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2,2'-dipyridyl and Cicatrization

2,2'-dipyridyl has been researched along with Cicatrization in 4 studies

2,2'-Dipyridyl: A reagent used for the determination of iron.
2,2'-bipyridine : A bipyridine in which the two pyridine moieties are linked by a bond between positions C-2 and C-2'.

Cicatrization: The formation of fibrous tissue in the place of normal tissue during the process of WOUND HEALING. It includes scar tissue formation occurring in healing internal organs as well as in the skin after surface injuries.

Research Excerpts

ExcerptRelevanceReference
"We conclude that the fibrous lesion scar plays a pivotal role as a growth barrier for regenerating axons in adult spinal cord and that a delay in fibrotic scarring by local inhibition of collagen biosynthesis and basement membrane deposition is a promising and unique therapeutic strategy for treating human spinal trauma."1.33Suppression of fibrous scarring in spinal cord injury of rat promotes long-distance regeneration of corticospinal tract axons, rescue of primary motoneurons in somatosensory cortex and significant functional recovery. ( Duis, S; Hamers, FP; Hermanns, S; Klapka, N; Masanneck, C; Müller, D; Müller, HW; Straten, G; Zuschratter, W, 2005)
"Only a combination of anti-scarring treatments including (i) injection of the more potent PH inhibitor [2,2'-bipyridine]-5,5'-dicarboxylic acid (BPY-DCA), (ii) selective inhibition of fibroblast proliferation and ECM production by 8-Br-cAMP, and (iii) continuous application of BPY-DCA, reduced the lesion-induced BM significantly."1.31A reliable method to reduce collagen scar formation in the lesioned rat spinal cord. ( Hermanns, S; Müller, HW; Reiprich, P, 2001)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (25.00)18.2507
2000's2 (50.00)29.6817
2010's1 (25.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ibarra, A1
Mendieta-Arbesú, E1
Suarez-Meade, P1
García-Vences, E1
Martiñón, S1
Rodriguez-Barrera, R1
Lomelí, J1
Flores-Romero, A1
Silva-García, R1
Buzoianu-Anguiano, V1
Borlongan, CV1
Frydman, TD1
Klapka, N1
Hermanns, S2
Straten, G1
Masanneck, C1
Duis, S1
Hamers, FP1
Müller, D1
Zuschratter, W1
Müller, HW2
Weidner, N1
Grill, RJ1
Tuszynski, MH1
Reiprich, P1

Other Studies

4 other studies available for 2,2'-dipyridyl and Cicatrization

ArticleYear
Motor Recovery after Chronic Spinal Cord Transection in Rats: A Proof-of-Concept Study Evaluating a Combined Strategy.
    CNS & neurological disorders drug targets, 2019, Volume: 18, Issue:1

    Topics: 2,2'-Dipyridyl; Animals; Cicatrix; Combined Modality Therapy; Evoked Potentials; Female; Freund's Ad

2019
Suppression of fibrous scarring in spinal cord injury of rat promotes long-distance regeneration of corticospinal tract axons, rescue of primary motoneurons in somatosensory cortex and significant functional recovery.
    The European journal of neuroscience, 2005, Volume: 22, Issue:12

    Topics: 2,2'-Dipyridyl; 2',3'-Cyclic-Nucleotide Phosphodiesterases; 8-Bromo Cyclic Adenosine Monophosphate;

2005
Elimination of basal lamina and the collagen "scar" after spinal cord injury fails to augment corticospinal tract regeneration.
    Experimental neurology, 1999, Volume: 160, Issue:1

    Topics: 2,2'-Dipyridyl; Animals; Axons; Basement Membrane; Cicatrix; Collagen; Extracellular Matrix; Injecti

1999
A reliable method to reduce collagen scar formation in the lesioned rat spinal cord.
    Journal of neuroscience methods, 2001, Sep-30, Volume: 110, Issue:1-2

    Topics: 2,2'-Dipyridyl; 8-Bromo Cyclic Adenosine Monophosphate; Animals; Basement Membrane; Chelating Agents

2001