trifluoperazine has been researched along with Leukemia L 1210 in 9 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| " Results suggest that: (a) TFP in combination with low concentrations DOX can induce the selection of cells with the multidrug resistant phenotype; and (b) characteristics of cells selected for resistance to DOX or DOX plus TFP are comparable." | 1.29 | Calmodulin inhibitor trifluoperazine in combination with doxorubicin induces the selection of tumour cells with the multidrug resistant phenotype. ( Ford, J; Ganapathi, R; Grabowski, D; Kamath, N, 1993) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (33.33) | 18.7374 |
| 1990's | 6 (66.67) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kamath, N | 3 |
| Grabowski, D | 6 |
| Ford, J | 4 |
| Ganapathi, R | 6 |
| Kuo, T | 1 |
| Teeter, L | 1 |
| Constantinou, A | 1 |
| Anderson, A | 1 |
| Drake, F | 1 |
| Kerrigan, D | 1 |
| Pommier, Y | 1 |
| Hoeltge, G | 1 |
| Neelon, R | 1 |
| Pommerenke, EW | 1 |
| Osswald, H | 1 |
| Hahn, EW | 1 |
| Volm, M | 1 |
| Kennedy, KA | 2 |
| Hait, WN | 2 |
| Lazo, JS | 2 |
| Braun, ID | 1 |
| Meandzija, B | 1 |
9 other studies available for trifluoperazine and Leukemia L 1210
| Article | Year |
|---|---|
Calmodulin inhibitor trifluoperazine in combination with doxorubicin induces the selection of tumour cells with the multidrug resistant phenotype.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; ATP Binding Cassette Transporter, Subfamily | 1993 |
Relationship between expression of P-glycoprotein and efficacy of trifluoperazine in multidrug-resistant cells.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Blotting, Southern; Cell Survival; | 1991 |
Effect of the calmodulin inhibitor trifluoperazine on phosphorylation of P-glycoprotein and topoisomerase II: relationship to modulation of subcellular distribution, DNA damage and cytotoxicity of doxorubicin in multidrug resistant L1210 mouse leukemia ce
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Calmodulin; Cell Nucleus; Densitom | 1991 |
Trifluoperazine modulation of resistance to the topoisomerase II inhibitor etoposide in doxorubicin resistant L1210 murine leukemia cells.
Topics: Animals; Blotting, Western; Cell Survival; DNA; DNA Damage; DNA-Binding Proteins; Dose-Response Rela | 1991 |
Modulation of doxorubicin-induced chromosomal damage by calmodulin inhibitors and its relationship to cytotoxicity in progressively doxorubicin-resistant tumor cells.
Topics: Animals; Benzimidazoles; Calmodulin; Cell Survival; Chromosome Aberrations; Dose-Response Relationsh | 1990 |
Activity of various amphiphilic agents in reversing multidrug resistance of L 1210 cells.
Topics: Animals; Drug Resistance; Ethylamines; Hycanthone; Leukemia L1210; Phenotype; Piperidines; Quinidine | 1990 |
Chemical modulation of bleomycin induced toxicity.
Topics: Animals; Antineoplastic Agents; Bleomycin; Calmodulin; DNA Damage; Drug Synergism; In Vitro Techniqu | 1986 |
Enhanced bleomycin-induced DNA damage and cytotoxicity with calmodulin antagonists.
Topics: Animals; Bleomycin; Calmodulin; Cell Survival; Chlorpromazine; DNA; Drug Synergism; Intercellular Si | 1985 |
Differential effect of the calmodulin inhibitor trifluoperazine in modulating cellular accumulation, retention and cytotoxicity of doxorubicin in progressively doxorubicin-resistant L1210 mouse leukemia cells. Lack of correlation between cellular doxorubi
Topics: Animals; Biological Transport; Cell Survival; Doxorubicin; Drug Resistance; Female; Kinetics; Leukem | 1988 |