	0	1
lysosomal alpha-glucosidase preproprotein	4	0	0	4
glucose-6-phosphate 1-dehydrogenase isoform b	0	1	0	1
fructose-bisphosphate aldolase A	1	0	0	1
parathyroid hormone/parathyroid hormone-related peptide receptor precursor	15	0	0	15
pyruvate kinase PKM isoform a	1	0	0	1
DNA polymerase beta	6	0	0	6
mitogen-activated protein kinase 1	13	0	0	13
flap endonuclease 1	9	0	0	9
ras-related protein Rab-9A	5	0	0	5
serine/threonine-protein kinase PLK1	3	0	0	3
urokinase-type plasminogen activator precursor	10	0	0	10
plasminogen precursor	10	0	0	10
urokinase plasminogen activator surface receptor precursor	10	0	0	10
nuclear receptor ROR-gamma isoform 1	17	0	0	17
DNA dC->dU-editing enzyme APOBEC-3G isoform 1	3	0	0	3
Estrogen receptor	0	36	11	51
Endothelin receptor type B	1	1	0	2
Endothelin-1 receptor	1	0	0	1
Disabled homolog 2-interacting protein	0	1	0	1
Estrogen receptor beta	0	14	9	24
Adenylate cyclase type 10	0	1	0	1
hypothetical protein CAALFM_CR05890CA	0	0	0	1
H3 histone acetyltransferase	0	0	0	1
large T antigen	0	1	0	1
Cytochrome P450 2C9	0	10	1	11
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE	27	0	0	27
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)	13	0	0	13
nuclear factor erythroid 2-related factor 2 isoform 2	20	0	0	20
dopamine D1 receptor	2	0	0	2
Thrombopoietin	4	0	0	4
cytochrome P450 2D6 isoform 1	6	0	0	6
cytochrome P450 2C19 precursor	9	0	0	9
lethal factor (plasmid)	18	0	0	18
POU domain, class 2, transcription factor 1	0	0	0	1
Spike glycoprotein	24	0	2	26
5-hydroxytryptamine receptor 2C	0	3	2	5
5-hydroxytryptamine receptor 2A	0	6	2	8
5-hydroxytryptamine receptor 1A	0	11	1	12
Sodium-dependent noradrenaline transporter	0	30	0	30
Sodium-dependent dopamine transporter	0	2	1	3
5-hydroxytryptamine receptor 1B	0	9	1	10
5-hydroxytryptamine receptor 1D	0	0	1	1
5-hydroxytryptamine receptor 1F	0	0	1	1
5-hydroxytryptamine receptor 2B	0	3	2	5
5-hydroxytryptamine receptor 6	0	0	1	1
Sodium-dependent serotonin transporter	0	33	1	34
Sodium-dependent serotonin transporter	0	4	1	5
5-hydroxytryptamine receptor 7	0	1	1	2
5-hydroxytryptamine receptor 5A	0	0	1	1
5-hydroxytryptamine receptor 5B	0	0	1	1
5-hydroxytryptamine receptor 3A	0	0	1	1
5-hydroxytryptamine receptor 4	0	0	1	1
5-hydroxytryptamine receptor 3B	0	0	1	1
Polyphenol oxidase 2	0	4	0	6
3-alpha-hydroxysteroid dehydrogenase	0	0	0	1
Glycogen synthase kinase-3 beta	0	3	0	3
thyroid hormone receptor beta isoform a	20	0	0	20
Mineralocorticoid receptor	0	7	4	12
Mineralocorticoid receptor	0	2	0	2
Solute carrier organic anion transporter family member 1A1	0	5	0	7
Guanine nucleotide-binding protein G	7	0	0	7
thyroid hormone receptor beta isoform 2	59	0	0	59
peroxisome proliferator activated receptor gamma	41	0	0	41
ATP-binding cassette sub-family C member 3	0	29	0	29
Multidrug resistance-associated protein 4	0	30	0	32
Bile salt export pump	0	49	0	49
Cellular tumor antigen p53	49	0	0	49
Thromboxane-A synthase	0	5	0	5
Prostaglandin E2 receptor EP3 subtype	0	1	0	1
Prostaglandin E2 receptor EP4 subtype	0	1	1	2
Prostaglandin E2 receptor EP1 subtype	0	1	0	1
Prostacyclin receptor	0	1	1	2
Nuclear receptor subfamily 4 group A member 2	0	0	1	1
Solute carrier organic anion transporter family member 2A1	0	0	0	1
Nuclear receptor subfamily 4 group A member 2	0	0	1	1
Nuclear receptor subfamily 4 group A member 2	0	0	1	1
Prostaglandin E2 receptor EP2 subtype	0	1	1	2
Canalicular multispecific organic anion transporter 1	0	28	0	28
Solute carrier organic anion transporter family member 2A1	0	0	0	1
Solute carrier organic anion transporter family member 2B1	0	1	0	1
Solute carrier organic anion transporter family member 3A1	0	0	0	1
cytochrome P450 family 3 subfamily A polypeptide 4	43	0	0	43
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a	27	0	0	27
peripheral myelin protein 22 isoform 1	13	0	0	13
potassium voltage-gated channel subfamily H member 2 isoform d	17	0	0	17
transcriptional regulator ERG isoform 3	13	0	0	13
peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	9	0	0	9
cytochrome P450 3A4 isoform 1	30	0	0	30
Gamma-aminobutyric acid receptor subunit pi	30	6	0	36
Sterol O-acyltransferase 1	0	1	0	1
Cholesterol side-chain cleavage enzyme, mitochondrial	0	1	0	1
Triosephosphate isomerase	0	1	0	1
Steroid 17-alpha-hydroxylase/17,20 lyase	0	5	0	5
Cholesterol side-chain cleavage enzyme, mitochondrial	0	1	0	1
Aromatase	0	17	0	24
Gamma-aminobutyric acid receptor subunit beta-1	30	6	0	36
Ribosyldihydronicotinamide dehydrogenase [quinone]	0	1	0	1
Gamma-aminobutyric acid receptor subunit delta	30	6	0	36
Gamma-aminobutyric acid receptor subunit gamma-2	30	7	1	38
Gamma-aminobutyric acid receptor subunit alpha-5	30	7	0	37
Gamma-aminobutyric acid receptor subunit alpha-3	30	6	0	36
Aromatase	0	1	1	2
Gamma-aminobutyric acid receptor subunit gamma-1	30	6	0	36
Gamma-aminobutyric acid receptor subunit alpha-2	30	6	0	36
Gamma-aminobutyric acid receptor subunit alpha-4	30	6	0	36
Gamma-aminobutyric acid receptor subunit gamma-3	30	6	0	36
Cytochrome P450 11B2, mitochondrial	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-6	30	6	0	36
Delta-type opioid receptor	0	8	1	12
Gamma-aminobutyric acid receptor subunit alpha-1	30	7	1	38
Gamma-aminobutyric acid receptor subunit beta-3	30	7	0	37
Gamma-aminobutyric acid receptor subunit beta-2	30	6	1	37
GABA theta subunit	30	6	0	36
Gamma-aminobutyric acid receptor subunit epsilon	30	6	0	36
Amine oxidase [flavin-containing] A	0	2	0	2
UDP-glucuronosyltransferase 1A4	0	2	0	4
heat shock protein beta-1	23	0	0	23
Androgen receptor	0	18	6	27
Chain A, HADH2 protein	20	0	0	20
Chain B, HADH2 protein	20	0	0	20
interleukin 8	11	0	0	11
RAR-related orphan receptor gamma	58	0	0	58
aldehyde dehydrogenase 1 family, member A1	33	0	0	33
estrogen receptor 2 (ER beta)	39	0	0	39
regulator of G-protein signaling 4	16	0	0	16
nonstructural protein 1	8	0	0	8
peroxisome proliferator-activated receptor delta	40	0	0	40
Histone H2A.x	28	0	0	28
Caspase-7	8	0	0	8
Bloom syndrome protein isoform 1	15	0	0	15
caspase-3	8	0	0	8
importin subunit beta-1 isoform 1	6	0	0	6
nuclear factor NF-kappa-B p105 subunit isoform 1	3	0	0	3
snurportin-1	6	0	0	6
GTP-binding nuclear protein Ran isoform 1	3	0	0	3
peripheral myelin protein 22	27	0	0	27
muscleblind-like protein 1 isoform 1	13	0	0	13
neuropeptide S receptor isoform A	8	0	0	8
Beta-glucuronidase	0	2	0	2
Cholinesterase	0	4	0	4
Gastrin/cholecystokinin type B receptor	0	0	0	1
Testosterone 17-beta-dehydrogenase 3	0	3	0	3
Alpha-synuclein	6	6	0	12
Nuclear receptor ROR-gamma	20	0	0	20
Chain A, retinol dehydratase	0	1	0	1
v-jun sarcoma virus 17 oncogene homolog (avian)	37	0	0	37
G-protein coupled bile acid receptor 1	0	0	5	5
Chain A, Phospholipase A2 isoform 3	0	0	1	1
GTP-binding protein (rab7)	0	0	1	1
ras protein, partial	0	0	1	1
thyroid stimulating hormone receptor	23	0	0	23
EWS/FLI fusion protein	16	0	0	16
cytochrome P450 2D6	23	0	0	23
glucocerebrosidase	7	0	0	7
Rac1 protein	0	0	1	1
cell division cycle 42 (GTP binding protein, 25kDa), partial	0	0	1	1
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 1	7	0	0	7
DNA polymerase kappa isoform 1	8	0	0	8
muscarinic acetylcholine receptor M1	12	0	0	12
Prostaglandin-H2 D-isomerase	0	1	0	1
Solute carrier family 22 member 6	0	3	0	3
Prostaglandin G/H synthase 1	0	2	0	2
Prostaglandin G/H synthase 2	0	2	0	2
Epidermal growth factor receptor	0	7	0	7
Carbonic anhydrase 1	0	9	0	13
Carbonic anhydrase 2	0	11	0	16
Fatty acid-binding protein, liver	0	2	0	2
Integrin beta-3	7	1	1	9
Myeloperoxidase	0	2	0	2
Prostaglandin G/H synthase 1	0	3	0	3
Seed linoleate 13S-lipoxygenase-1	0	2	0	4
Integrin alpha-IIb	7	1	1	9
Glutathione hydrolase 1 proenzyme	0	1	0	1
Prostaglandin G/H synthase 1	0	9	0	9
Adenosine receptor A1	0	4	0	5
Adenosine receptor A2a	0	3	0	4
Substance-P receptor	0	2	0	2
Prostaglandin G/H synthase 2	0	7	0	7
Urotensin-2 receptor	0	1	0	1
4-aminobutyrate aminotransferase, mitochondrial	0	1	0	1
Ras-related protein Rab-2A	0	0	1	1
Prostaglandin G/H synthase 2	0	1	0	1
Rho-associated protein kinase 2	0	1	0	1
Nicotinate phosphoribosyltransferase	0	3	0	3
Solute carrier family 22 member 20	0	2	0	2
Solute carrier family 22 member 6	0	2	0	2
Sigma non-opioid intracellular receptor 1	0	12	1	13
Sigma non-opioid intracellular receptor 1	0	1	1	2
Chain A, Ferritin light chain	11	0	0	11
ATAD5 protein, partial	23	0	0	23
Fumarate hydratase	8	0	0	8
nuclear receptor subfamily 1, group I, member 3	49	0	0	49
polyprotein	8	0	0	8
P53	1	0	0	1
aryl hydrocarbon receptor	16	0	0	16
thyroid stimulating hormone receptor	28	0	0	28
hemoglobin subunit beta	3	0	0	3
cellular tumor antigen p53 isoform a	10	0	0	10
M-phase phosphoprotein 8	11	0	0	11
Bile salt export pump	0	7	0	7
ATPase family AAA domain-containing protein 5	19	0	0	19
Ataxin-2	24	0	0	24
Protein-arginine deiminase type-4	0	1	0	1
Chain A, Integrase	0	1	0	1
Chain A, Integrase	0	1	0	1
Chain A, T4 LYSOZYME	0	0	1	1
Chain A, GCN4P1	0	0	1	1
Chain B, GCN4P1	0	0	1	1
Chain C, GCN4P1	0	0	1	1
Chain A, T4 LYSOZYME	0	0	1	1
Chain A, T4 LYSOZYME	0	0	1	1
Chain A, Replicase polyprotein 1ab	0	1	0	1
Chain A, 3C-like proteinase	0	1	0	1
Endolysin	0	0	1	1
Muscarinic acetylcholine receptor M2	0	6	0	7
Kappa-type opioid receptor	0	6	2	9
Mu-type opioid receptor	0	17	5	27
Delta-type opioid receptor	0	13	4	22
Kappa-type opioid receptor	0	17	3	26
Mu-type opioid receptor	0	6	2	11
Inositol monophosphatase 1	10	0	0	10
USP1 protein, partial	24	0	0	24
vitamin D3 receptor isoform VDRA	18	0	0	18
caspase-1 isoform alpha precursor	1	0	0	1
Caspase-7	1	0	0	1
Solute carrier organic anion transporter family member 1B3	0	2	0	4
Solute carrier organic anion transporter family member 1B1	0	2	0	5
Angiotensin-converting enzyme	0	0	0	1
B2 bradykinin receptor	0	1	0	1
B2 bradykinin receptor	0	4	1	7
B1 bradykinin receptor	0	1	0	1
Olfactory receptor 51E2	0	0	5	5
vasopressin V1b receptor	1	0	0	1
cAMP-dependent protein kinase type I-alpha regulatory subunit	0	0	1	1
cAMP-dependent protein kinase type II-beta regulatory subunit	0	0	1	1
cAMP-dependent protein kinase catalytic subunit beta isoform 1	0	0	1	1
relaxin receptor 1 isoform 1	1	0	0	1
relaxin receptor 2 isoform 1	1	0	0	1
cAMP-dependent protein kinase catalytic subunit beta isoform 3	0	0	1	1
Cytochrome P450 2E1	0	1	0	1
histone-lysine N-methyltransferase 2A isoform 2 precursor	9	0	0	9
Gonadotropin-releasing hormone receptor	0	2	1	3
streptokinase A precursor	0	0	3	3
Dihydroxyacetone phosphate acyltransferase	0	0	0	1
30S ribosomal protein S6	0	1	0	1
30S ribosomal protein S7	0	1	0	1
50S ribosomal protein L15	0	1	0	1
Cytochrome P450 3A4	0	9	1	11
50S ribosomal protein L10	0	1	0	1
50S ribosomal protein L11	0	1	0	1
50S ribosomal protein L7/L12	0	1	0	1
50S ribosomal protein L19	0	1	0	1
50S ribosomal protein L1	0	1	0	1
50S ribosomal protein L20	0	1	0	1
50S ribosomal protein L27	0	1	0	1
50S ribosomal protein L28	0	1	0	1
50S ribosomal protein L29	0	1	0	1
50S ribosomal protein L31	0	1	0	1
50S ribosomal protein L31 type B	0	1	0	1
50S ribosomal protein L32	0	1	0	1
50S ribosomal protein L33	0	1	0	1
50S ribosomal protein L34	0	1	0	1
50S ribosomal protein L35	0	1	0	1
50S ribosomal protein L36	0	1	0	1
30S ribosomal protein S10	0	1	0	1
30S ribosomal protein S11	0	1	0	1
30S ribosomal protein S12	0	1	0	1
30S ribosomal protein S13	0	1	0	1
30S ribosomal protein S16	0	1	0	1
30S ribosomal protein S18	0	1	0	1
30S ribosomal protein S19	0	1	0	1
30S ribosomal protein S20	0	1	0	1
30S ribosomal protein S2	0	1	0	1
30S ribosomal protein S3	0	1	0	1
30S ribosomal protein S4	0	1	0	1
30S ribosomal protein S5	0	1	0	1
30S ribosomal protein S8	0	1	0	1
30S ribosomal protein S9	0	1	0	1
50S ribosomal protein L13	0	1	0	1
50S ribosomal protein L14	0	1	0	1
50S ribosomal protein L16	0	1	0	1
50S ribosomal protein L23	0	1	0	1
30S ribosomal protein S15	0	1	0	1
50S ribosomal protein L17	0	1	0	1
50S ribosomal protein L21	0	1	0	1
50S ribosomal protein L30	0	1	0	1
50S ribosomal protein L6	0	1	0	1
30S ribosomal protein S14	0	1	0	1
30S ribosomal protein S17	0	1	0	1
30S ribosomal protein S1	0	1	0	1
50S ribosomal protein L18	0	1	0	1
50S ribosomal protein L2	0	1	0	1
50S ribosomal protein L3	0	1	0	1
50S ribosomal protein L24	0	1	0	1
50S ribosomal protein L4	0	1	0	1
50S ribosomal protein L22	0	1	0	1
50S ribosomal protein L5	0	1	0	1
30S ribosomal protein S21	0	1	0	1
50S ribosomal protein L25	0	1	0	1
50S ribosomal protein L36 2	0	1	0	1
Methionine--tRNA ligase, mitochondrial	0	0	1	1
Cytochrome P450 2C19	0	9	0	9
NFKB1 protein, partial	6	0	0	6
GALC protein	8	0	0	8
serine/threonine-protein kinase mTOR isoform 1	8	0	0	8
Solute carrier family 22 member 2	0	3	0	3
Solute carrier family 22 member 1	0	8	0	8
Solute carrier family 22 member 3	0	1	0	1
Solute carrier family 22 member 3	0	2	0	2
C-8 sterol isomerase	0	4	0	4
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase	0	5	1	6
Solute carrier family 22 member 1	0	2	0	3
Solute carrier family 22 member 2	0	3	0	3
endonuclease IV	8	0	0	8
atrial natriuretic peptide receptor 1 precursor	3	0	0	3
Potassium voltage-gated channel subfamily A member 1	0	0	1	1
Multidrug and toxin extrusion protein 1	0	4	0	4
Sodium- and chloride-dependent creatine transporter 1	0	1	0	1
Proton-coupled amino acid transporter 1	0	4	0	5
PPM1D protein	7	0	0	7
D(1A) dopamine receptor	10	0	0	10
huntingtin isoform 2	6	0	0	6
atrial natriuretic peptide receptor 2 precursor	3	0	0	3
chaperonin GroEL	1	0	0	1
Polyunsaturated fatty acid lipoxygenase ALOX15B	7	1	0	8
Sodium-dependent noradrenaline transporter	0	1	0	1
5-hydroxytryptamine receptor 4	0	12	0	12
Aldo-keto reductase family 1 member B1	0	30	0	30
Muscarinic acetylcholine receptor M2	0	13	1	14
Muscarinic acetylcholine receptor M4	0	8	0	8
Muscarinic acetylcholine receptor M1	0	5	0	6
Muscarinic acetylcholine receptor M3	0	5	0	6
Muscarinic acetylcholine receptor M4	0	5	0	6
Muscarinic acetylcholine receptor M5	0	5	0	6
Muscarinic acetylcholine receptor M5	0	9	0	9
Alpha-2A adrenergic receptor	0	16	1	17
Glycogen phosphorylase, brain form	0	1	0	1
Glycogen phosphorylase, muscle form	0	1	0	1
Muscarinic acetylcholine receptor M1	0	11	2	13
Angiotensin-converting enzyme	0	8	0	8
D(2) dopamine receptor	0	8	0	8
Alpha-2B adrenergic receptor	0	14	0	14
Alpha-2C adrenergic receptor	0	12	0	12
D	0	2	0	2
D(3) dopamine receptor	0	4	0	4
Muscarinic acetylcholine receptor M3	0	12	0	12
D(1A) dopamine receptor	0	10	0	10
Endothelin receptor type B	0	1	0	1
Histamine H2 receptor	0	10	0	10
Alpha-1D adrenergic receptor	0	10	1	11
D(1B) dopamine receptor	0	2	0	2
5-hydroxytryptamine receptor 2A	0	12	0	12
5-hydroxytryptamine receptor 2C	0	12	0	12
D(4) dopamine receptor	0	2	0	2
5-hydroxytryptamine receptor 2C	0	1	0	1
5-hydroxytryptamine receptor 7	0	2	0	2
Histamine H1 receptor	0	4	1	5
D(3) dopamine receptor	0	12	0	12
UDP-glucuronosyltransferase 1A3	0	0	0	2
5-hydroxytryptamine receptor 2B	0	18	0	18
Histamine H2 receptor	12	0	0	12
5-hydroxytryptamine receptor 6	0	14	0	14
D(2) dopamine receptor	0	1	0	1
D(2) dopamine receptor	0	5	1	6
Potassium voltage-gated channel subfamily H member 2	0	12	0	12
Sodium-dependent serotonin transporter	0	1	0	1
Nuclear receptor subfamily 3 group C member 3	0	8	0	8
Histone-lysine N-methyltransferase SETD7	0	2	0	2
Transporter	0	1	0	1
Chain A, Beta-lactamase	14	0	0	14
67.9K protein	13	0	0	13
Progesterone receptor	0	12	6	19
Adenosine receptor A2b	0	1	0	1
ORF73	0	0	1	1
LMP1 [Human herpesvirus 4]	0	0	0	2
nuclear receptor coactivator 1 isoform 1 [Homo sapiens]	0	1	0	1
transactivating tegument protein VP16 [Human herpesvirus 1]	0	1	0	1
nuclear receptor coactivator 3 isoform a	0	1	0	1
Thymidine kinase 2, mitochondrial	0	1	0	1
Thymidine kinase, cytosolic	0	3	0	5
Thymidine kinase	0	2	0	3
Thymidylate synthase	0	1	0	3
Thymidine kinase	0	1	0	1
Deoxycytidine kinase	0	0	0	1
Probable deoxycytidylate deaminase	0	0	0	1
Cytidine deaminase	0	1	0	2
D(1A) dopamine receptor	3	0	0	3
E3 ubiquitin-protein ligase Mdm2	0	1	0	1
Enoyl-[acyl-carrier-protein] reductase [NADH]	0	1	0	1
Thymidine kinase	0	1	0	2
Deoxynucleoside kinase	0	1	0	1
hypoxia-inducible factor 1 alpha subunit	22	0	0	22
Rap guanine nucleotide exchange factor 3	7	0	0	7
Cytochrome P450 1A2	0	5	0	5
Beta-3 adrenergic receptor	0	6	1	7
Substance-K receptor	0	10	0	10
Cytochrome P450 2J2	0	4	0	4
Chain A, Breast cancer type 1 susceptibility protein	1	0	0	1
Chain A, ATP-DEPENDENT DNA HELICASE Q1	3	0	0	3
caspase 7, apoptosis-related cysteine protease	11	0	0	11
caspase-3	11	0	0	11
runt-related transcription factor 1 isoform AML1b	2	0	0	2
core-binding factor subunit beta isoform 2	2	0	0	2
Transthyretin	0	2	0	3
NADH-ubiquinone oxidoreductase chain 4	0	0	0	1
ATP-dependent translocase ABCB1	0	11	2	14
72 kDa type IV collagenase	0	2	0	2
DNA topoisomerase 2-alpha	0	0	0	1
Carbonyl reductase [NADPH] 1	0	0	0	1
Glutamate receptor 1	1	4	1	9
Glutamate receptor 3	1	4	1	9
Glutamate receptor 4	1	4	1	9
Platelet-activating factor receptor	1	0	0	1
Multidrug resistance-associated protein 1	0	3	0	5
Histone deacetylase 1	0	4	0	4
Reverse transcriptase/RNaseH	0	1	0	1
Histone deacetylase 8	0	4	0	4
Histone deacetylase 6	0	4	0	4
Broad substrate specificity ATP-binding cassette transporter ABCG2	0	4	1	6
Beta-glucuronidase	0	1	0	1
Glucose-6-phosphate 1-dehydrogenase	0	1	0	1
NPC1-like intracellular cholesterol transporter 1	0	0	1	1
Solute carrier organic anion transporter family member 1A4	0	0	0	2
Solute carrier organic anion transporter family member 1A5	0	0	0	2
Steryl-sulfatase	0	2	0	3
Solute carrier organic anion transporter family member 1A2	0	0	0	2
Solute carrier organic anion transporter family member 1A3	0	0	0	2
ATP-binding cassette sub-family C member 11	0	0	0	1
Solute carrier family 22 member 11	0	0	0	1
Solute carrier organic anion transporter family member 1A1	0	0	0	1
Solute carrier organic anion transporter family member 1B2	0	0	0	1
Coagulation factor VII	0	1	0	1
Tissue factor	0	2	0	2
Nicotinamide phosphoribosyltransferase	0	0	1	1
ATP-binding cassette sub-family C member 8	0	1	1	2
ATP-sensitive inward rectifier potassium channel 11	0	1	1	2
Peroxisome proliferator-activated receptor alpha	2	0	0	2
15-lipoxygenase, partial	8	0	0	8
ubiquitin carboxyl-terminal hydrolase 2 isoform a	4	0	0	4
high affinity choline transporter 1 isoform a	0	1	0	1
Nuclear receptor subfamily 1 group I member 2	0	1	3	4
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1	0	3	0	3
Tyrosine-protein kinase Fyn	0	6	0	6
Beta-1 adrenergic receptor	0	6	1	7
Polyunsaturated fatty acid 5-lipoxygenase	0	5	0	5
Polyunsaturated fatty acid lipoxygenase ALOX15	0	8	0	8
Acetylcholinesterase	0	4	0	4
Adenosine receptor A2a	0	6	0	6
Adenosine receptor A1	0	4	0	4
Vasopressin V1a receptor	0	4	1	5
Estrogen-related receptor gamma	0	1	1	2
Disintegrin and metalloproteinase domain-containing protein 17	3	0	0	3
Aldehyde oxidase	0	2	0	4
UDP-glucose 4-epimerase	0	1	0	1
Mitogen-activated protein kinase 14	0	2	0	2
Cysteinyl leukotriene receptor 1	0	2	0	2
Chain A, Sex Hormone-Binding Globulin	0	0	1	1
thyrotropin-releasing hormone receptor	2	0	0	2
Plasma kallikrein	0	1	0	2
Progesterone receptor	0	1	0	1
Glucocorticoid receptor	0	2	1	3
Sex hormone-binding globulin	0	1	0	1
Androgen receptor	0	1	3	4
Angiotensin-converting enzyme	0	0	1	1
Cannabinoid receptor 2	0	1	0	1
Muscarinic acetylcholine receptor	0	1	0	1
Neuropeptide FF receptor 2	0	0	0	2
ALK tyrosine kinase receptor	0	2	0	2
Glutamate receptor ionotropic, NMDA 1	0	9	3	15
Glutamate receptor ionotropic, NMDA 2A	0	9	3	15
Glutamate receptor ionotropic, NMDA 2B	0	9	3	15
Glutamate receptor ionotropic, NMDA 2C	0	9	3	15
Glutamate receptor ionotropic, NMDA 2D	0	9	3	15
Glutamate receptor ionotropic, NMDA 3B	0	9	3	15
Glutamate receptor ionotropic, NMDA 3A	0	9	3	15
Serum paraoxonase/arylesterase 1	0	1	0	1
Kinesin-like protein KIF11	0	1	0	1
Nucleotide-binding oligomerization domain-containing protein 2	0	1	0	1
Mas-related G-protein coupled receptor member X2	0	0	2	2
chaperonin-containing TCP-1 beta subunit homolog	2	0	0	2
ubiquitin-conjugating enzyme E2 N	0	2	0	2
protein AF-9 isoform a	0	0	0	1
Receptor tyrosine-protein kinase erbB-2	0	2	0	2
Cytochrome P450 2D6	0	7	0	8
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)	4	0	0	4
serine-protein kinase ATM isoform a	3	0	0	3
Estrogen receptor	0	1	3	5
Estrogen receptor beta	0	0	3	4
UDP-glucuronosyltransferase 2B7	0	2	0	4
Lanosterol 14-alpha demethylase	0	0	1	1
UDP-glucuronosyltransferase 1A10	0	0	0	1
hexokinase-4 isoform 1	1	0	0	1
glucokinase regulatory protein	1	0	0	1
17-beta-hydroxysteroid dehydrogenase type 1	0	2	0	3
Mu-type opioid receptor	0	8	3	15
Mu-type opioid receptor	0	6	2	10
Cytochrome P450 1B1	0	3	1	4
Ghrelin O-acyltransferase	0	1	0	1
Vpr	3	0	0	3
Cytochrome P450 2B1	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-4	1	0	0	1
Neuronal acetylcholine receptor subunit beta-2	1	0	0	1
Cytochrome P450 2B6	0	2	0	2
UDP-glucuronosyltransferase 1A1	0	4	0	6
3-oxo-5-alpha-steroid 4-dehydrogenase 1	0	1	0	1
Sulfotransferase 1A1	0	2	1	4
Nuclear receptor subfamily 1 group I member 3	0	1	0	1
Multidrug and toxin extrusion protein 2	0	1	0	1
mu-type opioid receptor isoform MOR-1	0	0	1	1
5-hydroxytryptamine receptor 2A	0	0	1	1
Amine oxidase [flavin-containing] A	0	3	0	3
Chain H, IGG1-KAPPA DB3 FAB (HEAVY CHAIN)	0	1	0	1
Chain L, IGG1-KAPPA DB3 FAB (LIGHT CHAIN)	0	1	0	1
Chain H, IGG1-KAPPA DB3 FAB (HEAVY CHAIN)	0	1	0	1
Chain L, IGG1-KAPPA DB3 FAB (LIGHT CHAIN)	0	1	0	1
Chain H, IGG1-KAPPA DB3 FAB (HEAVY CHAIN)	0	1	0	1
Chain L, IGG1-KAPPA DB3 FAB (LIGHT CHAIN)	0	1	0	1
ClpP	1	0	0	1
Chain A, GLUTAMATE RECEPTOR SUBUNIT 2	0	2	0	2
Chain A, Glutamate Receptor Subunit 2	0	2	0	2
Chain B, Glutamate Receptor Subunit 2	0	2	0	2
fatty acid synthase	0	1	0	1
Glycoprotein hormones alpha chain	2	0	0	2
Glutamate receptor ionotropic, kainate 1	0	3	1	5
Glutamate receptor ionotropic, kainate 2	0	3	1	5
Glutamate receptor 1	0	4	1	5
Glutamate receptor 2	0	4	1	5
Glutamate receptor 3	0	3	1	4
Glutamate receptor ionotropic, kainate 3	0	3	0	4
Glutamate receptor 4	0	4	1	5
Glutamate receptor ionotropic, kainate 4	0	3	0	4
Glutamate receptor ionotropic, kainate 5	0	3	0	4
Carbonic anhydrase 4	0	6	0	8
Carbonic anhydrase	0	1	0	2
Carbonic anhydrase 15	0	2	0	3
Chain A, Uracil Phosphoribosyltransferase	0	1	0	1
Skn7p	0	0	0	1
Solute carrier family 22 member 8	0	0	0	2
Amyloid-beta precursor protein	1	2	0	3
HSP40, subfamily A [Plasmodium falciparum 3D7]	0	0	0	1
alpha-galactosidase	1	0	0	1
cytochrome P450 2C9 precursor	6	0	0	6
Cocaine esterase	0	2	0	3
Arylacetamide deacetylase	0	0	0	1
Arylacetamide deacetylase	0	0	0	1
Arylacetamide deacetylase	0	0	0	1
Steroid hormone receptor ERR1	0	2	0	2
Bifunctional epoxide hydrolase 2	0	3	0	3
Beta-lactamase TEM	0	1	0	1
Bile acid receptor	0	2	0	2
NAD-dependent protein deacylase sirtuin-5, mitochondrial	0	2	0	2
Gamma-aminobutyric acid	0	1	2	3
Gamma-aminobutyric acid receptor subunit rho-3	0	0	1	1
Gamma-aminobutyric acid receptor subunit pi	0	3	0	3
Gamma-aminobutyric acid receptor subunit delta	0	3	0	3
Histone deacetylase 3	0	3	0	3
Gamma-aminobutyric acid type B receptor subunit 2	0	0	1	1
Gamma-aminobutyric acid type B receptor subunit 2	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-1	0	3	1	4
Gamma-aminobutyric acid receptor subunit alpha-6	0	1	2	3
Gamma-aminobutyric acid receptor subunit beta-1	0	3	1	4
Gamma-aminobutyric acid receptor subunit gamma-2	0	3	1	4
Gamma-aminobutyric acid receptor subunit gamma-2	0	1	2	3
Gamma-aminobutyric acid receptor subunit delta	0	1	2	3
Sodium- and chloride-dependent GABA transporter 1	0	3	0	3
Gamma-aminobutyric acid receptor subunit rho-1	0	0	2	2
Gamma-aminobutyric acid receptor subunit alpha-2	0	1	2	3
Gamma-aminobutyric acid receptor subunit alpha-3	0	1	2	3
Gamma-aminobutyric acid receptor subunit gamma-3	0	1	2	3
Gamma-aminobutyric acid receptor subunit beta-3	0	3	1	4
Gamma-aminobutyric acid receptor subunit rho-2	0	0	1	1
Sodium- and chloride-dependent GABA transporter 1	0	1	0	1
Sodium- and chloride-dependent taurine transporter	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-5	0	3	1	4
Sodium- and chloride-dependent GABA transporter 2	0	3	0	3
Sodium- and chloride-dependent GABA transporter 3	0	3	0	3
Sodium- and chloride-dependent GABA transporter 1	0	1	0	1
Sodium- and chloride-dependent GABA transporter 2	0	2	0	2
Sodium- and chloride-dependent GABA transporter 3	0	2	0	2
Gamma-aminobutyric acid receptor subunit alpha-3	0	3	1	4
Gamma-aminobutyric acid receptor subunit alpha-2	0	3	1	4
Gamma-aminobutyric acid receptor subunit beta-2	0	3	1	4
Sodium- and chloride-dependent betaine transporter	0	3	0	3
Sodium- and chloride-dependent betaine transporter	0	1	0	1
Sodium- and chloride-dependent GABA transporter 3	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-4	0	3	1	4
Gamma-aminobutyric acid receptor subunit beta-1	0	1	2	3
Histone deacetylase 4	0	3	0	3
Gamma-aminobutyric acid receptor subunit alpha-1	0	2	2	4
Gamma-aminobutyric acid receptor subunit beta-3	0	1	2	3
Gamma-aminobutyric acid receptor subunit epsilon	0	3	0	3
4-aminobutyrate aminotransferase, mitochondrial	0	0	0	1
4-aminobutyrate aminotransferase, mitochondrial	0	0	0	1
Gamma-aminobutyric acid receptor subunit alpha-6	0	3	1	4
Sterol O-acyltransferase 1	0	0	1	1
Gamma-aminobutyric acid receptor subunit alpha-5	0	1	2	3
Gamma-aminobutyric acid receptor subunit gamma-1	0	3	0	3
Gamma-aminobutyric acid receptor subunit pi	0	1	2	3
Histone deacetylase 7	0	3	0	3
Histone deacetylase 2	0	3	0	3
Polyamine deacetylase HDAC10	0	3	0	3
Histone deacetylase 11	0	3	0	3
Gamma-aminobutyric acid receptor subunit gamma-3	0	3	0	3
Gamma-aminobutyric acid receptor subunit alpha-4	0	1	2	3
Platelet glycoprotein VI	0	0	1	1
Gamma-aminobutyric acid receptor subunit theta	0	1	2	3
Sodium- and chloride-dependent GABA transporter 2	0	1	0	1
Gamma-aminobutyric acid receptor subunit gamma-1	0	1	2	3
Gamma-aminobutyric acid type B receptor subunit 1	0	0	1	1
Histone deacetylase 9	0	3	0	3
Gamma-aminobutyric acid receptor subunit theta	0	3	0	3
Histone deacetylase 5	0	3	0	3
Gamma-aminobutyric acid type B receptor subunit 1	0	1	0	1
Chain A, Slr1257 protein	0	0	1	1
Chain A, Glucosamine--fructose-6-phosphate aminotransferase [isomerizing]	0	1	0	1
beta-2 adrenergic receptor	1	0	0	1
Metabotropic glutamate receptor 8	0	2	0	2
Metabotropic glutamate receptor 6	0	1	1	3
Glutamate receptor ionotropic, NMDA 2D	0	1	0	1
Excitatory amino acid transporter 4	0	1	0	1
Glutamate receptor ionotropic, NMDA 3B	0	1	0	1
Glutathione reductase, mitochondrial	0	3	0	3
Bifunctional aspartokinase/homoserine dehydrogenase 1	0	1	0	1
Prothrombin	0	1	2	3
ATP-citrate synthase	0	1	0	1
Metabotropic glutamate receptor 1	0	1	1	2
Metabotropic glutamate receptor 2	0	0	1	1
Metabotropic glutamate receptor 3	0	0	1	1
Metabotropic glutamate receptor 4	0	1	1	2
Metabotropic glutamate receptor 5	0	0	1	1
Metabotropic glutamate receptor 6	0	0	1	1
Metabotropic glutamate receptor 7	0	0	1	1
Glutamate receptor ionotropic, kainate 1	0	1	1	2
Metabotropic glutamate receptor 5	0	1	1	3
Excitatory amino acid transporter 1	0	2	0	3
Excitatory amino acid transporter 2	0	2	0	3
Excitatory amino acid transporter 3	0	2	0	3
Metabotropic glutamate receptor 8	0	0	1	1
Excitatory amino acid transporter 3	0	0	0	1
Glutamate racemase	0	0	0	1
Metabotropic glutamate receptor 8	0	1	1	2
Fatty-acid amide hydrolase 1	0	1	0	1
Glutamate carboxypeptidase 2	0	1	0	1
Glutamate receptor ionotropic, NMDA 1	0	1	0	1
Glutamate receptor ionotropic, NMDA 2A	0	1	0	1
Glutamate receptor ionotropic, kainate 2	0	1	1	2
Glutamate receptor ionotropic, kainate 3	0	1	0	1
Glutamate receptor ionotropic, NMDA 2B	0	1	0	1
Metabotropic glutamate receptor 1	0	1	1	3
Metabotropic glutamate receptor 2	0	1	1	3
Metabotropic glutamate receptor 7	0	1	1	3
Metabotropic glutamate receptor 3	0	1	1	3
Metabotropic glutamate receptor 4	0	1	1	3
Glutamate receptor ionotropic, NMDA 2C	0	1	0	1
Glutamate receptor ionotropic, kainate 5	0	1	0	1
Carbonic anhydrase-like protein, putative	0	0	0	2
Glutamate racemase	0	0	0	1
Prolyl 4-hydroxylase	0	1	0	1
Glutamate receptor ionotropic, NMDA 3A	0	1	0	1
Alpha-ketoglutarate-dependent dioxygenase FTO	0	1	0	1
Glycine receptor subunit alpha-1	0	0	1	1
Sodium- and chloride-dependent glycine transporter 1	0	1	0	1
Large neutral amino acids transporter small subunit 1	0	4	0	4
Serine racemase	0	1	0	1
Sodium- and chloride-dependent glycine transporter 2	0	1	0	1
Chain A, HISTIDINE-BINDING PROTEIN	0	0	1	1
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN	0	0	1	1
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN	0	0	1	1
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN	0	0	1	1
Carbonic anhydrase 12	0	3	0	5
Carbonic anhydrase 3	0	3	0	5
Histidine-binding periplasmic protein	0	0	1	1
Carbonic anhydrase 6	0	3	0	5
5-hydroxytryptamine receptor 1D	0	0	0	1
Carbonic anhydrase 5A, mitochondrial	0	5	0	7
Carbonic anhydrase 7	0	3	0	5
Carbonic anhydrase	0	1	0	2
Glutaminyl-peptide cyclotransferase	0	1	0	1
Carbonic anhydrase 9	0	5	0	8
Carbonic anhydrase	0	0	0	1
Carbonic anhydrase	0	0	0	1
Carbonic anhydrase	0	1	0	2
Carbonic anhydrase	0	0	0	1
Carbonic anhydrase 13	0	0	0	1
Carbonic anhydrase 4	0	0	0	1
Carbonic anhydrase 13	0	2	0	4
Carbonic anhydrase 14	0	3	0	5
Carbonic anhydrase 5B, mitochondrial	0	3	0	5
Glycogen synthase kinase-3 alpha	0	2	0	2
Protein cereblon	0	2	0	2
Stromelysin-1	0	1	2	3
Urease subunit alpha	0	5	0	5
Ribonucleoside-diphosphate reductase large subunit	0	1	0	1
Urease subunit beta	0	5	0	5
Chain B, Pulmonary surfactant-associated protein D	0	1	0	1
Chain A, Pulmonary surfactant-associated protein D	0	1	0	1
Sodium/myo-inositol cotransporter 2	0	1	0	1
Estrogen receptor beta	0	1	0	2
25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial	0	1	0	1
25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial	0	2	0	2
Cytochrome P450 26A1	0	1	0	1
3',5'-cyclic-AMP phosphodiesterase	0	1	0	1
Camphor 5-monooxygenase	0	0	0	1
Phospholipase A2, major isoenzyme	0	1	0	1
Chymotrypsinogen A	0	2	0	2
Beta-lactamase	0	2	0	2
ATP-dependent translocase ABCB1	0	3	0	3
Epoxide hydrolase 1	0	0	0	1
Cytochrome P450 2C11	0	1	0	1
Steroid 21-hydroxylase	0	1	0	1
Cytochrome P450 2C8	0	3	0	3
Steroid 17-alpha-hydroxylase/17,20 lyase	0	1	0	1
Polyunsaturated fatty acid 5-lipoxygenase	0	3	0	3
Cholesterol side-chain cleavage enzyme, mitochondrial	0	1	0	1
Indoleamine 2,3-dioxygenase 1	0	1	0	1
Cytochrome P450 2A2	0	1	0	1
Cytochrome P450 11B1, mitochondrial	0	2	0	2
Cytochrome P450 11B1, mitochondrial	0	3	0	3
Translocator protein	0	1	1	2
Cytochrome P450 7A1	0	1	0	1
Cytochrome P450 11B2, mitochondrial	0	3	0	3
Estrogen receptor	0	1	0	2
ATP-dependent translocase ABCB1	0	3	0	3
Gonadotropin-releasing hormone receptor	0	3	1	4
Type-1 angiotensin II receptor	0	1	0	1
Malate dehydrogenase, cytoplasmic	0	1	0	1
Cytochrome P450 4F2	0	1	0	1
1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial	0	2	0	2
1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial	0	1	0	1
Sodium/bile acid cotransporter	0	1	0	1
Lanosterol 14-alpha demethylase	0	4	1	5
Cytochrome P450 7A1	0	1	0	1
Lanosterol 14-alpha demethylase	0	2	0	2
Beta-1 adrenergic receptor	0	0	1	1
Beta-2 adrenergic receptor	0	2	1	3
Alpha-2B adrenergic receptor	0	1	1	2
Alpha-2C adrenergic receptor	0	1	1	2
Alpha-2A adrenergic receptor	0	1	1	2
Alpha-1A adrenergic receptor	0	0	1	1
Alpha-1B adrenergic receptor	0	0	1	1
Beta-2 adrenergic receptor	0	1	1	2
Heparanase	0	0	1	1
Chain A, AMINOPEPTIDASE	0	1	0	1
Chain A, AMINOPEPTIDASE	0	1	0	1
Chain A, Leucine Aminopeptidase	0	1	0	1
Alkaline phosphatase, tissue-nonspecific isozyme	0	1	0	1
Intestinal-type alkaline phosphatase	0	1	0	1
Phospholipase A-2-activating protein	0	1	0	1
Type-1A angiotensin II receptor	0	1	0	1
Type-1B angiotensin II receptor	0	2	0	2
Type-2 angiotensin II receptor	0	1	0	1
cGMP-inhibited 3',5'-cyclic phosphodiesterase B	0	1	0	1
cGMP-inhibited 3',5'-cyclic phosphodiesterase A	0	1	0	1
5-hydroxytryptamine receptor 1A	0	1	0	1
Type-1 angiotensin II receptor	0	1	0	1
retinoic acid receptor alpha isoform 1	0	1	0	1
retinoic acid receptor RXR-alpha isoform a	0	1	0	1
Chain A, Estrogen receptor	0	1	0	1
PINK1	2	0	0	2
Parkin	5	0	0	5
Aldo-keto reductase family 1 member C3	0	1	0	1
Aldo-keto reductase family 1 member C2	0	1	0	1
Aldo-keto reductase family 1 member C1	0	1	0	1
UDP-glucose 6-dehydrogenase	0	1	0	1
Hypoxanthine-guanine phosphoribosyltransferase	0	0	0	1
UDP-glucose 6-dehydrogenase	0	1	0	1
Purine nucleoside phosphorylase	0	0	1	1
UDP-glucuronosyltransferase 1A1	0	1	0	1
cystic fibrosis transmembrane conductance regulator ATP-binding cassette sub-family C member 7	0	0	0	1
Cannabinoid receptor 1	0	4	0	4
Dihydrofolate reductase	0	1	0	1
Dipeptidyl peptidase 4	0	2	0	2
Chain A, Methionyl-tRNA synthetase	0	0	1	1
Chain A, Methionyl-tRNA synthetase	0	0	1	1
Chain A, Aminopeptidase	0	1	0	1
Chain A, Methionine aminopeptidase	0	1	0	1
S-ribosylhomocysteine lyase	0	1	0	1
Adenylate cyclase type 5	0	0	0	1
S-adenosylmethionine synthase isoform type-1	0	0	0	1
S-adenosylmethionine synthase isoform type-2	0	0	0	1
Fatty acid synthase	0	1	0	1
Caspase 6, apoptosis-related cysteine peptidase	0	0	0	1
estrogen receptor beta isoform 1	0	1	0	1
DNA polymerase eta isoform 1	3	0	0	3
Cystathionine gamma-lyase	0	2	0	2
Solute carrier family 15 member 1	0	1	0	1
phosphoglycerate kinase	2	0	0	2
2,3-bisphosphoglycerate-independent phosphoglycerate mutase	1	0	0	1
Nuclear receptor subfamily 1 group I member 2	0	0	1	1
Cytochrome P450 11B1, mitochondrial	0	2	0	2
lethal(3)malignant brain tumor-like protein 1 isoform I	1	0	0	1
Rap guanine nucleotide exchange factor 4	2	0	0	2
Opioid receptor, delta 1b	0	1	0	1
Acetylcholinesterase	0	1	0	1
Opioid receptor homologue	0	1	0	1
Acyl-CoA desaturase 1	0	1	0	1
Histidine decarboxylase	0	0	2	2
Proteinase-activated receptor 1	0	1	1	2
Delta-type opioid receptor	0	7	2	11
Kappa-type opioid receptor	0	6	2	9
Kappa-type opioid receptor	0	6	0	8
Nociceptin receptor	0	1	0	1
5-hydroxytryptamine receptor 7	0	2	0	2
Mu-type opioid receptor	0	1	0	1
Mu-type opioid receptor	0	1	0	1
Chain B, Exotoxin A	0	0	1	1
Chain B, Exotoxin A	0	0	1	1
Chain B, Exotoxin A	0	0	1	1
5-hydroxytryptamine receptor 3E	0	1	0	1
5-hydroxytryptamine receptor 3B	0	1	0	1
Nociceptin receptor	0	2	0	2
5-hydroxytryptamine receptor 3A	0	1	0	1
5-hydroxytryptamine receptor 3D	0	1	0	1
5-hydroxytryptamine receptor 3C	0	1	0	1
UDP-glucuronosyltransferase 1A8	0	0	0	1
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial	0	1	0	1
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial	0	1	0	1
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 3, mitochondrial	0	1	0	1
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial	0	1	0	1
Neuropeptide Y receptor type 1	0	2	0	2
Neuropeptide Y receptor type 2	0	2	0	2
Renin	0	1	0	1
Choline O-acetyltransferase	0	1	0	1
Corticotropin-releasing factor receptor 1	0	0	0	1
Serine/threonine-protein kinase mTOR	0	1	0	1
Mitogen-activated protein kinase 8	0	0	1	1
Mitogen-activated protein kinase 9	0	0	1	1
Mitogen-activated protein kinase 10	0	1	1	2
Sodium channel protein type 1 subunit alpha	0	1	0	1
Sodium channel protein type 2 subunit alpha	0	2	0	2
Sodium channel protein type 3 subunit alpha	0	1	0	1
Vasopressin V2 receptor	0	2	1	3
Oxytocin receptor	0	2	2	4
Vasopressin V1a receptor	0	1	0	1
Vasopressin V1b receptor	0	1	1	2
Vasopressin V1b receptor	0	1	0	1
Oxytocin receptor	0	1	0	1
Oxytocin receptor	0	0	1	1
Vasopressin V2 receptor	0	1	0	1
NADPH oxidase 1	0	2	0	2
Snq2p	0	0	0	3
polyunsaturated fatty acid lipoxygenase ALOX12	2	0	0	2
rac GTPase-activating protein 1 isoform a	0	1	0	1
Pleiotropic ABC efflux transporter of multiple drugs	0	3	0	6
Prostaglandin G/H synthase 2	0	3	0	3
Prostaglandin G/H synthase 1	0	3	0	3
Estrogen receptor 1	0	1	0	1
fMet-Leu-Phe receptor	0	1	0	1
Cyclooxygenase-2	0	1	0	1
Solute carrier family 22 member 8	0	3	0	3
Voltage-dependent L-type calcium channel subunit alpha-1C	0	2	0	2
Voltage-dependent L-type calcium channel subunit alpha-1F	0	2	0	2
Dihydrofolate reductase	0	1	0	1
Aldo-keto reductase family 1 member B1	0	2	0	2
Sodium channel protein type 1 subunit alpha	0	1	0	1
Sodium channel protein type 4 subunit alpha	0	1	0	2
Voltage-dependent L-type calcium channel subunit alpha-1D	0	2	0	2
Voltage-dependent L-type calcium channel subunit alpha-1S	0	2	0	2
Voltage-dependent L-type calcium channel subunit alpha-1C	0	2	0	2
Sodium channel protein type 5 subunit alpha	0	2	0	2
Sodium channel protein type 9 subunit alpha	0	1	0	1
Sodium channel protein type 2 subunit alpha	0	1	0	1
Sodium channel protein type 3 subunit alpha	0	1	0	1
Tyrosine-protein kinase Lck	0	2	1	3
Cytochrome P450 2A6	0	2	1	3
Muscarinic acetylcholine receptor M1	0	0	1	1
Muscarinic acetylcholine receptor DM1	0	1	0	1
Cytochrome P450 2A13	0	1	1	2
luciferase	0	0	0	1
Glucocorticoid receptor	0	0	1	1
Glutamine synthetase	0	0	1	1
Histamine H1 receptor	0	0	1	1
Nociceptin receptor	0	0	1	1
Gamma-aminobutyric acid receptor subunit alpha-1	0	0	0	1
Gamma-aminobutyric acid receptor subunit beta-1	0	0	0	1
Gamma-aminobutyric acid receptor subunit alpha-2	0	0	0	1
Gamma-aminobutyric acid receptor subunit alpha-3	0	0	0	1
Gamma-aminobutyric acid receptor subunit alpha-4	0	0	0	1
Gamma-aminobutyric acid receptor subunit gamma-2	0	0	0	1
Chain A, (3R)-hydroxymyristoyl-acyl carrier protein dehydratase	0	1	0	1
Chain B, (3R)-hydroxymyristoyl-acyl carrier protein dehydratase	0	1	0	1
Chain A, (3R)-hydroxymyristoyl-acyl carrier protein dehydratase	0	1	0	1
Chain B, (3R)-hydroxymyristoyl-acyl carrier protein dehydratase	0	1	0	1
Chain A, (3R)-hydroxymyristoyl-acyl carrier protein dehydratase	0	1	0	1
Chain B, (3R)-hydroxymyristoyl-acyl carrier protein dehydratase	0	1	0	1
Chain A, APH(2')-Id	0	1	0	1
glucose-6-phosphate dehydrogenase	0	1	0	1
Nrf2	1	0	0	1
signal transducer and activator of transcription 6, interleukin-4 induced	1	0	0	1
DNA polymerase III, partial	2	0	0	2
Neuraminidase	0	2	0	2
hexokinase	0	1	0	1
Spike glycoprotein	0	0	2	2
Replicase polyprotein 1ab	0	0	2	2
galactokinase	1	0	0	1
interferon gamma precursor	0	0	0	2
histone deacetylase 9 isoform 3	1	0	0	1
tyrosine-protein kinase Yes	1	0	0	1
Transmembrane protease serine 2	0	0	2	2
Maltase-glucoamylase, intestinal	0	1	0	1
NUAK family SNF1-like kinase 1	0	1	0	1
Lysine-specific histone demethylase 1A	0	1	0	1
B2 bradykinin receptor	0	1	0	1
G2/mitotic-specific cyclin-B2	0	1	0	1
Arginase	0	1	0	1
Pancreatic triacylglycerol lipase	0	1	0	1
Prothrombin	0	1	0	1
Urokinase-type plasminogen activator	0	1	0	1
Cationic trypsin	0	1	0	1
Chymotrypsin-like elastase family member 1	0	1	0	1
Protein E6	0	1	0	1
Neuraminidase	0	1	0	1
Interstitial collagenase	0	1	1	2
Phospholipase A2	0	1	0	1
Cytochrome P450 1A1	0	2	1	3
Beta-lactamase	0	1	0	1
Cyclin-dependent kinase 1	0	1	0	1
Glycogen phosphorylase, liver form	0	1	0	1
Epoxide hydrolase 1	0	1	0	1
Trypsin-1	0	1	0	1
Trypsin-2	0	1	0	1
Procathepsin L	0	0	2	2
Tyrosine-protein kinase Yes	0	1	0	1
Proto-oncogene tyrosine-protein kinase receptor Ret	0	1	0	1
Insulin-like growth factor 1 receptor	0	1	0	1
Neutrophil elastase	0	2	0	2
Hepatocyte growth factor receptor	0	1	0	1
5-hydroxytryptamine receptor 1A	0	0	1	1
Heterogeneous nuclear ribonucleoprotein A1	0	0	1	1
Enoyl-[acyl-carrier-protein] reductase [NADH] FabI	0	1	0	1
Replicase polyprotein 1a	0	0	2	2
Replicase polyprotein 1ab	0	0	2	2
Replicase polyprotein 1ab	0	2	2	4
Calmodulin-1	0	1	1	2
Alpha-amylase 1A	0	1	0	1
Lysosomal alpha-glucosidase	0	1	0	1
Sialidase	0	1	0	1
Malate dehydrogenase	0	1	0	1
Solute carrier family 2, facilitated glucose transporter member 2	0	1	0	1
Serine/threonine-protein kinase pim-1	0	1	1	2
Cyclin-dependent kinase 4	0	1	0	1
Proto-oncogene tyrosine-protein kinase Src	0	1	0	1
Cystic fibrosis transmembrane conductance regulator	0	0	1	1
Sucrase-isomaltase, intestinal	0	1	0	1
G2/mitotic-specific cyclin-B1	0	1	0	1
Tyrosinase	0	1	0	1
Matrix metalloproteinase-9	0	1	0	1
Serine/threonine-protein kinase B-raf	0	1	0	1
Aldo-keto reductase family 1 member B1	0	2	0	2
G2/mitotic-specific cyclin-B	0	1	0	1
Polyunsaturated fatty acid lipoxygenase ALOX15	0	1	0	1
Chymotrypsinogen B	0	1	0	1
Tyrosine-protein phosphatase non-receptor type 1	0	2	0	4
Polyunsaturated fatty acid lipoxygenase ALOX12	0	1	0	1
Glycogen synthase kinase-3 beta	0	1	0	1
Solute carrier family 2, facilitated glucose transporter member 4	0	1	0	1
Casein kinase II subunit alpha'	0	2	0	2
Amine oxidase [flavin-containing] A	0	1	0	1
5'-nucleotidase	0	1	0	1
D(4) dopamine receptor	0	5	0	5
Glyceraldehyde-3-phosphate dehydrogenase, glycosomal	0	1	0	1
G1/S-specific cyclin-D1	0	1	0	1
Cyclin-dependent kinase 2	0	1	0	1
C-X-C chemokine receptor type 1	0	1	0	1
Amine oxidase [flavin-containing] B	0	1	0	1
Phosphatidylinositol 3-kinase regulatory subunit alpha	0	1	0	1
Proteasome subunit beta type-5	0	1	0	1
Cytosol aminopeptidase	0	1	0	1
ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1	0	1	0	1
Nitric oxide synthase, inducible	0	1	0	1
Tyrosine-protein kinase receptor UFO	0	1	0	1
RAC-alpha serine/threonine-protein kinase	0	1	0	1
Trypsin-3	0	1	0	1
Vascular endothelial growth factor receptor 2	0	1	0	1
Receptor-type tyrosine-protein kinase FLT3	0	1	0	1
17-beta-hydroxysteroid dehydrogenase type 2	0	1	0	1
Macrophage metalloelastase	0	1	0	1
Glutathione reductase	0	1	0	1
Tyrosine-protein kinase SYK	0	1	1	2
Collagenase 3	0	1	0	1
1-deoxy-D-xylulose 5-phosphate reductoisomerase	0	1	0	1
Xanthine dehydrogenase/oxidase	0	2	0	2
Prolyl endopeptidase	0	1	0	1
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	0	1	0	1
Aldo-keto reductase family 1 member A1	0	1	0	1
Aldo-keto reductase family 1 member A1	0	2	0	2
C-C chemokine receptor type 4	0	1	0	1
Serine/threonine-protein kinase Nek2	0	1	0	1
Oligo-1,6-glucosidase IMA1	0	1	0	1
Serine/threonine-protein kinase PLK1	0	1	0	1
Death-associated protein kinase 1	0	1	0	1
Monocarboxylate transporter 1	0	1	0	1
Amine oxidase [flavin-containing] B	0	1	0	1
Beta-secretase 1	0	2	0	2
Anthrax toxin receptor 2	0	1	0	1
Casein kinase II subunit beta	0	2	0	2
Casein kinase II subunit alpha	0	2	0	2
Lactoperoxidase	0	1	0	1
Aldo-keto reductase family 1 member B1	0	1	0	1
Xanthine dehydrogenase/oxidase	0	3	0	4
Cyclin-dependent kinase 6	0	1	0	1
Cyclin-dependent-like kinase 5	0	1	0	1
Heat shock factor protein 1	0	1	0	1
Sorbitol dehydrogenase	0	1	0	1
Cyclin homolog	0	1	0	1
cGMP-dependent 3',5'-cyclic phosphodiesterase	0	1	0	1
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B	0	1	0	1
Dual specificity mitogen-activated protein kinase kinase 1	0	1	0	1
Lactoylglutathione lyase	0	2	0	2
Focal adhesion kinase 1	0	1	0	1
Calcium/calmodulin-dependent protein kinase type II subunit beta	0	1	0	1
ELAV-like protein 3	0	1	0	1
Cyclin-dependent kinase 5 activator 1	0	1	0	1
ELAV-like protein 1	0	1	0	1
Serine/threonine-protein kinase N1	0	1	0	1
Probable maltase-glucoamylase 2	0	1	0	1
Carbonic anhydrase 3	0	1	0	1
Monocarboxylate transporter 2	0	1	0	1
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C	0	1	0	1
Substance-K receptor	0	1	0	1
Integrase	0	1	0	1
Casein kinase II subunit alpha 3	0	2	0	2
Inositol polyphosphate multikinase	0	1	0	1
G2/mitotic-specific cyclin-B3	0	1	0	1
Aldo-keto reductase family 1 member C21	0	2	0	2
Enoyl-acyl-carrier protein reductase	0	2	0	2
3-oxoacyl-acyl-carrier protein reductase	0	1	0	1
Beta-hydroxyacyl-ACP dehydratase precursor (Fatty acid synthesis protein)	0	1	0	1
Aurora kinase B	0	1	0	1
Chymotrypsin-C	0	1	0	1
Angiotensin-converting enzyme 2	0	0	2	2
Cyclin-dependent kinase 1	0	1	0	1
Phosphodiesterase	0	1	0	1
G-protein coupled receptor 35	0	1	1	2
Serine/threonine-protein kinase Nek6	0	1	0	1
NADPH oxidase 4	0	1	0	1
Hypoxia-inducible factor 1-alpha inhibitor	0	1	0	1
Dipeptidyl peptidase 3	0	1	0	1
Inositol hexakisphosphate kinase 2	0	1	0	1
Short transient receptor potential channel 5	0	1	0	1
Sialidase-2	0	1	0	1
Sphingosine kinase 2	0	2	0	2
Sphingosine kinase 1	0	1	0	1
Carbonic anhydrase	0	1	0	1
Carbonic anhydrase	0	1	0	1
Carbonic anhydrase	0	1	0	1
Carbonic anhydrase	0	1	0	1
Alpha-1D adrenergic receptor	0	3	0	3
Taste receptor type 2 member 31	0	0	1	1
Beta-carbonic anhydrase 1	0	1	0	1
Carbonic anhydrase 2	0	1	0	1
Carbonic anhydrase, alpha family	0	1	0	1
Carbonic anhydrase	0	1	0	1
Delta carbonic anhydrase	0	1	0	1
RmtA	0	1	0	1
Protein arginine N-methyltransferase 1	0	1	0	1
Inhibitor of nuclear factor kappa-B kinase subunit beta	0	0	0	1
5'-AMP-activated protein kinase subunit beta-2	0	0	0	1
Albumin	0	3	1	4
Polymerase acidic protein	0	0	2	2
Tyrosine-protein phosphatase YopH	0	1	0	1
High mobility group protein B1	0	0	1	1
Prolyl 4-hydroxylase subunit alpha-1	0	1	0	1
5'-AMP-activated protein kinase subunit gamma-1	0	0	0	1
5'-AMP-activated protein kinase catalytic subunit alpha-2	0	0	0	1
5'-AMP-activated protein kinase catalytic subunit alpha-1	0	0	0	1
Carbonic anhydrase	0	1	0	1
Solute carrier family 22 member 6	0	1	0	2
Solute carrier family 22 member 7	0	0	0	1
Ubiquitin-like domain-containing CTD phosphatase 1	0	1	0	1
5'-AMP-activated protein kinase subunit gamma-3	0	0	0	1
5'-AMP-activated protein kinase subunit gamma-2	0	0	0	1
5'-AMP-activated protein kinase subunit beta-1	0	0	0	1
cGMP-specific 3',5'-cyclic phosphodiesterase	0	1	0	1
Chain A, Mineralocorticoid receptor	0	1	0	1
Chain A, Mineralocorticoid receptor	0	1	0	1
DNA polymerase beta	0	1	0	1
Sigma non-opioid intracellular receptor 1	0	2	0	2
Chain A, CES1 protein	0	1	0	1
NPC intracellular cholesterol transporter 1 precursor	3	0	0	3
Serine/threonine-protein kinase D3	0	1	0	1
Lysosomal acid glucosylceramidase	0	0	1	1
Protein kinase C gamma type	0	1	0	1
Protein kinase C alpha type	0	2	0	2
Protein kinase C beta type	0	1	0	1
Protein kinase C delta type	0	2	0	2
Protein kinase C epsilon type	0	2	0	2
Protein kinase C zeta type	0	2	0	2
Transcriptional activator protein LuxR	0	1	0	1
Protein kinase C alpha type	0	1	0	1
Protein kinase C eta type	0	1	0	1
Substance-P receptor	0	2	0	2
Melanocortin receptor 4	0	2	0	2
Melanocortin receptor 5	0	2	0	2
Protein kinase C iota type	0	1	0	1
Melanocortin receptor 3	0	2	0	2
Protein kinase C gamma type	0	2	0	2
Protein kinase C beta type	0	2	0	2
Phospholipase D1	0	1	0	1
Protein kinase C epsilon type	0	1	0	1
Protein kinase C theta type	0	1	0	1
Protein kinase C zeta type	0	1	0	1
Protein kinase C delta type	0	1	0	1
Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform	0	1	0	1
Platelet-activating factor acetylhydrolase	0	1	0	1
Phospholipase D1	0	1	0	1
Serine/threonine-protein kinase D1	0	1	0	1
Protein kinase C eta type	0	2	0	2
Emopamil-binding protein-like	0	2	0	2
7-dehydrocholesterol reductase	0	1	1	2
Protein kinase C theta type	0	2	0	2
Albumin	0	0	3	3
Tryptophan 5-hydroxylase 1	0	1	0	1
Histamine H1 receptor	0	1	0	1
Proteasome subunit alpha type-6	0	0	1	1
Cathepsin D	0	1	0	1
Mucosa-associated lymphoid tissue lymphoma translocation protein 1	0	1	0	1
isocitrate dehydrogenase 1, partial	1	0	0	1
Alcohol dehydrogenase E chain	0	1	0	1
Alcohol dehydrogenase S chain	0	1	0	1
Urease	0	2	0	3
Urease subunit alpha	0	1	0	1
Urease subunit beta	0	1	0	1
Serine-protein kinase ATM	0	1	0	1
Serine/threonine-protein kinase ATR	0	1	0	1
Thymidine kinase	0	1	0	2
Thymidine phosphorylase	0	0	0	1
Thymidine phosphorylase	0	0	0	1
Thymidylate kinase	0	1	0	1
Thymidine kinase, cytosolic	0	0	0	2
Thymidine kinase	0	0	0	1
Thymidylate kinase	0	1	0	1
Thymidine kinase	0	1	0	2
Sterol O-acyltransferase 1	0	1	0	1
Thymidine kinase	0	0	0	1
Chain X, Thyroid hormone receptor beta-1	0	0	1	1
Chain X, Thyroid hormone receptor beta-1	0	0	1	1
Thyroid hormone receptor alpha	0	0	1	1
Thyroid hormone receptor beta	0	0	1	1
Proliferating cell nuclear antigen	0	1	0	1
Retinoic acid receptor RXR-alpha	0	0	2	2
Peroxisome proliferator-activated receptor gamma	0	0	2	2
Malate dehydrogenase, mitochondrial	0	1	0	1
Solute carrier organic anion transporter family member 4C1	0	1	0	1
Monocarboxylate transporter 8	0	0	0	1
Solute carrier organic anion transporter family member 1C1	0	0	0	1
Potassium channel subfamily K member 2	0	0	1	1
UDP-glucuronosyltransferase 1-6	0	1	0	2
UDP-glucuronosyltransferase 2B10	0	1	0	1
procathepsin L isoform 1 preproprotein	0	1	0	1
Genome polyprotein	0	1	0	1
DNA repair protein RAD52 homolog isoform a	0	0	0	1
Ubiquitin carboxyl-terminal hydrolase 1	0	1	0	1
Lysozyme C-1	0	1	0	1
Beta-glucuronidase	0	1	0	1
Trypanothione reductase	0	2	0	2
Calmodulin	0	0	1	1
DNA-dependent protein kinase catalytic subunit	0	1	0	1
Calcium-dependent protein kinase 4	0	1	0	1
WD repeat-containing protein 48	0	1	0	1
Chain A, Glycogen phosphorylase, liver form	0	0	1	1
Chain A, glycogen phosphorylase, liver form	0	0	1	1
Chain A, Glycogen phosphorylase, liver form	0	0	1	1
Chain A, Glycogen phosphorylase, liver form	0	0	1	1
Solute carrier family 2, facilitated glucose transporter member 9	0	1	1	2
Guanine deaminase	0	1	0	1
UDP-glucuronosyltransferase 1A9	0	0	0	1
Aldo-keto reductase family 1 member A1	0	1	0	1
Liver carboxylesterase 1	0	1	0	1
Aldo-keto reductase family 1 member A1	0	1	0	1
Aldo-keto reductase family 1 member B7	0	1	0	1
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Synonyms(3)

Research Excerpts

Overview

Treatment

Research

Studies (1,060)

Protein Targets (1,243)

Androgenization

Synonyms(3)

Research Excerpts

Overview

Treatment

Research

Studies (1,060)

Drugs Studied (239)

Protein Targets (1,243)