| Assay ID | Title | Year | Journal | Article |
|---|
| AID761496 | Inhibition of cathepsin B (unknown origin) at 6.3 uM after 20 mins by fluorometric analysis | 2013 | Bioorganic & medicinal chemistry letters, Aug-01, Volume: 23, Issue:15
| Vialinin A is a ubiquitin-specific peptidase inhibitor. |
| AID761508 | Inhibition of human USP4 using Ub-AMC as substrate after 60 mins by fluorometric analysis | 2013 | Bioorganic & medicinal chemistry letters, Aug-01, Volume: 23, Issue:15
| Vialinin A is a ubiquitin-specific peptidase inhibitor. |
| AID654111 | Antiinflammatory activity in rat RBL2H3 cells assessed as inhibition of DNP-BSA-induced TNF-alpha production preincubated for 15 mins prior DNP-BSA challenge measured after 30 mins by ELISA | 2012 | Bioorganic & medicinal chemistry letters, Apr-01, Volume: 22, Issue:7
| Design and synthesis of a vialinin A analog with a potent inhibitory activity of TNF-α production and its transformation into a couple of bioprobes. |
| AID1126481 | Inhibition of DNP-BSA-stimulated TNF-alpha production in rat RBL2H3 cells preincubated for 15 mins followed by DNP-BSA addition measured after 3 hrs by ELISA | 2014 | Bioorganic & medicinal chemistry, Apr-15, Volume: 22, Issue:8
| Structural elucidation and synthesis of vialinin C, a new inhibitor of TNF-α production. |
| AID761515 | Competitive binding affinity to human USP5 C335A mutant by SDS-PAGE analysis in presence of biotin-DMT | 2013 | Bioorganic & medicinal chemistry letters, Aug-01, Volume: 23, Issue:15
| Vialinin A is a ubiquitin-specific peptidase inhibitor. |
| AID1637032 | Inhibition of SENP1 in human KU812 cells preincubated for 20 mins followed by addition of HA-SUMO1-VS as substrate measured after 2 hrs by immunoblot analysis | 2016 | Bioorganic & medicinal chemistry letters, 09-01, Volume: 26, Issue:17
| Vialinin A and thelephantin G, potent inhibitors of tumor necrosis factor-α production, inhibit sentrin/SUMO-specific protease 1 enzymatic activity. |
| AID654112 | Antioxidant activity assessed as DPPH radical scavenging activity after 30 mins by spectrophotometry | 2012 | Bioorganic & medicinal chemistry letters, Apr-01, Volume: 22, Issue:7
| Design and synthesis of a vialinin A analog with a potent inhibitory activity of TNF-α production and its transformation into a couple of bioprobes. |
| AID1637027 | Inhibition of TNF-alpha production in mouse bone marrow-derived mast cells measured after 15 mins by ELISA | 2016 | Bioorganic & medicinal chemistry letters, 09-01, Volume: 26, Issue:17
| Vialinin A and thelephantin G, potent inhibitors of tumor necrosis factor-α production, inhibit sentrin/SUMO-specific protease 1 enzymatic activity. |
| AID761504 | Inhibition of human USP2 using Ub-AMC as substrate at 1 to 30 uM after 60 mins by fluorometric analysis | 2013 | Bioorganic & medicinal chemistry letters, Aug-01, Volume: 23, Issue:15
| Vialinin A is a ubiquitin-specific peptidase inhibitor. |
| AID1637030 | Binding affinity to recombinant human 6His-tagged SENP1 catalytic domain expressed in Escherichia coli | 2016 | Bioorganic & medicinal chemistry letters, 09-01, Volume: 26, Issue:17
| Vialinin A and thelephantin G, potent inhibitors of tumor necrosis factor-α production, inhibit sentrin/SUMO-specific protease 1 enzymatic activity. |
| AID761509 | Inhibition of wild type human USP5 expressed in Escherichia coli BL21(DE3) using Ub-AMC as substrate after 60 mins by fluorometric analysis | 2013 | Bioorganic & medicinal chemistry letters, Aug-01, Volume: 23, Issue:15
| Vialinin A is a ubiquitin-specific peptidase inhibitor. |
| AID761503 | Inhibition of human USP8 using Ub-AMC as substrate at 1 to 30 uM after 60 mins by fluorometric analysis | 2013 | Bioorganic & medicinal chemistry letters, Aug-01, Volume: 23, Issue:15
| Vialinin A is a ubiquitin-specific peptidase inhibitor. |
| AID1637031 | Binding affinity to full-length recombinant human 6His-tagged SENP1 expressed in Escherichia coli BL21 (DE3) | 2016 | Bioorganic & medicinal chemistry letters, 09-01, Volume: 26, Issue:17
| Vialinin A and thelephantin G, potent inhibitors of tumor necrosis factor-α production, inhibit sentrin/SUMO-specific protease 1 enzymatic activity. |
| AID761513 | Competitive binding affinity to human USP5 C335A/H818A mutant by SDS-PAGE analysis in presence of biotin-DMT | 2013 | Bioorganic & medicinal chemistry letters, Aug-01, Volume: 23, Issue:15
| Vialinin A is a ubiquitin-specific peptidase inhibitor. |
| AID761512 | Inhibition of wild type human USP5 expressed in Escherichia coli BL21(DE3) using K48-linked tetraubiquitin as substrate assessed as substrate hydrolysis at 10 uM after 15 mins by SDS-PAGE analysis | 2013 | Bioorganic & medicinal chemistry letters, Aug-01, Volume: 23, Issue:15
| Vialinin A is a ubiquitin-specific peptidase inhibitor. |
| AID761497 | Inhibition of calpain1/2 (unknown origin) using Suc-LLVY-AMC as substrate at 6.3 uM after 20 mins by fluorometric analysis | 2013 | Bioorganic & medicinal chemistry letters, Aug-01, Volume: 23, Issue:15
| Vialinin A is a ubiquitin-specific peptidase inhibitor. |
| AID761507 | Competitive inhibition of wild type human USP5 expressed in Escherichia coli BL21(DE3) using Ub-AMC as substrate | 2013 | Bioorganic & medicinal chemistry letters, Aug-01, Volume: 23, Issue:15
| Vialinin A is a ubiquitin-specific peptidase inhibitor. |
| AID761520 | Inhibition of TNF-alpha production in rat RBL2H3 cells after 16 hrs by ELISA | 2013 | Bioorganic & medicinal chemistry letters, Aug-01, Volume: 23, Issue:15
| Vialinin A is a ubiquitin-specific peptidase inhibitor. |
| AID1851299 | Inhibition of TNF-alpha production in rat RBL-2H3 cells | 2022 | Bioorganic & medicinal chemistry, 09-15, Volume: 70 | Anti-inflammatory and anticancer p-terphenyl derivatives from fungi of the genus Thelephora. |
| AID1637026 | Inhibition of TNF-alpha production in antigen-stimulated rat RBL2H3 cells measured after 15 mins by ELISA | 2016 | Bioorganic & medicinal chemistry letters, 09-01, Volume: 26, Issue:17
| Vialinin A and thelephantin G, potent inhibitors of tumor necrosis factor-α production, inhibit sentrin/SUMO-specific protease 1 enzymatic activity. |
| AID1637028 | Inhibition of recombinant human 6His-tagged SENP1 catalytic domain expressed in Escherichia coli preincubated for 15 mins followed by addition of SUMO1-AMC as substrate measured after 1 hr by fluorescence analysis | 2016 | Bioorganic & medicinal chemistry letters, 09-01, Volume: 26, Issue:17
| Vialinin A and thelephantin G, potent inhibitors of tumor necrosis factor-α production, inhibit sentrin/SUMO-specific protease 1 enzymatic activity. |
| AID1637029 | Inhibition of full-length recombinant human 6His-tagged SENP1 expressed in Escherichia coli BL21 (DE3) preincubated for 15 mins followed by addition of SUMO1-AMC as substrate measured after 1 hr by fluorescence analysis | 2016 | Bioorganic & medicinal chemistry letters, 09-01, Volume: 26, Issue:17
| Vialinin A and thelephantin G, potent inhibitors of tumor necrosis factor-α production, inhibit sentrin/SUMO-specific protease 1 enzymatic activity. |
| AID1851302 | Antiproliferative activity against human HepG2 cells assessed as cell growth inhibition measured after 48 hrs | 2022 | Bioorganic & medicinal chemistry, 09-15, Volume: 70 | Anti-inflammatory and anticancer p-terphenyl derivatives from fungi of the genus Thelephora. |
| AID761505 | Inhibition of human UCH-L1 using Ub-AMC as substrate after 60 mins by fluorometric analysis | 2013 | Bioorganic & medicinal chemistry letters, Aug-01, Volume: 23, Issue:15
| Vialinin A is a ubiquitin-specific peptidase inhibitor. |
| AID761506 | Inhibition of human UCH-L3 using Ub-AMC as substrate at 1 to 30 uM after 60 mins by fluorometric analysis | 2013 | Bioorganic & medicinal chemistry letters, Aug-01, Volume: 23, Issue:15
| Vialinin A is a ubiquitin-specific peptidase inhibitor. |
| AID1126480 | Inhibition of TNF-alpha production in rat RBL2H3 cells | 2014 | Bioorganic & medicinal chemistry, Apr-15, Volume: 22, Issue:8
| Structural elucidation and synthesis of vialinin C, a new inhibitor of TNF-α production. |
| AID761516 | Competitive binding affinity to human recombinant USP5 after 1 hr by SDS-PAGE analysis in presence of biotin-DMT | 2013 | Bioorganic & medicinal chemistry letters, Aug-01, Volume: 23, Issue:15
| Vialinin A is a ubiquitin-specific peptidase inhibitor. |
| AID761514 | Competitive binding affinity to human USP5 H818A mutant by SDS-PAGE analysis in presence of biotin-DMT | 2013 | Bioorganic & medicinal chemistry letters, Aug-01, Volume: 23, Issue:15
| Vialinin A is a ubiquitin-specific peptidase inhibitor. |
| AID761519 | Binding affinity to USP5 in rat RBL2H3 cell extracts at 10 to 40 uM by SDS-PAGE analysis | 2013 | Bioorganic & medicinal chemistry letters, Aug-01, Volume: 23, Issue:15
| Vialinin A is a ubiquitin-specific peptidase inhibitor. |
| [information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] |