etidronate has been researched along with Periodontitis in 7 studies
Etidronic Acid: A diphosphonate which affects calcium metabolism. It inhibits ectopic calcification and slows down bone resorption and bone turnover.
etidronic acid : A 1,1-bis(phosphonic acid) that is (ethane-1,1-diyl)bis(phosphonic acid) having a hydroxy substituent at the 1-position. It inhibits the formation, growth, and dissolution of hydroxyapatite crystals by chemisorption to calcium phosphate surfaces.
Periodontitis: Inflammation and loss of connective tissues supporting or surrounding the teeth. This may involve any part of the PERIODONTIUM. Periodontitis is currently classified by disease progression (CHRONIC PERIODONTITIS; AGGRESSIVE PERIODONTITIS) instead of age of onset. (From 1999 International Workshop for a Classification of Periodontal Diseases and Conditions, American Academy of Periodontology)
| Excerpt | Relevance | Reference |
|---|---|---|
| "The present study was designed to evaluate the effects of risedronate, one of the most potent bisphosphonates, on alveolar bone resorption and angiogenesis in rats with experimental periodontitis to identify dose-response curves and treatment durations that can be therapeutic for periodontal therapy versus those associated with osteonecrosis of the jaws." | 1.35 | Effects of risedronate on alveolar bone loss and angiogenesis: a stereologic study in rats. ( Ayas, B; Cetinkaya, BO; Gurgor, P; Keles, GC, 2008) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (14.29) | 18.2507 |
| 2000's | 5 (71.43) | 29.6817 |
| 2010's | 1 (14.29) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Cetinkaya, BO | 1 |
| Keles, GC | 1 |
| Ayas, B | 1 |
| Gurgor, P | 1 |
| Hasegawa, T | 1 |
| Ri, S | 1 |
| Umeda, M | 1 |
| Komatsubara, H | 1 |
| Kobayashi, M | 1 |
| Shigeta, T | 1 |
| Yoshitomi, I | 1 |
| Ikeda, H | 1 |
| Shibuya, Y | 1 |
| Asahina, I | 1 |
| Komori, T | 1 |
| Tenenbaum, HC | 1 |
| Shelemay, A | 1 |
| Girard, B | 1 |
| Zohar, R | 1 |
| Fritz, PC | 1 |
| Lane, N | 1 |
| Armitage, GC | 1 |
| Loomer, P | 1 |
| Hsieh, S | 1 |
| Majumdar, S | 1 |
| Wang, HY | 1 |
| Jeffcoat, M | 1 |
| Munoz, T | 1 |
| Kolobkova, LN | 2 |
| Nikolaev, IV | 1 |
| Stepanova, EV | 1 |
| Landesman, EO | 1 |
| Koroleva, OV | 1 |
| Shoji, K | 1 |
| Horiuchi, H | 1 |
| Shinoda, H | 1 |
| Seleznev, AN | 1 |
| Petrovich, IuA | 1 |
| Kozlov, SA | 1 |
| Kachkaeva, SS | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Investigation of the Effects of Bisphosphonate on the Gingival Crevicular Fluid Levels of Sclerostin and the DKK-1 in Individuals With Postmenopausal Osteoporosis With Periodontal Changes[NCT04149405] | Phase 4 | 43 participants (Actual) | Interventional | 2016-06-30 | Completed | ||
| Effect of Periodontal Therapy and Bisphosphonates on Gingival Crevicular Fluid Levels of Nuclear Factor- κb Ligand (RANKL) and Osteoprotegerin in Postmenopausal Osteoporosis: Results of a 12-Month Study[NCT02808988] | Phase 4 | 47 participants (Actual) | Interventional | 2013-10-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
levels of dickkopf-related protein-1 in 12th month (NCT04149405)
Timeframe: 12 months
| Intervention | ng/ml (Mean) |
|---|---|
| Group A | 3440.67 |
| Group B | 3203.802 |
| Group C | 2490.553 |
| Group D | 4269.39 |
levels of dickkopf-related protein-1 in 6th month (NCT04149405)
Timeframe: 6 months
| Intervention | ng/ml (Mean) |
|---|---|
| Group A | 3358.265 |
| Group B | 1963.185 |
| Group C | 3263.665 |
| Group D | 4269.39 |
levels of sclerostin in 12th month (NCT04149405)
Timeframe: 12 month
| Intervention | ng/ml (Mean) |
|---|---|
| Group A | 1702.265 |
| Group B | 1347.330 |
| Group C | 1114.988 |
| Group D | 2131.87 |
levels of sclerostin in 6th month (NCT04149405)
Timeframe: 6 months
| Intervention | ng/ml (Mean) |
|---|---|
| Group A | 1389.177 |
| Group B | 1085.405 |
| Group C | 1596.585 |
| Group D | 2131.87 |
1 review available for etidronate and Periodontitis
| Article | Year |
|---|---|
Bisphosphonates and periodontics: potential applications for regulation of bone mass in the periodontium and other therapeutic/diagnostic uses.
Topics: Alendronate; Alveolar Bone Loss; Animals; Bone Density; Bone Regeneration; Diphosphonates; Etidronic | 2002 |
2 trials available for etidronate and Periodontitis
| Article | Year |
|---|---|
Bisphosphonate therapy improves the outcome of conventional periodontal treatment: results of a 12-month, randomized, placebo-controlled study.
Topics: Alendronate; Alveolar Bone Loss; Analysis of Variance; Chemotherapy, Adjuvant; Dental Scaling; Dipho | 2005 |
Bisphosphonate therapy improves the outcome of conventional periodontal treatment: results of a 12-month, randomized, placebo-controlled study.
Topics: Alendronate; Alveolar Bone Loss; Analysis of Variance; Chemotherapy, Adjuvant; Dental Scaling; Dipho | 2005 |
Bisphosphonate therapy improves the outcome of conventional periodontal treatment: results of a 12-month, randomized, placebo-controlled study.
Topics: Alendronate; Alveolar Bone Loss; Analysis of Variance; Chemotherapy, Adjuvant; Dental Scaling; Dipho | 2005 |
Bisphosphonate therapy improves the outcome of conventional periodontal treatment: results of a 12-month, randomized, placebo-controlled study.
Topics: Alendronate; Alveolar Bone Loss; Analysis of Variance; Chemotherapy, Adjuvant; Dental Scaling; Dipho | 2005 |
[Application of xidiphone in complex of measures for inflammatory periodontal disease prevention].
Topics: Adult; Bone Density Conservation Agents; Calcium; Etidronic Acid; Female; Humans; Hydrogen-Ion Conce | 2007 |
4 other studies available for etidronate and Periodontitis
| Article | Year |
|---|---|
Effects of risedronate on alveolar bone loss and angiogenesis: a stereologic study in rats.
Topics: Alveolar Bone Loss; Alveolar Process; Animals; Blood Vessels; Bone Density; Bone Density Conservatio | 2008 |
The observational study of delayed wound healing after tooth extraction in patients receiving oral bisphosphonate therapy.
Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Alendronate; Antibiotic Prophylaxis; Bisphosph | 2013 |
Inhibitory effects of a bisphosphonate (risedronate) on experimental periodontitis in rats.
Topics: Alveolar Bone Loss; Analysis of Variance; Animals; Bone Density; Calcium Channel Blockers; Cell Coun | 1995 |
[Pathogenetic validation of xidiphone use in combined therapy for periodontal diseases].
Topics: Acute Disease; Adolescent; Adult; Calcium; Clinical Protocols; Drug Therapy, Combination; Etidronic | 2002 |