Compounds > epsilon-hydroxynorleucine, (l)-isomer
Page last updated: 2024-11-07

epsilon-hydroxynorleucine, (l)-isomer

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

epsilon-hydroxynorleucine: RN given refers to cpd with unspecified isomeric designation [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID97725
CHEMBL ID1233976
SCHEMBL ID128663
MeSH IDM0307625

Synonyms (44)

Synonym
CHEMBL1233976
nsc-16535
6-hydroxynorleucine
epsilon-hydroxynorleucine
l-norleucine, 6-hydroxy-
nsc-206290
6033-32-5
l-2-amino-6-hydroxyhexanoic acid
NCGC00013214
6-hydroxy-l-norleucine
alpha-amino-epsilon-hydroxycaproic acid
2-amino-6-hydroxycaproic acid
DB03412
NCI16535
NCISTRUC1_001900
NCISTRUC2_000242
NCGC00096335-01
l-6-hydroxynorleucine
(2s)-2-amino-6-hydroxyhexanoic acid
AKOS006275214
nsc 16535
nsc 206290
874d12o72w ,
unii-874d12o72w
(s)-2-amino-6-hydroxyhexanoic acid
epsilon-hydroxy-l-norleucine
nsc 32041
CCG-37660
NCGC00013214-02
SCHEMBL128663
(s)-2-amino-6-hydroxy-hexanoic acid
OLUWXTFAPJJWPL-YFKPBYRVSA-N
mfcd00211279
l-6-hydroxynorleucine (h-l-nle(oh)-oh)
(+)-l-.epsilon.-hydroxynorleucine
l-6-hydroxy norleucine
CS-0266479
Q27096308
A917885
F79797
(s)-2-amino-6-hydroxyhexanoicacid
EN300-222084
PD007011
dl-6-hydroxynorleucine
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (9)

TimeframeStudies, This Drug (%)All Drugs %
pre-19906 (66.67)18.7374
1990's1 (11.11)18.2507
2000's1 (11.11)29.6817
2010's1 (11.11)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 12.05

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index12.05 (24.57)
Research Supply Index2.30 (2.92)
Research Growth Index4.36 (4.65)
Search Engine Demand Index0.00 (26.88)
Search Engine Supply Index0.00 (0.95)

This Compound (12.05)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other9 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
SubstanceRelationship StrengthStudiesTrialsClassesRoles
carbamates
[no description available]		2.0210amino-acid anion
hydroxyproline
Hydroxyproline: A hydroxylated form of the imino acid proline. A deficiency in ASCORBIC ACID can result in impaired hydroxyproline formation.. hydroxyproline : A proline derivative that is proline substituted by at least one hydroxy group.		2.36204-hydroxyproline;
L-alpha-amino acid zwitterion		human metabolite;
mouse metabolite;
plant metabolite
lysine
Lysine: An essential amino acid. It is often added to animal feed.. lysine : A diamino acid that is caproic (hexanoic) acid bearing two amino substituents at positions 2 and 6.. L-lysine : An L-alpha-amino acid; the L-isomer of lysine.		2.8540aspartate family amino acid;
L-alpha-amino acid zwitterion;
L-alpha-amino acid;
lysine;
organic molecular entity;
proteinogenic amino acid		algal metabolite;
anticonvulsant;
Escherichia coli metabolite;
human metabolite;
micronutrient;
mouse metabolite;
nutraceutical;
plant metabolite;
Saccharomyces cerevisiae metabolite
leucine
Leucine: An essential branched-chain amino acid important for hemoglobin formation.. leucine : A branched-chain amino acid that consists of glycine in which one of the hydrogens attached to the alpha-carbon is substituted by an isobutyl group.		1.9310amino acid zwitterion;
L-alpha-amino acid;
leucine;
proteinogenic amino acid;
pyruvate family amino acid		algal metabolite;
Escherichia coli metabolite;
human metabolite;
mouse metabolite;
plant metabolite;
Saccharomyces cerevisiae metabolite
6-hydroxyhexanoic acid
[no description available]		1.92106-hydroxy monocarboxylic acid;
omega-hydroxy-medium-chain fatty acid;
straight-chain fatty acid		bacterial xenobiotic metabolite
norleucine
Norleucine: An unnatural amino acid that is used experimentally to study protein structure and function. It is structurally similar to METHIONINE, however it does not contain SULFUR.. L-norleucine : A non-proteinogenic L-alpha-amino acid comprising hexanoic acid carrying an amino group at C-2. It does not occur naturally.		3.56902-aminohexanoic acid;
L-alpha-amino acid zwitterion;
non-proteinogenic L-alpha-amino acid
proline
Proline: A non-essential amino acid that is synthesized from GLUTAMIC ACID. It is an essential component of COLLAGEN and is important for proper functioning of joints and tendons.. proline : An alpha-amino acid that is pyrrolidine bearing a carboxy substituent at position 2.		1.9510amino acid zwitterion;
glutamine family amino acid;
L-alpha-amino acid;
proline;
proteinogenic amino acid		algal metabolite;
compatible osmolytes;
Escherichia coli metabolite;
micronutrient;
mouse metabolite;
nutraceutical;
Saccharomyces cerevisiae metabolite
elastin
[no description available]		1.9610oligopeptide
hydroxylysine
Hydroxylysine: A hydroxylated derivative of the amino acid LYSINE that is present in certain collagens.. hydroxylysine : A hydroxy-amino acid in which the amino acid specified is lysine. A "closed" class.. erythro-5-hydroxy-L-lysine : A 5-hydroxylysine consisting of L-lysine having an (R)-hydroxy group at the 5-position.. 5-hydroxylysine : A hydroxylysine that is lysine substituted by a hydroxy group at position 5.		1.95105-hydroxylysine;
hydroxy-L-lysine		human metabolite
nad
NAD(1-) : An anionic form of nicotinamide adenine dinucleotide arising from deprotonation of the two OH groups of the diphosphate moiety.		210organophosphate oxoanioncofactor;
human metabolite;
hydrogen acceptor;
Saccharomyces cerevisiae metabolite
desmosine
Desmosine: A rare amino acid found in elastin, formed by condensation of four molecules of lysine into a pyridinium ring.		1.9610aromatic amino acid
ConditionIndicatedRelationship StrengthStudiesTrials
B-Cell Lymphoma
[description not available]		02.0710
Lymphoma, B-Cell
A group of heterogeneous lymphoid tumors generally expressing one or more B-cell antigens or representing malignant transformations of B-lymphocytes.		02.0710
Arteriosclerosis
Thickening and loss of elasticity of the walls of ARTERIES of all sizes. There are many forms classified by the types of lesions and arteries involved, such as ATHEROSCLEROSIS with fatty lesions in the ARTERIAL INTIMA of medium and large muscular arteries.		02.0210
Alcoholic Cirrhosis
[description not available]		01.9510
Liver Cirrhosis, Alcoholic
FIBROSIS of the hepatic parenchyma due to chronic excess ALCOHOL DRINKING.		01.9510
Cicatrization
The formation of fibrous tissue in the place of normal tissue during the process of WOUND HEALING. It includes scar tissue formation occurring in healing internal organs as well as in the skin after surface injuries.		01.9610
Cardiovascular Stroke
[description not available]		01.9610
Cicatrix
The fibrous tissue that replaces normal tissue during the process of WOUND HEALING.		01.9610
Myocardial Infarction
NECROSIS of the MYOCARDIUM caused by an obstruction of the blood supply to the heart (CORONARY CIRCULATION).		01.9610