Page last updated: 2024-12-11

3,5,4'-trihydroxystilbene-4'-o-glucoside

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

trans-resveratrol-4'-O-beta-D-glucopyranoside: structure in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID5322089
CHEMBL ID478753
MeSH IDM000599446

Synonyms (35)

Synonym
38963-95-0
BIDD:ER0104
resveratrol (3,4',5-trihydroxystilbene)
b-d-glucopyranoside, 4-[(e)-2-(3,5-dihydroxyphenyl)ethenyl]phenyl
(2s,3r,4s,5s,6r)-2-[4-[(e)-2-(3,5-dihydroxyphenyl)vinyl]phenoxy]-6-(hydroxymethyl)tetrahydropyran-3,4,5-triol
gob c
CHEMBL478753
(2s,3r,4s,5s,6r)-2-[4-[(e)-2-(3,5-dihydroxyphenyl)ethenyl]phenoxy]-6-(hydroxymethyl)oxane-3,4,5-triol
DTXSID60415792
trans-resveratrol 4'-o-beta-d-glucuronide
resveratroloside
trans-resveratrol-4'-o-beta-d-glucopyranoside
bdbm50478491
HY-N4195
Q17089265
CS-0032390
(2s,3r,4s,5s,6r)-2-(4-((e)-3,5-dihydroxystyryl)phenoxy)-6-(hydroxymethyl)tetrahydro-2h-pyran-3,4,5-triol
MS-26498
trans-resveratrol 4'-o-b-d-glucopyranoside
3,4,5-trihydroxystilbene 4-mono-.beta.-d-glycopyranoside
resveratrol 4-o-.beta.-d-glucopyranoside
4-((1e)-2-(3,5-dihydroxyphenyl)ethenyl)phenyl .beta.-d-glucopyranoside
4-[2-(3,5-dihydroxyphenyl)ethenyl]phenyl beta-d-glucopyranoside
.beta.-d-glucopyranoside, 4-(2-(3,5-dihydroxyphenyl)ethenyl)phenyl, (e)-
50450-48-1
.beta.-d-glucopyranoside, 4-((1e)-2-(3,5-dihydroxyphenyl)ethenyl)phenyl
beta-d-glucopyranoside, 4-(2-(3,5-dihydroxyphenyl)ethenyl)phenyl, (e)-
7dbs6rkm2s ,
resveratrol 4-o-beta-d-glucopyranoside
4-((1e)-2-(3,5-dihydroxyphenyl)ethenyl)phenyl beta-d-glucopyranoside
beta-d-glucopyranoside, 4-((1e)-2-(3,5-dihydroxyphenyl)ethenyl)phenyl
4-(2-(3,5-dihydroxyphenyl)ethenyl)phenyl beta-d-glucopyranoside
unii-7dbs6rkm2s
3,4,5-trihydroxystilbene 4-mono-beta-d-glycopyranoside
AKOS040760670
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Protein Targets (1)

Inhibition Measurements

ProteinTaxonomyMeasurementAverageMin (ref.)Avg (ref.)Max (ref.)Bioassay(s)
Polyphenol oxidase 2Agaricus bisporusIC50 (µMol)19.00000.03403.987110.0000AID1519079
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Bioassays (14)

Assay IDTitleYearJournalArticle
AID1519071Cytotoxicity against C57BL/6 mouse B16F10 cells assessed as reduction in cell viability incubated for 72 hrs by SRB assay relative to control2019European journal of medicinal chemistry, Dec-15, Volume: 184From bench to counter: Discovery and validation of a peony extract as tyrosinase inhibiting cosmeceutical.
AID336034Inhibition of bovine thymus p56LCK1993Journal of natural products, Oct, Volume: 56, Issue:10
Kinase inhibitors from Polygonum cuspidatum.
AID610400Antiinflammatory activity in human CCD-18Co cells assessed as inhibition of IL1beta-induced PGE2 production at 2.5 to 25 uM after 18 hrs2010Journal of medicinal chemistry, Oct-28, Volume: 53, Issue:20
Preventive oral treatment with resveratrol pro-prodrugs drastically reduce colon inflammation in rodents.
AID1519079Inhibition of mushroom tyrosinase using L-dopa as substrate preincubated for 10 mins followed by substrate addition and measured for 5 mins by photometric analysis2019European journal of medicinal chemistry, Dec-15, Volume: 184From bench to counter: Discovery and validation of a peony extract as tyrosinase inhibiting cosmeceutical.
AID1519070Antimelanogenic activity against C57BL/6 mouse B16F10 cells at 50 uM incubated for 72 hrs relative to control2019European journal of medicinal chemistry, Dec-15, Volume: 184From bench to counter: Discovery and validation of a peony extract as tyrosinase inhibiting cosmeceutical.
AID1519074Stability of compound in IMDM cell medium incubated for 24 hrs by HPLC analysis2019European journal of medicinal chemistry, Dec-15, Volume: 184From bench to counter: Discovery and validation of a peony extract as tyrosinase inhibiting cosmeceutical.
AID336035Inhibition of rat brain PKC1993Journal of natural products, Oct, Volume: 56, Issue:10
Kinase inhibitors from Polygonum cuspidatum.
AID1519078Ratio of IC50 for arbutin to IC50 for test compound for inhibition of mushroom tyrosinase2019European journal of medicinal chemistry, Dec-15, Volume: 184From bench to counter: Discovery and validation of a peony extract as tyrosinase inhibiting cosmeceutical.
AID1519072Drug degradation in IMDM cell medium incubated for 24 hrs by HPLC analysis2019European journal of medicinal chemistry, Dec-15, Volume: 184From bench to counter: Discovery and validation of a peony extract as tyrosinase inhibiting cosmeceutical.
AID482994Inhibition of amyloid beta 25-35 fibril formation at 10 uM by using UV-visible measurements and electron microscopy analysis2010Bioorganic & medicinal chemistry letters, Jun-01, Volume: 20, Issue:11
New stilbene dimers against amyloid fibril formation.
AID1519069Antimelanogenic activity against C57BL/6 mouse B16F10 cells at 10 uM incubated for 72 hrs relative to control2019European journal of medicinal chemistry, Dec-15, Volume: 184From bench to counter: Discovery and validation of a peony extract as tyrosinase inhibiting cosmeceutical.
AID1519073Stability of compound in DMSO at 10 mM incubated for 24 hrs by HPLC analysis2019European journal of medicinal chemistry, Dec-15, Volume: 184From bench to counter: Discovery and validation of a peony extract as tyrosinase inhibiting cosmeceutical.
AID1519068Antimelanogenic activity against C57BL/6 mouse B16F10 cells incubated for 10 to 50 uM incubated for 24 hrs2019European journal of medicinal chemistry, Dec-15, Volume: 184From bench to counter: Discovery and validation of a peony extract as tyrosinase inhibiting cosmeceutical.
AID1519077Antimelanogenic activity against C57BL/6 mouse B16F10 cells incubated for 72 hrs2019European journal of medicinal chemistry, Dec-15, Volume: 184From bench to counter: Discovery and validation of a peony extract as tyrosinase inhibiting cosmeceutical.
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (6)

TimeframeStudies, This Drug (%)All Drugs %
pre-19900 (0.00)18.7374
1990's1 (16.67)18.2507
2000's0 (0.00)29.6817
2010's5 (83.33)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 12.79

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index12.79 (24.57)
Research Supply Index1.95 (2.92)
Research Growth Index4.73 (4.65)
Search Engine Demand Index0.00 (26.88)
Search Engine Supply Index0.00 (0.95)

This Compound (12.79)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other6 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]