irsogladine has been researched along with Periodontitis in 2 studies
irsogladine: RN given refers to parent cpd; MN 1695 refers to maleate salt
Periodontitis: Inflammation and loss of connective tissues supporting or surrounding the teeth. This may involve any part of the PERIODONTIUM. Periodontitis is currently classified by disease progression (CHRONIC PERIODONTITIS; AGGRESSIVE PERIODONTITIS) instead of age of onset. (From 1999 International Workshop for a Classification of Periodontal Diseases and Conditions, American Academy of Periodontology)
| Excerpt | Relevance | Reference |
|---|---|---|
| "This study aimed to investigate the potential effects of the combination therapy of irsogladine maleate (IM) and azithromycin (AZM) on the inflammation in lipopolysaccharide (LPS)-induced gingival epithelial cells." | 3.85 | A combination of irsogladine maleate and azithromycin exhibits addictive protective effects in LPS-induced human gingival epithelial cells. ( Feng, X; Liu, J, 2017) |
| "Periodontitis is an infectious inflammatory disease." | 1.39 | Irsogladine maleate regulates the inflammatory related genes in human gingival epithelial cells stimulated by Aggregatibacter actinomycetemcomitans. ( Abiko, Y; Fujita, T; Hayashida, K; Imai, H; Iwata, T; Kajiya, M; Kurihara, H; Matsuda, S; Miyagawa, T; Ouhara, K; Shiba, H; Yoshimoto, T, 2013) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Feng, X | 1 |
| Liu, J | 1 |
| Miyagawa, T | 1 |
| Fujita, T | 1 |
| Ouhara, K | 1 |
| Matsuda, S | 1 |
| Kajiya, M | 1 |
| Hayashida, K | 1 |
| Imai, H | 1 |
| Yoshimoto, T | 1 |
| Iwata, T | 1 |
| Shiba, H | 1 |
| Abiko, Y | 1 |
| Kurihara, H | 1 |
2 other studies available for irsogladine and Periodontitis
| Article | Year |
|---|---|
A combination of irsogladine maleate and azithromycin exhibits addictive protective effects in LPS-induced human gingival epithelial cells.
Topics: Anti-Bacterial Agents; Anti-Ulcer Agents; Azithromycin; Blotting, Western; Cadherins; Cell Line; Cyt | 2017 |
Irsogladine maleate regulates the inflammatory related genes in human gingival epithelial cells stimulated by Aggregatibacter actinomycetemcomitans.
Topics: Actinobacillus Infections; Aggregatibacter actinomycetemcomitans; Animals; Antigens, Bacterial; Cell | 2013 |