Bartholin-Patau Syndrome

A chromosome disorder associated with TRISOMY of all or part of CHROMOSOME 13. Clinical manifestations include CONGENITAL HEART DEFECTS (e.g., PATENT DUCTUS ARTERIOSUS), facial malformations (e.g., CLEFT LIP; CLEFT PALATE; COLOBOMA; MICROPHTHALMIA); HYPOTONIA, digit malformations (e.g., POLYDACTYLY or SYNDACTYLY), and SEIZURES and severe INTELLECTUAL DISABILITY associated with NERVOUS SYSTEM MALFORMATIONS.

Synonyms(10)

Synonym
Patau Syndrome
Trisomy 13
Trisomy 13 Syndromes
Complete Trisomy 13 Syndrome
Mosaic Trisomy 13 Syndrome
Chromosome 13 Duplication
Bartholin-Patau Syndrome
Trisomy 13 Syndrome
Chromosome 13 Trisomy Syndrome
Patau's Syndrome

Research Excerpts

Overview

Excerpt	Reference
"Trisomy 13 (Patau syndrome) is a kind of congenital chromosomal abnormality disease."	( Liu, M; Wan, Q; Xiang, J; Xie, L, 2023)
"Trisomy 13 is one of the most common fetal life limiting diagnosis which is associated with ACC of membranous type scalp."	( Abdulwahab, AH; Al Nefily, RM; Al-Shammari, AA; AlAnazi, RA; AlMatrifi, FR; Ammar, AS, 2023)

Context

Excerpt	Reference
"Trisomy 13 has high occurrence in fetuses or infants from the old aged pregnant women."	( Liu, M; Wan, Q; Xiang, J; Xie, L, 2023)

Research

Studies (25)

Timeframe	Studies, This Condition (%)	All Conditions %
pre-1990	7 (28.00)	23.3326
1990's	0 (0.00)	12.5806
2000's	0 (0.00)	18.1394
2010's	11 (44.00)	28.8240
2020's	7 (28.00)	9.53

Drug	Relationship Strength	Studies
salicylic acid	low	2
cytosine	low	1
hexachlorocyclohexane	low	1
3,4-methylenedioxyamphetamine	low	1
busulfan	low	1
caffeine	low	1
diazoxide	low	2
valproic acid	low	1
2-propanol	low	1
apnea	low	1
trichlormethiazide	low	1
trifluoperazine	low	1
estriol	low	1
thymidine	low	1
inositol 3-phosphate	low	1
riboflavin	low	1
sphingosine	low	1
phenylephrine hydrochloride	low	1
sybr green i	low	1
exudates	low	1
guanosine	low	1
eye	low	2

Protein Targets (411)

Protein	Potency Measurements	Inhibition Measurements	Activation Measurements	Drugs
hypoxia-inducible factor 1 alpha subunit	3	0	0	3
RAR-related orphan receptor gamma	6	0	0	6
GLI family zinc finger 3	6	0	0	6
AR protein	7	0	0	7
aldehyde dehydrogenase 1 family, member A1	7	0	0	7
retinoic acid nuclear receptor alpha variant 1	7	0	0	7
retinoid X nuclear receptor alpha	6	0	0	6
estrogen nuclear receptor alpha	11	0	0	11
peroxisome proliferator-activated receptor delta	3	0	0	3
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a	3	0	0	3
activating transcription factor 6	3	0	0	3
v-jun sarcoma virus 17 oncogene homolog (avian)	4	0	0	4
Histone H2A.x	1	0	0	1
thyroid hormone receptor beta isoform a	6	0	0	6
heat shock protein beta-1	3	0	0	3
nuclear factor erythroid 2-related factor 2 isoform 1	8	0	0	8
lamin isoform A-delta10	9	0	0	9
Voltage-dependent calcium channel gamma-2 subunit	4	0	0	4
Glutamate receptor 2	4	0	0	6
5-hydroxytryptamine receptor 2C	0	1	2	3
5-hydroxytryptamine receptor 2A	0	1	2	3
5-hydroxytryptamine receptor 1A	0	0	1	1
Sodium-dependent noradrenaline transporter	0	2	0	2
Sodium-dependent dopamine transporter	0	0	1	1
5-hydroxytryptamine receptor 1B	0	0	1	1
5-hydroxytryptamine receptor 1D	0	0	1	1
5-hydroxytryptamine receptor 1F	0	0	1	1
5-hydroxytryptamine receptor 2B	0	1	2	3
5-hydroxytryptamine receptor 6	0	0	1	1
Sodium-dependent serotonin transporter	0	4	1	5
Sodium-dependent serotonin transporter	0	1	1	2
5-hydroxytryptamine receptor 7	0	0	1	1
5-hydroxytryptamine receptor 5A	0	0	1	1
5-hydroxytryptamine receptor 5B	0	0	1	1
5-hydroxytryptamine receptor 3A	0	0	1	1
Sodium-dependent dopamine transporter	0	2	0	2
5-hydroxytryptamine receptor 4	0	0	1	1
5-hydroxytryptamine receptor 3B	0	0	1	1
thioredoxin reductase	3	0	0	3
ATAD5 protein, partial	5	0	0	5
TDP1 protein	8	0	0	8
Microtubule-associated protein tau	3	0	0	3
estrogen-related nuclear receptor alpha	6	0	0	6
arylsulfatase A	1	0	0	1
euchromatic histone-lysine N-methyltransferase 2	6	0	0	6
Bloom syndrome protein isoform 1	4	0	0	4
D(1A) dopamine receptor	3	0	0	3
neuropeptide S receptor isoform A	1	0	0	1
Chain A, JmjC domain-containing histone demethylation protein 3A	2	0	0	2
Chain A, 2-oxoglutarate Oxygenase	3	0	0	3
15-lipoxygenase, partial	3	0	0	3
apical membrane antigen 1, AMA1	3	0	0	3
thyroid stimulating hormone receptor	4	0	0	4
cytochrome P450 family 3 subfamily A polypeptide 4	3	0	0	3
EWS/FLI fusion protein	3	0	0	3
glucocorticoid receptor [Homo sapiens]	9	0	0	9
pregnane X nuclear receptor	4	0	0	4
aryl hydrocarbon receptor	2	0	0	2
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a	3	0	0	3
thyroid hormone receptor beta isoform 2	4	0	0	4
ubiquitin carboxyl-terminal hydrolase 2 isoform a	2	0	0	2
geminin	10	0	0	10
lethal factor (plasmid)	4	0	0	4
ATP-binding cassette sub-family C member 3	0	3	0	3
Multidrug resistance-associated protein 4	0	3	0	3
Bile salt export pump	0	8	0	8
Matrix metalloproteinase-9	0	1	0	1
Disintegrin and metalloproteinase domain-containing protein 17	1	0	0	1
Canalicular multispecific organic anion transporter 1	0	3	0	3
Chain A, Glycogen Phosphorylase	0	1	0	1
Chain A, Glycogen phosphorylase, liver form	0	0	1	1
Chain A, glycogen phosphorylase, liver form	0	0	1	1
Chain A, Glycogen phosphorylase, liver form	0	0	1	1
Chain A, Glycogen phosphorylase, liver form	0	0	1	1
Chain A, Chitinase	0	1	0	1
phosphopantetheinyl transferase	3	0	0	3
GLS protein	2	0	0	2
nuclear receptor subfamily 1, group I, member 3	3	0	0	3
farnesoid X nuclear receptor	4	0	0	4
thyroid stimulating hormone receptor	4	0	0	4
atrial natriuretic peptide receptor 1 precursor	1	0	0	1
chromobox protein homolog 1	3	0	0	3
DNA polymerase beta	2	0	0	2
nuclear receptor ROR-gamma isoform 1	2	0	0	2
DNA polymerase kappa isoform 1	2	0	0	2
muscarinic acetylcholine receptor M1	3	0	0	3
Potassium channel subfamily K member 2	0	0	1	1
Glycogen phosphorylase, muscle form	0	1	0	1
Renin	0	1	0	1
Carbonic anhydrase 1	0	4	0	5
Carbonic anhydrase 2	0	4	0	5
Cholinesterase	0	1	0	1
Glycogen phosphorylase, liver form	0	1	0	1
Glycogen phosphorylase, muscle form	0	1	0	1
Replicase polyprotein 1ab	0	1	0	1
Adenosine receptor A3	0	1	0	1
Replicase polyprotein 1ab	0	1	0	1
Amine oxidase [flavin-containing] A	0	1	0	1
Acetylcholinesterase	0	2	0	2
Adenosine receptor A1	0	2	0	3
Amine oxidase [flavin-containing] B	0	2	0	2
cAMP-specific 3',5'-cyclic phosphodiesterase 4A	0	1	0	1
Adenosine receptor A3	0	1	0	1
Adenosine receptor A2a	0	2	1	4
Adenosine receptor A2b	0	1	0	2
Adenosine receptor A2b	0	2	0	3
Adenosine receptor A1	0	1	1	4
Adenosine receptor A2a	0	2	0	4
Vasopressin V2 receptor	0	0	0	1
Serine/threonine-protein kinase mTOR	0	1	0	1
Adenosine receptor A2a	0	1	0	1
Adenosine receptor A1	0	1	0	1
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	0	1	0	1
DNA-dependent protein kinase catalytic subunit	0	2	0	2
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B	0	1	0	1
Adenylate cyclase type 1	0	0	0	1
Chitotriosidase-1	0	1	0	1
Serine-protein kinase ATM	0	1	0	1
Serine/threonine-protein kinase ATR	0	1	0	1
Adenosine receptor A2b	0	1	0	2
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C	0	1	0	1
Palmitoleoyl-protein carboxylesterase NOTUM	0	1	2	3
Endochitinase B1	0	1	0	1
Muscarinic acetylcholine receptor	0	0	0	1
Phosphodiesterase	0	1	0	1
Broad substrate specificity ATP-binding cassette transporter ABCG2	0	1	0	1
Guanine deaminase	0	1	0	1
ATP-dependent phosphofructokinase	2	0	0	2
IDH1	3	0	0	3
Deoxycytidine kinase	0	0	0	1
Chain A, Beta-lactamase	2	0	0	2
Chain A, Ferritin light chain	2	0	0	2
regulator of G-protein signaling 4	3	0	0	3
cytochrome P450 2D6 isoform 1	2	0	0	2
importin subunit beta-1 isoform 1	1	0	0	1
snurportin-1	1	0	0	1
GTP-binding nuclear protein Ran isoform 1	1	0	0	1
peripheral myelin protein 22	4	0	0	4
survival motor neuron protein isoform d	4	0	0	4
cytochrome P450 3A4 isoform 1	4	0	0	4
histone acetyltransferase KAT2A isoform 1	4	0	0	4
Gamma-aminobutyric acid receptor subunit pi	4	0	0	4
Coagulation factor VII	0	1	0	1
Tissue factor	0	2	0	2
Gamma-aminobutyric acid receptor subunit beta-1	4	0	0	4
Gamma-aminobutyric acid receptor subunit delta	4	0	0	4
Gamma-aminobutyric acid receptor subunit gamma-2	4	0	0	4
Glutamate receptor 1	0	0	0	2
Glutamate receptor 3	0	0	0	2
Glutamate receptor 4	0	0	0	2
Gamma-aminobutyric acid receptor subunit alpha-5	4	0	0	4
Gamma-aminobutyric acid receptor subunit alpha-3	4	0	0	4
Gamma-aminobutyric acid receptor subunit gamma-1	4	0	0	4
Gamma-aminobutyric acid receptor subunit alpha-2	4	0	0	4
Gamma-aminobutyric acid receptor subunit alpha-4	4	0	0	4
Gamma-aminobutyric acid receptor subunit gamma-3	4	0	0	4
Gamma-aminobutyric acid receptor subunit alpha-6	4	0	0	4
Nicotinamide phosphoribosyltransferase	0	0	1	1
Gamma-aminobutyric acid receptor subunit alpha-1	4	0	0	4
Gamma-aminobutyric acid receptor subunit beta-3	4	0	0	4
Gamma-aminobutyric acid receptor subunit beta-2	4	0	0	4
ATP-binding cassette sub-family C member 8	0	1	1	2
ATP-sensitive inward rectifier potassium channel 11	0	1	1	2
GABA theta subunit	4	0	0	4
Gamma-aminobutyric acid receptor subunit epsilon	4	0	0	4
estrogen receptor 2 (ER beta)	3	0	0	3
progesterone receptor	3	0	0	3
Estrogen receptor	0	2	0	2
Glucocorticoid receptor	0	2	0	2
Sex hormone-binding globulin	0	0	1	1
Glycine receptor subunit alpha-1	0	2	0	2
Corticosteroid-binding globulin	0	1	0	1
Polyunsaturated fatty acid lipoxygenase ALOX15	0	1	0	1
Androgen receptor	0	2	0	2
UDP-glucuronosyltransferase 2B7	0	1	0	3
Glycine receptor subunit beta	0	2	0	2
Glycine receptor subunit alpha-2	0	2	0	2
Glycine receptor subunit alpha-3	0	2	0	2
Alpha-synuclein	0	1	0	1
Solute carrier organic anion transporter family member 1A1	0	1	0	1
Lanosterol 14-alpha demethylase	0	0	1	1
Olfactory receptor 51E2	0	0	1	1
UDP-glucuronosyltransferase 1A10	0	0	0	1
USP1 protein, partial	3	0	0	3
thioredoxin glutathione reductase	1	0	0	1
Voltage-dependent calcium channel subunit alpha-2/delta-1	0	1	0	1
Chain A, Membrane lipoprotein tmpC	0	0	1	1
Chain A, Membrane lipoprotein tmpC	0	0	1	1
Chain A, Membrane lipoprotein tmpC	0	0	1	1
Chain A, ATP-DEPENDENT DNA HELICASE Q1	2	0	0	2
Purine nucleoside phosphorylase	0	0	0	1
Adenosylhomocysteinase	0	1	0	2
pregnane X receptor	2	0	0	2
SMAD family member 2	2	0	0	2
SMAD family member 3	2	0	0	2
caspase 7, apoptosis-related cysteine protease	1	0	0	1
peroxisome proliferator activated receptor gamma	4	0	0	4
vitamin D (1,25- dihydroxyvitamin D3) receptor	2	0	0	2
caspase-3	1	0	0	1
Cellular tumor antigen p53	4	0	0	4
Spike glycoprotein	3	0	0	3
glp-1 receptor, partial	2	0	0	2
GALC protein	1	0	0	1
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)	1	0	0	1
beta-2 adrenergic receptor	1	0	0	1
lysosomal alpha-glucosidase preproprotein	1	0	0	1
mu-type opioid receptor isoform MOR-1	0	0	1	1
Vpr	1	0	0	1
5-hydroxytryptamine receptor 2A	0	0	1	1
Neuronal acetylcholine receptor subunit alpha-4	1	0	0	1
Neuronal acetylcholine receptor subunit beta-2	1	0	0	1
Chain A, TYROSYL-DNA PHOSPHODIESTERASE	2	0	0	2
Chain A, 6,7-Dimethyl-8-ribityllumazine Synthase	0	0	1	1
Chain B, 6,7-Dimethyl-8-ribityllumazine Synthase	0	0	1	1
Chain A, Breast cancer type 1 susceptibility protein	1	0	0	1
Chain H, Immunoglobulin Igg1 Heavy chain	0	0	1	1
Chain L, Immunoglobulin Igg1 Lambda Light Chain	0	0	1	1
Chain A, HADH2 protein	2	0	0	2
Chain B, HADH2 protein	2	0	0	2
Chain A, DODECIN	0	0	1	1
Chain A, DODECIN	0	0	1	1
Chain C, DODECIN	0	0	1	1
Chain E, DODECIN	0	0	1	1
acetylcholinesterase	1	0	0	1
NPYLR7B	0	0	1	1
cytochrome P450 2D6	1	0	0	1
thyrotropin-releasing hormone receptor	1	0	0	1
tumor necrosis factor	1	0	0	1
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 1	2	0	0	2
mitogen-activated protein kinase 1	3	0	0	3
nuclear factor NF-kappa-B p105 subunit isoform 1	1	0	0	1
caspase-1 isoform alpha precursor	1	0	0	1
Riboflavin-binding protein	0	1	1	2
60 kDa chaperonin	0	1	0	1
60 kDa heat shock protein, mitochondrial	0	1	0	1
Caspase-7	1	0	0	1
10 kDa heat shock protein, mitochondrial	0	1	0	1
Inositol monophosphatase 1	2	0	0	2
Thiosulfate sulfurtransferase	0	1	0	1
60 kDa chaperonin	0	1	0	1
10 kDa chaperonin	0	1	0	1
chaperonin-containing TCP-1 beta subunit homolog	1	0	0	1
Estrogen receptor beta	0	0	0	1
Inhibitor of nuclear factor kappa-B kinase subunit beta	0	0	0	1
Solute carrier family 22 member 6	0	1	0	1
Polyphenol oxidase 2	0	1	0	2
Carbonic anhydrase 12	0	2	0	3
5'-AMP-activated protein kinase subunit beta-2	0	0	0	1
Bile salt export pump	0	2	0	2
Albumin	0	1	0	1
Polymerase acidic protein	0	0	1	1
Carbonic anhydrase 3	0	2	0	2
Stromelysin-1	0	0	1	1
Tyrosine-protein phosphatase YopH	0	1	0	1
High mobility group protein B1	0	0	1	1
Aldo-keto reductase family 1 member B1	0	1	0	1
Prolyl 4-hydroxylase subunit alpha-1	0	1	0	1
Tyrosine-protein phosphatase non-receptor type 1	0	1	0	3
Estrogen receptor	0	0	0	1
Carbonic anhydrase 4	0	2	0	3
Prostaglandin G/H synthase 1	0	1	0	1
Carbonic anhydrase 6	0	2	0	3
Cystathionine gamma-lyase	0	1	0	1
Carbonic anhydrase 5A, mitochondrial	0	2	0	3
Prostaglandin G/H synthase 2	0	1	0	1
Carbonic anhydrase 7	0	2	0	3
5'-AMP-activated protein kinase subunit gamma-1	0	0	0	1
5'-AMP-activated protein kinase catalytic subunit alpha-2	0	0	0	1
Xanthine dehydrogenase/oxidase	0	1	0	1
5'-AMP-activated protein kinase catalytic subunit alpha-1	0	0	0	1
Carbonic anhydrase 9	0	2	0	3
Carbonic anhydrase	0	1	0	1
Solute carrier family 22 member 6	0	1	0	1
Solute carrier family 22 member 7	0	0	0	1
Nicotinate phosphoribosyltransferase	0	1	0	1
Solute carrier family 22 member 20	0	1	0	1
Solute carrier family 22 member 8	0	1	0	1
Solute carrier family 22 member 6	0	1	0	1
Ubiquitin-like domain-containing CTD phosphatase 1	0	1	0	1
Carbonic anhydrase 15	0	1	0	1
Carbonic anhydrase 13	0	2	0	3
5'-AMP-activated protein kinase subunit gamma-3	0	0	0	1
5'-AMP-activated protein kinase subunit gamma-2	0	0	0	1
Carbonic anhydrase 14	0	2	0	3
Carbonic anhydrase 5B, mitochondrial	0	2	0	3
5'-AMP-activated protein kinase subunit beta-1	0	0	0	1
Chain A, Cruzipain	1	0	0	1
Luciferase	2	0	0	2
acid sphingomyelinase	1	0	0	1
endonuclease IV	1	0	0	1
glucocerebrosidase	2	0	0	2
alpha-galactosidase	1	0	0	1
vitamin D3 receptor isoform VDRA	2	0	0	2
potassium voltage-gated channel subfamily H member 2 isoform d	2	0	0	2
C-X-C chemokine receptor type 5 isoform 1	0	1	0	1
ubiquitin-conjugating enzyme E2 N	0	1	0	1
C-C chemokine receptor type 6	0	1	0	1
apelin receptor	0	1	0	1
DNA polymerase eta isoform 1	1	0	0	1
DNA polymerase iota isoform a (long)	1	0	0	1
bcl-2-related protein A1	0	1	0	1
streptokinase A precursor	0	0	1	1
Endoglycoceramidase II	0	0	0	1
Protein kinase C alpha type	0	2	0	2
Estrogen receptor	0	0	1	1
Protein kinase C delta type	0	2	0	2
Protein kinase C epsilon type	0	2	0	2
Protein kinase C zeta type	0	2	0	2
cAMP-dependent protein kinase catalytic subunit alpha	0	1	0	1
Protein kinase C gamma type	0	2	0	2
Protein kinase C beta type	0	2	0	2
Estrogen receptor beta	0	0	1	1
Protein kinase C eta type	0	2	0	2
Sphingosine kinase 2	0	1	0	1
Sphingosine kinase 1	0	1	0	1
Protein kinase C theta type	0	2	0	2
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE	1	0	0	1
Thymidine kinase	0	1	0	2
Thymidine kinase, cytosolic	0	2	0	4
Thymidine kinase	0	1	0	2
Thymidylate synthase	0	0	0	1
Thymidine phosphorylase	0	0	0	1
Polyunsaturated fatty acid 5-lipoxygenase	0	1	0	1
Glucose-6-phosphate 1-dehydrogenase	0	1	0	1
Thymidine phosphorylase	0	0	0	1
Thymidylate kinase	0	1	0	1
Thymidine kinase, cytosolic	0	0	0	2
Thymidine kinase	0	0	0	1
Thymidylate kinase	0	1	0	1
Thymidine kinase	0	1	0	2
Sterol O-acyltransferase 1	0	1	0	1
Thymidine kinase	0	0	0	1
Thymidine kinase	0	0	0	1
G	1	0	0	1
Interferon beta	1	0	0	1
HLA class I histocompatibility antigen, B alpha chain	1	0	0	1
TAR DNA-binding protein 43	1	0	0	1
Inositol hexakisphosphate kinase 1	1	0	0	1
cytochrome P450 2C9, partial	1	0	0	1
Genome polyprotein	0	1	0	1
NFKB1 protein, partial	1	0	0	1
Thrombopoietin	1	0	0	1
Smad3	1	0	0	1
NADPH oxidase 1	0	1	0	1
67.9K protein	1	0	0	1
Snq2p	0	0	0	1
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)	1	0	0	1
NPC intracellular cholesterol transporter 1 precursor	1	0	0	1
cellular tumor antigen p53 isoform a	1	0	0	1
cytochrome P450 2C19 precursor	1	0	0	1
atrial natriuretic peptide receptor 2 precursor	1	0	0	1
ras-related protein Rab-9A	1	0	0	1
serine/threonine-protein kinase mTOR isoform 1	1	0	0	1
M-phase phosphoprotein 8	1	0	0	1
DNA dC->dU-editing enzyme APOBEC-3G isoform 1	1	0	0	1
DNA repair protein RAD52 homolog isoform a	0	0	0	1
Polyunsaturated fatty acid lipoxygenase ALOX15B	1	0	0	1
Ubiquitin carboxyl-terminal hydrolase 1	0	1	0	1
Lysozyme C-1	0	1	0	1
Glycoprotein hormones alpha chain	1	0	0	1
Albumin	0	0	1	1
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1	0	1	0	1
Integrin beta-3	1	0	0	1
Beta-glucuronidase	0	1	0	1
ATP-dependent translocase ABCB1	0	2	0	2
Integrin alpha-IIb	1	0	0	1
Calmodulin-1	0	0	1	1
Angiotensin-converting enzyme	0	2	0	2
Alpha-1B adrenergic receptor	0	1	0	1
Alpha-1D adrenergic receptor	0	1	0	1
Trypanothione reductase	0	2	0	2
C-8 sterol isomerase	0	1	0	1
Pleiotropic ABC efflux transporter of multiple drugs	0	1	0	2
Alpha-1A adrenergic receptor	0	1	0	1
Histamine H2 receptor	1	0	0	1
D(2) dopamine receptor	0	1	1	2
Calmodulin	0	0	1	1
Guanine nucleotide-binding protein G	1	0	0	1
Potassium voltage-gated channel subfamily H member 2	0	2	0	2
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase	0	1	0	1
Nuclear receptor subfamily 3 group C member 3	0	2	0	2
Calcium-dependent protein kinase 4	0	1	0	1
WD repeat-containing protein 48	0	1	0	1
Ataxin-2	2	0	0	2
Sigma non-opioid intracellular receptor 1	0	1	0	1
Emopamil-binding protein-like	0	1	0	1
Cocaine esterase	0	1	0	1
Histone deacetylase 3	0	2	0	2
UDP-glucuronosyltransferase 1A9	0	0	0	1
Aldo-keto reductase family 1 member B1	0	1	0	1
Cytochrome P450 2A6	0	1	0	1
Aldo-keto reductase family 1 member A1	0	1	0	1
UDP-glucuronosyltransferase 1-6	0	0	0	1
Liver carboxylesterase 1	0	1	0	1
Nuclear receptor ROR-gamma	1	0	0	1
Aldo-keto reductase family 1 member A1	0	1	0	1
Histone deacetylase 4	0	2	0	2
Histone deacetylase 1	0	2	0	2
Aldo-keto reductase family 1 member A1	0	1	0	1
Aldo-keto reductase family 1 member B7	0	1	0	1
Sigma non-opioid intracellular receptor 1	0	1	0	1
Histone deacetylase 7	0	2	0	2
Histone deacetylase 2	0	2	0	2
Polyamine deacetylase HDAC10	0	2	0	2
Histone deacetylase 11	0	2	0	2
ATPase family AAA domain-containing protein 5	1	0	0	1
Histone deacetylase 8	0	2	0	2
NAD-dependent protein deacylase sirtuin-5, mitochondrial	0	1	0	1
Histone deacetylase 6	0	2	0	2
Histone deacetylase 9	0	2	0	2
Histone deacetylase 5	0	2	0	2
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

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