carvedilol and Periodontitis studies

Periodontitis: Inflammation and loss of connective tissues supporting or surrounding the teeth. This may involve any part of the PERIODONTIUM. Periodontitis is currently classified by disease progression (CHRONIC PERIODONTITIS; AGGRESSIVE PERIODONTITIS) instead of age of onset. (From 1999 International Workshop for a Classification of Periodontal Diseases and Conditions, American Academy of Periodontology)

Research Excerpts

Excerpt	Relevance	Reference
"Carvedilol is a β-blocker used as a multifunctional neurohormonal antagonist that has been shown to act not only as an anti-oxidant but also as an anti-inflammatory drug."	5.39	Carvedilol decrease IL-1β and TNF-α, inhibits MMP-2, MMP-9, COX-2, and RANKL expression, and up-regulates OPG in a rat model of periodontitis. ( de Araújo Júnior, RF; de Araújo, AA; de Lucena, HF; de Medeiros, CA; de Souza, LB; do Socorro Costa Feitosa Alves, M; Freitas, Mde L; Souza, TO, 2013)
"Carvedilol is a β-blocker used as a multifunctional neurohormonal antagonist that has been shown to act not only as an anti-oxidant but also as an anti-inflammatory drug."	1.39	Carvedilol decrease IL-1β and TNF-α, inhibits MMP-2, MMP-9, COX-2, and RANKL expression, and up-regulates OPG in a rat model of periodontitis. ( de Araújo Júnior, RF; de Araújo, AA; de Lucena, HF; de Medeiros, CA; de Souza, LB; do Socorro Costa Feitosa Alves, M; Freitas, Mde L; Souza, TO, 2013)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	0 (0.00)	29.6817
2010's	1 (100.00)	24.3611
2020's	0 (0.00)	2.80

carvedilol and Periodontitis

Research Excerpts

Research

Studies (1)

Authors

Other Studies

Authors	Studies
de Araújo Júnior, RF	1
Souza, TO	1
de Medeiros, CA	1
de Souza, LB	1
Freitas, Mde L	1
de Lucena, HF	1
do Socorro Costa Feitosa Alves, M	1
de Araújo, AA	1