cimetidine has been researched along with Periodontitis in 3 studies
Cimetidine: A histamine congener, it competitively inhibits HISTAMINE binding to HISTAMINE H2 RECEPTORS. Cimetidine has a range of pharmacological actions. It inhibits GASTRIC ACID secretion, as well as PEPSIN and GASTRIN output.
cimetidine : A member of the class of guanidines that consists of guanidine carrying a methyl substituent at position 1, a cyano group at position 2 and a 2-{[(5-methyl-1H-imidazol-4-yl)methyl]sulfanyl}ethyl group at position 3. It is a H2-receptor antagonist that inhibits the production of acid in stomach.
Periodontitis: Inflammation and loss of connective tissues supporting or surrounding the teeth. This may involve any part of the PERIODONTIUM. Periodontitis is currently classified by disease progression (CHRONIC PERIODONTITIS; AGGRESSIVE PERIODONTITIS) instead of age of onset. (From 1999 International Workshop for a Classification of Periodontal Diseases and Conditions, American Academy of Periodontology)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Cimetidine is a powerful H2 receptor antagonist that eliminates histamine's effects on chemotaxis, phagocytosis, and superoxide anion production by phagocytes." | 1.33 | Topical H2 antagonist prevents periodontitis in a rabbit model. ( Andry, C; Ebrahimi, N; Hasturk, H; Holick, M; Jones, VL; Kantarci, A; Van Dyke, TE, 2006) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (66.67) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Longhini, R | 1 |
| Aparecida de Oliveira, P | 1 |
| Sasso-Cerri, E | 1 |
| Cerri, PS | 1 |
| Van Dyke, TE | 2 |
| Cutler, CW | 1 |
| Kowolik, M | 1 |
| Singer, RS | 1 |
| Buchanan, W | 1 |
| Biesbrock, AR | 1 |
| Hasturk, H | 1 |
| Kantarci, A | 1 |
| Ebrahimi, N | 1 |
| Andry, C | 1 |
| Holick, M | 1 |
| Jones, VL | 1 |
1 trial available for cimetidine and Periodontitis
| Article | Year |
|---|---|
Effect of topical cimetidine rinse on gingival crevicular neutrophil leukocyte function.
Topics: Adjuvants, Immunologic; Adolescent; Adult; Cimetidine; Cross-Over Studies; Double-Blind Method; Ging | 2005 |
2 other studies available for cimetidine and Periodontitis
| Article | Year |
|---|---|
Cimetidine reduces alveolar bone loss in induced periodontitis in rat molars.
Topics: Acid Phosphatase; Alveolar Bone Loss; Alveolar Process; Animals; Cimetidine; Coloring Agents; Connec | 2014 |
Topical H2 antagonist prevents periodontitis in a rabbit model.
Topics: Administration, Topical; Animals; Bacteroidaceae Infections; Cimetidine; Disease Models, Animal; Dos | 2006 |