Page last updated: 2024-08-05 13:29:00

germacrane sesquiterpenoid

Any sesquiterpenoid having a germacrane skeleton.

ChEBI ID: 68588

Members (7)

MemberDefinitionRole
curdioneGermacr-1(10)-ene-5,8-dione
dehydrocurdione(6E,10S)-6,10-Dimethyl-3-propan-2-ylidenecyclodec-6-ene-1,4-dione
furanodienone(5E,9E)-3,6,10-Trimethyl-8,11-dihydro-7H-cyclodeca[b]furan-4-one
germacra-1(10),4,11(13)-trien-12-oic acidA germacrane sesquiterpenoid derived from germacrane by dehydrogenation between the 1-10, 4-5, and 11-13 positions, and by oxidation of the methyl group at position 12 to the corresponding carboxylic acid.germacra-1(10),4,11(13)-trien-12-oic acid
germacradienolA germacrane sesquiterpenoid obtained from germacrane by hydroxylation at C(11) together with dehydrogenation across the C(1)-C(10) and C(5)-C(6) bonds.(1E,4S,5E,7R)-germacra-1(10),5-dien-11-ol
germacroneA germacrane sesquiterpenoid that has formula C15H22O. It is a natural product found in traditional medicinal plants of the family Zingiberaceae. The compound exhibits a range of pharmacological activities including anti-inflammatory, anticancer, antiviral, anti-androgenic, antioxidant, antimicrobial, antifungal, neuroprotective and insecticidal activities.(E,E)-germacrone
zederone(3S,8E)-5,9,14-Trimethyl-4,12-dioxatricyclo[9.3.0.03,5]tetradeca-1(11),8,13-trien-2-one

Research

Studies (121)

TimeframeStudies, Drugs in This Class (%)All Drugs %
pre-19902 (1.65)18.7374
1990's1 (0.83)18.2507
2000's24 (19.83)29.6817
2010's68 (56.20)24.3611
2020's26 (21.49)2.80

Study Types

Publication TypeStudies, Drugs in This Class (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews4 (2.84%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other137 (97.16%)84.16%