Page last updated: 2024-11-13
neurostatin
Description
Research Excerpts
Clinical Trials
Roles
Classes
Pathways
Study Profile
Bioassays
Related Drugs
Related Conditions
Protein Interactions
Research Growth
Market Indicators
Description
neurostatin: from rat and bovine brain extracts; inhibits proliferation of cultured astrocytes [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]
Cross-References
ID Source | ID |
---|---|
PubMed CID | 71716390 |
CHEMBL ID | 2333157 |
MeSH ID | M0298550 |
Synonyms (2)
Synonym |
---|
neurostatin |
CHEMBL2333157 |
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
Bioassays (5)
Assay ID | Title | Year | Journal | Article |
---|---|---|---|---|
AID734902 | Antiproliferative activity against human U377-MG cells assessed as Human epsilon 14-3-3 protein gene repression at IC50 concentration after 24 hrs by microarray analysis relative to control | 2013 | Bioorganic & medicinal chemistry letters, Jan-15, Volume: 23, Issue:2 | Synthetic glycolipids for glioma growth inhibition developed from neurostatin and NF115 compound. |
AID734904 | Antiproliferative activity against human U377-MG cells assessed as Rho GDP dissociation inhibitor (GDI) alpha gene repression at IC50 concentration after 24 hrs by microarray analysis relative to control | 2013 | Bioorganic & medicinal chemistry letters, Jan-15, Volume: 23, Issue:2 | Synthetic glycolipids for glioma growth inhibition developed from neurostatin and NF115 compound. |
AID734900 | Antiproliferative activity against human U377-MG cells assessed as Human Bcl-x beta gene repression at IC50 concentration after 24 hrs by microarray analysis relative to control | 2013 | Bioorganic & medicinal chemistry letters, Jan-15, Volume: 23, Issue:2 | Synthetic glycolipids for glioma growth inhibition developed from neurostatin and NF115 compound. |
AID734903 | Antiproliferative activity against human U377-MG cells assessed as Solute carrier family 4, anion exchanger, member 2 (erythrocyte membrane protein band 3-like 1) gene repression at IC50 concentration after 24 hrs by microarray analysis relative to contro | 2013 | Bioorganic & medicinal chemistry letters, Jan-15, Volume: 23, Issue:2 | Synthetic glycolipids for glioma growth inhibition developed from neurostatin and NF115 compound. |
AID734901 | Antiproliferative activity against human U377-MG cells assessed as Tumor protein p53 gene repression at IC50 concentration after 24 hrs by microarray analysis relative to control | 2013 | Bioorganic & medicinal chemistry letters, Jan-15, Volume: 23, Issue:2 | Synthetic glycolipids for glioma growth inhibition developed from neurostatin and NF115 compound. |
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] |
Research
Studies (13)
Timeframe | Studies, This Drug (%) | All Drugs % |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 1 (7.69) | 18.2507 |
2000's | 3 (23.08) | 29.6817 |
2010's | 9 (69.23) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] |
Market Indicators
Research Demand Index: 29.32
According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be moderate demand-to-supply ratio for research on this compound.
| This Compound (29.32) All Compounds (24.57) |
Study Types
Publication Type | This drug (%) | All Drugs (%) |
---|---|---|
Trials | 0 (0.00%) | 5.53% |
Reviews | 2 (15.38%) | 6.00% |
Case Studies | 0 (0.00%) | 4.05% |
Observational | 0 (0.00%) | 0.25% |
Other | 11 (84.62%) | 84.16% |
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] |