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nifedipine and Periodontitis

nifedipine has been researched along with Periodontitis in 10 studies

Nifedipine: A potent vasodilator agent with calcium antagonistic action. It is a useful anti-anginal agent that also lowers blood pressure.

Periodontitis: Inflammation and loss of connective tissues supporting or surrounding the teeth. This may involve any part of the PERIODONTIUM. Periodontitis is currently classified by disease progression (CHRONIC PERIODONTITIS; AGGRESSIVE PERIODONTITIS) instead of age of onset. (From 1999 International Workshop for a Classification of Periodontal Diseases and Conditions, American Academy of Periodontology)

Research Excerpts

ExcerptRelevanceReference
"Tissue samples were collected from patients with healthy periodontium (H group), adult periodontitis (P group), surgically extracted teeth (S group), and nifedipine-induced gingival overgrowth (NIGO group)."7.72Immunohistochemical analysis of Th1/Th2 cytokine profiles and androgen receptor expression in the pathogenesis of nifedipine-induced gingival overgrowth. ( Chou, HH; Huang, WT; Kuo, MY; Lu, HK, 2003)
"Periodontitis was induced by oral inoculation with Porphyromonas gingivalis over a 3-week time period."5.91Nifedipine attenuates alveolar bone destruction and improves trabecular microarchitectures in mice with experimental periodontitis. ( Choi, EY; Choi, IS; Kim, SJ; Lee, AR; Lee, JE; Lee, Y, 2023)
"Nifedipine alone was not sufficient to promote gingival enlargement or periodontal destruction in the absence of the ligature."5.36Effect of nifedipine on gingival enlargement and periodontal breakdown in ligature-induced periodontitis in rats. ( Fernandes, MI; Gaio, EJ; Oppermann, RV; Rados, PV; Rösing, CK; Susin, C, 2010)
"The hypothesis that nifedipine-induced gingival enlargement in periodontitis patients can be treated with the adjunctive use of tetracycline (TCN) fibers was tested in this study."3.73Tetracycline fibers as an adjunct in the treatment of nifedipine-induced gingival enlargement. ( Aristodemou, E; Goodson, M; Konstantinidis, AB; Sakellari, D; Socransky, S; Vouros, ID, 2005)
"Tissue samples were collected from patients with healthy periodontium (H group), adult periodontitis (P group), surgically extracted teeth (S group), and nifedipine-induced gingival overgrowth (NIGO group)."3.72Immunohistochemical analysis of Th1/Th2 cytokine profiles and androgen receptor expression in the pathogenesis of nifedipine-induced gingival overgrowth. ( Chou, HH; Huang, WT; Kuo, MY; Lu, HK, 2003)
"Periodontitis was induced by oral inoculation with Porphyromonas gingivalis over a 3-week time period."1.91Nifedipine attenuates alveolar bone destruction and improves trabecular microarchitectures in mice with experimental periodontitis. ( Choi, EY; Choi, IS; Kim, SJ; Lee, AR; Lee, JE; Lee, Y, 2023)
"Nifedipine alone was not sufficient to promote gingival enlargement or periodontal destruction in the absence of the ligature."1.36Effect of nifedipine on gingival enlargement and periodontal breakdown in ligature-induced periodontitis in rats. ( Fernandes, MI; Gaio, EJ; Oppermann, RV; Rados, PV; Rösing, CK; Susin, C, 2010)
"Drug-induced gingival overgrowth is an iatrogenic clinical condition, which affects a proportion of patients medicated for conditions such as hypertension, epilepsy and the prevention of organ transplant rejection."1.31Drug-induced gingival overgrowth: a case with auto-correction of incisor drifting. ( Butterworth, C; Chapple, I, 2001)

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's4 (40.00)18.2507
2000's3 (30.00)29.6817
2010's2 (20.00)24.3611
2020's1 (10.00)2.80

Authors

AuthorsStudies
Lee, Y1
Lee, JE1
Lee, AR1
Choi, EY1
Choi, IS1
Kim, SJ1
Fernandes, MI1
Gaio, EJ1
Susin, C1
Rösing, CK1
Oppermann, RV1
Rados, PV1
Shimizu, T1
Kubota, T1
Nakasone, N1
Abe, D1
Morozumi, T1
Yoshie, H1
Huang, WT1
Lu, HK1
Chou, HH1
Kuo, MY1
Sakellari, D1
Vouros, ID1
Aristodemou, E1
Konstantinidis, AB1
Socransky, S1
Goodson, M1
Hapak, L1
Deen-Duggins, L1
Fry, HR1
Clay, JR1
Turner, JR1
Slezák, R1
Butterworth, C1
Chapple, I1
Hancock, RH1
Swan, RH1

Reviews

3 reviews available for nifedipine and Periodontitis

ArticleYear
Periodontal management of nifedipine-induced gingival overgrowth: a case report and review of the pertinent literature.
    Oral health, 1994, Volume: 84, Issue:10

    Topics: Calcium Channel Blockers; Gingival Hyperplasia; Humans; Male; Middle Aged; Nifedipine; Periodontitis

1994
Nifedipine-associated gingival overgrowth: a survey of the literature and report of four cases.
    Quintessence international (Berlin, Germany : 1985), 1996, Volume: 27, Issue:3

    Topics: Adult; Aged; Calcium Channel Blockers; Female; Gingival Hyperplasia; Humans; Male; Middle Aged; Nife

1996
Drug-induced gingival overgrowth after phenytoin and nifedipine therapy. A case report.
    The Journal of the Western Society of Periodontology/Periodontal abstracts, 1997, Volume: 45, Issue:4

    Topics: Anticonvulsants; Calcium Channel Blockers; Drug Therapy, Combination; Female; Gingival Overgrowth; H

1997

Other Studies

7 other studies available for nifedipine and Periodontitis

ArticleYear
Nifedipine attenuates alveolar bone destruction and improves trabecular microarchitectures in mice with experimental periodontitis.
    Naunyn-Schmiedeberg's archives of pharmacology, 2023, Volume: 396, Issue:12

    Topics: Alveolar Bone Loss; Animals; Disease Models, Animal; Mice; Nifedipine; Periodontitis; Porphyromonas

2023
Effect of nifedipine on gingival enlargement and periodontal breakdown in ligature-induced periodontitis in rats.
    Archives of oral biology, 2010, Volume: 55, Issue:7

    Topics: Alveolar Bone Loss; Alveolar Process; Animals; Calcium Channel Blockers; Connective Tissue; Cotton F

2010
Microarray and quantitative RT-PCR analyses in calcium-channel blockers induced gingival overgrowth tissues of periodontitis patients.
    Archives of oral biology, 2011, Volume: 56, Issue:3

    Topics: Aged; Amlodipine; Calcium Channel Blockers; Case-Control Studies; Cathepsin L; Cluster Analysis; Fem

2011
Immunohistochemical analysis of Th1/Th2 cytokine profiles and androgen receptor expression in the pathogenesis of nifedipine-induced gingival overgrowth.
    Journal of periodontal research, 2003, Volume: 38, Issue:4

    Topics: Adult; Calcium Channel Blockers; Cell Nucleus; Connective Tissue; Female; Fibroblasts; Gingival Over

2003
Tetracycline fibers as an adjunct in the treatment of nifedipine-induced gingival enlargement.
    Journal of periodontology, 2005, Volume: 76, Issue:6

    Topics: Aged; Analysis of Variance; Anti-Bacterial Agents; Calcium Channel Blockers; Gingival Overgrowth; Hu

2005
Drug-induced gingival overgrowth: a case with auto-correction of incisor drifting.
    Dental update, 2001, Volume: 28, Issue:8

    Topics: Calcium Channel Blockers; Gingival Overgrowth; Humans; Incisor; Kidney Transplantation; Male; Middle

2001
Nifedipine-induced gingival overgrowth. Report of a case treated by controlling plaque.
    Journal of clinical periodontology, 1992, Volume: 19, Issue:1

    Topics: Dental Calculus; Dental Plaque; Dental Scaling; Gingival Hyperplasia; Humans; Male; Middle Aged; Nif

1992