Any monohydroxylated icosanoid having four double bonds.
ChEBI ID: 36275
| Member | Definition | Role |
|---|---|---|
| 12-hydroxy-5,8,10,14-eicosatetraenoic acid | A HETE having a (12S)-hydroxy group and (5Z)-, (8Z)-, (10E)- and (14Z)-double bonds. | 12(S)-HETE |
| 20-hydroxy-5,8,11,14-eicosatetraenoic acid | A HETE that consists of arachidonic acid bearing a hydroxy substituent at position 20. | 20-HETE |
| 5-hydroxy-6,8,11,14-eicosatetraenoic acid | A HETE having a (5S)-hydroxy group and (6E)-, (8Z)-, (11Z)- and (14Z)-double bonds. | 5(S)-HETE |
| Timeframe | Studies, Drugs in This Class (%) | All Drugs % |
|---|---|---|
| pre-1990 | 290 (23.05) | 18.7374 |
| 1990's | 303 (24.09) | 18.2507 |
| 2000's | 350 (27.82) | 29.6817 |
| 2010's | 263 (20.91) | 24.3611 |
| 2020's | 52 (4.13) | 2.80 |
| Publication Type | Studies, Drugs in This Class (%) | All Drugs (%) |
|---|---|---|
| Trials | 18 (1.39%) | 5.53% |
| Reviews | 83 (6.42%) | 6.00% |
| Case Studies | 0 (0.00%) | 4.05% |
| Observational | 2 (0.15%) | 0.25% |
| Other | 1,190 (92.03%) | 84.16% |