mecamylamine has been researched along with Periodontitis in 2 studies
Mecamylamine: A nicotinic antagonist that is well absorbed from the gastrointestinal tract and crosses the blood-brain barrier. Mecamylamine has been used as a ganglionic blocker in treating hypertension, but, like most ganglionic blockers, is more often used now as a research tool.
Periodontitis: Inflammation and loss of connective tissues supporting or surrounding the teeth. This may involve any part of the PERIODONTIUM. Periodontitis is currently classified by disease progression (CHRONIC PERIODONTITIS; AGGRESSIVE PERIODONTITIS) instead of age of onset. (From 1999 International Workshop for a Classification of Periodontal Diseases and Conditions, American Academy of Periodontology)
| Excerpt | Relevance | Reference |
|---|---|---|
| "The results indicate that nicotine enhances susceptibility to periodontitis via nAChRs, which may act via suppressing protective immune responses through the cholinergic anti-inflammatory pathway." | 7.75 | Nicotinic acetylcholine receptor activation mediates nicotine-induced enhancement of experimental periodontitis. ( Breivik, T; Gjermo, P; Gundersen, Y; Opstad, PK; von Hörsten, S, 2009) |
| "The results indicate that nicotine enhances the susceptibility to periodontitis via nicotinic acetylcholine receptors, which may act by suppressing protective immune responses through the cholinergic anti-inflammatory pathway." | 7.75 | Nicotinic acetylcholine receptor activation mediates nicotine-induced enhancement of experimental periodontitis. ( Breivik, T; Gjermo, P; Gundersen, Y; Opstad, PK; von Hörsten, S, 2009) |
| "The results indicate that nicotine enhances susceptibility to periodontitis via nAChRs, which may act via suppressing protective immune responses through the cholinergic anti-inflammatory pathway." | 3.75 | Nicotinic acetylcholine receptor activation mediates nicotine-induced enhancement of experimental periodontitis. ( Breivik, T; Gjermo, P; Gundersen, Y; Opstad, PK; von Hörsten, S, 2009) |
| "The results indicate that nicotine enhances the susceptibility to periodontitis via nicotinic acetylcholine receptors, which may act by suppressing protective immune responses through the cholinergic anti-inflammatory pathway." | 3.75 | Nicotinic acetylcholine receptor activation mediates nicotine-induced enhancement of experimental periodontitis. ( Breivik, T; Gjermo, P; Gundersen, Y; Opstad, PK; von Hörsten, S, 2009) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Breivik, T | 2 |
| Gundersen, Y | 2 |
| Gjermo, P | 2 |
| von Hörsten, S | 2 |
| Opstad, PK | 2 |
2 other studies available for mecamylamine and Periodontitis
| Article | Year |
|---|---|
Nicotinic acetylcholine receptor activation mediates nicotine-induced enhancement of experimental periodontitis.
Topics: Alveolar Bone Loss; Animals; Corticosterone; Disease Models, Animal; Disease Susceptibility; Escheri | 2009 |
Nicotinic acetylcholine receptor activation mediates nicotine-induced enhancement of experimental periodontitis.
Topics: Alveolar Bone Loss; Animals; Corticosterone; Disease Susceptibility; Immunity; Interleukin-10; Lipop | 2009 |