Page last updated: 2024-12-07

perftoran

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Perftoran is a perfluorocarbon emulsion used as a blood substitute. It is a colorless, odorless, and tasteless liquid that is chemically inert and does not dissolve in water. Perftoran is synthesized by the fluorination of hydrocarbons, which replaces all of the hydrogen atoms with fluorine atoms. The resulting compound has a high oxygen-carrying capacity and can be used to transport oxygen to tissues in the body. Perftoran has been studied for its potential use in a variety of medical applications, including as a blood substitute in trauma patients, as a contrast agent in medical imaging, and as a treatment for certain types of cancer. It is important to note that Perftoran has not been approved for use in the United States, but it is available in some other countries. The compound is still under investigation for its potential benefits and risks.'

Cross-References

ID SourceID
PubMed CID121961
MeSH IDM0174883

Synonyms (5)

Synonym
99752-82-6
perftoran
DTXSID50244230
Q4359344
iyvcxlagszwaeq-uhfffaoysa-n

Research Excerpts

Effects

Perftoran is an emulsion of perfluorocarbons in a surfactant and electrolyte mixture. Perftoran has no necrolytic and antibacterial properties.

ExcerptReferenceRelevance
"Perftoran has a much smaller particle size resulting in milder adverse effects."( Perftoran (Vidaphor)-Introduction to Western Medicine.
Latson, GW, 2019
)
2.68
"Perftoran, which has been rebranded as Vidaphor for marketing in North America, is an emulsion of perfluorocarbons in a surfactant and electrolyte mixture. "( Perftoran (Vidaphor)-Introduction to Western Medicine.
Latson, GW, 2019
)
3.4
"Perftoran has no necrolytic and antibacterial properties and fails to make the terms of the 1st phase of the wound process shorter."( [The use of a perfluorocarbon emulsion in the local treatment of wounds complicated by a surgical infection].
Khomenchuk, AI; Khrupkin, VI; Moroz, VV; Pisarenko, LV, 1997
)
1.02

Pharmacokinetics

ExcerptReferenceRelevance
" With respect to pentoxifylline and ciprofloxacin, which are less hydrophilic, the effect of pharmacokinetic interference was either weaker or absent."( [Influence of perftoran on pharmacokinetics of hydrophilic drugs].
Pshenkina, NN, 2011
)
0.73

Dosage Studied

ExcerptRelevanceReference
" Application of perftoran in 20 ml/kg dosage had promoted the APP and the non-reversible ischemic nonocclusive PG damage occurrence and prophylaxis."( [Acute postoperative pancreatitis and hypertension of the pancreatic vascular system during hemorrhage in the course of the experiment].
Uzhva, VP, 1999
)
0.65
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (66)

TimeframeStudies, This Drug (%)All Drugs %
pre-19900 (0.00)18.7374
1990's10 (15.15)18.2507
2000's43 (65.15)29.6817
2010's13 (19.70)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 32.98

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be moderate demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index32.98 (24.57)
Research Supply Index4.78 (2.92)
Research Growth Index4.69 (4.65)
Search Engine Demand Index42.91 (26.88)
Search Engine Supply Index2.00 (0.95)

This Compound (32.98)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials18 (18.00%)5.53%
Reviews8 (8.00%)6.00%
Case Studies1 (1.00%)4.05%
Observational0 (0.00%)0.25%
Other73 (73.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]