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indomethacin and Cicatrization

indomethacin has been researched along with Cicatrization in 4 studies

Indomethacin: A non-steroidal anti-inflammatory agent (NSAID) that inhibits CYCLOOXYGENASE, which is necessary for the formation of PROSTAGLANDINS and other AUTACOIDS. It also inhibits the motility of POLYMORPHONUCLEAR LEUKOCYTES.
indometacin : A member of the class of indole-3-acetic acids that is indole-3-acetic acid in which the indole ring is substituted at positions 1, 2 and 5 by p-chlorobenzoyl, methyl, and methoxy groups, respectively. A non-steroidal anti-inflammatory drug, it is used in the treatment of musculoskeletal and joint disorders including osteoarthritis, rheumatoid arthritis, gout, bursitis and tendinitis.

Cicatrization: The formation of fibrous tissue in the place of normal tissue during the process of WOUND HEALING. It includes scar tissue formation occurring in healing internal organs as well as in the skin after surface injuries.

Research Excerpts

ExcerptRelevanceReference
"This study has examined the effects of prostaglandins E2 and F2a (PGE2 and PGF2a) and indomethacin on cellular inflammation in fetal rabbits."3.68Effects of prostaglandins and indomethacin on the cellular inflammatory response following surgical trauma in fetal rabbits. ( Argenta, LC; Morykwas, MJ; Perry, SL, 1993)
" The administration of antiinflammatory drugs resulted at some laser intensities in increased scores of maximum wound area, healing time, cumulated wound area, fibrosis, hydroxyproline, and hydroxylysine, being mostly pronounced for indomethacin at 0."3.68Laser induced wounds and scarring modified by antiinflammatory drugs: a murine model. ( Haedersdal, M; Poulsen, T; Wulf, HC, 1993)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's4 (100.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Morykwas, MJ1
Perry, SL1
Argenta, LC1
Haedersdal, M1
Poulsen, T1
Wulf, HC1
Frucht-Pery, J1
Levinger, S1
Zauberman, H1
Rockwell, WB1
Ehrlich, HP1

Trials

1 trial available for indomethacin and Cicatrization

ArticleYear
The effect of topical administration of indomethacin on symptoms in corneal scars and edema.
    American journal of ophthalmology, 1991, Aug-15, Volume: 112, Issue:2

    Topics: Administration, Topical; Adolescent; Adult; Aged; Aged, 80 and over; Cicatrix; Corneal Diseases; Cor

1991

Other Studies

3 other studies available for indomethacin and Cicatrization

ArticleYear
Effects of prostaglandins and indomethacin on the cellular inflammatory response following surgical trauma in fetal rabbits.
    International journal of tissue reactions, 1993, Volume: 15, Issue:4

    Topics: Animals; Cicatrix; Delayed-Action Preparations; Dinoprost; Dinoprostone; Drug Implants; Female; Fetu

1993
Laser induced wounds and scarring modified by antiinflammatory drugs: a murine model.
    Lasers in surgery and medicine, 1993, Volume: 13, Issue:1

    Topics: Administration, Oral; Animals; Burns; Cicatrix; Dose-Response Relationship, Radiation; Female; Fibro

1993
An ibuprofen-antagonized plasmin inhibitor released by human endothelial cells.
    Experimental and molecular pathology, 1991, Volume: 54, Issue:1

    Topics: Antifibrinolytic Agents; Burns; Cells, Cultured; Cicatrix; Endothelium; Fibrinolysis; Hot Temperatur

1991