| Protein | Synonyms | Taxonomy |
|---|
| TGF-beta receptor type-1 | TGFR-1; EC 2.7.11.30; Activin A receptor type II-like protein kinase of 53kD; Activin receptor-like kinase 5; ALK-5; ALK5; Serine/threonine-protein kinase receptor R4; SKR4; TGF-beta type I receptor; Transforming growth factor-beta receptor type I; TGF-be | Homo sapiens (human) |
| Caspase-3 | CASP-3; EC 3.4.22.56; Apopain; Cysteine protease CPP32; CPP-32; Protein Yama; SREBP cleavage activity 1; SCA-1 | Homo sapiens (human) |
| Mitogen-activated protein kinase kinase kinase 5 | EC 2.7.11.25; Apoptosis signal-regulating kinase 1; ASK-1; MAPK/ERK kinase kinase 5; MEK kinase 5; MEKK 5 | Homo sapiens (human) |
| Mitogen-activated protein kinase 10 | MAP kinase 10; MAPK 10; EC 2.7.11.24; SAPK-beta; Stress-activated protein kinase JNK3; c-Jun N-terminal kinase 3; p54-beta | Rattus norvegicus (Norway rat) |
| Dual specificity mitogen-activated protein kinase kinase 1 | MAP kinase kinase 1; MAPKK 1; EC 2.7.12.2; ERK activator kinase 1; MAPK/ERK kinase 1; MEK 1 | Rattus norvegicus (Norway rat) |
| Mitogen-activated protein kinase 3 | MAP kinase 3; MAPK 3; EC 2.7.11.24; ERT2; Extracellular signal-regulated kinase 1; ERK-1; Insulin-stimulated MAP2 kinase; MAP kinase isoform p44; p44-MAPK; MNK1; Microtubule-associated protein 2 kinase; p44-ERK1 | Rattus norvegicus (Norway rat) |
| Mineralocorticoid receptor | MR; Nuclear receptor subfamily 3 group C member 2 | Rattus norvegicus (Norway rat) |
| cAMP-dependent protein kinase catalytic subunit alpha | PKA C-alpha; EC 2.7.11.11 | Rattus norvegicus (Norway rat) |
| Regucalcin | RC; Gluconolactonase; GNL; 3.1.1.17; Senescence marker protein 30; SMP-30 | Homo sapiens (human) |
| Calcitonin | | Homo sapiens (human) |
| Plasma membrane calcium-transporting ATPase 3 | PMCA3; EC 7.2.2.10; Plasma membrane calcium ATPase isoform 3; Plasma membrane calcium pump isoform 3 | Rattus norvegicus (Norway rat) |
| Tumor necrosis factor | Cachectin; TNF-alpha; Tumor necrosis factor ligand superfamily member 2; TNF-a | Rattus norvegicus (Norway rat) |
| Sodium/calcium exchanger 1 | Na(+)/Ca(2+)-exchange protein 1; Solute carrier family 8 member 1 | Rattus norvegicus (Norway rat) |
| Proto-oncogene tyrosine-protein kinase ROS | EC 2.7.10.1; Proto-oncogene c-Ros; Proto-oncogene c-Ros-1; Receptor tyrosine kinase c-ros oncogene 1; c-Ros receptor tyrosine kinase | Rattus norvegicus (Norway rat) |
| Calcium uniporter protein, mitochondrial | HsMCU; Coiled-coil domain-containing protein 109A | Homo sapiens (human) |
| Protein transport protein Sec16B | Leucine zipper transcription regulator 2; Regucalcin gene promoter region-related protein p117; RGPR-p117; SEC16 homolog B | Homo sapiens (human) |
| Phosphodiesterase | | Homo sapiens (human) |
| Nitric oxide synthase | | Homo sapiens (human) |
| Transcription factor p65 | | Homo sapiens (human) |
| Protein kinase C | | Homo sapiens (human) |
| G-protein coupled receptor | | Homo sapiens (human) |
| Neurofibromin | Neurofibromatosis-related protein NF-1 | Rattus norvegicus (Norway rat) |
| Ras-GTPase-activating protein SH3-domain-binding protein | | Homo sapiens (human) |
| Compound | Description |
|---|
| Nitric Oxide | A free radical gas produced endogenously by a variety of mammalian cells, synthesized from ARGININE by NITRIC OXIDE SYNTHASE. Nitric oxide is one of the ENDOTHELIUM-DEPENDENT RELAXING FACTORS released by the vascular endothelium and mediates VASODILATION. It also inhibits platelet aggregation, induces disaggregation of aggregated platelets, and inhibits platelet adhesion to the vascular endothelium. Nitric oxide activates cytosolic GUANYLATE CYCLASE and thus elevates intracellular levels of CYCLIC GMP. |
| Arginine | An essential amino acid that is physiologically active in the L-form. |
| trifluoperazine | A phenothiazine with actions similar to CHLORPROMAZINE. It is used as an antipsychotic and an antiemetic. |
| adenosine monophosphate | Adenine nucleotide containing one phosphate group esterified to the sugar moiety in the 2'-, 3'-, or 5'-position. |
| tetradecanoylphorbol acetate | A phorbol ester found in CROTON OIL with very effective tumor promoting activity. It stimulates the synthesis of both DNA and RNA. |
| inositol 1,4,5-trisphosphate | Intracellular messenger formed by the action of phospholipase C on phosphatidylinositol 4,5-bisphosphate, which is one of the phospholipids that make up the cell membrane. Inositol 1,4,5-trisphosphate is released into the cytoplasm where it releases calcium ions from internal stores within the cell's endoplasmic reticulum. These calcium ions stimulate the activity of B kinase or calmodulin. |
| phenolsulfonphthalein | Red dye, pH indicator, and diagnostic aid for determination of renal function. It is used also for studies of the gastrointestinal and other systems. |
| Sodium | A member of the alkali group of metals. It has the atomic symbol Na, atomic number 11, and atomic weight 23. |
| Calcium | A basic element found in nearly all tissues. It is a member of the alkaline earth family of metals with the atomic symbol Ca, atomic number 20, and atomic weight 40. Calcium is the most abundant mineral in the body and combines with phosphorus to form calcium phosphate in the bones and teeth. It is essential for the normal functioning of nerves and muscles and plays a role in blood coagulation (as factor IV) and in many enzymatic processes. |
| aldosterone | A hormone secreted by the ADRENAL CORTEX that regulates electrolyte and water balance by increasing the renal retention of sodium and the excretion of potassium. |
| methylethyl ketone | solvent; colorless synthetic resins, smokeless powders; may be irritating to eyes, mucous membranes; may be toxic in high concentrations; structure |
| Cyclic AMP | An adenine nucleotide containing one phosphate group which is esterified to both the 3'- and 5'-positions of the sugar moiety. It is a second messenger and a key intracellular regulator, functioning as a mediator of activity for a number of hormones, including epinephrine, glucagon, and ACTH. |