Compounds > 6-bromoindirubin-3--oxime

6-bromoindirubin-3--oxime and Periodontitis

6-bromoindirubin-3--oxime has been researched along with Periodontitis* in 1 studies

Other Studies

1 other study(ies) available for 6-bromoindirubin-3--oxime and Periodontitis

ArticleYear
6-Bromoindirubin-3'-oxime Promotes Osteogenic Differentiation of Periodontal Ligament Stem Cells and Facilitates Bone Regeneration in a Mouse Periodontitis Model.
    ACS biomaterials science & engineering, 2021, 01-11, Volume: 7, Issue:1

    Effective bone tissue engineering is important to overcome the unmet clinical challenges of periodontal tissue regeneration. Successful bone tissue engineering comprises three key factors: stem cells, growth factors, and scaffolds. 6-Bromoindirubin-3'-oxime (BIO) is an inhibitor of glycogen synthase kinase-3 (GSK-3) that can activate the Wnt signaling pathway by enhancing β-catenin activity. In this study, the effects of BIO on the proliferation, migration, and osteogenic differentiation of periodontal ligament stem cells (PDLSCs) were investigated. Poly(lactic-

    Topics: Animals; Bone Regeneration; Cell Differentiation; Glycogen Synthase Kinase 3; Indoles; Mice; Osteogenesis; Oximes; Periodontal Ligament; Periodontitis; Stem Cells

2021