Page last updated: 2024-08-05 13:29:00
germacrane sesquiterpenoid
Any sesquiterpenoid having a germacrane skeleton.
ChEBI ID: 68588
Members (7)
Member | Definition | Role |
---|---|---|
curdione | Germacr-1(10)-ene-5,8-dione | |
dehydrocurdione | (6E,10S)-6,10-Dimethyl-3-propan-2-ylidenecyclodec-6-ene-1,4-dione | |
furanodienone | (5E,9E)-3,6,10-Trimethyl-8,11-dihydro-7H-cyclodeca[b]furan-4-one | |
germacra-1(10),4,11(13)-trien-12-oic acid | A germacrane sesquiterpenoid derived from germacrane by dehydrogenation between the 1-10, 4-5, and 11-13 positions, and by oxidation of the methyl group at position 12 to the corresponding carboxylic acid. | germacra-1(10),4,11(13)-trien-12-oic acid |
germacradienol | A germacrane sesquiterpenoid obtained from germacrane by hydroxylation at C(11) together with dehydrogenation across the C(1)-C(10) and C(5)-C(6) bonds. | (1E,4S,5E,7R)-germacra-1(10),5-dien-11-ol |
germacrone | A germacrane sesquiterpenoid that has formula C15H22O. It is a natural product found in traditional medicinal plants of the family Zingiberaceae. The compound exhibits a range of pharmacological activities including anti-inflammatory, anticancer, antiviral, anti-androgenic, antioxidant, antimicrobial, antifungal, neuroprotective and insecticidal activities. | (E,E)-germacrone |
zederone | (3S,8E)-5,9,14-Trimethyl-4,12-dioxatricyclo[9.3.0.03,5]tetradeca-1(11),8,13-trien-2-one |
Research
Studies (121)
Timeframe | Studies, Drugs in This Class (%) | All Drugs % |
---|---|---|
pre-1990 | 2 (1.65) | 18.7374 |
1990's | 1 (0.83) | 18.2507 |
2000's | 24 (19.83) | 29.6817 |
2010's | 68 (56.20) | 24.3611 |
2020's | 26 (21.49) | 2.80 |
Study Types
Publication Type | Studies, Drugs in This Class (%) | All Drugs (%) |
---|---|---|
Trials | 0 (0.00%) | 5.53% |
Reviews | 4 (2.84%) | 6.00% |
Case Studies | 0 (0.00%) | 4.05% |
Observational | 0 (0.00%) | 0.25% |
Other | 137 (97.16%) | 84.16% |