Fragile X Syndrome

A condition characterized genotypically by mutation of the distal end of the long arm of the X chromosome (at gene loci FRAXA or FRAXE) and phenotypically by cognitive impairment, hyperactivity, SEIZURES, language delay, and enlargement of the ears, head, and testes. INTELLECTUAL DISABILITY occurs in nearly all males and roughly 50% of females with the full mutation of FRAXA. (From Menkes, Textbook of Child Neurology, 5th ed, p226)

Synonym
Fragile X Syndrome

Excerpt	Reference
"Fragile X syndrome is the most frequent form of inherited mental retardation and segregates as an X-linked dominant with reduced penetrance."	( Caskey, CT; Nelson, DL; Pieretti, M; Saxe, D; Sutcliffe, JS; Warren, ST; Zhang, F, 1992)
"The fragile X syndrome is one of the most common familial causes of mental retardation."	( Davies, KE; Hirst, MC; Kennerknecht, I; Steinbach, P; Wöhrle, D, 1992)
"The fragile X syndrome is a common cause of mental retardation and is associated with a fragile site at Xq27."	( Bell, MV; Christadoulou, Z; Flynn, G; Francis, M; Hirst, MC; Littler, AJ; MacKinnon, RN; Nakahori, Y; Rack, K; Roche, A, 1991)
"Fragile X syndrome is the most common form of inherited mental retardation and results from the transcriptional inactivation of the FMR1 gene."	( Gunter, K; Magenis, RE; Peterson, KL; Popovich, BW; Quan, F; Zonana, J, 1995)
"Fragile X syndrome is characterized as an inherited unstable DNA sequence: the increasement of (CGG)n copy number."	( Fan, Y; Fu, SD; Shen, Y, 1994)
"1."	( Laxova, R, 1994)
"Fragile X syndrome is the most common familial form of mental retardation and known to be associated with the fragile site at Xq27."	( Hori, T; Ishikiriyama, S; Seki, N; Yamauchi, M, 1994)
"Fragile X syndrome is the most common form of inherited mental retardation."	( Wiebe, A; Wiebe, E, 1994)
"Fragile X syndrome is the most common form of inherited mental retardation in man."	( Hornstra, IK; Nelson, DL; Warren, ST; Yang, TP, 1993)
"Fragile X syndrome is caused by a mutation involving expansion of a CGG trinucleotide repeat segment in the fragile X mental retardation-1 (FMR1) gene on the long arm of the X chromosome."	( Carpenter, I; Fall, MZ; Hagerman, RJ; Hull, CE; Lang, KA; Quince, C; Safanda, JF; Staley, LW; Taylor, AK, 1994)
"Fragile X syndrome is a common cause of mental retardation that is inherited as an X-linked dominant disorder with reduced penetrance."	( Nelson, DL; Warren, ST, 1994)
"The fragile X syndrome is commonly associated with mutant alleles of the FMR1 gene that are hypermethylated and have large expansions of CGG repeats."	( Canfield, TK; Gartler, SM; Hansen, RS; Laird, CD; Lamb, MM, 1993)
"Fragile X syndrome is characterized at the molecular level by amplification of a (CGG)n repeat and hypermethylation of a CpG island preceeding the open reading frame of the fragile X gene (FMR-1) located in Xq27."	( Darby, JK; De Boulle, K; de Graaff, E; Jorens, HZ; Oostra, B; Reyniers, E; Van Roy, B; Van Velzen, D; Verkerk, AJ; Vits, L, 1993)
"Fragile X syndrome is the most common form of inherited mental retardation, due to an expansion of the (CGG)n trinucleotide repeat in the FMR-1 gene and hypermethylation of its 5' upstream CpG island."	( Carrió, A; Castellví-Bel, S; Estivill, X; Jiménez, MD; Milà, M; Sánchez, A; Soler, A; Villa, M, 1995)
"Fragile X syndrome is the major cause of inherited mental retardation."	( Carrasco, M; de Diego, Y; Hmadcha, A; Lucas, M; Pintado, E; Sierra, J, 1995)
"The Fragile X syndrome is one of the most frequent forms of mental retardation."	( Bañares, VG, 1995)
"Fragile X syndrome is the most common cause of inherited mental retardation."	( Badenas, C; Castellví-Bel, S; Estivill, X; Giné, R; Milà, M; Sánchez, A; Vazquez, C, 1996)
"Fragile X syndrome is associated with silencing of the FMR1 gene."	( de Graaff, E; Deissler, H; Döerfler, W; Dörfler, W; Gläser, D; Just, W; Kennerknecht, I; Oostra, BA; Schwemmle, S; Steinbach, P; Vogel, W; Wöhrle, D, 1997)
"Fragile X syndrome is the most frequent form of inherited mental retardation and it is caused by deficiency of FMRP, the protein encoded by the FMR1 gene."	( Bardoni, B; Mandel, JL; Shen, Y; Sittler, A, 1997)
"Fragile X syndrome is caused by the absence of the fragile X mental retardation protein (FMRP)."	( Anar, B; Bakker, CE; Bontekoe, C; Galjaard, H; Hoogeveen, AT; Oostra, BA; Tamanini, F; van Unen, L; Willemsen, R; Yoshida, M, 1999)
"Fragile X syndrome is associated with the expansion of the number of CGG trinucleotide tandem repeats at the 5' untranslated region of the FMR1 gene."	( Aman, P; Kristoffersson, U; Lassen, C; Panagopoulos, I, 1999)
"Fragile X syndrome is caused by the absence of the fragile X mental-retardation protein (FMRP)."	( Bakker, C; Bontekoe, C; Galjaard, H; Hoogeveen, AT; Kirkpatrick, LL; Nelson, DL; Oostra, BA; Schonkeren, J; Tamanini, F; van Unen, L, 2000)
"Fragile X syndrome is a common cause of mental retardation that results from the absence of the fragile X mental retardation protein (FMRP), an RNA binding protein whose function remains unclear."	( Mack, KJ; Todd, PK, 2000)
"Fragile X syndrome is a common form of inherited mental retardation."	( Fischer, U; Keidel, EM; Laggerbauer, B; Ostareck, D; Ostareck-Lederer, A, 2001)
"Fragile X syndrome is a neurodevelopmental disorder that results from a single gene mutation on the X chromosome."	( Scully, C, 2002)
"Fragile X syndrome is caused by an expansion of a polymorphic CGG triplet repeat that results in silencing of FMR1 expression."	( Ceman, S; Coffee, B; Reines, D; Warren, ST; Zhang, F, 2002)
"Fragile X syndrome is caused by loss of FMR1 protein expression."	( Higashijima, K; Ishizuka, A; Siomi, H; Siomi, MC, 2002)
"Fragile X syndrome is an inherited cause of mental retardation."	( Avoli, M; D'Antuono, M; Merlo, D, 2003)
"Fragile X syndrome is caused by a loss of expression of the fragile X mental retardation protein (FMRP)."	( Ceman, S; Jin, P; Jongens, TA; Moses, K; Mowrey, J; Nakamoto, M; Nelson, DL; Warren, ST; Zarnescu, DC, 2004)
"Fragile X syndrome is caused by the absence of the mRNA-binding protein Fragile X mental retardation protein (FMRP), which may play a role in activity-regulated localization and translation of mRNA in dendrites and at synapses."	( Afroz, R; Antar, LN; Bassell, GJ; Carroll, RC; Dictenberg, JB, 2004)
"Fragile X syndrome is an X-linked form of mental retardation including, among others, symptoms such as stereotypic behaviour, hyperactivity, hyperarousal, and cognitive deficits."	( Catania, MV; Musumeci, SA; Pascucci, T; Puglisi-Allegra, S; Ventura, R, 2004)
"Fragile X syndrome is the most common form of inherited mental retardation, associated with both cognitive and behavioral anomalies."	( Broadie, K; Friedman, DB; O'donnell, J; Pan, L; Wang, Z; Woodruff, E; Zhang, YQ, 2005)
"The fragile X syndrome is caused by a >200 CGG repeat expansion within the FMR1 gene promoter, with consequent DNA hypermethylation and inactivation of its expression."	( Chiurazzi, P; Moscato, U; Neri, G; Oostra, BA; Pietrobono, R; Tabolacci, E, 2005)
"Fragile X syndrome is a leading heritable cause of mental retardation that results from the loss of FMR1 gene function."	( Braunstein, E; Choi, CH; Dockendorff, TC; Ferreiro, D; Jongens, TA; Liebelt, D; McBride, SM; McDonald, TV; Nguyen, HT; Sehgal, A; Siwicki, KK; Wang, Y, 2005)
"Fragile X Syndrome is the most common form of inherited mental retardation worldwide."	( Bauchwitz, RP; Rammal, M; Tranfaglia, M; Yan, QJ, 2005)
"Fragile X Syndrome is a leading heritable cause of mental retardation that results from the loss of FMR1 gene function."	( Lardelli, M; Richards, RI; Tucker, B, 2006)
"Fragile X Syndrome is the most common form of hereditary mental retardation."	( Botas, J; Jin, P; Nelson, DL; Sofola, OA, 2007)
"Fragile X syndrome is the most common form of inherited mental retardation in humans."	( de Diego-Otero, Y; Decara, J; Del Arco-Herrera, I; el Bekay, R; Rodríguez-de Fonseca, F; Romero-Zerbo, Y; Sanchez-Salido, L, 2007)
"Fragile X syndrome is caused by the functional loss of the fragile X mental retardation 1 (FMR1) gene."	( Bray, SM; Chang, S; He, C; Jin, P; Li, Z; Warren, ST; Zarnescu, DC, 2008)
"Fragile X syndrome is associated with expansion of a CGG triplet repeat in the FMR1 gene, which abolishes production of the FMRP protein."	( Bricout, VA; Eberhard, Y; Faure, P; Favre-Juvin, A; Flore, P; Guinot, M, 2008)
"Fragile X syndrome is the most common genetic cause of mental disability."	( de Diego-Otero, Y; Decara, J; del Arco-Herrera, I; el Bekay, R; Rodriguez-de Fonseca, F; Romero-Zerbo, Y; Sanchez, L, 2009)
"Fragile X syndrome is the most common form of inherited mental retardation."	( de Diego-Otero, Y; de Fonseca, FR; Decara, J; Del Arco-Herrera, I; el Bekay, R; Romero-Zerbo, Y; Sanchez-Salido, L, 2009)
"Fragile X syndrome is the most common inherited cause of developmental disability and the most common known single gene cause of ASDs."	( Erickson, CA; McDougle, CJ; Posey, DJ; Stigler, KA, 2010)
"Fragile X Syndrome is the most common known genetic cause of autism."	( El Idrissi, A; L'Amoreaux, W; Neuwirth, LS, 2010)
"Fragile X syndrome is an X-linked mental retardation with abnormal dendritic protrusions from neurons in the brain."	( de Jong, R; Mansvelder, HD; Meredith, RM, 2011)
"Fragile X syndrome is one of the X-linked disorders associated with moderate to severe mental retardation."	( Guruju, MR; Katikala, L; Madireddi, S; Persha, A; Spurgeon, AM; Vallamkonda, N; Vallamkonda, O, 2011)
"Fragile X syndrome is the most common type of inherited mental retardation caused by the absence of FMRP protein, a RNA-binding protein implicated in the regulation of mRNA translation and transport, leading to protein synthesis."	( Bongmba, OY; Butler, K; Elhardt, ME; Martinez, LA; Tejada-Simon, MV, 2011)
"Fragile X syndrome is the most frequent hereditary cause of mental retardation after Down syndrome."	( Arabandi, R; Chong, SS; Indhumathi, N; Singh, D; Srisailpathy, CR; Thelma, BK, 2012)
"Fragile X syndrome is a common inherited form of mental retardation caused by the lack of fragile X mental retardation protein (FMRP) because of Fmr1 gene silencing."	( Chen, GS; Li, XQ; Liu, G; Liu, SB; Ma, L; Wu, YM; Xu, ZH; Yang, Q; Zhao, MG, 2012)
"Fragile X syndrome is caused by lack of FMR1 protein (FMRP) leading to severe symptoms, including intellectual disability, hyperactivity and autistic-like behaviour."	( Buijsen, RA; D'Hooge, R; de Esch, CE; Gantois, I; Gasparini, F; Gomez-Mancilla, B; Oostra, BA; Pooters, T; Pop, AS; Willemsen, R, 2013)
"The fragile X syndrome is a mutation-driven developmental disorder caused by a repetition over 200 times of the CGG trinucleotide situated in the 5'-untranslated region of the fragile X mental retardation 1 gene (FMR1)."	( Carrillo, F; Conde, V; Lama, MJ; Martínez, R; Mir, P; Palomar, FJ; Pintado, E, 2013)
"Fragile X syndrome is the most common monogenetic form of intellectual disability and autism."	( Buijsen, RA; de Esch, CE; Gasparini, F; Jaafar, IA; Kushner, SA; Nieuwenhuizen-Bakker, IM; van den Berg, WE; Willemsen, R, 2015)
"Fragile X syndrome is a learning disability caused by excess of CGG repeats in the 5' untranslated region of the Fragile X gene (FMR1) silencing its transcription and translation."	( Djazayeri, S; Liu, YY; Norman, KM; Roch, M; Scremin, OU, 2015)
"Fragile X syndrome is the most common genetic cause of mental disability."	( Calvo-Medina, R; de Diego-Otero, Y; el Bekay, R; Garcia-Guirado, F; Lima-Cabello, E; Perez-Costillas, L; Quintero-Navarro, C; Sanchez-Salido, L, 2016)
"Fragile X syndrome is the most common cause of inherited intellectual disability in humans."	( Dolskiy, AA; Lemskaya, NA; Pustylnyak, VO; Yarushkin, AA; Yudkin, DV, 2017)
"Fragile X Syndrome is a neurodevelopmental disorder which affects intellectual, social and physical development due to mutation of the Fragile X mental retardation 1 (FMR1) gene."	( Bonn-Miller, M; Gutterman, D; Karl, T; Sebree, T; Siegel, S; Sinclair, D; Zieba, J, 2019)
"Fragile X syndrome is an X-linked dominant disorder and the most common cause of inherited mental retardation."	( El Idrissi, A; Lin, S, 2019)
"Fragile X syndrome is one of the most common monogenic causes of ASD, characterized by a mutation in the X chromosome which alters the expression of the fragile X mental retardation protein (FMRP)."	( Cabré, M; Colomina, MT; Giménez, E; Guardia-Escote, L; Matamala Montoya, M; Morales-Navas, M; Perez-Fernandez, C; Sánchez-Santed, F, 2022)

Excerpt	Reference
"Fragile X syndrome has been shown to be caused by an unstable CGG repeat within the fragile X mental retardation-1 (FMR1) gene."	( Nelson, DL; Warren, ST, 1994)

Excerpt	Reference
"Fragile X syndrome affected families were studied cytogenetically and by the use of DNA probes flanking the fragile X region: 1A1, U6."	( Antich, J; Carballo, M; Espinás, ML; Giné, R, 1992)

Excerpt	Reference
"To date, no drug is approved for the treatment of Fragile X Syndrome (FXS) although many drugs are used to manage challenging behaviors from a symptomatic perspective in this population."	( Davenport, MH; Erickson, CA; Fitzpatrick, SE; Friedmann, KJ; Schaefer, TL, 2016)
"The histories of targeted treatment trials in fragile X syndrome (FXS) are reviewed in animal studies and human trials."	( Clark, C; Hagerman, R; Johnson, D, 2023)

Timeframe	Studies, This Condition (%)	All Conditions %
pre-1990	71 (8.74)	23.3326
1990's	188 (23.15)	12.5806
2000's	151 (18.60)	18.1394
2010's	307 (37.81)	28.8240
2020's	95 (11.70)	9.53

Drug	Relationship Strength	Studies	Trials
acetylcarnitine	medium	9	3
phosphoserine	low	1	0
gamma-aminobutyric acid	medium	30	1
acetone	low	1	0
adenine	low	1	0
agmatine	low	1	0
betaine	low	3	0
butyric acid	low	1	0
carbamates	low	1	0
carnitine	low	1	0
choline	medium	3	1
salicylic acid	low	4	0
3,4-dihydroxyphenylacetic acid	low	1	0
creatine	medium	2	1
cytosine	low	17	0
lactic acid	low	1	0
dimethyl sulfoxide	low	1	0
glycine	low	10	0
methanol	low	1	0
melatonin	medium	6	1
niacinamide	low	1	0
nitrates	low	1	0
nitrites	low	1	0
pyruvic acid	low	1	0
sulfites	low	7	0
taurine	medium	11	1
thymine	low	1	0
toluene	low	1	0
urea	low	1	0
2-amino-5-phosphonovalerate	low	2	0
8-hydroxy-2-(di-n-propylamino)tetralin	low	1	0
alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid	low	1	0
3-methoxytyramine	low	1	0
homovanillic acid	low	1	0
phenytoin	low	1	0
5-carboxamidotryptamine	low	1	0
hydroxyindoleacetic acid	low	1	0
am 251	low	1	0
amitriptyline	low	1	0
aspirin	low	1	0
bumetanide	low	1	0
caffeine	low	3	0
carbamazepine	low	1	0
chloral hydrate	low	1	0
chloroxylenol	low	1	0
chlorpyrifos	low	1	0
chlorzoxazone	low	1	0
citalopram	low	1	0
clomiphene	low	1	0
clonazepam	low	1	0
clonidine	low	5	0
2,3-dimethoxy-5-methyl-6-decyl-1,4-benzoquinone	low	1	0
amphetamine	low	2	0
diazepam	low	3	0
dicyclomine	low	1	0
diethyl pyrocarbonate	low	1	0
dipyridamole	low	1	0
stallimycin	low	1	0
disulfiram	low	1	0
valproic acid	medium	5	1
erythrosine	low	1	0
ethidium	low	5	0
hydroxyurea	low	2	0
imipramine	low	1	0
1-methyl-3-isobutylxanthine	low	1	0
2-propanol	low	1	0
ketanserin	low	1	0
kojic acid	low	1	0
2-amino-3-phosphonopropionic acid	low	1	0
pyrrolidine-2,4-dicarboxylic acid	low	1	0
losartan	low	1	0
mechlorethamine	low	1	0
methadone	low	1	0
nocodazole	low	1	0
methyl methanesulfonate	low	1	0
methylphenidate	low	4	0
metoprolol	low	1	0
apnea	low	1	0
nan 190	low	1	0
nipecotic acid	low	1	0
pifithrin	low	1	0
pirenperone	low	2	0
potassium chloride	low	2	0
propidium	low	1	0
propofol	medium	2	1
propranolol	medium	1	1
pyrimethamine	low	1	0
riluzole	medium	1	1
risperidone	low	3	0
rolipram	low	1	0
fenofibrate	low	2	0
vorinostat	low	2	0
sulforaphane	low	1	0
tetraethylammonium	low	1	0
trifluoperazine	low	1	0
trihexyphenidyl	low	1	0
trimethoprim	low	3	0
tropicamide	low	1	0
corticosterone	low	5	0
reserpine	low	1	0
thymidine	low	15	0
floxuridine	low	21	0
thyroxine	low	1	0
dextroamphetamine	low	1	0
carbachol	low	1	0
penicillamine	low	1	0
dehydroepiandrosterone	low	1	0
alanine	low	2	0
serine	low	8	0
aspartic acid	low	3	0
glutamine	low	2	0
lysine	low	3	0
tetrabenazine	low	1	0
uridine	low	2	0
bromodeoxyuridine	low	12	0
carbostyril	medium	4	1
levodopa	low	1	0
tyrosine	low	3	0
leucine	low	5	0
uridine triphosphate	low	1	0
methionine	low	6	0
cycloheximide	low	1	0
trifluridine	low	1	0
ornithine	medium	1	1
asparagine	low	3	0
histidine	low	2	0
valine	low	3	0
isoleucine	low	3	0
arginine	low	4	0
phencyclidine	low	1	0
dimethyl sulfate	low	2	0
bisphenol a	low	1	0
quinoxalines	low	2	0
cyclohexanol	low	2	0
catechin	medium	2	1
quinazolines	low	2	0
cyclopentane	low	1	0
isoxazoles	low	4	0
thiazoles	low	2	0
azacitidine	low	12	0
thymidine monophosphate	low	5	0
2-aminopurine	low	1	0
hydantoins	low	1	0
propadiene	low	1	0
limestone	low	1	0
kainic acid	low	3	0
psilocybin	low	2	0
methoxyhydroxyphenylglycol	low	15	0
methamphetamine	low	1	0
aminoacetonitrile	low	1	0
lithium carbonate	medium	3	1
acetylcysteine	low	2	0
deoxycytidine	low	3	0
deoxyuridine	low	1	0
cytidine diphosphate choline	medium	1	1
d-alpha tocopherol	medium	3	1
digoxigenin	low	1	0
paraquat	low	1	0
s,n,n'-tripropylthiocarbamate	low	4	0
n-methylaspartate	low	3	0
technetium	low	2	0
gold	low	3	0
acetylglucosamine	low	1	0
metoprine	low	1	0
deuterium	low	1	0
1,6-hexanediol diacrylate	low	1	0
phosphotyrosine	low	1	0
carbamide peroxide	low	1	0
pregnanolone	medium	8	2
transferrin	low	2	0
glutamic acid	low	21	0
azides	low	1	0
etoposide	low	1	0
colforsin	low	2	0
fenoxycarb	low	1	0
adenosine	low	5	0
venlafaxine hydrochloride	low	2	0
thymidine 5'-triphosphate	low	2	0
5-methylcytosine	low	5	0
2'-deoxyuridylic acid	low	1	0
n-acetylaspartic acid	low	1	0
2'-deoxycytidine 5'-triphosphate	low	1	0
dopamine hydrochloride	low	1	0
methacycline	low	2	0
triazoles	low	2	0
fluorodeoxyglucose f18	low	2	0
5-hydroxymethylcytosine	low	1	0
uk 68798	low	1	0
7-hydroxystaurosporine	low	1	0
methotrimeprazine	low	1	0
6-carboxyfluorescein	low	1	0
d-aspartic acid	low	1	0
bromates	low	1	0
3,4-dihydroxyphenylglycol	low	14	0
homocysteine	low	3	0
aluminum maltolate	low	1	0
pyrimidine dimers	low	1	0
n-methyladenosine	low	1	0
hydrogen sulfite	low	3	0
alphaxalone	low	1	0
sr141716	low	1	0
dihydrokainate	low	1	0
sr 95531	low	1	0
3,5-dihydroxyphenylglycine	low	1	0
n-acetylglucosaminylasparagine	low	1	0
methotrexate	low	6	0
cercosporamide	low	1	0
omega-n-methylarginine	low	1	0
bdp 12	medium	2	1
peptide elongation factor 2	low	1	0
varenicline	low	1	0
biotin	low	2	0
atropine	low	1	0
sb 216763	low	1	0
n(delta)-acetylornithine	medium	1	1
cgp 54626	low	1	0
lurasidone	low	1	0
bms204352	low	1	0
3-nitrotyrosine	low	1	0
anisomycin	low	1	0
benzofurans	low	2	0
bortezomib	low	2	0
4-aminopiperidine	low	1	0
carboplatin	low	1	0
lithium chloride	low	3	0
leptomycin b	low	1	0
s-adenosylhomocysteine	low	1	0
elastin	low	2	0
formiminoglutamic acid	low	1	0
inositol 3-phosphate	low	2	0
phalloidine	low	1	0
ergonovine	low	1	0
trichostatin a	low	6	0
tretinoin	low	1	0
arachidonic acid	low	1	0
1,5-dihydro-fad	low	1	0
cocaine	low	2	0
eicosapentaenoic acid	low	1	0
afimoxifene	low	1	0
decitabine	low	10	0
dactinomycin	low	1	0
aphidicolin	low	5	0
5-fluoro-2'-deoxycytidine	low	2	0
alpha-asarone	low	1	0
isomethyleugenol	medium	96	1
flavin-adenine dinucleotide	low	1	0
pilocarpine nitrate	low	1	0
n(6)-cyclopentyladenosine	low	1	0
dienestrol	low	1	0
cotinine	low	1	0
vu 0155041	low	1	0
urb 597	low	1	0
phenacylamine monohydrochloride	low	1	0
3-hydroxybenzylhydrazine hydrochloride	low	1	0
tamoxifen	low	2	0
nadp	low	1	0
u 0126	low	1	0
6-methyl-2-(phenylethynyl)pyridine	low	17	0
lithium	low	4	0
u 71184	low	1	0
ee 581	low	1	0
pc 12 ester	low	1	0
freedom	low	1	0
fg 9041	low	1	0
myelin basic protein	low	1	0
ku 55933	low	1	0
linoleic acid	low	1	0
11-cis-retinal	low	1	0
alprostadil	low	1	0
anandamide	low	2	0
glyceryl 2-arachidonate	low	2	0
isotretinoin	low	1	0
sirolimus	low	5	0
topiramate	low	1	0
dexmedetomidine	low	1	0
mdl 100907	low	1	0
casein kinase ii	low	1	0
6,7-dihydroxyflavone	low	2	0
aluminum	low	1	0
cysteine	low	1	0
phosphorus	low	1	0
tetrodotoxin	low	3	0
dizocilpine maleate	low	1	0
ergonovine maleate	low	1	0
fm1 43	low	1	0
s-nitroso-n-acetylpenicillamine	low	1	0
n,n'-dicyclopentyl-2-methylsulfanyl-5-nitro-pyrimidine-4,6-diamine	low	1	0
staurosporine	low	2	0
sl 327	low	1	0
paliperidone palmitate	low	1	0
flag peptide	low	1	0
tgx 221	low	1	0
cc 1065	low	1	0
cp 31398	low	1	0
cgp 55845a	low	1	0
adociasulfate-2	low	1	0
2-carbomethoxy-8-(3-fluoropropyl)-3-(4-iodophenyl)tropane	low	4	0
alpha-synuclein	low	1	0
ribose	low	1	0
3-cyano-n-(1,3-diphenyl-1h-pyrazol-5-yl)benzamide	low	1	0
arbaclofen placarbil	low	2	0
nutlin-3a	low	2	0
apremilast	low	1	0
cannabidivarin	low	1	0
ro 4956371	low	4	0
scopolamine hydrobromide	low	1	0
pituitrin	low	1	0
enerbol	low	1	0
glucagon	low	2	0
oligonucleotides	low	18	0
atractyloside	low	1	0
nsc 23766	low	2	0
ubiquinone	low	3	0
sodium bisulfite	low	3	0
potassium bromate	low	1	0
cx 4945	low	1	0
s-adenosylmethionine	low	1	0
picrotoxin	low	1	0
neurotensin	low	1	0
piperidines	medium	11	3
bryostatin 1	low	3	0
7,8-dihydroxyflavanone	low	1	0
interleukin-8	low	1	0
unc 0638	low	1	0
tak-063	low	1	0
bix 01294	low	1	0
pf-4708671	low	2	0
vasoactive intestinal peptide	low	1	0
heme	low	1	0
ascorbic acid	medium	1	1
minocycline	medium	15	4
transforming growth factor beta	low	1	0
frax486	low	1	0
8-(trifluoromethyl)-1,2,3,4,5-benzopentathiepin-6-amine	low	1	0
caseins	low	1	0
carboxyatractyloside	low	1	0
vitamin b 12	low	3	0
cyclosporine	low	1	0
cytochalasin d	low	1	0
exudates	low	1	0
tautomycin	low	1	0
levoleucovorin	medium	1	1
cyclic gmp	low	1	0
deoxyguanosine	low	2	0
guanosine diphosphate	low	2	0
guanosine triphosphate	low	1	0
guanine	low	13	0
guanosine	low	2	0
folic acid	medium	60	4
7-deazaguanine	low	1	0
5,6,7,8-tetrahydrofolic acid	low	1	0
8-hydroxy-2'-deoxyguanosine	low	1	0
cytidylyl-3'-5'-guanosine	medium	27	1
fenobam	medium	5	1
eye	low	10	0
carbidopa	low	1	0
phosphorus radioisotopes	low	1	0
leptin	low	4	0
pyrimidinones	low	1	0

Protein Targets (2,359)

Protein	Potency Measurements	Inhibition Measurements	Activation Measurements	Drugs
Chain A, High-affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A	0	1	0	1
Chain A, cAMP-specific 3',5'-cyclic phosphodiesterase 4D	0	1	0	1
Chain A, Phosphodiesterase 9A	0	1	0	1
Chain A, JmjC domain-containing histone demethylation protein 3A	20	0	0	20
Chain A, Class I phosphodiesterase PDEB1	0	1	0	1
Chain A, High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A	0	1	0	1
Chain A, cGMP-dependent 3',5'-cyclic phosphodiesterase	0	1	0	1
Chain A, cGMP-specific 3',5'-cyclic phosphodiesterase catalytic domain, Cone cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha chimera	0	1	0	1
Chain A, cGMP-specific 3',5'-cyclic phosphodiesterase catalytic domain, Cone cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha chimera	0	1	0	1
Chain A, High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A	0	1	0	1
Chain A, High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A	0	1	0	1
glp-1 receptor, partial	23	0	0	23
thyroid stimulating hormone receptor	41	0	0	41
estrogen-related nuclear receptor alpha	83	0	0	83
Phosphodiesterase	0	2	0	2
mitogen-activated protein kinase 1	18	0	0	18
geminin	72	0	0	72
cytochrome P450 3A4 isoform 1	49	0	0	49
histone acetyltransferase KAT2A isoform 1	35	0	0	35
cGMP-dependent 3',5'-cyclic phosphodiesterase	0	5	0	5
Gamma-aminobutyric acid receptor subunit pi	49	18	4	71
Monocarboxylate transporter 4	0	1	0	2
High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A	0	3	0	3
cGMP-specific 3',5'-cyclic phosphodiesterase	0	6	0	7
High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A	0	2	0	2
Renin	0	3	0	3
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A	0	2	0	2
cAMP-specific 3',5'-cyclic phosphodiesterase 4D	0	3	0	4
cAMP-specific 3',5'-cyclic phosphodiesterase 4C	0	3	0	4
cAMP-specific 3',5'-cyclic phosphodiesterase 4B	0	3	0	5
Gamma-aminobutyric acid receptor subunit beta-1	49	18	4	71
Gamma-aminobutyric acid receptor subunit delta	49	18	4	71
Gamma-aminobutyric acid receptor subunit gamma-2	49	18	6	73
Gamma-aminobutyric acid receptor subunit alpha-5	49	18	4	71
Gamma-aminobutyric acid receptor subunit alpha-3	49	18	4	71
Gamma-aminobutyric acid receptor subunit gamma-1	49	19	4	72
Gamma-aminobutyric acid receptor subunit alpha-2	49	18	4	71
Adenosine receptor A1	1	11	2	20
Gamma-aminobutyric acid receptor subunit alpha-4	49	18	4	71
Gamma-aminobutyric acid receptor subunit gamma-3	49	18	4	71
Adenosine receptor A3	0	5	0	5
Adenosine receptor A2a	0	10	5	19
Adenosine receptor A2b	0	2	2	8
Adenosine receptor A2b	0	8	2	13
Gamma-aminobutyric acid receptor subunit alpha-6	49	18	4	71
Adenosine receptor A1	0	13	5	24
Adenosine receptor A2a	0	11	2	20
Sodium-dependent serotonin transporter	0	11	1	13
Adenosine receptor A2a	0	2	0	2
Cone cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha'	0	2	0	2
cAMP-specific 3',5'-cyclic phosphodiesterase 4A	0	3	0	4
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A	0	4	0	5
Gamma-aminobutyric acid receptor subunit alpha-1	49	19	6	74
Gamma-aminobutyric acid receptor subunit beta-3	49	18	4	71
Gamma-aminobutyric acid receptor subunit beta-2	49	18	6	73
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B	0	2	0	2
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B	0	4	0	5
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B	0	3	0	3
cAMP-specific 3',5'-cyclic phosphodiesterase 4B	0	8	1	9
cAMP-specific 3',5'-cyclic phosphodiesterase 4D	0	9	1	11
cGMP-inhibited 3',5'-cyclic phosphodiesterase B	0	7	0	8
Voltage-dependent L-type calcium channel subunit alpha-1C	0	11	0	11
High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A	0	4	0	4
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C	0	4	0	5
cGMP-inhibited 3',5'-cyclic phosphodiesterase A	0	7	0	8
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C	0	3	0	3
Phosphodiesterase	0	1	0	1
GABA theta subunit	49	18	4	71
Phosphodiesterase	0	3	0	3
Gamma-aminobutyric acid receptor subunit epsilon	49	18	4	71
cAMP-specific 3',5'-cyclic phosphodiesterase 7B	0	3	0	3
interleukin 8	10	0	0	10
hypoxia-inducible factor 1 alpha subunit	25	0	0	25
RAR-related orphan receptor gamma	61	0	0	61
SMAD family member 2	21	0	0	21
SMAD family member 3	21	0	0	21
GLI family zinc finger 3	65	0	0	65
AR protein	88	0	0	88
aldehyde dehydrogenase 1 family, member A1	54	0	0	54
estrogen receptor 2 (ER beta)	38	0	0	38
nuclear receptor subfamily 1, group I, member 3	55	0	0	55
progesterone receptor	37	0	0	37
glucocorticoid receptor [Homo sapiens]	60	0	0	60
retinoic acid nuclear receptor alpha variant 1	61	0	0	61
retinoid X nuclear receptor alpha	53	0	0	53
farnesoid X nuclear receptor	39	0	0	39
pregnane X nuclear receptor	52	0	0	52
estrogen nuclear receptor alpha	97	0	0	97
peroxisome proliferator-activated receptor delta	35	0	0	35
peroxisome proliferator activated receptor gamma	42	0	0	42
vitamin D (1,25- dihydroxyvitamin D3) receptor	38	0	0	38
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a	47	0	0	47
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a	25	0	0	25
v-jun sarcoma virus 17 oncogene homolog (avian)	35	0	0	35
Histone H2A.x	32	0	0	32
Caspase-7	12	0	0	12
thyroid hormone receptor beta isoform a	26	0	0	26
caspase-3	12	0	0	12
thyroid hormone receptor beta isoform 2	62	0	0	62
heat shock protein beta-1	27	0	0	27
nuclear factor NF-kappa-B p105 subunit isoform 1	5	0	0	5
nuclear factor erythroid 2-related factor 2 isoform 1	60	0	0	60
nuclear receptor ROR-gamma isoform 1	32	0	0	32
Voltage-dependent calcium channel gamma-2 subunit	42	0	0	42
Cellular tumor antigen p53	56	2	0	58
Glutamate receptor 2	43	8	4	56
Nuclear receptor ROR-gamma	14	1	1	16
ATPase family AAA domain-containing protein 5	25	0	0	25
Ataxin-2	36	0	0	36
Chain A, Retinaldehyde-binding protein 1	0	0	1	1
Chain A, Retinaldehyde-binding protein 1	0	0	1	1
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE	58	0	0	58
phosphopantetheinyl transferase	44	0	0	44
arylsulfatase A	39	0	0	39
euchromatic histone-lysine N-methyltransferase 2	99	0	0	99
Bloom syndrome protein isoform 1	45	0	0	45
peripheral myelin protein 22 isoform 1	22	0	0	22
flap endonuclease 1	24	0	0	24
lamin isoform A-delta10	60	0	0	60
N(4)-(beta-N-acetylglucosaminyl)-L-asparaginase	0	2	0	2
Inositol monophosphatase 1	15	0	0	15
D(1A) dopamine receptor	25	0	0	25
Glutamate receptor 1	1	9	4	15
Glutamate receptor ionotropic, NMDA 1	0	24	4	34
Glutamate receptor ionotropic, kainate 3	0	8	0	9
Glutamate receptor ionotropic, NMDA 2A	0	23	4	33
Glutamate receptor ionotropic, NMDA 2B	0	25	4	35
Glutamate receptor ionotropic, NMDA 2C	0	23	4	34
Glutamate receptor ionotropic, NMDA 2D	0	23	4	33
Glutamate receptor ionotropic, NMDA 3B	0	23	4	33
Glutamate receptor ionotropic, NMDA 3A	0	23	4	33
ATP-dependent phosphofructokinase	37	0	0	37
Chain A, Beta-lactamase	21	0	0	21
thioredoxin reductase	57	0	0	57
IDH1	36	0	0	36
Phosphatidylinositol 4-kinase alpha	0	4	0	5
Xanthine dehydrogenase/oxidase	0	3	0	3
Guanine nucleotide-binding protein G	7	0	0	7
TAR DNA-binding protein 43	14	0	0	14
Phosphatidylinositol 4-kinase type 2-beta	0	4	0	5
Phosphatidylinositol 4-kinase type 2-alpha	0	4	0	5
Phosphatidylinositol 4-kinase beta	0	4	0	5
Sodium-dependent dopamine transporter	0	25	2	27
Luciferase	23	0	0	23
aryl hydrocarbon receptor	24	0	0	24
DNA repair and recombination protein RadA	0	0	1	1
Cytochrome P450 1A2	0	10	1	12
Cytochrome P450 2A6	0	5	0	5
Sulfotransferase 1A1	0	0	0	1
Cytochrome P450 2A5	0	3	0	3
Sulfotransferase 1E1	0	0	0	1
Sulfotransferase 1A1	0	0	0	1
Sulfotransferase 2A1	0	0	0	1
activating transcription factor 6	30	0	0	30
Chain A, TYROSYL-DNA PHOSPHODIESTERASE	28	0	0	28
Chain A, Putative fructose-1,6-bisphosphate aldolase	15	0	0	15
Chain A, Ferritin light chain	31	0	0	31
TDP1 protein	87	0	0	87
Microtubule-associated protein tau	49	0	0	49
regulator of G-protein signaling 4	37	0	0	37
vitamin D3 receptor isoform VDRA	34	0	0	34
Dihydroorotate dehydrogenase (quinone), mitochondrial	0	0	0	1
Dihydroorotate dehydrogenase (quinone), mitochondrial	0	0	0	1
Reverse transcriptase/RNaseH	0	4	3	10
Chain A, Protein (thymidylate Synthase)	0	0	1	1
Chain A, Thymidylate Synthase	0	0	1	1
Chain A, Thymidylate Synthase	0	0	1	1
Chain A, Thymidylate Synthase	0	0	1	1
Chain A, Thymidylate Synthase	0	0	1	1
Chain A, Thymidylate Synthase	0	0	1	1
Chain A, Thymidylate Synthase	0	0	1	1
Chain A, Thymidylate Synthase	0	0	1	1
Chain A, Thymidylate Synthase	0	0	1	1
Chain A, Thymidylate Synthase	0	0	1	1
Chain A, Thymidylate Synthase	0	0	1	1
Thymidylate synthase	0	1	0	2
Thymidylate synthase	0	3	0	4
Thymidylate synthase	0	6	0	7
Thymidylate synthase	0	5	0	7
Thymidylate kinase	0	2	0	4
Gonadotropin-releasing hormone receptor	0	1	0	1
Thymidylate kinase	0	4	0	6
Thymidylate synthase	0	1	0	1
Deoxyuridine triphosphatase, putative	0	1	0	1
cytochrome P450 family 3 subfamily A polypeptide 4	50	0	0	50
G	34	0	0	34
Interferon beta	48	0	0	48
HLA class I histocompatibility antigen, B alpha chain	34	0	0	34
Metabotropic glutamate receptor 5	0	7	2	9
Metabotropic glutamate receptor 5	0	12	4	17
Inositol hexakisphosphate kinase 1	34	0	0	34
cytochrome P450 2C9, partial	34	0	0	34
Chain A, 2-oxoglutarate Oxygenase	30	0	0	30
muscarinic acetylcholine receptor M1	35	0	0	35
D(2) dopamine receptor	0	16	2	18
Trace amine-associated receptor 1	0	0	3	3
bromodomain adjacent to zinc finger domain 2B	17	0	0	17
pyruvate kinase PKM isoform a	2	0	0	2
Glycoprotein hormones alpha chain	3	0	0	3
Tubulin--tyrosine ligase	0	2	0	2
Chain A, Penicillin Amidohydrolase	0	1	0	1
Chain B, Penicillin Amidohydrolase	0	1	0	1
Chain A, Penicillin Amidohydrolase	0	1	0	1
Chain B, Penicillin Amidohydrolase	0	1	0	1
Chain A, Penicillin Amidohydrolase	0	1	0	1
Chain B, Penicillin Amidohydrolase	0	1	0	1
Chain A, Penicillin Amidohydrolase	0	1	0	1
Chain B, Penicillin Amidohydrolase	0	1	0	1
Chain A, Penicillin Amidohydrolase	0	1	0	1
Chain B, Penicillin Amidohydrolase	0	1	0	1
Chain A, Penicillin Amidohydrolase	0	1	0	1
Chain B, Penicillin Amidohydrolase	0	1	0	1
Chain A, Penicillin Amidohydrolase	0	1	0	1
Chain B, Penicillin Amidohydrolase	0	1	0	1
Chain A, HADH2 protein	30	0	0	30
Chain B, HADH2 protein	30	0	0	30
Chain A, Protocatechuate 3,4-dioxygenase	0	0	1	1
Chain M, Protocatechuate 3,4-dioxygenase	0	0	1	1
Olfactory receptor class A-like protein 1	0	0	1	1
endonuclease IV	13	0	0	13
RGS12	3	0	0	3
NFKB1 protein, partial	20	0	0	20
GLS protein	35	0	0	35
Thrombopoietin	16	0	0	16
alkaline phosphatase, intestinal	0	0	1	1
thioredoxin glutathione reductase	9	0	0	9
apical membrane antigen 1, AMA1	9	0	0	9
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)	15	0	0	15
hypothetical protein, conserved	5	0	0	5
lysosomal alpha-glucosidase preproprotein	10	0	0	10
alkaline phosphatase, tissue-nonspecific isozyme isoform 1 preproprotein	0	1	0	1
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 1	23	0	0	23
intestinal alkaline phosphatase precursor	0	1	0	1
chromobox protein homolog 1	52	0	0	52
guanine nucleotide-binding protein G(i) subunit alpha-1 isoform 1	3	0	0	3
DNA polymerase beta	11	0	0	11
DNA polymerase iota isoform a (long)	31	0	0	31
M-phase phosphoprotein 8	15	0	0	15
alkaline phosphatase, germ cell type preproprotein	0	0	1	1
POsterior Segregation	0	0	3	3
Prolyl 4-hydroxylase subunit alpha-1	0	2	0	2
Sodium-dependent noradrenaline transporter	0	30	6	36
Zinc finger protein mex-5	0	0	3	3
Chain A, ATP-DEPENDENT DNA HELICASE Q1	15	0	0	15
Chain A, AROMATIC AMINO ACID AMINOTRANSFERASE	0	0	1	1
Chain B, AROMATIC AMINO ACID AMINOTRANSFERASE	0	0	1	1
Chain A, AROMATIC AMINO ACID AMINOTRANSFERASE	0	0	1	1
Chain B, AROMATIC AMINO ACID AMINOTRANSFERASE	0	0	1	1
Chain A, AROMATIC AMINO ACID AMINOTRANSFERASE	0	0	1	1
Chain B, AROMATIC AMINO ACID AMINOTRANSFERASE	0	0	1	1
Chain A, AROMATIC AMINO ACID AMINOTRANSFERASE	0	0	1	1
Chain B, AROMATIC AMINO ACID AMINOTRANSFERASE	0	0	1	1
Chain A, AROMATIC AMINO ACID AMINOTRANSFERASE	0	0	1	1
Chain B, AROMATIC AMINO ACID AMINOTRANSFERASE	0	0	1	1
Chain A, AROMATIC AMINO ACID AMINOTRANSFERASE	0	0	1	1
Chain B, AROMATIC AMINO ACID AMINOTRANSFERASE	0	0	1	1
Chain A, AROMATIC AMINO ACID AMINOTRANSFERASE	0	0	1	1
Chain B, AROMATIC AMINO ACID AMINOTRANSFERASE	0	0	1	1
Chain A, AROMATIC AMINO ACID AMINOTRANSFERASE	0	0	1	1
Chain B, AROMATIC AMINO ACID AMINOTRANSFERASE	0	0	1	1
Chain A, AROMATIC AMINO ACID AMINOTRANSFERASE	0	0	1	1
Chain B, AROMATIC AMINO ACID AMINOTRANSFERASE	0	0	1	1
survival motor neuron protein isoform d	34	0	0	34
Histone deacetylase 3	0	15	1	21
Histone deacetylase 4	0	13	2	21
Histone deacetylase 1	0	16	4	25
Histone deacetylase 7	0	13	2	20
Histone deacetylase 2	0	15	3	23
Polyamine deacetylase HDAC10	0	11	1	17
Histone deacetylase 11	0	11	1	17
Histone deacetylase 8	0	14	2	21
NAD-dependent protein deacylase sirtuin-5, mitochondrial	0	5	0	5
Histone deacetylase 6	0	16	3	24
Histone deacetylase 9	0	13	1	19
Histone deacetylase 5	0	13	1	19
5-hydroxytryptamine receptor 1A	0	15	8	25
D(2) dopamine receptor	0	24	3	27
5-hydroxytryptamine receptor 2A	0	19	5	25
5-hydroxytryptamine receptor 1A	0	31	6	40
5-hydroxytryptamine receptor 1B	0	5	2	7
5-hydroxytryptamine receptor 2A	0	25	4	31
5-hydroxytryptamine receptor 2C	0	30	2	33
5-hydroxytryptamine receptor 1B	0	20	2	23
5-hydroxytryptamine receptor 7	0	9	2	11
5-hydroxytryptamine receptor 7	0	10	2	12
5-hydroxytryptamine receptor 5A	0	3	0	3
5-hydroxytryptamine receptor 6	0	21	1	22
5-hydroxytryptamine receptor 7	0	11	0	12
5-hydroxytryptamine receptor 1D	0	1	0	1
Chain A, Deoxycytidine kinase	0	1	0	1
Chain A, Deoxycytidine kinase	0	1	0	1
Fumarate hydratase	24	0	0	24
EWS/FLI fusion protein	40	0	0	40
polyprotein	24	0	0	24
Deoxycytidine kinase	0	1	2	5
Canalicular multispecific organic anion transporter 1	0	2	0	3
15-lipoxygenase, partial	23	0	0	23
USP1 protein, partial	42	0	0	42
glucocerebrosidase	11	0	0	11
lethal factor (plasmid)	26	0	0	26
Glutamate receptor 1	0	8	3	11
Glutamate receptor 2	0	8	3	11
Glutamate receptor 3	0	6	2	8
Glutamate receptor 4	0	8	2	10
Nrf2	2	0	0	2
ATAD5 protein, partial	39	0	0	39
luciferase	2	0	0	2
Parkin	9	0	0	9
pyruvate kinase	4	0	0	4
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)	8	0	0	8
beta-2 adrenergic receptor	4	0	0	4
cytochrome P450 2D6 isoform 1	19	0	0	19
NPC intracellular cholesterol transporter 1 precursor	11	0	0	11
cellular tumor antigen p53 isoform a	18	0	0	18
cytochrome P450 2C19 precursor	23	0	0	23
cytochrome P450 2C9 precursor	19	0	0	19
atrial natriuretic peptide receptor 1 precursor	6	0	0	6
atrial natriuretic peptide receptor 2 precursor	8	0	0	8
ras-related protein Rab-9A	11	0	0	11
peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	13	0	0	13
pyruvate kinase PKM isoform b	4	0	0	4
Metabotropic glutamate receptor 8	0	3	0	3
Metabotropic glutamate receptor 6	0	2	4	7
Integrin beta-3	13	3	1	17
Integrin alpha-IIb	13	3	1	17
Luciferin 4-monooxygenase	0	2	0	2
Cytochrome P450 3A4	0	21	1	25
Ornithine decarboxylase	4	0	0	5
Cytochrome P450 2D6	0	16	2	18
Metabotropic glutamate receptor 1	0	3	1	4
Histamine H2 receptor	29	4	0	36
Glutamate receptor ionotropic, NMDA 2B	0	7	0	7
Metabotropic glutamate receptor 1	0	4	3	8
Metabotropic glutamate receptor 2	0	2	3	6
Metabotropic glutamate receptor 7	0	2	1	4
Metabotropic glutamate receptor 3	0	2	1	4
Metabotropic glutamate receptor 4	0	2	2	5
Amine oxidase [flavin-containing] A	0	1	0	1
phosphoglycerate kinase	2	0	0	2
2,3-bisphosphoglycerate-independent phosphoglycerate mutase	1	0	0	1
polyunsaturated fatty acid lipoxygenase ALOX12	8	0	0	8
DNA polymerase kappa isoform 1	27	0	0	27
caspase-1 isoform alpha precursor	7	0	0	7
Polyunsaturated fatty acid lipoxygenase ALOX15B	13	0	0	13
Aromatase	0	6	0	6
Aldo-keto reductase family 1 member B1	0	4	0	4
Caspase-7	6	0	0	6
Dual specificity tyrosine-phosphorylation-regulated kinase 1A	0	4	2	6
Serine/threonine-protein kinase Chk1	0	2	2	4
3-phosphoinositide-dependent protein kinase 1	0	1	0	1
Cyclin-dependent kinase 1	0	4	2	6
Cyclin-dependent kinase 4	0	2	2	4
Cyclin-A2	0	4	0	4
G1/S-specific cyclin-D1	0	2	0	2
Cyclin-dependent kinase 2	0	5	3	8
Tyrosyl-DNA phosphodiesterase 1	0	1	0	1
mu-type opioid receptor isoform MOR-1	0	0	3	3
5-hydroxytryptamine receptor 2A	0	0	3	3
5-hydroxytryptamine receptor 2C	0	15	4	20
Neuronal acetylcholine receptor subunit alpha-4	4	9	2	15
Cytochrome P450 2C9	0	20	1	21
Neuronal acetylcholine receptor subunit beta-2	4	9	2	15
Alpha-1B adrenergic receptor	0	23	2	25
Translocator protein	0	2	1	4
D	0	8	0	8
D(3) dopamine receptor	0	6	0	6
Alpha-2B adrenergic receptor	0	10	1	12
D(2) dopamine receptor	0	1	0	1
Alpha-2C adrenergic receptor	0	10	1	12
Alpha-2A adrenergic receptor	0	10	1	12
Alpha-1D adrenergic receptor	0	16	2	19
Sodium-dependent dopamine transporter	0	10	2	12
Alpha-1D adrenergic receptor	0	16	2	20
5-hydroxytryptamine receptor 1D	0	2	0	5
5-hydroxytryptamine receptor 1D	0	5	2	8
5-hydroxytryptamine receptor 1F	0	5	2	8
5-hydroxytryptamine receptor 2B	0	14	4	18
Alpha-1A adrenergic receptor	0	8	3	13
Alpha-1B adrenergic receptor	0	6	2	10
5-hydroxytryptamine receptor 3A	0	5	2	7
Alpha-1A adrenergic receptor	0	27	3	30
D	0	1	0	1
5-hydroxytryptamine receptor 2A	0	1	0	1
Sigma non-opioid intracellular receptor 1	0	24	1	25
5-hydroxytryptamine receptor 3B	0	5	2	7
Lysosomal alpha-glucosidase	0	1	0	1
Transporter	0	9	0	9
Chain A, Avidin	0	0	2	2
Chain A, Avidin	0	0	2	2
Chain B, Avidin	0	0	2	2
acetylcholinesterase	29	0	0	29
dopamine D1 receptor	6	0	0	6
pregnane X receptor	13	0	0	13
peripheral myelin protein 22	39	0	0	39
Solute carrier family 22 member 6	0	4	0	4
Putative glycosyltransferase WbgO	0	0	0	1
Cannabinoid receptor 1	0	8	3	11
Killer cell lectin-like receptor subfamily B member 1A	0	1	0	1
Early activation antigen CD69	0	1	0	1
Chain A, MTA/SAH nucleosidase	0	1	0	1
Chain A, Ribosome-inactivating protein alpha-trichosanthin	0	0	1	1
Chain A, Ricin A chain	0	0	1	1
Chain A, Ribosome-inactivating protein 3	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
nuclear factor erythroid 2-related factor 2 isoform 2	29	0	0	30
importin subunit beta-1 isoform 1	11	0	0	11
snurportin-1	11	0	0	11
tumor susceptibility gene 101 protein	3	0	0	3
GTP-binding nuclear protein Ran isoform 1	7	0	0	7
Bile salt export pump	0	67	0	67
Heat shock protein HSP 90-beta	0	2	0	2
Protein mono-ADP-ribosyltransferase PARP15	0	3	0	3
Leucine-rich repeat serine/threonine-protein kinase 2	0	2	0	2
Chain A, Membrane lipoprotein tmpC	0	0	2	2
Chain A, Membrane lipoprotein tmpC	0	0	2	2
Chain A, Membrane lipoprotein tmpC	0	0	2	2
Chain A, Structure of PAE2307 in complex with adenosine	0	0	1	1
Chain B, Structure of PAE2307 in complex with adenosine	0	0	1	1
Chain A, ADENOSINE RECEPTOR A2A	0	1	0	1
Chain A, ADENOSINE RECEPTOR A2A	0	1	0	1
Chain A, tRNA (guanine-N(1)-)-methyltransferase	0	0	1	1
Chain A, Uncharacterized protein MJ0883	0	0	1	1
signal transducer and activator of transcription 6, interleukin-4 induced	1	0	0	1
NPYLR7B	0	0	2	2
glycogen synthase kinase-3 beta isoform 1	0	0	1	1
high affinity choline transporter 1 isoform a	0	1	0	1
Sodium/nucleoside cotransporter 1	0	4	0	4
Calcium dependent protein kinase	0	1	0	1
Mitogen-activated protein kinase kinase kinase 7	0	0	1	1
Sodium/nucleoside cotransporter 2	0	5	0	5
Rap guanine nucleotide exchange factor 3	9	0	0	9
Purine nucleoside phosphorylase	0	3	0	4
Epidermal growth factor receptor	0	8	2	10
Phosphoglycerate kinase 1	0	2	0	2
Adenosine deaminase	0	0	0	1
Avidin	0	0	1	1
Adenosine deaminase	0	0	0	1
Glyceraldehyde-3-phosphate dehydrogenase	0	3	0	3
Receptor tyrosine-protein kinase erbB-2	0	2	0	2
Insulin receptor	0	0	2	3
Phosphoglycerate kinase 2	0	2	0	2
Heat shock protein HSP 90-alpha	0	3	2	5
Platelet-derived growth factor receptor beta	0	0	2	3
Adenosine receptor A3	0	15	4	20
Heat shock 70 kDa protein 1A	0	1	0	1
Heat shock cognate 71 kDa protein	0	0	1	1
Fibroblast growth factor receptor 1	0	0	2	3
Inosine-5'-monophosphate dehydrogenase 2	0	1	2	3
Endoplasmin	0	2	2	4
Inosine-5'-monophosphate dehydrogenase 1	0	1	0	1
Fibroblast growth factor receptor 2	0	0	0	1
Fibroblast growth factor receptor 4	0	0	0	1
Fibroblast growth factor receptor 3	0	0	0	1
Streptavidin	0	0	2	2
Adenosylhomocysteinase	0	1	0	3
Adenylate kinase 2, mitochondrial	0	1	0	1
Adenylate kinase isoenzyme 1	0	1	0	1
Adenosine receptor A1	0	2	2	6
Adenosine kinase	0	0	2	3
Adenosine deaminase	0	0	0	1
Equilibrative nucleoside transporter 2	0	4	0	4
Histone-lysine N-methyltransferase, H3 lysine-79 specific	0	3	1	4
Equilibrative nucleoside transporter 1	0	7	0	7
Solute carrier family 28 member 3	0	4	0	4
Adenosine kinase	0	1	0	2
5-methylthioadenosine/S-adenosylhomocysteine deaminase	0	0	0	2
Adenosine transporter 1	0	1	0	2
Kinesin-like protein KIF11	0	1	0	1
Smad3	25	0	0	25
caspase 7, apoptosis-related cysteine protease	20	0	0	20
nonstructural protein 1	10	0	0	10
67.9K protein	30	0	0	30
caspase-3	20	0	0	20
thyroid stimulating hormone receptor	29	0	0	29
thyrotropin-releasing hormone receptor	9	0	0	9
ubiquitin-conjugating enzyme E2 N	0	2	0	2
urokinase-type plasminogen activator precursor	16	0	0	16
plasminogen precursor	16	0	0	16
urokinase plasminogen activator surface receptor precursor	16	0	0	16
neuropeptide S receptor isoform A	14	0	0	14
Phospholipase D2	0	1	0	1
Estrogen receptor	0	6	2	10
Estrogen-related receptor gamma	0	3	1	4
Phospholipase D1	0	2	0	2
Estrogen receptor beta	0	5	2	7
Chain A, Cruzipain	12	0	0	12
Solute carrier family 22 member 2	0	7	0	11
Solute carrier family 22 member 1	0	16	0	20
Polyamine oxidase 1	0	1	0	1
Solute carrier family 22 member 3	0	6	0	7
Solute carrier family 22 member 3	0	3	0	5
Nischarin	0	3	0	3
Solute carrier family 22 member 1	0	8	0	11
Deoxyhypusine synthase	0	1	0	1
Solute carrier family 22 member 2	0	5	0	8
Carbonic anhydrase 1	0	18	0	29
Carbonic anhydrase 2	0	19	2	33
Alanine racemase, biosynthetic	0	0	0	1
Proton-coupled amino acid transporter 1	0	9	0	10
Adenosine deaminase	0	0	0	1
Carbonic anhydrase 4	0	2	0	5
Glutamate receptor ionotropic, NMDA 2D	0	4	0	4
Glutamate receptor ionotropic, NMDA 3B	0	4	0	4
Glutamate receptor 3	1	8	4	14
Glutamate receptor 4	1	8	4	14
Glutamate receptor ionotropic, kainate 1	0	8	2	11
Glutamate receptor 1	0	1	1	2
Glutamate receptor 2	0	1	0	1
Glutamate receptor ionotropic, kainate 1	0	5	2	7
Glutamate receptor ionotropic, kainate 2	0	8	3	12
Excitatory amino acid transporter 1	0	6	0	7
Excitatory amino acid transporter 2	0	5	0	6
Excitatory amino acid transporter 3	0	5	0	6
Glutamate receptor ionotropic, kainate 4	0	6	0	7
Glutamate receptor ionotropic, NMDA 1	0	6	0	6
Glutamate receptor ionotropic, NMDA 2A	0	6	0	6
Glutamate receptor ionotropic, kainate 2	0	5	2	7
Glutamate receptor ionotropic, kainate 3	0	4	0	4
Glutamate receptor ionotropic, NMDA 2C	0	4	0	4
Glutamate receptor ionotropic, kainate 4	0	2	0	2
Glutamate receptor ionotropic, kainate 5	0	4	0	4
Glutamate receptor ionotropic, kainate 5	0	6	0	7
Glutamate receptor ionotropic, NMDA 3A	0	4	0	4
Glutamate receptor 4	0	1	0	1
Glutamate receptor 3	0	1	0	1
3-hydroxy-3-methylglutaryl-coenzyme A reductase	0	5	0	5
3-hydroxy-3-methylglutaryl-coenzyme A reductase	0	2	0	2
alpha-galactosidase	7	0	0	7
nuclear receptor subfamily 1, group I, member 2	9	0	0	9
Gamma-aminobutyric acid receptor subunit alpha-1	0	5	0	8
Gamma-aminobutyric acid receptor subunit beta-1	0	5	0	8
Gamma-aminobutyric acid receptor subunit alpha-2	0	5	0	8
Gamma-aminobutyric acid receptor subunit alpha-3	0	5	0	8
Gamma-aminobutyric acid receptor subunit alpha-1	0	15	8	23
Gamma-aminobutyric acid receptor subunit gamma-2	0	15	7	22
Gamma-aminobutyric acid receptor subunit alpha-4	0	5	0	8
Gamma-aminobutyric acid receptor subunit gamma-2	0	5	0	8
Sodium- and chloride-dependent GABA transporter 1	0	4	0	4
Gamma-aminobutyric acid receptor subunit beta-3	0	14	6	20
Sodium- and chloride-dependent GABA transporter 2	0	5	0	5
Sodium- and chloride-dependent GABA transporter 3	0	4	0	4
Alpha-synuclein	10	1	0	11
Gamma-aminobutyric acid receptor subunit alpha-2	0	12	5	17
Gamma-aminobutyric acid receptor subunit beta-2	0	13	6	19
Sodium- and chloride-dependent betaine transporter	0	4	0	4
ATP-binding cassette sub-family C member 3	0	46	0	46
Multidrug resistance-associated protein 4	0	47	0	51
Thromboxane-A synthase	0	2	0	2
Prostaglandin E2 receptor EP3 subtype	0	1	0	1
Prostaglandin E2 receptor EP4 subtype	0	1	1	2
Prostaglandin E2 receptor EP1 subtype	0	1	0	1
Prostacyclin receptor	0	1	1	2
Nuclear receptor subfamily 4 group A member 2	0	0	4	4
Solute carrier organic anion transporter family member 2A1	0	0	0	2
Nuclear receptor subfamily 4 group A member 2	0	0	1	1
Nuclear receptor subfamily 4 group A member 2	0	0	1	1
Prostaglandin E2 receptor EP2 subtype	0	1	1	2
Canalicular multispecific organic anion transporter 1	0	45	0	46
Solute carrier organic anion transporter family member 2A1	0	1	0	2
Solute carrier organic anion transporter family member 2B1	0	1	0	1
Solute carrier organic anion transporter family member 3A1	0	0	0	1
Androgen receptor	0	10	0	10
Cannabinoid receptor 1	0	9	4	19
Cannabinoid receptor 2	0	8	4	17
cytochrome P450 2D6	36	0	0	36
serine/threonine-protein kinase mTOR isoform 1	14	0	0	14
Voltage-dependent L-type calcium channel subunit alpha-1F	0	8	0	8
5-hydroxytryptamine receptor 4	0	20	0	20
Albumin	0	0	5	5
High affinity nerve growth factor receptor	0	1	4	5
Aldo-keto reductase family 1 member B1	0	20	0	20
Muscarinic acetylcholine receptor M2	0	20	4	29
Muscarinic acetylcholine receptor M4	0	20	3	27
Muscarinic acetylcholine receptor M1	0	8	3	15
Muscarinic acetylcholine receptor M3	0	6	3	12
Muscarinic acetylcholine receptor M4	0	7	2	12
Muscarinic acetylcholine receptor M5	0	7	2	12
Muscarinic acetylcholine receptor M5	0	19	3	25
Alpha-2A adrenergic receptor	0	17	4	22
Muscarinic acetylcholine receptor M2	0	7	3	14
Muscarinic acetylcholine receptor M1	0	21	4	30
Angiotensin-converting enzyme	0	14	0	14
Alpha-2B adrenergic receptor	0	18	3	22
Alpha-2C adrenergic receptor	0	13	4	18
Muscarinic acetylcholine receptor M3	0	20	4	27
D(1A) dopamine receptor	0	13	2	15
D(1B) dopamine receptor	0	3	0	3
UDP-glucuronosyltransferase 1A4	0	1	0	4
Histamine H2 receptor	0	8	0	8
5-hydroxytryptamine receptor 6	0	3	2	5
Histamine H1 receptor	0	2	0	2
Sodium-dependent serotonin transporter	0	25	4	29
5-hydroxytryptamine receptor 5A	0	3	2	5
5-hydroxytryptamine receptor 5B	0	3	2	5
Histamine H1 receptor	0	12	0	12
D(3) dopamine receptor	0	15	1	16
Sodium channel protein type 1 subunit alpha	0	4	0	4
Sodium channel protein type 4 subunit alpha	0	5	0	7
UDP-glucuronosyltransferase 1A3	0	0	0	2
5-hydroxytryptamine receptor 2B	0	32	2	35
D(1A) dopamine receptor	6	0	0	6
Voltage-dependent N-type calcium channel subunit alpha-1B	0	2	0	2
Sodium channel protein type 7 subunit alpha	0	3	0	3
Voltage-dependent L-type calcium channel subunit alpha-1D	0	8	0	8
Potassium voltage-gated channel subfamily H member 2	0	33	0	34
Voltage-dependent L-type calcium channel subunit alpha-1S	0	8	0	8
Sodium channel protein type 5 subunit alpha	0	6	0	6
Sodium channel protein type 9 subunit alpha	0	7	0	7
Sigma non-opioid intracellular receptor 1	0	6	2	8
5-hydroxytryptamine receptor 4	0	3	2	5
Nuclear receptor subfamily 3 group C member 3	0	14	0	14
Sodium channel protein type 2 subunit alpha	0	4	0	4
Sodium channel protein type 3 subunit alpha	0	4	0	4
Sodium channel protein type 11 subunit alpha	0	3	0	3
Sodium channel protein type 8 subunit alpha	0	3	0	3
Histamine H3 receptor	0	6	0	6
Sodium channel protein type 10 subunit alpha	0	3	0	3
Phenylethanolamine N-methyltransferase	0	4	0	4
Substance-P receptor	0	1	0	1
Beta-2 adrenergic receptor	0	3	2	6
Sigma non-opioid intracellular receptor 1	0	6	2	8
Fatty-acid amide hydrolase 1	0	7	0	7
Fatty-acid amide hydrolase 1	0	2	0	3
Potassium channel subfamily K member 3	0	1	0	1
Fatty acid-binding protein, liver	0	4	0	4
Cannabinoid receptor 1	0	3	1	4
Cannabinoid receptor 2	0	1	1	2
Fatty-acid amide hydrolase 1	0	7	0	8
Fatty acid-binding protein 5	0	0	2	2
Corticotropin-releasing factor receptor 2	0	1	0	1
Lanosterol 14-alpha demethylase	0	3	0	3
Potassium channel subfamily K member 2	0	1	0	1
Transient receptor potential cation channel subfamily V member 1	0	2	3	6
Cannabinoid receptor 2	0	2	1	3
Transient receptor potential cation channel subfamily V member 2	0	3	1	4
Chain A, BCL-2-RELATED PROTEIN A1	0	0	1	2
PAX8	0	0	0	4
Hsf1 protein	0	0	3	5
hepatitis C virus polyprotein	1	0	0	1
heat shock protein 90	0	0	1	1
caspase recruitment domain family, member 15	0	1	0	1
Spike glycoprotein	0	1	4	5
Replicase polyprotein 1ab	0	2	4	6
receptor-interacting serine/threonine-protein kinase 2 isoform 1	0	1	0	1
bcl-2-like protein 11 isoform 1	0	0	1	1
Transmembrane protease serine 2	0	1	4	5
Bcl-2-like protein 11	0	0	0	1
Glucose transporter	0	2	0	2
Hexose transporter 1	0	2	0	2
Procathepsin L	0	1	4	5
Replicase polyprotein 1a	0	1	4	5
Replicase polyprotein 1ab	0	1	4	5
Replicase polyprotein 1ab	0	3	4	7
Replicase polyprotein 1ab	0	4	4	8
Solute carrier family 2, facilitated glucose transporter member 1	0	2	1	3
Spike glycoprotein	28	1	4	33
Angiotensin-converting enzyme 2	0	1	4	5
Beta lactamase (plasmid)	0	1	0	1
huntingtin isoform 2	8	0	0	8
DNA polymerase catalytic subunit	0	1	0	1
DNA polymerase catalytic subunit	0	1	0	1
DNA polymerase beta	0	2	0	2
DNA polymerase beta	0	1	0	1
DNA polymerase catalytic subunit	0	1	0	1
DNA polymerase catalytic subunit	0	1	0	1
DNA polymerase alpha catalytic subunit	0	1	1	2
DNA polymerase delta catalytic subunit	0	1	0	1
DNA polymerase catalytic subunit	0	1	0	1
DNA polymerase subunit gamma-1	0	1	0	1
DNA polymerase lambda	0	1	0	1
cAMP-specific 3',5'-cyclic phosphodiesterase 4A	0	8	2	11
Cytochrome P450 2C19	0	15	1	17
cAMP-specific 3',5'-cyclic phosphodiesterase 4C	0	6	0	6
Carboxylic ester hydrolase	0	2	0	2
Chain A, ADIPOCYTE LIPID-BINDING PROTEIN	0	0	1	1
Chain A, SERUM ALBUMIN	0	0	1	1
Chain A, SERUM ALBUMIN	0	0	1	1
ubiquitin carboxyl-terminal hydrolase 2 isoform a	8	0	0	8
lethal(3)malignant brain tumor-like protein 1 isoform I	5	0	0	5
DNA dC->dU-editing enzyme APOBEC-3G isoform 1	5	0	0	5
Prostaglandin G/H synthase 1	0	4	0	5
Trypsin	0	3	0	3
Coagulation factor VII	0	5	0	5
60 kDa chaperonin	0	3	0	3
60 kDa heat shock protein, mitochondrial	0	3	0	3
Tissue factor	0	6	0	6
Fatty acid-binding protein, adipocyte	0	3	1	4
Prostaglandin G/H synthase 2	0	9	1	11
10 kDa heat shock protein, mitochondrial	0	3	0	3
Calmodulin	0	0	1	2
Disintegrin and metalloproteinase domain-containing protein 17	5	2	0	7
Prostaglandin G/H synthase 2	0	4	0	5
Fatty acid-binding protein 5	0	2	0	2
Thiosulfate sulfurtransferase	0	3	0	3
60 kDa chaperonin	0	3	0	3
10 kDa chaperonin	0	3	0	3
Solute carrier organic anion transporter family member 1B3	0	6	0	7
Cytosolic phospholipase A2 gamma	0	1	0	1
Solute carrier organic anion transporter family member 1B1	0	7	0	8
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN	0	0	3	3
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN	0	0	3	3
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN	0	0	3	3
Nitric oxide synthase, endothelial	0	1	0	3
Nitric oxide synthase, brain	0	2	0	3
Nitric oxide synthase, brain	0	2	0	3
Nitric oxide synthase, inducible	0	2	0	3
Nitric oxide synthase, inducible	0	2	1	5
Cationic amino acid transporter 3	0	2	0	2
5-hydroxytryptamine receptor 3E	0	1	0	1
PPM1D protein	16	0	0	16
potassium voltage-gated channel subfamily H member 2 isoform d	23	0	0	23
transcriptional regulator ERG isoform 3	11	0	0	11
5-hydroxytryptamine receptor 3A	0	2	1	3
5-hydroxytryptamine receptor 3B	0	1	0	1
ATP-dependent translocase ABCB1	0	23	1	31
D(4) dopamine receptor	0	9	0	9
D(4) dopamine receptor	0	4	0	4
Histamine H1 receptor	0	4	0	4
5-hydroxytryptamine receptor 3A	0	1	0	1
3-hydroxy-3-methylglutaryl-coenzyme A reductase	0	4	0	4
5-hydroxytryptamine receptor 3D	0	1	0	1
Multidrug and toxin extrusion protein 2	0	4	0	4
5-hydroxytryptamine receptor 3C	0	1	0	1
Multidrug and toxin extrusion protein 1	0	8	0	8
Chain A, Hyaluronidase, phage associated	0	1	0	1
Polyphenol oxidase 2	0	5	0	8
Pancreatic alpha-amylase	0	2	0	2
Albumin	0	1	0	1
Urease	0	1	0	1
Prolyl 4-hydroxylase subunit alpha-1	0	0	0	1
Tyrosinase	0	4	0	5
Hyaluronate lyase	0	1	0	1
Prolyl hydroxylase EGLN2	0	0	0	1
Egl nine homolog 1	0	0	0	1
Prolyl hydroxylase EGLN3	0	0	0	1
Hypoxia-inducible factor 1-alpha inhibitor	0	0	0	1
Solute carrier family 23 member 1	0	1	0	1
Neutral amino acid transporter A	0	3	0	3
Neutral amino acid transporter B(0)	0	3	0	3
Carbonic anhydrase-like protein, putative	0	0	0	7
Amino acid transporter	0	3	0	3
Excitatory amino acid transporter 4	0	2	0	2
Glutamate transporter homolog	0	0	2	2
Chain A, Phospholipase A2 isoform 3	0	0	1	1
GTP-binding protein (rab7)	0	0	1	1
ras protein, partial	0	0	1	1
Rac1 protein	0	0	1	1
cell division cycle 42 (GTP binding protein, 25kDa), partial	0	0	1	1
Prostaglandin-H2 D-isomerase	0	1	0	1
Prostaglandin G/H synthase 2	0	1	0	1
Fatty acid-binding protein, liver	0	2	0	2
Myeloperoxidase	0	2	0	2
Prostaglandin G/H synthase 1	0	4	1	5
Seed linoleate 13S-lipoxygenase-1	0	2	0	2
Glutathione hydrolase 1 proenzyme	0	1	0	1
Prostaglandin G/H synthase 1	0	8	0	8
Substance-P receptor	0	1	0	1
Urotensin-2 receptor	0	1	0	1
4-aminobutyrate aminotransferase, mitochondrial	0	1	0	1
Ras-related protein Rab-2A	0	0	1	1
Rho-associated protein kinase 2	0	1	0	1
Nicotinate phosphoribosyltransferase	0	2	0	2
Solute carrier family 22 member 20	0	6	0	6
Solute carrier family 22 member 6	0	6	0	6
cystic fibrosis transmembrane conductance regulator	0	2	0	2
short transient receptor potential channel 6 isoform 1	0	0	1	1
Muscarinic acetylcholine receptor M1	0	1	2	5
Muscarinic acetylcholine receptor M4	0	2	1	4
Muscarinic acetylcholine receptor	0	3	1	5
hemoglobin subunit beta	3	0	0	3
DNA (cytosine-5)-methyltransferase 1	0	6	0	6
Histone-lysine N-methyltransferase EHMT2	0	8	1	10
Carbonic anhydrase 4	0	12	0	17
Carbonic anhydrase	0	6	0	9
Carbonic anhydrase 15	0	7	0	10
Gamma-aminobutyric acid type B receptor subunit 2	0	2	3	5
Gamma-aminobutyric acid type B receptor subunit 2	0	4	0	4
Gamma-aminobutyric acid type B receptor subunit 1	0	2	3	5
Gamma-aminobutyric acid type B receptor subunit 1	0	3	0	3
Gamma-aminobutyric acid receptor subunit pi	0	12	0	12
Gamma-aminobutyric acid receptor subunit delta	0	12	0	12
Gamma-aminobutyric acid receptor subunit beta-1	0	12	3	15
Gamma-aminobutyric acid receptor subunit alpha-5	0	12	6	18
Gamma-aminobutyric acid receptor subunit alpha-3	0	12	5	17
Gamma-aminobutyric acid receptor subunit alpha-4	0	12	3	15
Gamma-aminobutyric acid receptor subunit epsilon	0	12	0	12
Gamma-aminobutyric acid receptor subunit alpha-6	0	12	3	15
Gamma-aminobutyric acid receptor subunit gamma-1	0	12	0	12
Gamma-aminobutyric acid receptor subunit gamma-3	0	12	0	12
Gamma-aminobutyric acid receptor subunit theta	0	12	0	12
15-hydroxyprostaglandin dehydrogenase [NAD(+)]	0	1	0	1
Chain A, Betaine ABC transporter permease and substrate binding protein	0	0	1	1
Chain A, Osmoprotection protein (ProX)	0	0	1	1
Chain A, Glycine betaine/carnitine/choline-binding protein	0	0	2	2
Chain A, Glycine betaine/carnitine/choline-binding protein	0	0	2	2
Chain A, Glycine betaine/carnitine/choline-binding protein	0	0	2	2
Chain A, Glycine betaine/carnitine/choline-binding protein	0	0	2	2
Bile salt export pump	0	10	0	10
Chain A, Avidin	0	0	1	1
Chain A, Protein (streptavidin)	0	0	1	1
Chain B, Protein (streptavidin)	0	0	1	1
Chain A, Streptavidin	0	0	1	1
Chain D, Streptavidin	0	0	1	1
Chain A, Streptavidin	0	0	1	1
Chain D, Streptavidin	0	0	1	1
Chain A, Streptavidin	0	0	1	1
Chain D, Streptavidin	0	0	1	1
Chain A, Streptavidin Complex With Biotin	0	0	1	1
Chain D, Circularly Permuted Core-streptavidin E51/a46	0	0	1	1
Chain A, Core-streptavidin	0	0	1	1
Chain D, Core-streptavidin	0	0	1	1
Chain A, Core-streptavidin	0	0	1	1
Chain D, Core-streptavidin	0	0	1	1
Chain A, Core-streptavidin	0	0	1	1
Chain D, Core-streptavidin	0	0	1	1
Chain A, Core-streptavidin	0	0	1	1
Chain D, Core-streptavidin	0	0	1	1
Chain A, Avidin	0	0	1	1
Chain A, Streptavidin	0	0	1	1
Chain B, Streptavidin	0	0	1	1
Chain A, Streptavidin	0	0	1	1
Chain B, Streptavidin	0	0	1	1
nonstructural protein 1	0	1	0	1
green fluorescent protein, partial	0	1	0	1
insulin-degrading enzyme isoform 1	0	0	1	1
Receptor-type tyrosine-protein phosphatase beta	0	0	0	1
Chain A, Estrogen-related receptor gamma	0	0	1	1
Chain A, Estrogen-related receptor gamma	0	0	1	1
Chain A, Estrogen-related receptor gamma	0	0	1	1
Chain A, Estrogen-related receptor gamma	0	0	1	1
GALC protein	6	0	0	6
GTPase KRas	0	0	1	1
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1	0	4	0	4
Androgen receptor	0	1	0	1
Polyunsaturated fatty acid lipoxygenase ALOX15	0	6	0	6
GTP-binding protein Rheb	0	0	1	1
Potassium voltage-gated channel subfamily KQT member 3	0	0	1	1
Potassium voltage-gated channel subfamily KQT member 2	0	0	1	1
UDP-glucuronosyltransferase 2B7	0	2	0	5
Potassium voltage-gated channel subfamily KQT member 4	0	0	1	1
Calcium-activated potassium channel subunit alpha-1	0	0	1	1
Potassium voltage-gated channel subfamily KQT member 5	0	0	1	1
Chain H, Proteasome component PUP1	0	1	0	1
Chain I, Proteasome component PUP3	0	1	0	1
Chain K, Proteasome component PRE2	0	1	0	1
Chain L, Proteasome component C5	0	1	0	1
Chain K, Proteasome component PRE2	0	1	0	1
Chain L, Proteasome component C5	0	1	0	1
Proteasome subunit beta type-11	0	1	0	1
26S proteasome non-ATPase regulatory subunit 11	0	1	0	1
26S proteasome non-ATPase regulatory subunit 12	0	1	0	1
26S proteasome non-ATPase regulatory subunit 14	0	1	0	1
Proteasome subunit alpha type-7	0	1	0	1
26S proteasome non-ATPase regulatory subunit 3	0	1	0	1
Carbonic anhydrase 12	0	5	0	10
Prothrombin	0	2	2	5
Chymotrypsinogen A	0	1	0	1
Carbonic anhydrase 3	0	5	0	8
Cathepsin B	0	1	0	1
Neutrophil elastase	0	5	0	5
Cathepsin G	0	2	0	2
Lysosomal protective protein	0	1	0	1
Chymotrypsinogen B	0	2	0	2
26S proteasome regulatory subunit 6A	0	1	0	1
Nuclear factor NF-kappa-B p105 subunit	0	1	0	1
Proteasome subunit beta type-1	0	1	0	2
Carbonic anhydrase 6	0	6	0	11
Chymase	0	1	0	1
Proteasome subunit alpha type-1	0	1	0	1
Proteasome subunit alpha type-2	0	1	0	1
Proteasome subunit alpha type-3	0	1	0	1
Proteasome subunit alpha type-4	0	1	0	1
Proteasome subunit beta type-8	0	1	0	1
Proteasome subunit beta type-8	0	1	0	1
Proteasome subunit beta type-9	0	1	0	1
Proteasome subunit alpha type-5	0	1	0	1
Proteasome subunit beta type-4	0	1	0	1
Proteasome subunit beta type-6	0	1	0	1
Proteasome subunit beta type-5	0	4	0	5
Carbonic anhydrase 5A, mitochondrial	0	7	1	13
26S proteasome regulatory subunit 7	0	1	0	1
Lon protease homolog, mitochondrial	0	1	0	1
Proteasome subunit beta type-10	0	1	0	1
Carbonic anhydrase 7	0	5	0	10
26S proteasome regulatory subunit 6B	0	1	2	3
26S proteasome non-ATPase regulatory subunit 8	0	1	0	1
Proteasome subunit beta type-3	0	1	0	1
Proteasome subunit beta type-2	0	1	0	2
26S proteasome non-ATPase regulatory subunit 7	0	1	0	1
26S proteasome non-ATPase regulatory subunit 4	0	1	0	1
26S proteasome complex subunit SEM1	0	1	0	1
Proteasome subunit alpha type-6	0	1	0	1
26S proteasome regulatory subunit 4	0	1	0	1
26S proteasome regulatory subunit 8	0	1	0	1
26S proteasome regulatory subunit 10B	0	1	0	1
Beta-carbonic anhydrase 1	0	3	0	3
Nuclear factor NF-kappa-B p100 subunit	0	1	0	1
Transcription factor p65	0	1	0	1
26S proteasome non-ATPase regulatory subunit 2	0	1	0	1
26S proteasome non-ATPase regulatory subunit 6	0	1	0	1
Proteasomal ubiquitin receptor ADRM1	0	1	0	1
Carbonic anhydrase 9	0	7	0	13
ATP-dependent Clp protease proteolytic subunit	0	1	1	2
Carbonic anhydrase 13	0	3	0	4
NACHT, LRR and PYD domains-containing protein 3	0	2	0	2
Proteasome subunit alpha-type 8	0	1	0	1
Proteasome subunit beta type-7	0	1	0	1
26S proteasome non-ATPase regulatory subunit 1	0	1	0	1
Carbonic anhydrase 14	0	5	0	10
26S proteasome non-ATPase regulatory subunit 13	0	1	0	1
Carbonic anhydrase 5B, mitochondrial	0	5	0	10
Nuclear hormone receptor family member daf-12	0	0	1	1
oxysterols receptor LXR-beta isoform 1	0	0	1	1
Thymidine kinase, cytosolic	0	4	0	9
Thymidine phosphorylase	0	0	0	5
Thymidine kinase	0	0	0	3
muscleblind-like protein 1 isoform 1	12	0	0	12
Solute carrier family 12 member 2	0	1	0	1
Carbonic anhydrase 13	0	3	0	7
Chain A, Nitrile Hydratase alpha subunit	0	1	0	1
Chain B, Nitrile Hydratase beta subunit	0	1	0	1
Lysine-specific demethylase 4E	0	3	0	3
Free fatty acid receptor 3	0	0	1	1
Methyl-accepting chemotaxis protein NahY	0	0	1	1
Chain A, Glycogen Phosphorylase	0	1	0	1
Chain A, Glycogen phosphorylase, liver form	0	0	1	1
Chain A, glycogen phosphorylase, liver form	0	0	1	1
Chain A, Glycogen phosphorylase, liver form	0	0	1	1
Chain A, Glycogen phosphorylase, liver form	0	0	1	1
Chain A, Chitinase	0	1	0	1
Potassium channel subfamily K member 2	0	0	2	2
Glycogen phosphorylase, muscle form	0	1	0	1
Cholinesterase	0	6	0	6
Glycogen phosphorylase, liver form	0	1	0	1
Glycogen phosphorylase, muscle form	0	1	0	1
Amine oxidase [flavin-containing] A	0	8	0	8
Acetylcholinesterase	0	11	2	13
Amine oxidase [flavin-containing] B	0	6	0	6
Vasopressin V2 receptor	0	0	0	1
Serine/threonine-protein kinase mTOR	0	3	1	4
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	0	3	0	3
DNA-dependent protein kinase catalytic subunit	0	3	0	3
Adenylate cyclase type 1	0	1	1	3
Chitotriosidase-1	0	1	0	1
Serine-protein kinase ATM	0	3	0	3
Serine/threonine-protein kinase ATR	0	2	1	3
Adenosine receptor A2b	0	1	0	2
Palmitoleoyl-protein carboxylesterase NOTUM	0	2	2	4
Endochitinase B1	0	1	0	1
Broad substrate specificity ATP-binding cassette transporter ABCG2	0	5	0	6
Guanine deaminase	0	1	0	2
Acetylcholinesterase	0	5	0	5
L-lactate dehydrogenase A chain	0	1	0	1
Cytochrome P450 1A1	0	4	0	4
Cytochrome P450 2C11	0	2	0	2
Steroid 17-alpha-hydroxylase/17,20 lyase	0	1	0	1
Cytochrome P450 2B6	0	6	1	7
Cytochrome P450 3A5	0	2	0	2
Cytochrome P450 3A7	0	1	0	1
Caspase-1	0	1	1	2
Mu-type opioid receptor	0	10	1	12
Peroxisome proliferator-activated receptor gamma	0	0	6	6
Delta-type opioid receptor	0	7	1	9
Kappa-type opioid receptor	0	7	1	9
Cholinesterase	0	5	0	5
N-acylethanolamine-hydrolyzing acid amidase	0	2	0	2
Cytochrome P450 1B1	0	3	0	3
Heat sensitive channel TRPV3	0	1	1	2
Sigma intracellular receptor 2	0	1	0	1
Transient receptor potential cation channel subfamily A member 1	0	1	2	3
Transient receptor potential cation channel subfamily M member 8	0	2	0	2
Transient receptor potential cation channel subfamily V member 4	0	1	1	2
G-protein coupled receptor 55	0	0	3	3
Diacylglycerol lipase-alpha	0	2	0	2
Transient receptor potential cation channel subfamily A member 1	0	1	3	4
G-protein coupled receptor 6	0	0	1	1
Transient receptor potential cation channel subfamily M member 8	0	1	0	1
Transient receptor potential cation channel subfamily V member 3	0	1	1	2
Transient receptor potential cation channel subfamily V member 4	0	1	1	2
Transient receptor potential cation channel subfamily V member 2	0	1	1	2
Neuronal acetylcholine receptor subunit alpha-3	0	5	1	6
Neuronal acetylcholine receptor subunit alpha-2	0	3	0	3
Neuronal acetylcholine receptor subunit beta-3	0	2	1	3
Neuronal acetylcholine receptor subunit beta-4	0	5	1	6
Neuronal acetylcholine receptor subunit alpha-5	0	2	0	2
Delta-type opioid receptor	0	5	1	8
Neuronal acetylcholine receptor subunit alpha-6	0	3	1	4
Neuronal acetylcholine receptor subunit alpha-9	0	2	0	2
Neuronal acetylcholine receptor subunit alpha-7	0	6	1	7
Muscarinic acetylcholine receptor M3	0	0	2	5
Muscarinic acetylcholine receptor M2	0	0	1	5
Neuronal acetylcholine receptor subunit alpha-10	0	2	0	2
Vpr	2	0	0	2
Major prion protein	0	0	2	2
Sodium channel protein type 1 subunit alpha	0	2	0	2
Sodium channel protein type 2 subunit alpha	0	5	0	5
Sodium channel protein type 3 subunit alpha	0	2	0	2
Cytochrome P450 2J2	0	8	0	8
Frizzled-8	0	0	1	1
P2X purinoceptor 4	0	1	0	1
histone-lysine N-methyltransferase 2A isoform 2 precursor	12	0	0	12
Chain A, serum paraoxonase	0	1	0	1
Neutrophil cytosol factor 1	0	1	0	1
Poly [ADP-ribose] polymerase tankyrase-2	0	1	0	1
Solute carrier family 22 member 5	0	0	0	2
Solute carrier family 22 member 5	0	0	0	1
Solute carrier family 22 member 16	0	0	0	1
Solute carrier family 22 member 21	0	0	0	1
Solute carrier family 22 member 5	0	0	0	2
Chain A, Protein kinase CK2, alpha Subunit	0	1	0	1
Chain A, PROTEIN KINASE CK2, alpha SUBUNIT	0	1	0	1
Chain A, Protein Kinase Ck2, Alpha Subunit	0	1	0	1
Serine/threonine-protein kinase Sgk1	0	1	0	1
Ribosyldihydronicotinamide dehydrogenase [quinone]	0	3	3	6
Casein kinase II subunit alpha	0	1	0	1
Casein kinase II subunit alpha'	0	4	3	7
Casein kinase II subunit beta	0	4	1	5
Casein kinase II subunit beta	0	1	0	1
Casein kinase II subunit alpha	0	4	2	6
Cyclin-A1	0	2	0	2
Dual specificity mitogen-activated protein kinase kinase 1	0	2	2	4
Ribosomal protein S6 kinase alpha-1	0	1	2	3
Casein kinase II subunit alpha 3	0	4	1	5
Single-stranded DNA cytosine deaminase	2	0	0	2
DNA polymerase eta isoform 1	8	0	0	8
Arginase	0	2	0	2
Pancreatic triacylglycerol lipase	0	1	0	1
Sucrase-isomaltase, intestinal	0	1	0	1
Melatonin receptor type 1A	0	2	2	4
Melatonin receptor type 1B	0	2	2	4
Death-associated protein kinase 1	0	2	0	2
Beta-secretase 1	0	3	0	3
Carbonic anhydrase 3	0	1	0	1
Dihydroorotate dehydrogenase	0	1	0	1
Glycogen synthase kinase-3 beta	0	1	0	1
[Tau protein] kinase	0	1	0	1
Casein kinase 1, delta tv1	0	1	0	1
Cyclin-T1	0	1	0	1
Protein kinase C gamma type	0	2	0	2
Protein kinase C beta type	0	2	2	4
Serine/threonine-protein kinase pim-1	0	2	2	4
Protein kinase C alpha type	0	2	2	4
Dual specificity protein kinase CLK1	0	1	0	1
Protein kinase C-like 1	0	1	0	1
Cyclin-dependent kinase 9	0	1	2	3
Cyclin-dependent-like kinase 5	0	1	2	3
Cyclin-dependent kinase 5 activator 1	0	1	0	1
Dual specificity tyrosine-phosphorylation-regulated kinase 1A	0	2	0	2
Serine/threonine-protein kinase haspin	0	1	0	1
Aurora kinase B	0	1	1	2
MAP kinase-interacting serine/threonine-protein kinase 1	0	1	0	1
MAP kinase-interacting serine/threonine-protein kinase 2	0	1	0	1
Caspase-2	0	0	1	1
parathyroid hormone/parathyroid hormone-related peptide receptor precursor	7	0	0	7
PINK1	3	0	0	3
serine-protein kinase ATM isoform a	2	0	0	2
prostaglandin E2 receptor EP2 subtype	0	0	0	1
serine/threonine-protein kinase PLK1	8	0	0	8
Acetylcholinesterase	0	1	0	1
Carboxylic ester hydrolase	0	1	0	1
Rap guanine nucleotide exchange factor 4	8	0	0	8
ORF73	0	0	1	1
UDP-glucuronosyltransferase 1-6	0	1	0	2
UDP-glucuronosyltransferase 1A1	0	3	0	4
UDP-glucuronosyltransferase 2B10	0	1	0	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Putative Glycine Betaine-binding Abc Transporter Protein	0	0	1	1
Chain A, PUTATIVE GLYCINE BETAINE-BINDING ABC TRANSPORTER PROTEIN	0	0	1	1
Chain A, Choline-binding protein	0	0	1	1
Solute carrier family 22 member 1	0	4	0	6
Solute carrier family 22 member 2	0	2	0	3
Sodium- and chloride-dependent creatine transporter 1	0	1	0	1
Choline O-acetyltransferase	0	2	0	3
High affinity choline transporter 1	0	1	0	1
Sodium-dependent noradrenaline transporter	0	2	0	2
Tryptophan 5-hydroxylase 1	0	2	0	2
Aromatase	0	1	0	1
Sigma intracellular receptor 2	0	3	0	3
Sodium-dependent serotonin transporter	0	2	0	2
Sodium-dependent dopamine transporter	0	4	0	4
Translocator protein	0	2	0	2
Translocator protein	0	2	0	2
Cholecystokinin receptor type A	1	2	0	3
Gastrin/cholecystokinin type B receptor	1	2	0	3
Beta-1 adrenergic receptor	0	1	3	5
Alpha-1B adrenergic receptor	0	0	2	2
Membrane primary amine oxidase	0	1	0	1
Alpha-1A adrenergic receptor	0	1	2	3
D(1B) dopamine receptor	0	3	0	3
Alpha-2B adrenergic receptor	0	0	0	1
Mu-type opioid receptor	0	5	0	5
Alpha-2C adrenergic receptor	0	0	0	1
Alpha-2A adrenergic receptor	0	0	0	1
Alpha-2A adrenergic receptor	0	1	0	1
Nischarin	0	1	0	1
Chain A, CHIMERA OF IG KAPPA CHAIN: HUMAN CONSTANT REGION AND MOUSE VARIABLE REGION	0	0	1	1
Chain B, CHIMERA OF IG GAMMA-1 CHAIN: HUMAN CONSTANT REGION AND MOUSE VARIABLE REGION	0	0	1	1
Chain H, Fab M82G2, Heavy chain	0	0	1	1
Chain L, Fab M82G2, Light chain	0	0	1	1
Chain H, Fab M82g2, Heavy Chain	0	0	1	1
Chain L, Fab M82g2, Light Chain	0	0	1	1
Amyloid-beta precursor protein	1	5	0	6
Fatty acid-binding protein, heart	0	3	0	3
Muscarinic acetylcholine receptor M2	0	1	0	1
Liver carboxylesterase 1	0	2	0	3
Lysosomal Pro-X carboxypeptidase	0	2	0	2
Leukotriene B4 receptor 1	0	1	0	1
Leukotriene B4 receptor 2	0	1	0	1
nuclear receptor subfamily 0 group B member 1	0	3	0	3
steroidogenic factor 1	0	3	0	3
relaxin receptor 1 isoform 1	4	0	0	4
relaxin receptor 2 isoform 1	3	0	0	3
Nuclear receptor subfamily 1 group I member 2	0	0	4	4
Adenylate cyclase type 2	0	0	1	1
Adenylate cyclase type 8	0	0	1	1
Relaxin receptor 1	0	0	1	1
Nuclear receptor subfamily 1 group I member 2	0	0	2	2
Sex hormone-binding globulin	0	0	2	2
Corticosteroid-binding globulin	0	2	0	2
Mineralocorticoid receptor	0	0	1	1
C-8 sterol isomerase	0	3	0	3
Solute carrier organic anion transporter family member 1A1	0	1	0	1
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase	0	4	1	5
Receptor-type tyrosine-protein kinase FLT3	0	3	2	5
Sodium- and chloride-dependent creatine transporter 1	0	1	0	1
tyrosine-protein kinase Yes	1	0	0	1
Bone morphogenetic protein receptor type-1B	0	0	2	2
Membrane-associated progesterone receptor component 1	0	0	1	1
Serine/threonine-protein kinase PLK4	0	0	2	2
ATP-dependent RNA helicase DDX3X	0	0	2	2
Pyridoxal kinase	0	0	2	2
Citron Rho-interacting kinase	0	0	2	2
Aurora kinase A	0	0	2	2
Cyclin-G-associated kinase	0	0	2	2
Ephrin type-B receptor 6	0	0	2	2
Peroxisomal acyl-coenzyme A oxidase 3	0	0	2	2
Death-associated protein kinase 3	0	1	0	1
Receptor-interacting serine/threonine-protein kinase 2	0	0	2	2
Dynamin-like 120 kDa protein, mitochondrial	0	0	2	2
Rho-associated protein kinase 2	0	0	2	2
Serine/threonine-protein kinase ULK1	0	0	2	2
Serine/threonine-protein kinase/endoribonuclease IRE1	0	0	2	2
Ribosomal protein S6 kinase alpha-5	0	0	2	2
U5 small nuclear ribonucleoprotein 200 kDa helicase	0	0	2	2
Ribosomal protein S6 kinase alpha-4	0	0	2	2
Serine/threonine-protein kinase 16	0	0	2	2
Cyclin-dependent kinase-like 5	0	0	2	2
Serine/threonine-protein kinase 10	0	0	2	2
Serine/threonine-protein kinase D3	0	1	2	3
G2/mitotic-specific cyclin-B2	0	2	0	2
Structural maintenance of chromosomes protein 2	0	0	2	2
Mitogen-activated protein kinase kinase kinase 6	0	0	2	2
Mitogen-activated protein kinase kinase kinase kinase 4	0	0	2	2
Serine/threonine-protein kinase LATS1	0	0	2	2
Serine/threonine-protein kinase PAK 4	0	1	2	3
Tyrosine-protein kinase ABL1	0	2	3	5
ADP/ATP translocase 2	0	0	2	2
Tyrosine-protein kinase Lck	0	2	2	5
Tyrosine-protein kinase Fyn	0	2	2	4
Glycogen phosphorylase, liver form	0	0	2	2
Tyrosine-protein kinase Fes/Fps	0	0	2	2
Adenine phosphoribosyltransferase	0	0	2	2
Tyrosine-protein kinase Yes	0	0	2	2
Tyrosine-protein kinase Lyn	0	0	2	2
Proto-oncogene tyrosine-protein kinase receptor Ret	0	0	2	2
Insulin-like growth factor 1 receptor	0	0	2	2
Signal recognition particle receptor subunit alpha	0	0	2	2
Cytochrome c1, heme protein, mitochondrial	0	0	2	2
Hepatocyte growth factor receptor	0	2	2	4
Tyrosine-protein kinase HCK	0	0	2	2
Serine/threonine-protein kinase A-Raf	0	0	2	2
Glycogen phosphorylase, brain form	0	0	2	2
Breakpoint cluster region protein	0	0	2	2
ADP/ATP translocase 3	0	0	2	2
Proto-oncogene tyrosine-protein kinase Src	0	0	2	3
cAMP-dependent protein kinase type II-alpha regulatory subunit	0	0	2	2
G2/mitotic-specific cyclin-B1	0	2	0	2
Serine/threonine-protein kinase B-raf	0	1	2	3
Phosphorylase b kinase gamma catalytic chain, liver/testis isoform	0	0	2	2
Tyrosine-protein kinase Fer	0	0	2	2
cAMP-dependent protein kinase catalytic subunit alpha	0	0	2	2
General transcription and DNA repair factor IIH helicase subunit XPD	0	0	2	2
Ras-related protein Rab-6A	0	0	2	2
Multifunctional protein ADE2	0	0	2	2
cAMP-dependent protein kinase catalytic subunit gamma	0	0	1	1
cAMP-dependent protein kinase catalytic subunit beta	0	0	2	2
Ferrochelatase, mitochondrial	0	0	2	2
Ribosomal protein S6 kinase beta-1	0	2	2	4
Tyrosine-protein kinase JAK1	0	0	2	2
G1/S-specific cyclin-E1	0	1	0	1
Beta-adrenergic receptor kinase 1	0	0	2	2
Probable ATP-dependent RNA helicase DDX6	0	0	2	2
Mitogen-activated protein kinase 3	0	2	2	4
MAP/microtubule affinity-regulating kinase 3	0	0	2	2
Mitogen-activated protein kinase 1	0	2	2	4
Ephrin type-A receptor 2	0	0	2	2
Ephrin type-B receptor 2	0	0	2	2
Non-receptor tyrosine-protein kinase TYK2	0	0	2	2
Wee1-like protein kinase	0	0	2	2
Heme oxygenase 2	0	0	2	2
S-adenosylmethionine synthase isoform type-2	0	0	2	2
DnaJ homolog subfamily A member 1	0	0	2	2
RAC-alpha serine/threonine-protein kinase	0	1	2	3
RAC-beta serine/threonine-protein kinase	0	0	2	2
Dual specificity protein kinase TTK	0	0	2	2
DNA replication licensing factor MCM4	0	0	2	2
Dual specificity mitogen-activated protein kinase kinase 2	0	2	2	4
Bone morphogenetic protein receptor type-1A	0	0	2	2
Activin receptor type-1B	0	0	2	2
TGF-beta receptor type-1	0	0	2	2
TGF-beta receptor type-2	0	0	2	2
Electron transfer flavoprotein subunit beta	0	0	2	2
Tyrosine-protein kinase CSK	0	0	2	2
Glycine--tRNA ligase	0	0	2	2
Protein kinase C iota type	0	1	2	3
Exosome RNA helicase MTR4	0	0	2	2
Tyrosine-protein kinase Tec	0	0	2	2
Tyrosine-protein kinase ABL2	0	0	2	2
Tyrosine-protein kinase FRK	0	0	2	2
Tyrosine-protein kinase SYK	0	0	2	2
Mitogen-activated protein kinase 8	0	0	2	2
Mitogen-activated protein kinase 9	0	0	2	2
Dual specificity mitogen-activated protein kinase kinase 3	0	0	2	2
Casein kinase I isoform alpha	0	1	2	3
Casein kinase I isoform delta	0	1	2	3
MAP kinase-activated protein kinase 2	0	0	2	2
Elongation factor Tu, mitochondrial	0	0	2	2
Cysteine--tRNA ligase, cytoplasmic	0	0	2	2
Casein kinase I isoform epsilon	0	1	2	3
Very long-chain specific acyl-CoA dehydrogenase, mitochondrial	0	0	2	2
Dual specificity protein kinase CLK1	0	1	2	3
Dual specificity protein kinase CLK2	0	1	1	2
Dual specificity protein kinase CLK3	0	1	2	3
Glycogen synthase kinase-3 alpha	0	3	2	5
Glycogen synthase kinase-3 beta	0	4	4	8
Cyclin-dependent kinase 7	0	0	2	2
Interleukin-1 receptor-associated kinase 1	0	0	2	2
Ribosomal protein S6 kinase alpha-3	0	0	2	2
Serine/threonine-protein kinase Nek2	0	0	2	2
Serine/threonine-protein kinase Nek3	0	0	2	2
Dual specificity mitogen-activated protein kinase kinase 6	0	0	2	2
Serine/threonine-protein kinase PLK1	0	0	2	2
LIM domain kinase 1	0	1	2	3
LIM domain kinase 2	0	1	2	3
Mitogen-activated protein kinase 10	0	0	2	2
Tyrosine--tRNA ligase, cytoplasmic	0	0	2	2
5'-AMP-activated protein kinase subunit gamma-1	0	0	2	3
Ephrin type-B receptor 3	0	0	2	2
Ephrin type-A receptor 5	0	0	2	2
Ephrin type-B receptor 4	0	0	2	2
Ephrin type-A receptor 4	0	0	2	2
Adenylate kinase 2, mitochondrial	0	0	2	2
Ras-related protein Rab-10	0	0	2	2
Actin-related protein 3	0	0	2	2
Actin-related protein 2	0	0	2	2
GTP-binding nuclear protein Ran	0	0	2	2
Casein kinase I isoform gamma-2	0	1	2	3
Cyclin-dependent kinase 3	0	0	1	1
Cyclin-dependent kinase 6	0	0	2	2
Cyclin-dependent kinase 16	0	0	2	2
Cyclin-dependent kinase 17	0	0	2	2
ATP-dependent 6-phosphofructokinase, platelet type	0	0	2	2
DNA topoisomerase 2-beta	0	1	3	10
Activin receptor type-1	0	0	2	2
Macrophage-stimulating protein receptor	0	0	2	2
Focal adhesion kinase 1	0	0	2	2
Protein kinase C delta type	0	1	2	3
Tyrosine-protein kinase BTK	0	0	2	2
Activated CDC42 kinase 1	0	0	2	2
Epithelial discoidin domain-containing receptor 1	0	0	2	2
Mitogen-activated protein kinase kinase kinase kinase 2	0	0	2	2
Serine/threonine-protein kinase 4	0	0	2	2
5'-AMP-activated protein kinase catalytic subunit alpha-1	0	0	2	3
Dual specificity mitogen-activated protein kinase kinase 5	0	0	2	2
Mitogen-activated protein kinase 7	0	0	2	2
Serine/threonine-protein kinase PAK 2	0	1	2	3
Serine/threonine-protein kinase 3	0	0	2	2
Mitogen-activated protein kinase kinase kinase 1	0	0	2	2
Integrin-linked protein kinase	0	0	2	2
Rho-associated protein kinase 1	0	0	2	2
Non-receptor tyrosine-protein kinase TNK1	0	0	2	2
Calcium/calmodulin-dependent protein kinase type II subunit gamma	0	0	2	2
Calcium/calmodulin-dependent protein kinase type II subunit delta	0	0	2	2
Activin receptor type-2B	0	0	2	2
Bone morphogenetic protein receptor type-2	0	0	2	2
Protein-tyrosine kinase 6	0	0	2	2
cGMP-dependent protein kinase 1	0	0	2	2
Cyclin-dependent kinase 13	0	0	2	2
Inhibitor of nuclear factor kappa-B kinase subunit epsilon	0	0	2	2
Protein-tyrosine kinase 2-beta	0	0	2	2
Maternal embryonic leucine zipper kinase	0	0	2	2
Structural maintenance of chromosomes protein 1A	0	0	2	2
Chromodomain-helicase-DNA-binding protein 4	0	0	2	2
Ephrin type-A receptor 7	0	0	1	1
Delta(24)-sterol reductase	0	0	2	2
Dual specificity testis-specific protein kinase 1	0	0	2	2
Myosin light chain kinase, smooth muscle	0	0	2	2
Mitogen-activated protein kinase 11	0	0	2	2
Serine/threonine-protein kinase STK11	0	0	2	2
Serine/threonine-protein kinase N1	0	0	2	2
Serine/threonine-protein kinase N2	0	0	2	2
Mitogen-activated protein kinase 14	0	3	2	5
Calcium/calmodulin-dependent protein kinase type IV	0	0	2	2
Mitogen-activated protein kinase kinase kinase 11	0	0	2	2
MAP kinase-activated protein kinase 3	0	0	1	1
Discoidin domain-containing receptor 2	0	1	2	3
AP2-associated protein kinase 1	0	0	2	2
Myosin light chain kinase 3	0	0	2	2
Putative heat shock protein HSP 90-beta 2	0	0	2	2
Rab-like protein 3	0	0	1	1
Serine/threonine-protein kinase MRCK alpha	0	0	2	2
Serine/threonine-protein kinase MRCK gamma	0	0	2	2
Acyl-CoA dehydrogenase family member 10	0	0	2	2
Serine/threonine-protein kinase N3	0	0	2	2
Serine/threonine-protein kinase ULK3	0	0	2	2
Uncharacterized protein FLJ45252	0	0	2	2
Serine/threonine-protein kinase/endoribonuclease IRE2	0	0	2	2
Serine/threonine-protein kinase MARK2	0	0	2	2
Serine/threonine-protein kinase TAO1	0	0	2	2
STE20-related kinase adapter protein alpha	0	0	2	2
Myosin-14	0	0	2	2
AarF domain-containing protein kinase 1	0	0	2	2
Mitogen-activated protein kinase kinase kinase kinase 3	0	0	2	2
MAP kinase-activated protein kinase 5	0	2	2	4
Misshapen-like kinase 1	0	0	2	2
Atypical kinase COQ8A, mitochondrial	0	0	2	2
Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma	0	0	2	2
Mitogen-activated protein kinase 15	0	0	2	2
Serine/threonine-protein kinase Nek9	0	0	2	2
Serine/threonine-protein kinase Nek7	0	0	1	1
G2/mitotic-specific cyclin-B3	0	2	0	2
Mitogen-activated protein kinase kinase kinase kinase 1	0	0	2	2
Serine/threonine-protein kinase Nek1	0	0	2	2
Calcium/calmodulin-dependent protein kinase kinase 2	0	0	2	2
EKC/KEOPS complex subunit TP53RK	0	0	2	2
Dual specificity testis-specific protein kinase 2	0	0	2	2
Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase	0	0	2	2
Mitogen-activated protein kinase kinase kinase 5	0	0	2	2
Mitogen-activated protein kinase kinase kinase 3	0	0	2	2
Eukaryotic translation initiation factor 2-alpha kinase 1	0	0	2	2
Serine/threonine-protein kinase D2	0	0	2	2
NUAK family SNF1-like kinase 2	0	0	1	1
RNA cytidine acetyltransferase	0	0	2	2
Serine/threonine-protein kinase SIK2	0	0	2	2
STE20-like serine/threonine-protein kinase	0	0	2	2
Serine/threonine-protein kinase TAO3	0	0	2	2
Homeodomain-interacting protein kinase 3	0	1	0	1
dCTP pyrophosphatase 1	0	0	2	2
Dual specificity protein kinase CLK4	0	1	2	3
Casein kinase I isoform gamma-1	0	1	2	3
Phenylalanine--tRNA ligase beta subunit	0	0	2	2
BMP-2-inducible protein kinase	0	0	2	2
Midasin	0	0	2	2
Interleukin-1 receptor-associated kinase 4	0	0	2	2
Mitogen-activated protein kinase kinase kinase 20	0	0	2	2
Cyclin-dependent kinase 12	0	0	2	2
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13	0	0	1	1
Serine/threonine-protein kinase pim-2	0	1	0	1
Serine/threonine-protein kinase 26	0	0	2	2
Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial	0	0	2	2
Serine/threonine-protein kinase NLK	0	0	2	2
5'-AMP-activated protein kinase subunit gamma-2	0	0	2	3
Serine/threonine-protein kinase TBK1	0	1	2	3
Septin-9	0	0	2	2
Ribosomal protein S6 kinase alpha-6	0	0	2	2
TRAF2 and NCK-interacting protein kinase	0	0	2	2
Serine/threonine-protein kinase TAO2	0	0	2	2
Serine/threonine-protein kinase ICK	0	0	2	2
RAC-gamma serine/threonine-protein kinase	0	0	2	2
Serine/threonine-protein kinase 38-like	0	0	1	1
Serine/threonine-protein kinase SIK3	0	0	2	2
Mitogen-activated protein kinase kinase kinase 2	0	0	2	2
Thyroid hormone receptor-associated protein 3	0	0	2	2
Dual specificity tyrosine-phosphorylation-regulated kinase 1B	0	1	1	2
Mitogen-activated protein kinase kinase kinase kinase 5	0	0	2	2
Receptor-interacting serine/threonine-protein kinase 3	0	0	2	2
Serine/threonine-protein kinase MRCK beta	0	0	2	2
Interleukin-1 receptor-associated kinase 3	0	0	2	2
Serine/threonine-protein kinase 24	0	0	2	2
Casein kinase I isoform gamma-3	0	0	2	2
Mitogen-activated protein kinase kinase kinase 4	0	0	2	2
Multidrug resistance-associated protein 5	0	1	0	2
P53	1	0	0	1
RPL19A	0	0	1	1
heat shock protein HSP 90-alpha isoform 2	0	1	0	3
transactivating tegument protein VP16 [Human herpesvirus 1]	0	5	0	5
COUP transcription factor 2 isoform a	0	1	0	1
Polyunsaturated fatty acid 5-lipoxygenase	0	4	0	6
Eukaryotic initiation factor 4A-I	0	1	0	1
Peptidyl-prolyl cis-trans isomerase FKBP1A	0	4	1	5
Peptidyl-prolyl cis-trans isomerase FKBP3	0	1	0	1
Peptidyl-prolyl cis-trans isomerase FKBP4	0	1	0	1
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	0	4	1	5
Hypoxia-inducible factor 1-alpha	0	1	0	1
Endothelial PAS domain-containing protein 1	0	1	0	1
Peptidyl-prolyl cis-trans isomerase FKBP14	0	1	0	1
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 4	0	1	0	1
heat shock protein 90, putative	0	0	0	2
Deoxycytidine kinase	0	0	0	1
Glutathione S-transferase P	0	1	0	1
Alpha-tocopherol transfer protein	0	0	1	1
RAD51	0	1	0	1
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1	0	1	0	1
Growth factor receptor-bound protein 2	0	1	0	2
Pantothenate synthetase	0	1	0	1
Growth factor receptor-bound protein 2	0	1	0	1
Peptide-N(4)-(N-acetyl-beta-glucosaminyl)asparagine amidase	0	0	1	1
exodeoxyribonuclease V subunit RecD	0	2	0	2
exodeoxyribonuclease V subunit RecB	0	2	0	2
exodeoxyribonuclease V subunit RecC	0	2	0	2
Beta-glucuronidase	0	1	0	1
Beta-glucuronidase	0	1	0	1
Glucose-6-phosphate 1-dehydrogenase	0	4	0	4
G-protein coupled bile acid receptor 1	0	1	1	2
Glucose-6-phosphate 1-dehydrogenase	0	1	0	1
NPC1-like intracellular cholesterol transporter 1	0	0	1	1
Thymidine kinase 2	0	1	0	1
Probable deoxycytidylate deaminase	0	0	0	1
Cytidine deaminase	0	1	0	2
AAA family ATPase	0	0	0	1
AAA family ATPase	0	0	0	1
Sterol O-acyltransferase 1	0	2	0	2
Chain A, Dutpase	0	0	1	1
Chain A, Dutpase	0	0	1	1
Chain B, Dutpase	0	0	1	1
Chain A, Dutpase	0	0	1	1
Chain B, Dutpase	0	0	1	1
Amine oxidase [flavin-containing] B	0	4	0	4
Amine oxidase [flavin-containing] B	0	2	0	2
Trace amine-associated receptor 1	0	0	2	2
Trace amine-associated receptor 1	0	0	2	2
Trace amine-associated receptor 1	0	0	2	2
Gamma-aminobutyric acid	0	2	3	5
Alpha-1-acid glycoprotein 1	0	0	0	1
Albumin	0	3	3	7
Gamma-aminobutyric acid receptor subunit alpha-6	0	2	3	5
Gamma-aminobutyric acid receptor subunit gamma-2	0	2	3	5
Gamma-aminobutyric acid receptor subunit delta	0	2	3	5
Gamma-aminobutyric acid receptor subunit alpha-2	0	2	3	5
Gamma-aminobutyric acid receptor subunit alpha-3	0	2	3	5
Gamma-aminobutyric acid receptor subunit gamma-3	0	2	3	5
Gamma-aminobutyric acid receptor subunit beta-1	0	2	3	5
Gamma-aminobutyric acid receptor subunit alpha-1	0	3	3	6
Gamma-aminobutyric acid receptor subunit beta-3	0	2	3	5
Gamma-aminobutyric acid receptor subunit alpha-5	0	2	3	5
Gamma-aminobutyric acid receptor subunit pi	0	2	3	5
Sphingosine-1-phosphate lyase 1	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-4	0	2	3	5
Gamma-aminobutyric acid receptor subunit theta	0	2	3	5
Gamma-aminobutyric acid receptor subunit gamma-1	0	2	3	5
Estrogen receptor 1	0	0	1	1
TPA: protein transporter TIM10	0	1	0	1
Sterol O-acyltransferase 2	0	1	0	1
Sterol O-acyltransferase 1	0	2	0	2
Retinal dehydrogenase 1	0	1	0	1
Chain A, DigA16	0	0	1	1
Chain A, DigA16	0	0	1	1
Sodium/potassium-transporting ATPase subunit alpha-1	0	1	0	1
Sodium/potassium-transporting ATPase subunit beta-1	0	1	0	1
Sodium/potassium-transporting ATPase subunit alpha-2	0	1	0	1
Solute carrier organic anion transporter family member 4C1	0	2	0	2
Chain A, GLUTAMATE RECEPTOR SUBUNIT 2	0	3	0	3
Chain A, Glutamate Receptor Subunit 2	0	3	0	3
Chain B, Glutamate Receptor Subunit 2	0	3	0	3
Chain A, Glutamate receptor 2	0	1	0	1
Chain A, Glutamate receptor 2	0	1	0	1
Chain A, Glutamate receptor	0	1	0	1
Cereblon isoform 4	0	2	0	2
Insulin-like growth factor-binding protein 5	0	0	1	1
Protein cereblon	0	8	0	8
Chain A, Breast cancer type 1 susceptibility protein	2	0	0	2
acid sphingomyelinase	3	0	0	3
90-kda heat shock protein beta HSP90 beta, partial	0	1	0	1
DNA polymerase III, partial	2	0	0	2
isocitrate dehydrogenase 1, partial	2	0	0	2
LANA	0	0	0	1
eyes absent homolog 2 isoform a	2	0	0	2
DNA dC->dU-editing enzyme APOBEC-3F isoform a	4	0	0	4
kelch-like ECH-associated protein 1	0	0	0	2
Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta	0	1	0	1
3',5'-cyclic-AMP phosphodiesterase	0	2	0	2
Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha	0	1	0	1
Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma	0	1	0	1
Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit beta	0	1	0	1
Retinal cone rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma	0	1	0	1
Exopolyphosphatase PRUNE1	0	1	0	1
Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A	0	2	0	2
Phosphodiesterase	0	2	0	2
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A	0	2	0	2
glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase	0	1	0	1
LacZ protein (plasmid)	0	0	1	1
type-1 angiotensin II receptor	0	1	0	1
runt-related transcription factor 1 isoform AML1b	2	0	0	2
perilipin-5	0	1	0	1
glucose-6-phosphate 1-dehydrogenase isoform b	0	1	0	1
perilipin-1	0	1	0	1
histone deacetylase 9 isoform 3	6	0	0	6
core-binding factor subunit beta isoform 2	2	0	0	2
polypyrimidine tract-binding protein 1 isoform a	1	0	0	1
apelin receptor	0	1	0	1
1-acylglycerol-3-phosphate O-acyltransferase ABHD5 isoform a	0	1	0	1
bifunctional UDP-N-acetylglucosamine pyrophosphorylase/glucosamine-1-phosphate N-acetyltransferase	0	1	0	1
Carbamate kinase	0	1	0	1
Retinal dehydrogenase 1	0	1	0	1
Aldehyde dehydrogenase, mitochondrial	0	1	0	1
Fructose-1,6-bisphosphatase 1	0	1	0	1
C-X-C chemokine receptor type 2	0	2	0	2
Protein-lysine 6-oxidase	0	1	0	1
Lysine-specific demethylase 5A	0	1	0	1
C-C chemokine receptor type 2	0	2	0	2
C-C chemokine receptor type 4	0	2	0	2
C-C chemokine receptor type 5	0	2	0	2
Gasdermin-D	0	1	0	1
Lysyl oxidase homolog 3	0	1	0	1
Lysyl oxidase homolog 4	0	1	0	1
Monoglyceride lipase	0	1	0	1
Gasdermin-D	0	1	0	1
Histone-lysine N-methyltransferase EHMT1	0	3	0	3
Lysyl oxidase homolog 2	0	1	0	1
hypothetical protein CAALFM_CR05890CA	0	0	0	1
H3 histone acetyltransferase	0	0	0	1
large T antigen	0	2	0	2
Acetylcholinesterase	0	1	0	1
Amine oxidase [flavin-containing] A	0	1	0	1
Amine oxidase [flavin-containing] A	0	1	0	1
Acetylcholinesterase	0	2	0	2
Acetylcholinesterase	0	4	0	4
Acetylcholinesterase	0	1	0	1
Cholinesterase	0	2	0	2
Acetylcholine receptor subunit epsilon	0	1	0	1
Acyl-CoA:cholesterol acyltransferase	0	2	0	2
Carboxylic ester hydrolase	0	3	0	3
M18 aspartyl aminopeptidase	0	1	0	1
cathepsin L1	0	1	0	1
FAD-linked sulfhydryl oxidase ALR	0	0	0	1
D(3) dopamine receptor isoform e	1	0	0	1
Chain A, Protein (peroxisome Proliferator Activated Receptor (ppar-delta))	0	1	0	1
Retinoic acid receptor RXR-alpha	0	4	4	8
Oxoeicosanoid receptor 1	0	1	0	1
Chain A, Troponin C, slow skeletal and cardiac muscles	0	0	1	1
Chain A, Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	0	0	1	1
Chain A, POLYMERASE PA	0	1	0	1
Chain A, Polymerase Pa	0	1	0	1
Chain A, Polymerase Pa	0	1	0	1
Chain A, Polymerase Pa	0	1	0	1
Chain A, Polymerase Pa	0	1	0	1
Genome polyprotein	0	2	1	3
galactokinase	1	0	0	1
Prostaglandin E synthase	0	2	0	2
Telomerase reverse transcriptase	0	1	0	1
Polycomb protein EED	0	0	1	1
NAD kinase	0	2	1	3
Dihydrofolate reductase	0	8	0	10
Urokinase-type plasminogen activator	0	1	0	1
Tissue-type plasminogen activator	0	1	0	1
Transthyretin	0	1	1	3
Polymerase acidic protein	0	2	1	3
Plasminogen activator inhibitor 1	0	1	0	1
Heme oxygenase 1	0	1	0	1
Urokinase-type plasminogen activator	0	1	0	1
72 kDa type IV collagenase	0	2	0	2
Matrilysin	0	3	0	3
Enoyl-[acyl-carrier-protein] reductase [NADH] FabI	0	1	0	1
Alpha-amylase 1A	0	1	0	1
Apoptosis regulator Bcl-2	0	3	1	4
Microtubule-associated protein tau	0	1	0	1
Glucose-6-phosphate 1-dehydrogenase	0	1	0	1
Fatty acid synthase	0	1	0	1
CPG DNA methylase	0	1	0	1
Lethal factor	0	1	0	1
Phosphoglycerate mutase 1	0	1	0	1
Heme oxygenase 2	0	1	0	1
Dipeptidyl peptidase 4	0	4	0	4
Signal transducer and activator of transcription 1-alpha/beta	0	0	1	1
DNA repair protein RAD52 homolog	0	1	0	1
Fatty acid synthase	0	3	0	3
Matrix metalloproteinase-14	0	1	0	1
4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase FUT6	0	2	0	2
Squalene monooxygenase	0	1	0	1
6-phosphogluconate dehydrogenase, decarboxylating	0	2	0	2
BH3-interacting domain death agonist	0	1	0	1
Lactoperoxidase	0	0	0	1
Bcl-2-like protein 1	0	1	0	1
Induced myeloid leukemia cell differentiation protein Mcl-1	0	2	0	2
Histone acetyltransferase p300	0	1	0	1
Alpha-(1,3)-fucosyltransferase 7	0	2	0	2
CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 1	0	2	0	2
Bcl-2-related protein A1	0	1	0	1
3-oxoacyl-[acyl-carrier-protein] reductase	0	1	0	1
CREB-binding protein	2	1	0	3
Histone acetyltransferase KAT2B	0	1	0	1
Bcl-2-like protein 2	0	1	0	1
Bcl2-associated agonist of cell death	0	1	0	1
Histone acetyltransferase KAT5	0	1	0	1
Enoyl-acyl-carrier protein reductase	0	2	0	2
3-oxoacyl-acyl-carrier protein reductase	0	1	0	1
Beta-hydroxyacyl-ACP dehydratase precursor (Fatty acid synthesis protein)	0	1	0	1
Bcl-2-like protein 10	0	1	0	1
ATP-dependent translocase ABCB1	0	3	0	3
ATP-dependent translocase ABCB1	0	3	0	3
chaperonin-containing TCP-1 beta subunit homolog	3	0	0	3
Flavin reductase (NADPH)	0	0	1	1
LMP1 [Human herpesvirus 4]	0	0	0	2
nuclear receptor coactivator 1 isoform 1 [Homo sapiens]	0	3	0	3
nuclear receptor coactivator 3 isoform a	0	3	0	3
Regulatory protein E2	0	0	1	1
DNA topoisomerase 1	0	3	0	4
DNA topoisomerase 2-alpha	0	1	2	8
DNA topoisomerase 2	0	0	0	1
Serum paraoxonase/arylesterase 1	0	1	0	1
Caspase-3	0	1	0	1
DNA topoisomerase 2-alpha	0	0	0	1
Tubulin beta-2B chain	0	2	0	3
Integrase	0	1	0	1
Similar to alpha-tubulin isoform 1	0	2	0	3
Similar to alpha-tubulin isoform 1	0	2	0	3
NAD-dependent histone deacetylase SIR2	0	2	0	4
NAD-dependent protein deacetylase HST2	0	2	0	2
NAD-dependent protein deacetylase sirtuin-2	0	2	0	2
NAD-dependent protein deacetylase sirtuin-1	0	2	0	2
Histone deacetylase	0	3	0	3
Nuclear receptor corepressor 2	0	6	0	6
fatty acid synthase	0	1	0	1
interferon gamma precursor	0	0	0	2
streptokinase A precursor	0	0	3	3
Solute carrier family 15 member 1	0	2	0	2
Chain A, Dihydrofolate reductase	0	0	1	1
Dihydrofolate reductase	0	6	4	11
Aldo-keto reductase family 1 member B1	0	3	0	3
Folylpolyglutamate synthase, mitochondrial	0	1	0	4
Solute carrier organic anion transporter family member 1A3	0	1	0	3
Folylpolyglutamate synthase, mitochondrial	0	1	0	4
Multidrug resistance associated protein	0	1	0	3
Serine/threonine-protein kinase PAK 3	0	1	0	1
Serine/threonine-protein kinase PAK 1	0	1	0	1
Gamma-aminobutyric acid receptor subunit rho-3	0	0	1	3
Gamma-aminobutyric acid receptor subunit rho-1	0	0	2	4
Gamma-aminobutyric acid receptor subunit rho-2	0	0	1	3
Sterol O-acyltransferase 1	0	0	2	2
Sodium- and chloride-dependent GABA transporter 1	0	2	0	2
Sodium- and chloride-dependent taurine transporter	0	2	0	2
Sodium- and chloride-dependent GABA transporter 1	0	3	0	3
Sodium- and chloride-dependent GABA transporter 2	0	3	0	3
Sodium- and chloride-dependent GABA transporter 3	0	3	0	3
Sodium- and chloride-dependent betaine transporter	0	2	0	2
Sodium- and chloride-dependent GABA transporter 3	0	2	0	2
4-aminobutyrate aminotransferase, mitochondrial	0	0	0	1
4-aminobutyrate aminotransferase, mitochondrial	0	0	0	1
Platelet glycoprotein VI	0	1	2	4
Sodium- and chloride-dependent GABA transporter 2	0	2	0	2
Chain A, Slr1257 protein	0	0	1	1
Chain A, Glucosamine--fructose-6-phosphate aminotransferase [isomerizing]	0	1	0	1
Glutathione reductase, mitochondrial	0	4	0	4
Bifunctional aspartokinase/homoserine dehydrogenase 1	0	1	0	1
ATP-citrate synthase	0	1	0	1
Metabotropic glutamate receptor 2	0	0	1	1
Metabotropic glutamate receptor 3	0	0	1	1
Metabotropic glutamate receptor 4	0	1	1	2
Metabotropic glutamate receptor 6	0	0	1	1
Metabotropic glutamate receptor 7	0	0	1	1
Metabotropic glutamate receptor 8	0	0	1	1
Excitatory amino acid transporter 3	0	0	0	1
Glutamate racemase	0	0	0	1
Metabotropic glutamate receptor 8	0	1	1	2
Glutamate carboxypeptidase 2	0	1	0	1
Glutamate racemase	0	0	0	1
Prolyl 4-hydroxylase	0	2	0	2
Alpha-ketoglutarate-dependent dioxygenase FTO	0	2	0	2
Chain A, Glutamine Binding Protein	0	0	1	1
Asc-type amino acid transporter 1	0	1	0	1
Glycine receptor subunit alpha-1	0	0	3	3
Sodium- and chloride-dependent glycine transporter 1	0	1	0	1
Large neutral amino acids transporter small subunit 1	0	8	0	8
Serine racemase	0	1	0	1
Olfactory receptor 51E2	0	1	2	3
Sodium- and chloride-dependent glycine transporter 2	0	1	0	1
Hypoxanthine-guanine phosphoribosyltransferase	0	0	0	1
Ricin	0	1	0	1
2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase	0	0	1	1
Purine nucleoside phosphorylase	0	0	1	2
Shiga toxin subunit A	0	1	0	1
Chain A, ELONGATION FACTOR TU (EF-TU)	0	0	1	1
Chain A, Elongation Factor G	0	0	1	1
Chain A, ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 3	0	0	1	1
Chain A, Eukaryotic peptide chain release factor GTP-binding subunit	0	0	1	1
Chain A, ras-related C3 botulinum toxin substrate 1 isoform Rac1b	0	0	1	1
Chain A, ras-related C3 botulinum toxin substrate 1 isoform Rac1b	0	0	1	1
Chain A, interferon-inducible GTPase	0	0	1	1
Chain A, interferon-inducible GTPase	0	0	1	1
Chain A, Elongation factor 2	0	0	1	1
Chain A, Guanine nucleotide-binding protein G(i), alpha-1 subunit	0	0	1	1
2-dehydropantoate 2-reductase	0	0	2	2
Ras-related protein Rab-7a	0	0	2	2
4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase FUT5	0	1	0	1
P2Y purinoceptor 6	0	0	2	2
4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase 9	0	4	0	4
Chain A, Uracil Phosphoribosyltransferase	0	0	1	1
Chain B, Uracil Phosphoribosyltransferase	0	0	1	1
Chain C, Uracil Phosphoribosyltransferase	0	0	1	1
Chain A, HISTIDINE-BINDING PROTEIN	0	0	1	1
Plasma kallikrein	0	1	0	4
Histidine-binding periplasmic protein	0	0	1	1
Carbonic anhydrase	0	1	0	4
Glutaminyl-peptide cyclotransferase	0	1	0	1
Carbonic anhydrase	0	1	0	4
Carbonic anhydrase	0	1	0	4
Carbonic anhydrase	0	1	0	4
Carbonic anhydrase	0	1	0	4
N(G),N(G)-dimethylarginine dimethylaminohydrolase 1	0	2	0	3
ClpP	3	0	0	3
Solute carrier family 22 member 8	0	0	0	1
Uracil nucleotide/cysteinyl leukotriene receptor	0	1	0	1
Stromelysin-1	0	1	2	3
Urease subunit alpha	0	2	0	2
Ribonucleoside-diphosphate reductase large subunit	0	1	0	1
Urease subunit beta	0	2	0	2
Snq2p	0	0	0	3
Voltage-dependent L-type calcium channel subunit alpha-1C	0	4	0	4
Sphingomyelin phosphodiesterase	0	1	0	1
Pleiotropic ABC efflux transporter of multiple drugs	0	3	0	6
5-hydroxytryptamine receptor 2C	0	2	0	2
D(2) dopamine receptor	0	2	0	2
Envelope glycoprotein	0	0	2	2
Ornithine decarboxylase	0	0	0	2
Retinoic acid receptor alpha	0	2	2	4
Retinoic acid receptor gamma	0	2	2	4
Retinoic acid receptor beta	0	2	2	4
Cellular retinoic acid-binding protein 2	0	0	2	2
Retinoic acid receptor RXR-alpha	0	2	2	4
Retinoic acid receptor RXR-beta	0	2	2	4
Retinoic acid receptor RXR-gamma	0	2	2	4
Cellular retinoic acid-binding protein 1	0	2	0	3
Cellular retinoic acid-binding protein 1	0	0	2	2
Chain A, Glutamate receptor 2	0	0	1	1
Chain A, Glutamate receptor 2	0	0	1	1
Chain C, Glutamate receptor 2	0	0	1	1
Synaptic vesicular amine transporter	0	5	1	6
Vesicular acetylcholine transporter	0	1	0	1
Tyrosinase	0	1	1	2
D-amino-acid oxidase	0	1	0	1
Tyrosinase	0	3	0	3
D-amino-acid oxidase	0	1	0	1
Uncharacterized protein YOR062C	0	1	0	1
Polyphenol oxidase 1	0	2	0	2
Tyrosinase	0	1	0	1
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform	0	3	0	3
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform	0	2	0	2
Chain A, AMINOPEPTIDASE	0	1	0	1
Chain A, AMINOPEPTIDASE	0	1	0	1
Chain A, Leucine Aminopeptidase	0	1	0	1
Alkaline phosphatase, tissue-nonspecific isozyme	0	1	0	1
Intestinal-type alkaline phosphatase	0	1	0	1
Phospholipase A-2-activating protein	0	1	0	1
Synaptic vesicle glycoprotein 2A	0	2	0	2
WRN	1	0	0	1
integrase, partial	0	1	0	1
lens epithelium-derived growth factor p75	0	1	0	1
hexokinase-4 isoform 1	1	0	0	1
glucokinase regulatory protein	1	0	0	1
SLC16A10 protein	0	0	0	2
Monocarboxylate transporter 10	0	0	0	2
Free fatty acid receptor 1	0	0	1	1
Sterol O-acyltransferase 1	0	1	0	1
Tyrosine-protein phosphatase non-receptor type 7	0	1	0	1
Aldo-keto reductase family 1 member C3	0	1	0	1
Dual specificity protein phosphatase 3	0	1	0	1
Peroxisome proliferator-activated receptor alpha	1	0	0	1
Free fatty acid receptor 4	0	0	1	1
inositol monophosphatase 1	1	0	0	1
Neprilysin	0	1	0	1
Angiotensin-converting enzyme	0	1	0	1
Atrial natriuretic peptide receptor 3	0	1	0	1
Thromboxane A2 receptor	0	1	1	3
Type-1A angiotensin II receptor	0	2	1	3
Type-1B angiotensin II receptor	0	2	0	2
Type-1 angiotensin II receptor	0	3	2	7
Type-1 angiotensin II receptor	0	1	1	2
Type-2 angiotensin II receptor	0	2	0	2
Type-2 angiotensin II receptor	0	1	0	1
Squalene synthase	0	1	0	1
Type-1 angiotensin II receptor	0	1	1	2
Chain A, Antigen Cd11a (p180)	0	1	0	1
bcl-2-related protein A1	0	1	0	1
Integrin beta-2	0	1	0	1
Intercellular adhesion molecule 1	0	1	0	1
Insulin receptor	0	2	0	2
Integrin alpha-L	0	1	1	2
Substance-K receptor	0	4	0	4
Chain A, Ribulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase, chloroplast	0	1	0	1
Chain A, Ribulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase, chloroplast	0	1	0	1
Potassium voltage-gated channel subfamily KQT member 1	0	2	0	2
Cysteinyl leukotriene receptor 1	0	1	0	1
Cytochrome P450 1A2	0	1	0	1
Mu-type opioid receptor	0	5	0	5
Nociceptin receptor	0	1	0	1
Melatonin receptor type 1C	0	0	1	1
Melatonin receptor type 1A	0	1	1	2
Melatonin receptor type 1C	0	1	1	2
Melatonin receptor type 1B	0	1	1	2
Nuclear factor erythroid 2-related factor 2	0	1	2	5
Mas-related G-protein coupled receptor member X2	0	0	1	1
Aldehyde oxidase 1	0	1	0	1
Synaptic vesicular amine transporter	0	4	1	5
Chain A, Methionyl-tRNA synthetase	0	0	1	1
Chain A, Methionyl-tRNA synthetase	0	0	1	1
Chain A, Aminopeptidase	0	1	0	1
Chain A, Methionine aminopeptidase	0	1	0	1
S-ribosylhomocysteine lyase	0	1	0	1
Adenylate cyclase type 5	0	0	0	1
S-adenosylmethionine synthase isoform type-1	0	0	0	1
S-adenosylmethionine synthase isoform type-2	0	0	0	1
Chain B, DIHYDROFOLATE REDUCTASE	0	0	1	1
Chain B, DIHYDROFOLATE REDUCTASE	0	0	1	1
Chain B, DIHYDROFOLATE REDUCTASE	0	0	1	1
Thymidylate synthase	0	1	0	1
Toll-like receptor 4	0	1	0	1
ATP-binding cassette sub-family C member 3	0	1	0	2
Dihydrofolate reductase	0	3	0	4
Dihydrofolate reductase	0	4	0	4
Dihydrofolate reductase	0	3	0	3
Dihydrofolate reductase	0	1	0	1
Dihydrofolate reductase	0	4	0	5
Bifunctional dihydrofolate reductase-thymidylate synthase	0	3	0	3
High mobility group protein B1	0	0	2	2
Dihydrofolate reductase	0	3	0	3
Thymidylate synthase	0	2	0	2
Bifunctional dihydrofolate reductase-thymidylate synthase	0	5	0	5
Folate receptor beta	0	1	0	1
Cytochrome P450 11B1, mitochondrial	0	1	0	1
Folate receptor alpha	0	1	0	1
Dihydrofolate reductase	0	6	0	7
Histidine decarboxylase	0	1	0	1
Trifunctional purine biosynthetic protein adenosine-3	0	1	0	1
Bifunctional purine biosynthesis protein ATIC	0	2	0	2
Multidrug resistance-associated protein 1	0	1	0	2
Delta-type opioid receptor	0	5	0	6
Kappa-type opioid receptor	0	1	0	1
Reduced folate transporter	0	2	0	2
Dihydrofolate reductase	0	2	0	2
Pteridine reductase 1	0	4	0	4
Bifunctional dihydrofolate reductase-thymidylate synthase	0	3	0	4
Bifunctional dihydrofolate reductase-thymidylate synthase	0	1	0	1
Solute carrier family 22 member 6	0	1	0	2
Trifunctional purine biosynthetic protein adenosine-3	0	1	0	1
Dihydrofolate reductase	0	3	0	3
Solute carrier family 22 member 8	0	1	0	2
Dihydrofolate reductase	0	4	0	5
ATP-binding cassette sub-family C member 11	0	0	0	1
Proton-coupled folate transporter	0	1	0	1
Solute carrier family 22 member 11	0	0	0	1
Protein-arginine deiminase type-4	0	4	0	4
Chain A, Histamine N-methyltransferase	0	1	0	1
Chain A, Histamine N-methyltransferase	0	1	0	1
Chain A, Histamine N-methyltransferase	0	1	0	1
Chain A, Histamine N-methyltransferase	0	1	0	1
Histamine N-methyltransferase	0	1	0	2
Beta-2 adrenergic receptor	0	4	2	6
Beta-1 adrenergic receptor	0	6	2	8
Beta-3 adrenergic receptor	0	4	2	6
Beta-1 adrenergic receptor	0	4	2	7
Beta-1 adrenergic receptor	0	2	0	2
Multidrug transporter MdfA	0	1	0	1
Matrix metalloproteinase-9	0	1	0	1
Indoleamine 2,3-dioxygenase 1	0	1	0	1
vasopressin V1b receptor	2	0	0	2
Cytochrome P450 2C8	0	4	0	4
Thyroid hormone receptor beta	0	1	0	1
Adenosine receptor A1	0	2	0	2
Adenylate cyclase type 5	0	1	0	1
Adenosine receptor A1	0	2	1	3
Adenosine receptor A1	0	1	0	1
Adenosine receptor A2a	0	1	0	1
Adenosine receptor A3	0	1	0	1
Neurotensin receptor type 1	0	0	1	1
Neurotensin receptor type 2	0	1	1	3
Myelin basic protein	0	0	1	1
Neurotensin receptor type 1	0	1	1	2
Neurotensin receptor type 1	0	2	2	5
Neurotensin receptor type 2	0	2	1	3
Sortilin	0	1	0	1
Chain A, NAD-dependent deacetylase	0	1	0	1
Poly [ADP-ribose] polymerase 2	0	1	0	1
Poly [ADP-ribose] polymerase 1	0	1	0	1
NAD(+) hydrolase SARM1	0	1	0	1
NAD-dependent protein deacetylase sirtuin-6	0	2	1	3
NAD-dependent protein deacetylase sirtuin-3, mitochondrial	0	1	0	1
NAD-dependent protein deacetylase	0	1	0	1
Sodium- and chloride-dependent betaine transporter	0	1	0	1
Carbonic anhydrase 2	0	2	0	2
Sodium/iodide cotransporter	0	1	0	1
Chain A, Glutathione-requiring prostaglandin D synthase	0	1	0	1
Tubulin alpha-1A chain	0	2	0	2
Tubulin beta chain	0	2	0	2
Tubulin beta-4A chain	0	1	1	2
Tubulin beta chain	0	1	1	2
Tubulin alpha-3C chain	0	1	1	2
Tubulin alpha-1B chain	0	1	1	2
Tubulin alpha-4A chain	0	1	1	2
Tubulin beta-4B chain	0	1	1	2
Tubulin beta-3 chain	0	1	1	2
Tubulin beta-2A chain	0	1	1	2
Tubulin beta-8 chain	0	1	1	2
Tubulin alpha-3E chain	0	1	1	2
Tubulin alpha-1A chain	0	1	1	2
Tubulin alpha-1C chain	0	1	1	2
Tubulin beta-6 chain	0	1	1	2
Tubulin beta-2B chain	0	1	1	2
Tubulin beta-1 chain	0	1	1	2
Ras-related C3 botulinum toxin substrate 1	0	1	0	1
Ras-related C3 botulinum toxin substrate 1	0	1	0	1
Protein Mdm4	0	2	0	2
E3 ubiquitin-protein ligase Mdm2	0	1	0	1
E3 ubiquitin-protein ligase Mdm2	0	1	0	1
E3 ubiquitin-protein ligase Mdm2	1	3	1	5
Peptidyl-prolyl cis-trans isomerase D	0	1	0	1
Mu-type opioid receptor	0	0	1	1
N(G),N(G)-dimethylarginine dimethylaminohydrolase 1	0	0	0	1
Proteinase-activated receptor 1	0	1	0	1
Nitric oxide synthase, endothelial	0	2	0	2
Collagenase 3	0	1	0	1
Nitric oxide synthase, brain	0	1	0	1
Chain A, ARGINASE 1	0	1	0	1
Chain A, Arginase 1	0	1	0	1
Chain A, ARGINASE 1	0	1	0	1
Chain A, L-ARGININE\\:GLYCINE AMIDINOTRANSFERASE	0	1	0	1
Vasopressin V2 receptor	0	1	1	2
Oxytocin receptor	0	2	2	4
Vasopressin V1a receptor	0	1	0	1
Vasopressin V1a receptor	0	3	2	5
Vasopressin V1b receptor	0	1	1	2
Vasopressin V1b receptor	0	1	0	1
Oxytocin receptor	0	1	0	1
Oxytocin receptor	0	0	1	1
Vasopressin V2 receptor	0	1	0	1
Photosystem I iron-sulfur center	0	0	0	1
Cystathionine gamma-lyase	0	2	0	2
Succinyl-diaminopimelate desuccinylase	0	1	0	1
guanine nucleotide-binding protein subunit alpha-15	0	1	1	2
trace amine-associated receptor 1	0	1	1	2
Chain A, Immunoglobulin	0	0	1	1
Chain B, Immunoglobulin	0	0	1	1
Kappa-type opioid receptor	0	0	0	1
Mu-type opioid receptor	0	0	0	1
Muscarinic acetylcholine receptor M5	0	0	1	2
Tyrosine-protein phosphatase non-receptor type 11	0	0	0	1
Taste receptor type 2 member 31	0	0	1	1
Taste receptor type 2 member 60	0	0	1	1
Sodium/potassium/calcium exchanger 4	0	1	1	2
Taste receptor type 2 member 14	0	0	1	2
Taste receptor type 2 member 13	0	0	1	1
Taste receptor type 2 member 9	0	0	1	1
Taste receptor type 2 member 4	0	0	1	1
Sodium/potassium/calcium exchanger 2	0	1	1	2
Chain A, Ferritin light chain	0	0	1	1
Chain A, Ferritin light chain	0	0	1	1
Chain A, Ferritin light chain	0	0	1	1
Chain A, Ferritin light chain	0	0	1	1
Chain A, Ferritin light chain	0	0	1	1
Chain A, Ferritin light chain	0	0	1	1
Chain A, Ferritin light chain	0	0	1	1
UDP-glucuronosyltransferase 1A9	0	0	0	2
UDP-glucuronosyltransferase 1A8	0	0	0	1
Beta-2 adrenergic receptor	0	2	0	3
Voltage-dependent L-type calcium channel subunit alpha-1C	0	2	0	2
Endothelin-1 receptor	0	1	1	2
Beta-3 adrenergic receptor	0	2	0	2
Neuromedin-K receptor	0	0	1	1
Cholecystokinin receptor type A	0	1	1	2
Beta-2 adrenergic receptor	0	1	0	1
Sodium/bile acid cotransporter	0	1	0	1
Nuclear receptor subfamily 2 group E member 1	0	0	2	2
dual specificity protein phosphatase 3	0	1	0	1
low molecular weight phosphotyrosine protein phosphatase isoform c	0	1	0	1
tyrosine-protein phosphatase non-receptor type 22 isoform 1	0	1	0	1
Bifunctional dihydrofolate reductase-thymidylate synthase	0	1	0	1
Estrogen receptor	0	0	2	3
Beta-hexosaminidase subunit alpha	0	1	0	2
Beta-hexosaminidase subunit beta	0	1	0	1
Substance-K receptor	0	1	0	1
Dihydrofolate reductase	0	2	0	2
Low molecular weight phosphotyrosine protein phosphatase	0	1	0	1
Bifunctional dihydrofolate reductase-thymidylate synthase	0	2	0	2
Trace amine-associated receptor 5	0	0	2	2
Estrogen receptor beta	0	0	2	3
Bifunctional dihydrofolate reductase-thymidylate synthase	0	2	0	2
Multidrug and toxin extrusion protein 1	0	1	0	1
Monocarboxylate transporter 2	0	0	0	1
Monocarboxylate transporter 1	0	0	0	1
C-terminal-binding protein 2	0	1	0	1
Monocarboxylate transporter 2	0	1	0	1
Quinolone resistance protein NorA	0	1	0	2
Chromaffin granule amine transporter	0	1	0	1
Synaptic vesicular amine transporter	0	2	0	2
5-hydroxytryptamine receptor 2A	0	1	0	1
5-hydroxytryptamine receptor 2B	0	1	0	1
Transporter	0	1	0	1
5-hydroxytryptamine receptor 1A	0	1	0	1
Chain A, cAMP-specific phosphodiesterase PDE4D2	0	1	0	1
Chain A, cAMP-specific phosphodiesterase PDE4D2	0	1	0	1
Chain A, cAMP-specific 3',5'-cyclic phosphodiesterase 4B	0	1	0	1
Chain A, cAMP-specific 3',5'-cyclic phosphodiesterase 4D	0	1	0	1
Chain A, cAMP-specific 3',5'-cyclic phosphodiesterase 4D	0	1	0	1
Chain A, cAMP-specific 3',5'-cyclic phosphodiesterase 4D	0	1	0	1
Chain A, cAMP-specific 3',5'-cyclic phosphodiesterase 4D	0	1	0	1
Chain A, cAMP-specific 3',5'-cyclic phosphodiesterase 4D	0	1	0	1
Chain A, cAMP-specific 3',5'-cyclic phosphodiesterase 4D	0	1	0	1
Retina-specific copper amine oxidase	0	1	0	1
High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B	0	1	0	1
Tumor necrosis factor	0	1	0	1
Bifunctional epoxide hydrolase 2	0	2	0	2
cGMP-dependent 3',5'-cyclic phosphodiesterase	0	1	0	1
cGMP-specific 3',5'-cyclic phosphodiesterase	0	1	0	1
Endothelin-1 receptor	0	1	0	1
Phosphodiesterase	0	1	0	1
Chain A, ADENINE-N6-DNA-METHYLTRANSFERASE TAQI	0	0	1	1
Chain A, Adenine-n6-dna-methyltransferase Taqi	0	0	1	1
Chain A, Histamine N-Methyltransferase	0	1	0	1
Chain A, Histamine N-Methyltransferase	0	1	0	1
Chain A, Modification Methylase Rsri	0	0	1	1
Chain A, Modification Methylase Rsri	0	0	1	1
Chain A, Ermc' Methyltransferase	0	1	0	1
Chain A, Ermc' Rrna Methyltransferase	0	1	0	1
Chain A, Uroporphyrin-III C-methyltransferase	0	1	0	1
Chain B, ADENINE-N6-DNA-METHYLTRANSFERASE TAQI	0	0	1	1
Chain A, Ribulose-1,5 bisphosphate carboxylase/oxygenase	0	0	1	1
Chain A, Ribulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase	0	0	1	1
Chain A, Ribulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase	0	0	1	1
Chain A, Ribulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase	0	0	1	1
tRNA (cytosine(38)-C(5))-methyltransferase	0	1	1	2
Protein arginine N-methyltransferase 5	0	1	0	1
Histone-lysine N-methyltransferase SUV39H1	0	2	0	2
Adenosylhomocysteinase	0	0	0	1
Protein arginine N-methyltransferase 3	0	1	0	1
Indolethylamine N-methyltransferase	0	1	0	1
Histone-lysine N-methyltransferase NSD2	0	1	0	1
Adenosylhomocysteinase	0	0	0	1
Phenylethanolamine N-methyltransferase	0	1	0	1
rRNA adenine N-6-methyltransferase	0	1	0	1
Catechol O-methyltransferase	0	0	0	1
Nicotinamide N-methyltransferase	0	1	0	1
WD repeat-containing protein 5	0	1	0	1
tRNA (guanine-N(1)-)-methyltransferase	0	0	1	1
Histone-lysine N-methyltransferase 2A	0	1	0	1
Histone-lysine N-methyltransferase SETDB1	0	1	0	1
Retinoblastoma-binding protein 5	0	1	0	1
Histone-lysine N-methyltransferase EZH2	0	1	0	1
tRNA (guanine-N(1)-)-methyltransferase	0	0	1	1
N6-adenosine-methyltransferase catalytic subunit	0	1	0	1
Histone-arginine methyltransferase CARM1	0	1	0	1
Histone-lysine N-methyltransferase KMT5C	0	1	0	1
Histone-lysine N-methyltransferase SETD7	0	1	0	1
Histone-lysine N-methyltransferase EZH1	0	1	0	1
Protein arginine N-methyltransferase 1	0	2	0	2
Methylosome protein 50	0	1	0	1
Protein dpy-30 homolog	0	1	0	1
Histamine N-methyltransferase	0	0	0	1
Histone-lysine N-methyltransferase SUV39H2	0	1	0	1
tRNA (guanine-N(1)-)-methyltransferase	0	0	1	1
N-lysine methyltransferase SMYD2	0	1	0	1
Protein arginine N-methyltransferase 7	0	1	0	1
DNA (cytosine-5)-methyltransferase 3B	0	1	0	1
Set1/Ash2 histone methyltransferase complex subunit ASH2	0	1	0	1
DNA (cytosine-5)-methyltransferase 3A	0	1	0	1
Non-structural protein 1	0	1	0	1
Estrogen receptor beta	0	0	0	1
Inhibitor of nuclear factor kappa-B kinase subunit beta	0	0	0	1
5'-AMP-activated protein kinase subunit beta-2	0	0	0	1
Tyrosine-protein phosphatase YopH	0	1	0	1
Tyrosine-protein phosphatase non-receptor type 1	0	1	0	3
Estrogen receptor	0	0	0	1
5'-AMP-activated protein kinase catalytic subunit alpha-2	0	0	0	1
Xanthine dehydrogenase/oxidase	0	1	0	1
Carbonic anhydrase	0	1	0	1
Solute carrier family 22 member 7	0	0	0	1
Ubiquitin-like domain-containing CTD phosphatase 1	0	1	0	1
5'-AMP-activated protein kinase subunit gamma-3	0	0	0	1
5'-AMP-activated protein kinase subunit beta-1	0	0	0	1
glycogen synthase kinase-3 alpha	0	0	0	1
Pyruvate kinase PKM	0	0	1	1
Transcriptional activator protein LuxR	0	2	0	2
3-oxo-5-alpha-steroid 4-dehydrogenase 2	0	1	0	1
Melanocortin receptor 5	0	4	0	4
photoreceptor-specific nuclear receptor	0	1	0	1
Cell division cycle 7-related protein kinase	0	0	1	1
Mitotic checkpoint serine/threonine-protein kinase BUB1	0	0	1	1
Tyrosine-protein kinase JAK2	0	1	1	2
Eukaryotic translation initiation factor 5B	0	0	1	1
Eukaryotic translation initiation factor 4E	0	0	1	1
Tyrosine-protein kinase Fgr	0	0	1	1
Ephrin type-A receptor 1	0	0	1	1
Peptidyl-prolyl cis-trans isomerase FKBP1A	0	1	0	1
UMP-CMP kinase	0	0	1	1
Phosphatidylethanolamine-binding protein 1	0	0	1	1
Myosin-10	0	0	1	1
Serine/threonine-protein kinase receptor R3	0	0	1	1
G protein-coupled receptor kinase 6	0	0	1	1
Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha	0	0	1	1
Choline-phosphate cytidylyltransferase A	0	0	1	1
Ras-related protein Rab-27A	0	0	1	1
Peptidyl-prolyl cis-trans isomerase FKBP1B	0	0	1	1
Protein kinase C theta type	0	1	1	2
Protein kinase C zeta type	0	1	1	2
Cyclin-dependent kinase 18	0	0	1	1
Tyrosine-protein kinase Mer	0	0	1	1
Peptidyl-prolyl cis-trans isomerase FKBP5	0	1	0	1
Peroxisomal acyl-coenzyme A oxidase 1	0	0	1	1
Uncharacterized aarF domain-containing protein kinase 5	0	0	1	1
Programmed cell death protein 4	0	0	1	1
Acyl-CoA dehydrogenase family member 11	0	0	1	1
ATP-dependent RNA helicase DHX30	0	0	1	1
Regulatory-associated protein of mTOR	0	1	0	1
ATP-dependent RNA helicase DDX1	0	0	1	1
MAP/microtubule affinity-regulating kinase 4	0	0	1	1
Calcium/calmodulin-dependent protein kinase type 1G	0	0	1	1
PAS domain-containing serine/threonine-protein kinase	0	0	1	1
Target of rapamycin complex subunit LST8	0	1	0	1
Nucleolar GTP-binding protein 1	0	0	1	1
Serine/threonine-protein kinase mTOR	0	1	0	1
Isoleucine--tRNA ligase, mitochondrial	0	0	1	1
Obg-like ATPase 1	0	0	1	1
epidermal growth factor receptor isoform a precursor	0	1	0	1
Transcription factor AP-1	0	1	0	1
Dual specificity mitogen-activated protein kinase kinase 4	0	1	0	1
Carbonic anhydrase	0	2	0	2
Carbonic anhydrase	0	1	0	1
Orexin receptor type 1	0	0	0	1
Cathepsin B	0	1	0	1
Kappa-type opioid receptor	0	0	0	1
C-X-C chemokine receptor type 3	0	1	0	1
N-arachidonyl glycine receptor	0	1	0	1
GTPase HRas	0	1	0	1
Chain A, Ribosomal protein S6 kinase alpha-1	0	1	0	1
Chain X, Tyrosine-protein kinase Lyn	0	1	0	1
Chain A, Dual specificity protein kinase TTK	0	0	1	1
Chain A, Dual specificity protein kinase TTK	0	0	1	1
NAD(P)H dehydrogenase [quinone] 1	0	0	0	2
Transcription regulator protein BACH1	0	1	0	1
Transcription factor MafK	0	1	0	1
Macrophage migration inhibitory factor	0	1	0	1
NAD	0	0	0	1
Quinone oxidoreductase	0	0	0	3
Kelch-like ECH-associated protein 1	0	1	2	3
Nuclear factor erythroid 2-related factor 2	0	0	0	1
Kelch-like ECH-associated protein 1	0	0	0	1
Aldo-keto reductase family 1 member B10	0	1	0	1
Complement C5	0	0	1	1
Polyunsaturated fatty acid 5-lipoxygenase	0	1	0	1
Lactoylglutathione lyase	0	1	0	1
Chain A, CES1 protein	0	1	0	1
Lysosomal acid glucosylceramidase	0	0	1	1
Protein kinase C alpha type	0	2	0	2
Progesterone receptor	0	1	0	1
Protein kinase C delta type	0	2	0	2
Protein kinase C epsilon type	0	2	0	2
Protein kinase C zeta type	0	2	0	2
Steroid hormone receptor ERR1	0	1	0	1
Protein kinase C eta type	0	1	0	1
Substance-P receptor	0	2	0	2
B2 bradykinin receptor	0	2	0	2
Melanocortin receptor 4	0	2	0	2
Melanocortin receptor 3	0	2	0	2
Protein kinase C gamma type	0	2	0	2
Protein kinase C beta type	0	2	0	2
Phospholipase D1	0	1	0	1
Protein kinase C epsilon type	0	1	0	1
Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform	0	1	0	1
Platelet-activating factor acetylhydrolase	0	2	0	2
Serine/threonine-protein kinase D1	0	1	0	1
Protein kinase C eta type	0	2	0	2
Emopamil-binding protein-like	0	2	0	2
7-dehydrocholesterol reductase	0	1	1	2
Protein kinase C theta type	0	2	0	2
Potassium voltage-gated channel subfamily A member 1	0	1	0	1
Solute carrier family 22 member 4	0	0	0	1
Solute carrier family 22 member 4	0	1	0	1
Solute carrier family 22 member 3	0	0	0	1
Solute carrier family 22 member 4	0	0	0	1
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform	0	1	0	1
Phosphatidylinositol 3-kinase regulatory subunit alpha	0	2	0	2
Thymidine kinase	0	2	0	3
Thymidine kinase	0	1	0	2
Thymidine phosphorylase	0	0	0	1
Thymidine kinase, cytosolic	0	0	0	2
Thymidine kinase	0	1	0	2
Thymidine kinase	0	0	0	1
Thymidine kinase	0	0	0	1
Chain A, ANAEROBIC RIBONUCLEOTIDE-TRIPHOSPHATE REDUCTASE LARGE CHAIN	0	0	1	1
Chain A, ANAEROBIC RIBONUCLEOTIDE-TRIPHOSPHATE REDUCTASE LARGE CHAIN	0	0	1	1
Chain A, Deoxynucleoside kinase	0	1	0	1
Chain A, Thymidylate Synthase	0	0	1	1
Thymidine phosphorylase	0	1	0	1
Chain X, Thyroid hormone receptor beta-1	0	0	1	1
Chain X, Thyroid hormone receptor beta-1	0	0	1	1
Solute carrier organic anion transporter family member 1A4	0	0	0	1
Solute carrier organic anion transporter family member 1A5	0	0	0	1
Thyroid hormone receptor alpha	0	0	1	1
Thyroid hormone receptor beta	0	0	1	1
Proliferating cell nuclear antigen	0	1	0	1
Malate dehydrogenase, mitochondrial	0	1	0	1
Solute carrier organic anion transporter family member 1A2	0	0	0	1
Monocarboxylate transporter 8	0	0	0	1
Bile acid receptor	0	1	0	1
Solute carrier organic anion transporter family member 1C1	0	0	0	1
Endolysin	0	0	1	1
Chain A, Carbonic anhydrase 1	0	1	0	1
Carbonic anhydrase	0	0	0	1
Carbonic anhydrase	0	1	0	1
Carbonic anhydrase	0	1	0	1
Carbonic anhydrase	0	1	0	1
Carbonic anhydrase	0	1	0	1
Prolyl endopeptidase	0	1	0	1
Carbonic anhydrase-related protein 11	0	0	0	1
Arachidonate 5-lipoxygenase-activating protein	0	1	0	1
Carbonic anhydrase 5A, mitochondrial	0	1	0	1
Carbonic anhydrase 2	0	1	0	1
Carbonic anhydrase	0	1	0	1
Carbonic anhydrase, alpha family	0	1	0	1
Carbonic anhydrase	0	1	0	1
Delta carbonic anhydrase	0	1	0	1
Chain A, Nuclear Receptor ROR-beta	0	1	0	1
Retinoic acid receptor alpha	0	2	2	7
Retinoic acid receptor beta	0	2	2	7
Retinoic acid receptor gamma	0	2	2	7
Retinoic acid receptor RXR-beta	0	2	2	4
Indoleamine 2,3-dioxygenase 1	0	1	0	1
Nuclear receptor ROR-alpha	0	1	0	1
Retinoic acid receptor RXR-gamma	0	2	2	4
Indoleamine 2,3-dioxygenase 2	0	1	0	1
Nuclear receptor ROR-beta	0	1	0	1
Chain A, HDLP (HISTONE DEACETYLASE-LIKE PROTEIN)	0	1	0	1
Chain B, HDLP (HISTONE DEACETYLASE-LIKE PROTEIN)	0	1	0	1
Chain A, Histone deacetylase 7a	0	1	0	1
Chain A, Histone deacetylase 7a	0	1	0	1
Histone deacetylase 8	0	2	0	2
Histone deacetylase	0	2	0	2
unnamed protein product	0	0	0	1
Histone deacetylase 1	0	4	0	4
Histone deacetylase 3	0	1	0	1
Leukotriene A-4 hydrolase	0	2	0	2
Vitamin D3 receptor	0	1	0	1
Histone deacetylase 2	0	1	0	1
Splicing factor 3B subunit 3	0	1	0	1
Histone deacetylase 1	0	2	0	2
Histone deacetylase	0	2	0	2
Histone deacetylase 4	0	1	0	1
Polyamine deacetylase HDAC10	0	1	0	1
Histone deacetylase 3	0	2	0	2
Histone deacetylase-like amidohydrolase	0	4	1	5
Histone deacetylase 7	0	1	0	1
Histone deacetylase 8	0	1	0	1
Histone deacetylase 11	0	1	0	1
HD2 type histone deacetylase HDA106	0	4	0	4
Histone deacetylase 9	0	1	0	1
Histone deacetylase 7	0	2	0	2
Histone deacetylase 6	0	2	0	2
Histone deacetylase 4	0	2	0	2
Histone deacetylase 6	0	2	0	2
Histone deacetylase 5	0	1	0	1
Histone deacetylase	0	2	0	2
Genome polyprotein	0	1	0	1
NADPH oxidase 1	0	1	0	1
DNA repair protein RAD52 homolog isoform a	0	0	0	1
Ubiquitin carboxyl-terminal hydrolase 1	0	1	0	1
Lysozyme C-1	0	1	0	1
Beta-glucuronidase	0	1	0	1
Calmodulin-1	0	0	1	1
Trypanothione reductase	0	2	0	2
Calcium-dependent protein kinase 4	0	1	0	1
WD repeat-containing protein 48	0	1	0	1
Chain A, Dihydrofolate Reductase	0	0	1	1
Chain A, Dihydrofolate reductase	0	1	0	1
Chain A, dihydrofolate reductase (DHFR)	0	1	0	1
Chain A, Dihydrofolate reductase	0	1	0	1
Chain A, Dihydrofolate reductase	0	1	0	1
Dihydrofolate reductase	0	1	0	2
Dihydrofolate reductase type 1	0	1	0	2
Dihydrofolate reductase	0	1	0	1
Dihydrofolate reductase	0	1	0	1
NH(3)-dependent NAD(+) synthetase	0	1	0	1
Dihydrofolate reductase type 1 from Tn4003	0	1	0	1
Dipeptidyl peptidase 4	0	1	0	1
Bifunctional dihydrofolate reductase-thymidylate synthase	0	1	0	1
Dihydrofolate reductase	0	1	0	1
Dihydrofolate reductase	0	1	0	1
Dihydrofolate reductase	0	1	0	1
Dihydrofolate reductase	0	1	0	1
Chain A, CHORISMATE MUTASE	0	1	0	1
Chain A, TYROSYL-tRNA SYNTHETASE	0	0	1	1
RAF proto-oncogene serine/threonine-protein kinase	0	1	0	1
Malate dehydrogenase	0	1	0	1
Potassium voltage-gated channel subfamily E member 1	0	1	0	1
Spindlin-1	0	1	0	1
Coagulation factor XIII A chain	0	1	0	1
Fatty-acid amide hydrolase 2	0	1	0	1
Chain A, Cytidine Deaminase	0	1	0	1
Uridine-cytidine kinase 1	0	0	0	1
P2Y purinoceptor 4	0	0	1	1
N-acetyllactosaminide alpha-1,3-galactosyltransferase	0	1	0	1
P2Y purinoceptor 2	0	1	1	2
P2Y purinoceptor 2	0	0	1	1
P2Y purinoceptor 2	0	0	1	1
P2Y purinoceptor 1	0	0	1	1
P2Y purinoceptor 4	0	0	1	1
RNA-directed RNA polymerase	0	0	0	1
P2Y purinoceptor 11	0	0	1	1
Chain A, Arginase 1	0	1	0	1
Cocaine esterase	0	1	0	1
Aldo-keto reductase family 1 member A1	0	1	0	1
Aldo-keto reductase family 1 member A1	0	1	0	1
Aldo-keto reductase family 1 member A1	0	1	0	1
Aldo-keto reductase family 1 member B7	0	1	0	1
Acetylcholine receptor subunit alpha	0	2	1	3
Acetylcholine receptor subunit gamma	0	2	1	3
Acetylcholine receptor subunit beta	0	2	1	3
Neuronal acetylcholine receptor subunit beta-2	0	2	1	3
Neuronal acetylcholine receptor subunit alpha-5	0	0	1	1
Neuronal acetylcholine receptor subunit beta-4	0	2	1	3
Neuronal acetylcholine receptor subunit alpha-3	0	2	1	3
Neuronal acetylcholine receptor subunit alpha-7	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-4	0	2	1	3
Acetylcholine receptor subunit delta	0	2	1	3
Chain A, Histone deacetylase-like amidohydrolase	0	1	0	1
Chain A, Histone deacetylase-like amidohydrolase	0	1	0	1
cystic fibrosis transmembrane conductance regulator ATP-binding cassette sub-family C member 7	0	0	0	1
Gli1	0	1	0	1
protein Wnt-3a precursor	0	1	0	1
Transient receptor potential cation channel subfamily V member 1	0	1	0	1
Lysine-specific histone demethylase 1A	0	1	0	1
Bromodomain-containing protein 4	0	1	0	1
Nuclear receptor corepressor 1	0	2	0	2
Protein Tat	0	0	1	1
Aminopeptidase N	0	1	0	1
Polyunsaturated fatty acid lipoxygenase ALOX15	0	0	0	1
Polyunsaturated fatty acid lipoxygenase ALOX12	0	0	0	1
Leukotriene A-4 hydrolase	0	1	0	1
Vascular endothelial growth factor receptor 2	0	1	0	1
Apoptosis regulator BAX	0	0	1	1
Renin	0	1	0	1
Histone deacetylase	0	1	0	1
Carboxypeptidase B2	0	1	0	1
REST corepressor 3	0	1	0	1
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Synonyms(1)

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Research

Studies (812)

Protein Targets (2,359)

Fragile X Syndrome

Synonyms(1)

Research Excerpts

Overview

Context

Actions

Treatment

Research

Studies (812)

Drugs Studied (418)

Protein Targets (2,359)