fluorouracil has been researched along with Periodontitis in 10 studies
Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.
Periodontitis: Inflammation and loss of connective tissues supporting or surrounding the teeth. This may involve any part of the PERIODONTIUM. Periodontitis is currently classified by disease progression (CHRONIC PERIODONTITIS; AGGRESSIVE PERIODONTITIS) instead of age of onset. (From 1999 International Workshop for a Classification of Periodontal Diseases and Conditions, American Academy of Periodontology)
| Excerpt | Relevance | Reference |
|---|---|---|
| "To assess sodium alendronate as a local adjunctive therapy for treating experimental periodontitis in male rats treated with chemotherapy." | 8.31 | Sodium alendronate is an effective adjunctive therapy for treating periodontitis in male rats treated with anticancer chemotherapy. ( de Almeida, JM; Ervolino, E; Fiorin, LG; Furquim, EMA; Matheus, HR; Novaes, VCN; Oliveira, FLP; Piovezan, BR, 2023) |
| "The aim of this study was to evaluate the effects of low-level laser therapy (LLLT) and antimicrobial photodynamic therapy (aPDT) as adjuvant to mechanical treatment of experimental periodontitis (EP) in adult rats submitted to 5-fluorouracil (5-FU) chemotherapy." | 7.85 | Low-level laser and antimicrobial photodynamic therapy on experimental periodontitis in rats submitted to chemotherapy by 5-fluorouracil. ( de Almeida, JM; Ervolino, E; Ferro-Alves, ML; Garcia, VG; Longo, M; Miessi, DMJ; Novaes, VCN; Theodoro, LH, 2017) |
| "This study aimed to assess the effect of multiple sessions of a low-level laser therapy (LLLT) adjuvant to scaling and root planing (SRP) on the treatment of experimental periodontitis (EP) in rats treated with 5-fluorouracil (5-FU)." | 7.83 | Effect of low-level laser therapy as an adjuvant in the treatment of periodontitis induced in rats subjected to 5-fluorouracil chemotherapy. ( Assem, NZ; Duque, C; Ervolino, E; Ferro-Alves, ML; Garcia, VG; Longo, M; Louzada, LM; Theodoro, LH, 2016) |
| "This study aimed to evaluate the progression and treatment of experimental periodontitis (EP) in rats treated with 5-fluorouracil (5-FU)." | 7.81 | Evaluation of the progression and treatment of experimental periodontitis in rats subjected to chemotherapy with 5-fluorouracil. ( Bomfim, SR; de Almeida, JM; Ervolino, E; Garcia, VG; Longo, M; Novaes, VC; Theodoro, LH, 2015) |
| " lactis HN019 (HN019) in the development of experimental periodontitis (EP) in rats submitted to chemotherapy (5-fluorouracil [5FU])." | 4.31 | Impact of Bifidobacterium animalis subsp. lactis HN019 probiotic in the prevention of periodontitis associated with immunosuppression. ( Aparecida Chaves Furlaneto, F; Carla Wons, L; Casarin, R; da Silva Dólens, E; de Almeida Silva Levi, YL; Dos Santos Santinoni, C; Ervolino, E; Goulart de Castro, J; Gouveia Straioto, F; Gregorio, D; Henrique Félix Silva, P; Maia, LP; Pizzo Pitelli, L; Reis Messora, M, 2023) |
| "To assess sodium alendronate as a local adjunctive therapy for treating experimental periodontitis in male rats treated with chemotherapy." | 4.31 | Sodium alendronate is an effective adjunctive therapy for treating periodontitis in male rats treated with anticancer chemotherapy. ( de Almeida, JM; Ervolino, E; Fiorin, LG; Furquim, EMA; Matheus, HR; Novaes, VCN; Oliveira, FLP; Piovezan, BR, 2023) |
| "The aim of this study was to evaluate the effects of Lactobacillus reuteri applied locally or systemically with scaling and root planing (SRP) to the treatment of experimental periodontitis (EP) in rats treated with 5-fluorouracil." | 3.96 | Lactobacillus reuteri associated with scaling and root planing in the treatment of periodontitis in rats submitted to chemotherapy. ( da Rocha, TE; Dos Santos Neto, OM; Ervolino, E; Garcia, VG; Miessi, DMJ; Nuernberg, MAA; Scalet, V; Theodoro, LH, 2020) |
| "The aim of this study was to evaluate the effects of low-level laser therapy (LLLT) and antimicrobial photodynamic therapy (aPDT) as adjuvant to mechanical treatment of experimental periodontitis (EP) in adult rats submitted to 5-fluorouracil (5-FU) chemotherapy." | 3.85 | Low-level laser and antimicrobial photodynamic therapy on experimental periodontitis in rats submitted to chemotherapy by 5-fluorouracil. ( de Almeida, JM; Ervolino, E; Ferro-Alves, ML; Garcia, VG; Longo, M; Miessi, DMJ; Novaes, VCN; Theodoro, LH, 2017) |
| "This study aimed to assess the effect of multiple sessions of a low-level laser therapy (LLLT) adjuvant to scaling and root planing (SRP) on the treatment of experimental periodontitis (EP) in rats treated with 5-fluorouracil (5-FU)." | 3.83 | Effect of low-level laser therapy as an adjuvant in the treatment of periodontitis induced in rats subjected to 5-fluorouracil chemotherapy. ( Assem, NZ; Duque, C; Ervolino, E; Ferro-Alves, ML; Garcia, VG; Longo, M; Louzada, LM; Theodoro, LH, 2016) |
| "This study aimed to evaluate the progression and treatment of experimental periodontitis (EP) in rats treated with 5-fluorouracil (5-FU)." | 3.81 | Evaluation of the progression and treatment of experimental periodontitis in rats subjected to chemotherapy with 5-fluorouracil. ( Bomfim, SR; de Almeida, JM; Ervolino, E; Garcia, VG; Longo, M; Novaes, VC; Theodoro, LH, 2015) |
| "Periodontitis has been observed infrequently in bevacizumab-containing chemotherapy in clinical practice." | 1.39 | A retrospective analysis of periodontitis during bevacizumab treatment in metastatic colorectal cancer patients. ( Akiyoshi, K; Hamaguchi, T; Hosokawa, A; Iwasa, S; Kato, K; Nakajima, TE; Nishitani, H; Ogawa, K; Shimada, Y; Sugiyama, T; Ueno, T; Yamada, Y, 2013) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 5 (50.00) | 24.3611 |
| 2020's | 5 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Novaes, VCN | 3 |
| Ervolino, E | 9 |
| Fernandes, GL | 1 |
| Cunha, CP | 1 |
| Theodoro, LH | 7 |
| Garcia, VG | 6 |
| de Almeida, JM | 4 |
| Maia, LP | 1 |
| de Almeida Silva Levi, YL | 1 |
| Henrique Félix Silva, P | 1 |
| Carla Wons, L | 1 |
| Pizzo Pitelli, L | 1 |
| Goulart de Castro, J | 1 |
| da Silva Dólens, E | 1 |
| Gregorio, D | 1 |
| Gouveia Straioto, F | 1 |
| Dos Santos Santinoni, C | 1 |
| Casarin, R | 1 |
| Aparecida Chaves Furlaneto, F | 1 |
| Reis Messora, M | 1 |
| Oliveira, FLP | 1 |
| Matheus, HR | 1 |
| Piovezan, BR | 1 |
| Furquim, EMA | 1 |
| Fiorin, LG | 1 |
| Rocha, TED | 1 |
| Gomes, NA | 1 |
| Miessi, DMJ | 3 |
| Nuernberg, MAA | 2 |
| Rodrigues, JVS | 1 |
| Cardoso, JM | 1 |
| Scalet, V | 1 |
| Dos Santos Neto, OM | 1 |
| da Rocha, TE | 1 |
| Longo, M | 4 |
| Ferro-Alves, ML | 2 |
| Gouveia Garcia, V | 1 |
| Ferro Alves, ML | 1 |
| Duque, C | 2 |
| Wainwright, M | 1 |
| Novaes, VC | 1 |
| Bomfim, SR | 1 |
| Assem, NZ | 1 |
| Louzada, LM | 1 |
| Ogawa, K | 1 |
| Ueno, T | 1 |
| Kato, K | 1 |
| Nishitani, H | 1 |
| Akiyoshi, K | 1 |
| Iwasa, S | 1 |
| Nakajima, TE | 1 |
| Hamaguchi, T | 1 |
| Yamada, Y | 1 |
| Hosokawa, A | 1 |
| Sugiyama, T | 1 |
| Shimada, Y | 1 |
10 other studies available for fluorouracil and Periodontitis
| Article | Year |
|---|---|
Influence of the treatment with the antineoplastic agents 5-fluorouracil and cisplatin on the severity of experimental periodontitis in rats.
Topics: Alveolar Bone Loss; Animals; Antineoplastic Agents; Cisplatin; Fluorouracil; Male; Periodontitis; Ra | 2022 |
Impact of Bifidobacterium animalis subsp. lactis HN019 probiotic in the prevention of periodontitis associated with immunosuppression.
Topics: Animals; Bifidobacterium animalis; Fluorouracil; Immunosuppression Therapy; Male; Periodontitis; Pro | 2023 |
Sodium alendronate is an effective adjunctive therapy for treating periodontitis in male rats treated with anticancer chemotherapy.
Topics: Alendronate; Alveolar Bone Loss; Animals; Dental Scaling; Fluorouracil; Male; Osteocalcin; Periodont | 2023 |
Adjuvant effects of Saccharomyces cerevisiae in the treatment of experimental periodontitis in rats undergoing chemotherapy.
Topics: Adjuvants, Immunologic; Alveolar Bone Loss; Animals; Dental Scaling; Fluorouracil; Periodontitis; Ra | 2023 |
Lactobacillus reuteri associated with scaling and root planing in the treatment of periodontitis in rats submitted to chemotherapy.
Topics: Animals; Dental Scaling; Fluorouracil; Limosilactobacillus reuteri; Periodontitis; Rats; Root Planin | 2020 |
Low-level laser and antimicrobial photodynamic therapy on experimental periodontitis in rats submitted to chemotherapy by 5-fluorouracil.
Topics: Alveolar Bone Loss; Animals; Anti-Infective Agents; Combined Modality Therapy; Fluorouracil; Low-Lev | 2017 |
Multiple aPDT sessions on periodontitis in rats treated with chemotherapy: histomorphometrical, immunohistochemical, immunological and microbiological analyses.
Topics: Aggregatibacter actinomycetemcomitans; Alveolar Bone Loss; Animals; Dental Scaling; Disease Models, | 2019 |
Evaluation of the progression and treatment of experimental periodontitis in rats subjected to chemotherapy with 5-fluorouracil.
Topics: Alveolar Bone Loss; Animals; Dental Scaling; Disease Progression; Fluorouracil; Leukocytes; Male; Ne | 2015 |
Effect of low-level laser therapy as an adjuvant in the treatment of periodontitis induced in rats subjected to 5-fluorouracil chemotherapy.
Topics: Alveolar Bone Loss; Animals; Bacteria; Caspase 3; Combined Modality Therapy; Dental Scaling; Dinopro | 2016 |
A retrospective analysis of periodontitis during bevacizumab treatment in metastatic colorectal cancer patients.
Topics: Adult; Aged; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Beva | 2013 |