Page last updated: 2024-11-13

neurostatin

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

neurostatin: from rat and bovine brain extracts; inhibits proliferation of cultured astrocytes [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID71716390
CHEMBL ID2333157
MeSH IDM0298550

Synonyms (2)

Synonym
neurostatin
CHEMBL2333157
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Bioassays (5)

Assay IDTitleYearJournalArticle
AID734902Antiproliferative activity against human U377-MG cells assessed as Human epsilon 14-3-3 protein gene repression at IC50 concentration after 24 hrs by microarray analysis relative to control2013Bioorganic & medicinal chemistry letters, Jan-15, Volume: 23, Issue:2
Synthetic glycolipids for glioma growth inhibition developed from neurostatin and NF115 compound.
AID734904Antiproliferative activity against human U377-MG cells assessed as Rho GDP dissociation inhibitor (GDI) alpha gene repression at IC50 concentration after 24 hrs by microarray analysis relative to control2013Bioorganic & medicinal chemistry letters, Jan-15, Volume: 23, Issue:2
Synthetic glycolipids for glioma growth inhibition developed from neurostatin and NF115 compound.
AID734900Antiproliferative activity against human U377-MG cells assessed as Human Bcl-x beta gene repression at IC50 concentration after 24 hrs by microarray analysis relative to control2013Bioorganic & medicinal chemistry letters, Jan-15, Volume: 23, Issue:2
Synthetic glycolipids for glioma growth inhibition developed from neurostatin and NF115 compound.
AID734903Antiproliferative activity against human U377-MG cells assessed as Solute carrier family 4, anion exchanger, member 2 (erythrocyte membrane protein band 3-like 1) gene repression at IC50 concentration after 24 hrs by microarray analysis relative to contro2013Bioorganic & medicinal chemistry letters, Jan-15, Volume: 23, Issue:2
Synthetic glycolipids for glioma growth inhibition developed from neurostatin and NF115 compound.
AID734901Antiproliferative activity against human U377-MG cells assessed as Tumor protein p53 gene repression at IC50 concentration after 24 hrs by microarray analysis relative to control2013Bioorganic & medicinal chemistry letters, Jan-15, Volume: 23, Issue:2
Synthetic glycolipids for glioma growth inhibition developed from neurostatin and NF115 compound.
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (13)

TimeframeStudies, This Drug (%)All Drugs %
pre-19900 (0.00)18.7374
1990's1 (7.69)18.2507
2000's3 (23.08)29.6817
2010's9 (69.23)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 29.32

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be moderate demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index29.32 (24.57)
Research Supply Index2.64 (2.92)
Research Growth Index4.77 (4.65)
Search Engine Demand Index34.37 (26.88)
Search Engine Supply Index2.00 (0.95)

This Compound (29.32)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews2 (15.38%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other11 (84.62%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]