Classes > C-terminal boronic acid peptide
Page last updated: 2024-08-05 12:38:18
C-terminal boronic acid peptide
A member of the class of boronic acids that is any peptide in which the carboxy group at the C-terminus has been replaced by a borono (-B(OH)2) group.
ChEBI ID: 140517
Members (2)
| Member | Definition | Role |
|---|
| acetylphenylalanyl-prolyl-boroarginine | A C-terminal boronic acid petide that is N-acetyl-D-phenylalanyl-L-prolyl-L-arginine in which the C-termnal carboxy group has been replaced by a borono (-B(OH)2) group. A thrombin (Factor IIa) inhibitor, thereby acting as an anticoagulant. | Ac-(D)Phe-Pro-boroArg-OH |
| delanzomib | A C-terminal boronic acid peptide inhibitor which induces apoptosis in multiple myeloma, hematological and solid tumor cell lines. | delanzomib |
Research
Studies (66)
| Timeframe | Studies, Drugs in This Class (%) | All Drugs % |
|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 25 (37.88) | 18.2507 |
| 2000's | 6 (9.09) | 29.6817 |
| 2010's | 26 (39.39) | 24.3611 |
| 2020's | 9 (13.64) | 2.80 |
Study Types
| Publication Type | Studies, Drugs in This Class (%) | All Drugs (%) |
|---|
| Trials | 1 (1.49%) | 5.53% |
| Reviews | 11 (16.42%) | 6.00% |
| Case Studies | 0 (0.00%) | 4.05% |
| Observational | 0 (0.00%) | 0.25% |
| Other | 55 (82.09%) | 84.16% |