tolmetin has been researched along with Periodontitis in 5 studies
Tolmetin: A non-steroidal anti-inflammatory agent (ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL) similar in mode of action to INDOMETHACIN.
tolmetin : A monocarboxylic acid that is (1-methylpyrrol-2-yl)acetic acid substituted at position 5 on the pyrrole ring by a 4-methylbenzoyl group. Used in the form of its sodium salt dihydrate as a nonselective nonsteroidal anti-inflammatory drug.
Periodontitis: Inflammation and loss of connective tissues supporting or surrounding the teeth. This may involve any part of the PERIODONTIUM. Periodontitis is currently classified by disease progression (CHRONIC PERIODONTITIS; AGGRESSIVE PERIODONTITIS) instead of age of onset. (From 1999 International Workshop for a Classification of Periodontal Diseases and Conditions, American Academy of Periodontology)
| Excerpt | Relevance | Reference |
|---|---|---|
| "1% ketorolac tromethamine oral rinse prevented alveolar bone loss in adults with periodontitis." | 9.08 | Coordinate production of PGE2 and IL-1 beta in the gingival crevicular fluid of adults with periodontitis: its relationship to alveolar bone loss and disruption by twice daily treatment with ketorolac tromethamine oral rinse. ( Buchanan, W; Cavanaugh, PF; Doyle, MJ; Jeffcoat, MK; Meredith, MP; Reddy, MS, 1998) |
| "1% ketorolac tromethamine oral rinse prevented alveolar bone loss in adults with periodontitis." | 5.08 | Coordinate production of PGE2 and IL-1 beta in the gingival crevicular fluid of adults with periodontitis: its relationship to alveolar bone loss and disruption by twice daily treatment with ketorolac tromethamine oral rinse. ( Buchanan, W; Cavanaugh, PF; Doyle, MJ; Jeffcoat, MK; Meredith, MP; Reddy, MS, 1998) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 5 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Jeffcoat, MK | 2 |
| Reddy, MS | 2 |
| Haigh, S | 1 |
| Buchanan, W | 2 |
| Doyle, MJ | 2 |
| Meredith, MP | 2 |
| Nelson, SL | 1 |
| Goodale, MB | 1 |
| Wehmeyer, KR | 1 |
| Beliaeva, EI | 1 |
| Gerchikov, LN | 1 |
| Demina, LM | 1 |
| Zidra, SI | 1 |
| Cavanaugh, PF | 1 |
| Preshaw, PM | 1 |
| Lauffart, B | 1 |
| Brown, P | 1 |
| Zak, E | 1 |
| Heasman, PA | 1 |
| Corry, D | 1 |
| Moran, J | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Randomized, Double Blind, Placebo-Controlled, Phase IIB Trial of Ketorolac Mouth Rinse Evaluating the Effect of Cyclooxygenase Inhibition on Oropharyngeal Leukoplakia: Collaborative Study of the NCI, NIDCD and the NIDCR[NCT00001698] | Phase 2 | 57 participants | Interventional | 1998-06-30 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
3 trials available for tolmetin and Periodontitis
| Article | Year |
|---|---|
A comparison of topical ketorolac, systemic flurbiprofen, and placebo for the inhibition of bone loss in adult periodontitis.
Topics: Adult; Alveolar Bone Loss; Analysis of Variance; Anti-Inflammatory Agents, Non-Steroidal; Dental Pla | 1995 |
Coordinate production of PGE2 and IL-1 beta in the gingival crevicular fluid of adults with periodontitis: its relationship to alveolar bone loss and disruption by twice daily treatment with ketorolac tromethamine oral rinse.
Topics: Adult; Alveolar Bone Loss; Analysis of Variance; Anti-Inflammatory Agents, Non-Steroidal; Dinoprosto | 1998 |
Effects of ketorolac tromethamine mouthrinse (0.1%) on crevicular fluid prostaglandin E2 concentrations in untreated chronic periodontitis.
Topics: Adult; Aged; Analysis of Variance; Anti-Inflammatory Agents, Non-Steroidal; Chronic Disease; Dental | 1998 |
2 other studies available for tolmetin and Periodontitis
| Article | Year |
|---|---|
[The use of the analgesic preparation Ketorol in the combined treatment of pulpitis and periodontitis].
Topics: Adult; Aged; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Combined Modality Th | 1995 |
Assessment of acrylic bone cement as a local delivery vehicle for the application of non-steroidal anti-inflammatory drugs.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Bone Cements; Cells, Cultured; Delayed-Action Preparations; | 1998 |