Compounds having two amino groups bonded to the same carbon, R2C(NR2)2.
ChEBI ID: 35412
| Member | Definition | Role |
|---|---|---|
| calycanthine | The principal alkaloid of the plant family Calycanthaceae. | calycanthine |
| folicanthine | folicanthine | |
| gant 61 | An aminal that is hexahydropyrimidine which is substituted on each nitrogen by a 2-(dimethylamino)benzyl group, and at the aminal carbon by a pyridin-4-yl group. A Hedgehog signaling pathway and Gli protein inhibitor. | 2-[[3-[[2-(dimethylamino)phenyl]methyl]-2-pyridin-4-yl-1,3-diazinan-1-yl]methyl]-N,N-dimethylaniline; GANT61 |
| salubrinal | A member of the class of quinolines that is a mixed aminal resulting from the formal condensation oftrichloroacetaldehyde with the amide nitrogen of trans-cinnamamide and the primary amino group of 1-quinolin-8-ylthiourea. It is a selective inhibitor of cellular complexes that dephosphorylate eukaryotic translation initiation factor 2 subunit alpha (eIF2alpha). | salubrinal |
| Timeframe | Studies, Drugs in This Class (%) | All Drugs % |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (0.50) | 18.2507 |
| 2000's | 28 (7.00) | 29.6817 |
| 2010's | 291 (72.75) | 24.3611 |
| 2020's | 79 (19.75) | 2.80 |
| Publication Type | Studies, Drugs in This Class (%) | All Drugs (%) |
|---|---|---|
| Trials | 0 (0.00%) | 5.53% |
| Reviews | 12 (2.91%) | 6.00% |
| Case Studies | 1 (0.24%) | 4.05% |
| Observational | 0 (0.00%) | 0.25% |
| Other | 400 (96.85%) | 84.16% |