Page last updated: 2024-10-16

adenine and Periodontitis

adenine has been researched along with Periodontitis in 25 studies

Periodontitis: Inflammation and loss of connective tissues supporting or surrounding the teeth. This may involve any part of the PERIODONTIUM. Periodontitis is currently classified by disease progression (CHRONIC PERIODONTITIS; AGGRESSIVE PERIODONTITIS) instead of age of onset. (From 1999 International Workshop for a Classification of Periodontal Diseases and Conditions, American Academy of Periodontology)

Research Excerpts

ExcerptRelevanceReference
"This review assesses the associations of interleukin-8 gene (IL-8) -251A/T (rs4073) and -845T/C (rs2227532) polymorphisms with susceptibility to periodontitis."8.91Quantitative assessment of the associations between interleukin-8 polymorphisms and periodontitis susceptibility. ( Chen, X; Ding, C; Huang, J; Zhong, L, 2015)
"The frequency of homozygocity for the rare allele of the beta-fibrinogen gene (H2H2) was 13% for the periodontitis patients and 3% for the control group (P = 0."7.72Association of increased levels of fibrinogen and the -455G/A fibrinogen gene polymorphism with chronic periodontitis. ( De Nardin, E; Genco, RJ; Sahingur, SE; Sharma, A, 2003)
"Periodontitis is an inflammation characterized by alveolar bone resorption caused by imbalance in bone homeostasis."5.56Chloroquine and 3-Methyladenine Attenuates Periodontal Inflammation and Bone Loss in Experimental Periodontitis. ( Chen, B; He, S; Li, L; Luo, B; Yan, F; Zhou, Q, 2020)
"This review assesses the associations of interleukin-8 gene (IL-8) -251A/T (rs4073) and -845T/C (rs2227532) polymorphisms with susceptibility to periodontitis."4.91Quantitative assessment of the associations between interleukin-8 polymorphisms and periodontitis susceptibility. ( Chen, X; Ding, C; Huang, J; Zhong, L, 2015)
"The frequency of homozygocity for the rare allele of the beta-fibrinogen gene (H2H2) was 13% for the periodontitis patients and 3% for the control group (P = 0."3.72Association of increased levels of fibrinogen and the -455G/A fibrinogen gene polymorphism with chronic periodontitis. ( De Nardin, E; Genco, RJ; Sahingur, SE; Sharma, A, 2003)
"Periodontitis is a common chronic disease."1.62Syndecan 4 contributes to osteoclast differentiation induced by RANKL through enhancing autophagy. ( Han, Z; Jing, B; Li, J; Lin, Y; Sun, Z; Yan, H; Yan, Y, 2021)
"Periodontitis is an inflammation characterized by alveolar bone resorption caused by imbalance in bone homeostasis."1.56Chloroquine and 3-Methyladenine Attenuates Periodontal Inflammation and Bone Loss in Experimental Periodontitis. ( Chen, B; He, S; Li, L; Luo, B; Yan, F; Zhou, Q, 2020)
"Periodontitis was produced by a ligature placed around the cervix of the two lower first molar."1.36Increase nitric oxide synthase activity in parotid glands from rats with experimental periodontitis. ( Borda, E; Busch, L; Miozza, V; S-Borda, L, 2010)
"Periodontitis is a multifactorial disease in which environmental and genetic determinant factors contribute to individual subjects susceptibility."1.35E-selectin and L-selectin polymorphisms in patients with periodontitis. ( Gholami, L; Hajilooi, M; Houshmand, B; Mani-Kashani, K; Rafiei, A, 2009)
"Severe forms of periodontitis are suggested to have a genetic basis."1.32Association of the -1087 IL 10 gene polymorphism with severe chronic periodontitis in Swedish Caucasians. ( Berglundh, T; Donati, M; Hahn-Zoric, M; Hanson, LA; Padyukov, L, 2003)
"Periodontitis is an inflammatory disease that leads to irreversible attachment loss, bone destruction and eventually tooth loss."1.32Polymorphisms in the +252(A/G) lymphotoxin-alpha and the -308(A/G) tumor necrosis factor-alpha genes and susceptibility to chronic periodontitis in a Czech population. ( Buckova, D; Fassmann, A; Holla, LI; Vanek, J; Vasku, A; Znojil, V, 2003)

Research

Studies (25)

TimeframeStudies, this research(%)All Research%
pre-19901 (4.00)18.7374
1990's0 (0.00)18.2507
2000's12 (48.00)29.6817
2010's10 (40.00)24.3611
2020's2 (8.00)2.80

Authors

AuthorsStudies
He, S1
Zhou, Q1
Luo, B1
Chen, B1
Li, L1
Yan, F1
Li, J1
Sun, Z1
Lin, Y1
Yan, Y1
Yan, H1
Jing, B1
Han, Z1
Song, L1
Tan, J1
Wang, Z1
Ding, P1
Tang, Q1
Xia, M1
Wei, Y1
Chen, L1
Schulz, S3
Reichert, S3
Streetz, K1
Trautwein, C1
Reichert, Y2
Gläser, C3
Schaller, HG3
Stein, JM1
Ding, C2
Ji, X1
Chen, X2
Xu, Y1
Zhong, L2
Huang, J1
Machulla, HK1
Klapproth, J1
Zimmermann, U1
Nikolopoulos, GK1
Dimou, NL1
Hamodrakas, SJ1
Bagos, PG1
Houshmand, B1
Rafiei, A1
Hajilooi, M1
Mani-Kashani, K1
Gholami, L1
Chai, L1
Song, YQ1
Zee, KY1
Leung, WK1
Ozturk, A1
Famili, P1
Vieira, AR1
Miozza, V1
Borda, E1
S-Borda, L1
Busch, L1
Deng, H1
Liu, F1
Pan, Y1
Jin, X1
Wang, H1
Cao, J1
Iwanaga, R1
Sugita, N1
Hirano, E1
Sasahara, J1
Kikuchi, A1
Tanaka, K1
Yoshie, H2
Schlitt, A1
Lutze, A1
Lischewski, S1
Seifert, T1
Dudakliewa, T1
Gawe, R1
Werdan, K1
Hofmann, B1
Berglundh, T1
Donati, M1
Hahn-Zoric, M1
Hanson, LA1
Padyukov, L1
Sahingur, SE1
Sharma, A1
Genco, RJ1
De Nardin, E1
Fassmann, A1
Holla, LI1
Buckova, D1
Vasku, A1
Znojil, V1
Vanek, J1
Scarel-Caminaga, RM1
Trevilatto, PC1
Souza, AP1
Brito, RB1
Camargo, LE1
Line, SR2
Folwaczny, M1
Glas, J1
Török, HP1
Mende, M1
Folwaczny, C1
Astolfi, CM1
Shinohara, AL1
da Silva, RA1
Santos, MC1
de Souza, AP1
Galicia, JC1
Tai, H1
Komatsu, Y1
Shimada, Y1
Ikezawa, I1
Park, KS1
Nam, JH1
Choi, J1
Gonzales, JR1
Mann, M1
Stelzig, J1
Bödeker, RH1
Meyle, J1
Jahngen, EG1
Brecx, M1
Rossomando, EF1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Periodontitis and Its Microbiological Agents as Prognostic Factors in Patients With Coronary Heart Disease[NCT01045070]960 participants (Actual)Observational2009-10-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

4 reviews available for adenine and Periodontitis

ArticleYear
TNF-α gene promoter polymorphisms contribute to periodontitis susceptibility: evidence from 46 studies.
    Journal of clinical periodontology, 2014, Volume: 41, Issue:8

    Topics: Adenine; Cytosine; Genetic Predisposition to Disease; Genotype; Guanine; Humans; Periodontitis; Poly

2014
Quantitative assessment of the associations between interleukin-8 polymorphisms and periodontitis susceptibility.
    Journal of periodontology, 2015, Volume: 86, Issue:2

    Topics: Adenine; Asian People; Brazil; Cytosine; Ethnicity; Genetic Predisposition to Disease; Humans; Inter

2015
Cytokine gene polymorphisms in periodontal disease: a meta-analysis of 53 studies including 4178 cases and 4590 controls.
    Journal of clinical periodontology, 2008, Volume: 35, Issue:9

    Topics: Adenine; Alleles; Chronic Periodontitis; Cytosine; Genotype; Guanine; Humans; Interleukin-1alpha; In

2008
BsmI, TaqI, ApaI, and FokI polymorphisms in the vitamin D receptor gene and periodontitis: a meta-analysis of 15 studies including 1338 cases and 1302 controls.
    Journal of clinical periodontology, 2011, Volume: 38, Issue:3

    Topics: Adenine; Aggressive Periodontitis; Alleles; Chronic Periodontitis; Deoxyribonucleases, Type II Site-

2011

Other Studies

21 other studies available for adenine and Periodontitis

ArticleYear
Chloroquine and 3-Methyladenine Attenuates Periodontal Inflammation and Bone Loss in Experimental Periodontitis.
    Inflammation, 2020, Volume: 43, Issue:1

    Topics: Adenine; Alveolar Bone Loss; Alveolar Process; Animals; Anti-Inflammatory Agents; Autophagy; Autopha

2020
Syndecan 4 contributes to osteoclast differentiation induced by RANKL through enhancing autophagy.
    International immunopharmacology, 2021, Volume: 91

    Topics: Adenine; Animals; Autophagy; Cell Differentiation; Disease Models, Animal; Male; Mice; NF-kappa B; O

2021
Interleukin‑17A facilitates osteoclast differentiation and bone resorption via activation of autophagy in mouse bone marrow macrophages.
    Molecular medicine reports, 2019, Volume: 19, Issue:6

    Topics: Actins; Adenine; Alveolar Bone Loss; Animals; Autophagosomes; Autophagy; Bone Marrow; Bone Resorptio

2019
Tumor necrosis factor-α and oral inflammation in patients with Crohn disease.
    Journal of periodontology, 2014, Volume: 85, Issue:10

    Topics: Adenine; Adult; Age Factors; Alleles; Case-Control Studies; Crohn Disease; Female; Genetic Variation

2014
Interferon-gamma and interleukin-12 gene polymorphisms and their relation to aggressive and chronic periodontitis and key periodontal pathogens.
    Journal of periodontology, 2008, Volume: 79, Issue:8

    Topics: Adenine; Adult; Age Factors; Aggregatibacter actinomycetemcomitans; Alleles; Bacteria; Cytosine; Fem

2008
E-selectin and L-selectin polymorphisms in patients with periodontitis.
    Journal of periodontal research, 2009, Volume: 44, Issue:1

    Topics: Adenine; Adolescent; Adult; Aggressive Periodontitis; Alleles; Arginine; Chronic Periodontitis; Cyto

2009
Single nucleotide polymorphisms of complement component 5 and periodontitis.
    Journal of periodontal research, 2010, Volume: 45, Issue:3

    Topics: Adenine; Adolescent; Adult; Age Factors; Aggressive Periodontitis; Case-Control Studies; Chronic Per

2010
The antimicrobial peptide DEFB1 is associated with caries.
    Journal of dental research, 2010, Volume: 89, Issue:6

    Topics: Adenine; Adolescent; Adult; Aged; Aged, 80 and over; Aggressive Periodontitis; Alleles; Antimicrobia

2010
Increase nitric oxide synthase activity in parotid glands from rats with experimental periodontitis.
    Oral diseases, 2010, Volume: 16, Issue:8

    Topics: Adenine; Amylases; Animals; Calcium; Cyclic AMP-Dependent Protein Kinase Catalytic Subunits; Cycloox

2010
FcγRIIB polymorphisms, periodontitis and preterm birth in Japanese pregnant women.
    Journal of periodontal research, 2011, Volume: 46, Issue:3

    Topics: Adenine; Adult; Antibodies, Bacterial; Case-Control Studies; Cytosine; Exons; Female; Gestational Ag

2011
The importance of genetic variants in TNFα for periodontal disease in a cohort of coronary patients.
    Journal of clinical periodontology, 2012, Volume: 39, Issue:8

    Topics: Adenine; Aged; Alleles; Bacteria; Cohort Studies; Coronary Disease; Dental Plaque Index; Diabetes Co

2012
Association of the -1087 IL 10 gene polymorphism with severe chronic periodontitis in Swedish Caucasians.
    Journal of clinical periodontology, 2003, Volume: 30, Issue:3

    Topics: Adenine; Adult; Aged; Alleles; Alveolar Bone Loss; Chi-Square Distribution; Chronic Disease; Confide

2003
Association of increased levels of fibrinogen and the -455G/A fibrinogen gene polymorphism with chronic periodontitis.
    Journal of periodontology, 2003, Volume: 74, Issue:3

    Topics: 5' Flanking Region; Adenine; Age Factors; Aged; Alleles; Analysis of Variance; Case-Control Studies;

2003
Polymorphisms in the +252(A/G) lymphotoxin-alpha and the -308(A/G) tumor necrosis factor-alpha genes and susceptibility to chronic periodontitis in a Czech population.
    Journal of periodontal research, 2003, Volume: 38, Issue:4

    Topics: Adenine; Adult; Case-Control Studies; Chronic Disease; Czech Republic; Female; Gene Frequency; Genet

2003
Interleukin 10 gene promoter polymorphisms are associated with chronic periodontitis.
    Journal of clinical periodontology, 2004, Volume: 31, Issue:6

    Topics: Adenine; Adult; Chronic Disease; Cytosine; Female; Gene Frequency; Genetic Predisposition to Disease

2004
Lack of association between the TNF alpha G -308 A promoter polymorphism and periodontal disease.
    Journal of clinical periodontology, 2004, Volume: 31, Issue:6

    Topics: Adenine; Adult; Aged; Alleles; Chronic Disease; Female; Gene Frequency; Genetic Predisposition to Di

2004
Genetic polymorphisms in the MMP-1 and MMP-3 gene may contribute to chronic periodontitis in a Brazilian population.
    Journal of clinical periodontology, 2006, Volume: 33, Issue:10

    Topics: Adenine; Adult; Alleles; Brazil; Chronic Disease; Female; Gene Frequency; Genetic Predisposition to

2006
Interleukin-6 receptor gene polymorphisms and periodontitis in a non-smoking Japanese population.
    Journal of clinical periodontology, 2006, Volume: 33, Issue:10

    Topics: Adenine; Adult; Aged; Alanine; Alleles; Aspartic Acid; Biomarkers; Cytosine; Exons; Female; Genetic

2006
The short vitamin D receptor is associated with increased risk for generalized aggressive periodontitis.
    Journal of clinical periodontology, 2006, Volume: 33, Issue:8

    Topics: Adenine; Adult; Alveolar Bone Loss; Codon; Cytosine; Exons; Female; Gene Frequency; Genetic Predispo

2006
Single-nucleotide polymorphisms in the IL-4 and IL-13 promoter region in aggressive periodontitis.
    Journal of clinical periodontology, 2007, Volume: 34, Issue:6

    Topics: Adenine; Adult; Case-Control Studies; Cytosine; DNA; Female; Gene Frequency; Genotype; Gingival Hemo

2007
High-performance liquid chromatography analysis of purine nucleosides in human gingival crevicular fluid.
    Archives of oral biology, 1984, Volume: 29, Issue:8

    Topics: Adenine; Adenosine Monophosphate; Chromatography, High Pressure Liquid; Gingival Crevicular Fluid; G

1984