disulfiram has been researched along with Cicatrization in 2 studies
Cicatrization: The formation of fibrous tissue in the place of normal tissue during the process of WOUND HEALING. It includes scar tissue formation occurring in healing internal organs as well as in the skin after surface injuries.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Mechanisms underlying scarring are largely unknown in MMP and effective treatment options are limited." | 1.62 | Increased Fibrosis in a Mouse Model of Anti-Laminin 332 Mucous Membrane Pemphigoid Remains Unaltered by Inhibition of Aldehyde Dehydrogenase. ( Boch, K; Brinckmann, J; Busch, H; Chakievska, L; Diel, L; Fähnrich, A; Künzel, S; Patzelt, S; Pigors, M; Schmidt, E; Steenbock, H, 2021) |
| "These data suggest that progressive scarring in OMMP results from ALDH/RA fibroblast autoregulation, that the ALDH1 subfamily has a central role in immune-mediated ocular mucosal scarring, and that ALDH inhibition with disulfiram is a potential and readily translatable antifibrotic therapy." | 1.43 | Aldehyde dehydrogenase inhibition blocks mucosal fibrosis in human and mouse ocular scarring. ( Abraham, DJ; Ahadome, SD; Calder, VL; Daniels, JT; Dart, JK; Norman, JT; Ponticos, M; Rayapureddi, S; Saban, DR; Saw, VP, 2016) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 1 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Patzelt, S | 1 |
| Pigors, M | 1 |
| Steenbock, H | 1 |
| Diel, L | 1 |
| Boch, K | 1 |
| Chakievska, L | 1 |
| Künzel, S | 1 |
| Busch, H | 1 |
| Fähnrich, A | 1 |
| Brinckmann, J | 1 |
| Schmidt, E | 1 |
| Ahadome, SD | 1 |
| Abraham, DJ | 1 |
| Rayapureddi, S | 1 |
| Saw, VP | 1 |
| Saban, DR | 1 |
| Calder, VL | 1 |
| Norman, JT | 1 |
| Ponticos, M | 1 |
| Daniels, JT | 1 |
| Dart, JK | 1 |
2 other studies available for disulfiram and Cicatrization
| Article | Year |
|---|---|
Increased Fibrosis in a Mouse Model of Anti-Laminin 332 Mucous Membrane Pemphigoid Remains Unaltered by Inhibition of Aldehyde Dehydrogenase.
Topics: Aldehyde Dehydrogenase; Animals; Autoimmune Diseases; Cicatrix; Collagen; Disease Models, Animal; Di | 2021 |
Aldehyde dehydrogenase inhibition blocks mucosal fibrosis in human and mouse ocular scarring.
Topics: Adult; Aged; Aged, 80 and over; Aldehyde Dehydrogenase; Animals; Cells, Cultured; Cicatrix; Conjunct | 2016 |