trifluoperazine has been researched along with Neoplasms in 19 studies
Neoplasms: New abnormal growth of tissue. Malignant neoplasms show a greater degree of anaplasia and have the properties of invasion and metastasis, compared to benign neoplasms.
| Excerpt | Relevance | Reference |
|---|---|---|
| " In addition, characterization of the UGT1A locus and genetic studies directed at understanding the role of bilirubin glucuronidation and the biochemical basis of the clinical symptoms found in unconjugated hyperbilirubinemia have uncovered the structural gene polymorphisms associated with Crigler-Najjar's and Gilbert's syndrome." | 4.80 | Human UDP-glucuronosyltransferases: metabolism, expression, and disease. ( Strassburg, CP; Tukey, RH, 2000) |
| "As numerous cancers--e." | 1.34 | Consideration of use of phenothiazines in particular trifluorperazine for epidermal growth factor receptor associated cancers. ( Altschuler, EL; Kast, RE, 2007) |
| "Trifluoperazine was administered in divided doses orally on days 1 through 6, with dose escalation from 20 to 100 mg/d." | 1.27 | Clinical modulation of doxorubicin resistance by the calmodulin-inhibitor, trifluoperazine: a phase I/II trial. ( Budd, GT; Bukowski, RM; Ganapathi, R; Midha, KK; Miller, RL; Purvis, J; Shepard, K; Weick, JK, 1988) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (31.58) | 18.7374 |
| 1990's | 1 (5.26) | 18.2507 |
| 2000's | 3 (15.79) | 29.6817 |
| 2010's | 7 (36.84) | 24.3611 |
| 2020's | 2 (10.53) | 2.80 |
| Authors | Studies |
|---|---|
| Tukey, RH | 1 |
| Strassburg, CP | 1 |
| Finlay, MR | 1 |
| Griffin, RJ | 1 |
| Kastrinsky, DB | 1 |
| Sangodkar, J | 1 |
| Zaware, N | 1 |
| Izadmehr, S | 1 |
| Dhawan, NS | 1 |
| Narla, G | 1 |
| Ohlmeyer, M | 1 |
| Lin, R | 1 |
| Elf, S | 1 |
| Shan, C | 1 |
| Kang, HB | 1 |
| Ji, Q | 1 |
| Zhou, L | 1 |
| Hitosugi, T | 1 |
| Zhang, L | 1 |
| Zhang, S | 1 |
| Seo, JH | 1 |
| Xie, J | 1 |
| Tucker, M | 1 |
| Gu, TL | 1 |
| Sudderth, J | 1 |
| Jiang, L | 1 |
| Mitsche, M | 1 |
| DeBerardinis, RJ | 1 |
| Wu, S | 1 |
| Li, Y | 1 |
| Mao, H | 1 |
| Chen, PR | 1 |
| Wang, D | 1 |
| Chen, GZ | 1 |
| Hurwitz, SJ | 1 |
| Lonial, S | 1 |
| Arellano, ML | 1 |
| Khoury, HJ | 1 |
| Khuri, FR | 1 |
| Lee, BH | 1 |
| Lei, Q | 1 |
| Brat, DJ | 1 |
| Ye, K | 1 |
| Boggon, TJ | 1 |
| He, C | 1 |
| Kang, S | 1 |
| Fan, J | 1 |
| Chen, J | 1 |
| Korzhnev, DM | 1 |
| Hadden, MK | 1 |
| Peterková, L | 1 |
| Kmoníčková, E | 1 |
| Ruml, T | 1 |
| Rimpelová, S | 1 |
| Ma, Y | 1 |
| Li, L | 1 |
| Mo, L | 1 |
| Wang, X | 1 |
| Liu, C | 2 |
| Wu, Y | 1 |
| Santofimia-Castaño, P | 1 |
| Xia, Y | 1 |
| Lan, W | 1 |
| Zhou, Z | 1 |
| Huang, C | 1 |
| Peng, L | 1 |
| Soubeyran, P | 1 |
| Velázquez-Campoy, A | 1 |
| Abián, O | 1 |
| Rizzuti, B | 1 |
| Neira, JL | 1 |
| Iovanna, J | 1 |
| Qi, L | 1 |
| Ding, Y | 1 |
| Tafani, M | 2 |
| Schito, L | 2 |
| Anwar, T | 1 |
| Indelicato, M | 2 |
| Sale, P | 1 |
| Di Vito, M | 1 |
| Morgante, E | 1 |
| Beraldi, R | 1 |
| Makovec, F | 1 |
| Letari, O | 1 |
| Caselli, G | 1 |
| Spadafora, C | 1 |
| Pucci, B | 2 |
| Russo, MA | 2 |
| Reali, V | 1 |
| Aventaggiato, M | 1 |
| Mazzarino, MC | 1 |
| Stivala, F | 1 |
| Fini, M | 1 |
| Kast, RE | 1 |
| Altschuler, EL | 1 |
| Hickie, RA | 1 |
| Wei, JW | 1 |
| Blyth, LM | 1 |
| Wong, DY | 1 |
| Klaassen, DJ | 1 |
| Von Hoff, DD | 1 |
| Goldstein, LJ | 1 |
| Pastan, I | 1 |
| Gottesman, MM | 1 |
| Hait, WN | 1 |
| Morris, S | 1 |
| Lazo, JS | 1 |
| Figlin, RJ | 1 |
| Durivage, HJ | 1 |
| White, K | 1 |
| Schwartz, PE | 1 |
| Miller, RL | 1 |
| Bukowski, RM | 1 |
| Budd, GT | 1 |
| Purvis, J | 1 |
| Weick, JK | 1 |
| Shepard, K | 1 |
| Midha, KK | 1 |
| Ganapathi, R | 1 |
| Wada, T | 1 |
| Kohno, N | 1 |
| Saitoh, Y | 1 |
| Akiyama, S | 1 |
| Shiraishi, N | 1 |
| Kuratomi, Y | 1 |
| Nakagawa, M | 1 |
| Kuwano, M | 1 |
7 reviews available for trifluoperazine and Neoplasms
| Article | Year |
|---|---|
Human UDP-glucuronosyltransferases: metabolism, expression, and disease.
Topics: Autoimmunity; Chromosome Mapping; Glucuronides; Glucuronosyltransferase; Humans; Hyperbilirubinemia; | 2000 |
Modulation of DNA repair by pharmacological inhibitors of the PIKK protein kinase family.
Topics: Animals; Ataxia Telangiectasia Mutated Proteins; Cell Cycle Proteins; DNA; DNA Repair; DNA-Activated | 2012 |
6-Phosphogluconate dehydrogenase links oxidative PPP, lipogenesis and tumour growth by inhibiting LKB1-AMPK signalling.
Topics: AMP-Activated Protein Kinase Kinases; AMP-Activated Protein Kinases; Humans; Lipogenesis; Neoplasms; | 2015 |
Targeting the Translesion Synthesis Pathway for the Development of Anti-Cancer Chemotherapeutics.
Topics: Animals; Antineoplastic Agents; Cell Survival; DNA Damage; DNA-Directed DNA Polymerase; Dose-Respons | 2016 |
Sarco/Endoplasmic Reticulum Calcium ATPase Inhibitors: Beyond Anticancer Perspective.
Topics: Animals; Antineoplastic Agents; Enzyme Inhibitors; Gene Regulatory Networks; Humans; Neoplasms; Prot | 2020 |
Cations and calmodulin in normal and neoplastic cell growth regulation.
Topics: Breast Neoplasms; Calcium; Calmodulin; Cell Division; Cell Line; Female; Humans; Magnesium; Neoplasm | 1983 |
Multidrug resistance in human cancer.
Topics: Animals; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Carrier Pro | 1992 |
12 other studies available for trifluoperazine and Neoplasms
| Article | Year |
|---|---|
Reengineered tricyclic anti-cancer agents.
Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Cell Survival; Dibenzazepines; Heterocyclic Compou | 2015 |
Preparation and anti-tumor effects of mesoporous silica nanoparticles loaded with trifluoperazine.
Topics: Animals; Drug Delivery Systems; Mice; Nanoparticles; Neoplasms; Silicon Dioxide; Trifluoperazine | 2023 |
Ligand-based design identifies a potent NUPR1 inhibitor exerting anticancer activity via necroptosis.
Topics: Animals; Antineoplastic Agents; Basic Helix-Loop-Helix Transcription Factors; Hep G2 Cells; Humans; | 2019 |
Potential antitumor mechanisms of phenothiazine drugs.
Topics: Antineoplastic Agents; Cell Proliferation; Chlorpromazine; Computational Biology; Drug Delivery Syst | 2013 |
Induction of autophagic cell death by a novel molecule is increased by hypoxia.
Topics: Adenine; Amidines; Androstadienes; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic | 2008 |
Role of hypoxia and autophagy in MDA-MB-231 invasiveness.
Topics: Adenine; Autophagy; Cell Hypoxia; Cell Line, Tumor; Cell Migration Assays; Cell Movement; Cell Survi | 2010 |
Consideration of use of phenothiazines in particular trifluorperazine for epidermal growth factor receptor associated cancers.
Topics: ErbB Receptors; Humans; Models, Biological; Neoplasms; Phenothiazines; Trifluoperazine | 2007 |
Use of daunorubicin in patients with solid tumors.
Topics: Calcium Channel Blockers; Daunorubicin; Drug Administration Schedule; Drug Evaluation; Female; Human | 1984 |
Phase I trial of combined therapy with bleomycin and the calmodulin antagonist, trifluoperazine.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Drug Administration Schedule | 1989 |
Clinical modulation of doxorubicin resistance by the calmodulin-inhibitor, trifluoperazine: a phase I/II trial.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Calmodulin; Doxorubicin; Drug Evaluatio | 1988 |
[Effect of calmodulin inhibitor on proliferation and doxorubicin-sensitivity in cultured cancer cells].
Topics: Calmodulin; Doxorubicin; Drug Screening Assays, Antitumor; Humans; Neoplasms; Stimulation, Chemical; | 1988 |
Circumvention of multiple-drug resistance in human cancer cells by thioridazine, trifluoperazine, and chlorpromazine.
Topics: Calmodulin; Cell Line; Chlorpromazine; Daunorubicin; Drug Resistance; Humans; KB Cells; Lysosomes; N | 1986 |