hydroxyproline has been researched along with Cicatrization in 68 studies
Hydroxyproline: A hydroxylated form of the imino acid proline. A deficiency in ASCORBIC ACID can result in impaired hydroxyproline formation.
hydroxyproline : A proline derivative that is proline substituted by at least one hydroxy group.
Cicatrization: The formation of fibrous tissue in the place of normal tissue during the process of WOUND HEALING. It includes scar tissue formation occurring in healing internal organs as well as in the skin after surface injuries.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Salvianolic acid B (Sal B) is a major bioactive component of a traditional Chinese medical agent, Salvia miltiorrhiza, which has shown anti-inflammatory, anti-fibrotic and anti-proliferative properties." | 5.40 | Study on salvianolic acid B in the reduction of epidural fibrosis in laminectomy rats. ( Chen, F; Gong, H; Ji, A; Tao, H; Wang, K; Ye, F; Zhang, C; Zuo, Z, 2014) |
| " Macroscopic assessment, analysis of hydroxyproline content, and histological analysis were used to determine the therapeutic effect of the local application of RAPA on the inhibition of fibroblast proliferation and the reduction of epidural fibrosis after laminectomy." | 3.83 | Local application of rapamycin reduces epidural fibrosis after laminectomy via inhibiting fibroblast proliferation and prompting apoptosis. ( Chen, H; Dai, J; He, J; Li, X; Sun, Y; Wang, D; Wang, J; Yan, L; Zhao, S, 2016) |
| "To investigate the effect of verapamil on the prevention of epidural fibrosis in laminectomy rats." | 3.80 | Calcium channel blockers in reduction of epidural fibrosis and dural adhesions in laminectomy rats. ( Liu, W; Wang, Y; Wang, Z; Xie, P; Zhang, S, 2014) |
| " The administration of antiinflammatory drugs resulted at some laser intensities in increased scores of maximum wound area, healing time, cumulated wound area, fibrosis, hydroxyproline, and hydroxylysine, being mostly pronounced for indomethacin at 0." | 3.68 | Laser induced wounds and scarring modified by antiinflammatory drugs: a murine model. ( Haedersdal, M; Poulsen, T; Wulf, HC, 1993) |
| " Ultraviolet irradiation resulted at some of the used laser intensities in decreased scores of maximum wound area, wound healing time, cumulated wound area, and a decreased skin content of hydroxyproline, whereas the degree of the chronic fibrosis tended to increase." | 3.68 | Side effects of laser therapy, modified by ultraviolet irradiation and para-aminobenzoic acid in mice. ( Haedersdal, M; Poulsen, T; Wulf, HC, 1993) |
| "A comparison of the rates of synthesis of collagen in normal skin, normal and hypertrophic scars, and keloids has been made by measuring the rate of incorporation of [14-C]-proline into peptide-bound [14-C]-hydroxyproline by tissue minces in vitro." | 3.65 | Collagen biosynthesis in normal human skin, normal and hypertrophic scar and keloid. ( Craig, RD, 1975) |
| "The high incidence of hypertrophic scar formation is one of the many challenges to treating deep partial-thickness burns." | 1.51 | Pirfenidone Ointment Modulates the Burn Wound Bed in C57BL/6 Mice by Suppressing Inflammatory Responses. ( Dorati, R; Fourcaudot, AB; Leung, KP; Medina, JL; Sebastian, EA, 2019) |
| "The effect of HCPT on intraarticular scar adhesion was detected by macroscopic evaluation, hydroxyproline content, histological evaluation, fibroblast counting and immunohistochemical analysis." | 1.43 | Hydroxycamptothecin induces apoptosis of fibroblasts and prevents intraarticular scar adhesion in rabbits by activating the IRE-1 signal pathway. ( Chen, H; Li, X; Liang, Y; Sun, Y; Wang, J; Wang, Q; Yan, L; Zhu, G, 2016) |
| "Salvianolic acid B (Sal B) is a major bioactive component of a traditional Chinese medical agent, Salvia miltiorrhiza, which has shown anti-inflammatory, anti-fibrotic and anti-proliferative properties." | 1.40 | Study on salvianolic acid B in the reduction of epidural fibrosis in laminectomy rats. ( Chen, F; Gong, H; Ji, A; Tao, H; Wang, K; Ye, F; Zhang, C; Zuo, Z, 2014) |
| "Low neutrophil count and smaller scar width in the skin incision were found in the WP group on day 7." | 1.36 | Whey peptides improve wound healing following caesarean section in rats. ( Li, T; Li, Y; Liang, R; Wang, J; Zhang, J; Zhang, Z; Zhao, H; Zhao, M, 2010) |
| "Cells isolated from the heart scar were identified as myofibroblasts." | 1.35 | Regulatory influence of melatonin on collagen accumulation in the infarcted heart scar. ( Dabrowski, R; Drobnik, J; Jakubowski, L; Karbownik-Lewińska, M; Olczak, S; Szczepanowska, A; Słotwińska, D, 2008) |
| "Hydroxyproline was measured at the same time." | 1.33 | [Effect of basic fibroblast growth factor on wound healing of bilioenteric anastomosis]. ( Geng, Z; Wang, J; Xu, Y, 2005) |
| "Wound contraction and scar formation after cleft palate surgery impair maxillary growth and dentoalveolar development." | 1.31 | Local injection of IFN-gamma reduces the number of myofibroblasts and the collagen content in palatal wounds. ( Cornelissen, AM; Kuijpers-Jagtman, AM; Maltha, JC; Von den Hoff, JW, 2000) |
| "Scarring is markedly reduced in MRL mice compared with C57BL/6 mice, consistent with both the reduced hydroxyproline levels seen after injury and an elevated cardiomyocyte mitotic index of 10-20% for the MRL compared with 1-3% for the C57BL/6." | 1.31 | Heart regeneration in adult MRL mice. ( Bedelbaeva, K; Heber-Katz, E; Lankford, EB; Leferovich, JM; Samulewicz, S; Zhang, XM; Zwas, D, 2001) |
| "Histologic study of the scars showed they were thicker and had less cellularity in the treated animals than in the control animals." | 1.31 | Growth hormone treatment after cesarean delivery in rats increases the strength of the uterine scar. ( Bowers, D; Cohen, WR; Dutta, D; McKenzie, D; Wheeless, CR, 2001) |
| "Laser-induced wounds, scars, and hyperpigmentation were evaluated by macroscopic, histologic, and biochemical examinations." | 1.30 | Ultraviolet exposure influences laser-induced wounds, scars, and hyperpigmentation: a murine study. ( Bech-Thomsen, N; Haedersdal, M; Poulsen, T; Wulf, HC, 1998) |
| "Linear regression analysis of data on scar tissue alone showed a moderately strong positive correlation between hydroxyproline concentration and material strength (r2 = 0." | 1.29 | Rabbit medial collateral ligament scar weakness is associated with decreased collagen pyridinoline crosslink density. ( Eyre, D; Frank, C; McDonald, D; Shrive, N; Wilson, J, 1995) |
| "Polypropylene sutured scars had a higher breaking strength than silk (690 compared to 608 g, p < 0." | 1.29 | Wound breaking strength and healing after suturing noninjured tissues. ( Julià, MV; Miro, D; Sitges-Serra, A, 1995) |
| "Seven days later, the resulting scars were examined using histological, mechanical, and biochemical studies." | 1.29 | Wound healing in the fetal period: the resistance of the scar to rupture. ( Albert, A; Garcia, X; Julia, MV; Miro, D; Morales, L; Sancho, MA, 1993) |
| "For verification and quantification of scar formation (postoperative fibrosis) light microscopic examinations and determination of hydroxyproline were done, using Bergman's spectrophotometric method." | 1.29 | Effect of CO2 laser on spinal epidural fibrosis. ( Açikgöz, B; Aydin, NE; Bavbek, M; Colak, A; Renda, N, 1996) |
| "The ratios of the scar thickness to normal wall thickness were superoxide dismutase 0." | 1.27 | Superoxide dismutase does not cause scar thinning after myocardial infarction. ( Abrams, GD; Buda, AJ; Lucchesi, BR; Phan, S; Pitt, B; Shea, MJ; Vaporciyan, A; Werns, SW, 1987) |
| "The nonreperfused scars had a higher proportion of fibrous tissue (73 +/- 3%) by histological evaluation and a 35% higher hydroxyproline content (31 +/- 2 mg/g dry weight, P less than 0." | 1.27 | Effects of reperfusion after coronary artery occlusion on post-infarction scar tissue. ( Apstein, CS; Bing, OH; Connelly, CM; Dunn-Lanchantin, DM; Franzblau, C; Kloner, RA; Osmers, EL; Vogel, WM; Wiegner, AW, 1985) |
| "Pharmacological suppression of the scar reaction was tested as a possible method for improving axonal regeneration after transection and suture of the sciatic nerve of rats." | 1.27 | Nerve regeneration and pharmacological suppression of the scar reaction at the suture site. An experimental study on the effect of estrogen-progesterone, methylprednisolone-acetate and cis-hydroxyproline in rat sciatic nerve. ( Lundborg, G; Myrhage, R; Nachemson, AK; Rank, F, 1985) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 31 (45.59) | 18.7374 |
| 1990's | 15 (22.06) | 18.2507 |
| 2000's | 6 (8.82) | 29.6817 |
| 2010's | 15 (22.06) | 24.3611 |
| 2020's | 1 (1.47) | 2.80 |
| Authors | Studies |
|---|---|
| Jimi, S | 1 |
| Koizumi, S | 1 |
| Sato, K | 1 |
| Miyazaki, M | 1 |
| Saparov, A | 1 |
| Pang, Y | 1 |
| Zhang, Y | 2 |
| Huang, L | 1 |
| Xu, L | 1 |
| Wang, K | 2 |
| Wang, D | 3 |
| Guan, L | 1 |
| Yu, F | 1 |
| Chen, Z | 1 |
| Xie, X | 1 |
| Medina, JL | 1 |
| Sebastian, EA | 1 |
| Fourcaudot, AB | 1 |
| Dorati, R | 1 |
| Leung, KP | 1 |
| Wang, Z | 1 |
| Wang, Y | 1 |
| Xie, P | 1 |
| Liu, W | 2 |
| Zhang, S | 1 |
| Lv, P | 2 |
| Zhao, J | 2 |
| Su, W | 2 |
| Liang, X | 1 |
| Zhang, K | 2 |
| Lu, R | 1 |
| Chen, F | 1 |
| Zuo, Z | 1 |
| Zhang, C | 1 |
| Gong, H | 1 |
| Ye, F | 1 |
| Ji, A | 1 |
| Tao, H | 1 |
| Li, X | 2 |
| Sun, Y | 4 |
| Chen, H | 2 |
| Zhu, G | 1 |
| Liang, Y | 1 |
| Wang, Q | 3 |
| Wang, J | 6 |
| Yan, L | 4 |
| Zhao, S | 1 |
| Dai, J | 1 |
| He, J | 1 |
| Dai, S | 2 |
| Feng, X | 2 |
| Jiang, B | 2 |
| Yu, T | 2 |
| Shi, X | 1 |
| Yang, J | 1 |
| Jiang, Y | 1 |
| Lu, S | 1 |
| Zeng, Y | 1 |
| Zhao, M | 1 |
| Liang, R | 1 |
| Zhang, Z | 1 |
| Zhao, H | 1 |
| Zhang, J | 1 |
| Li, T | 1 |
| Li, Y | 1 |
| Duman, L | 1 |
| Büyükyavuz, BI | 1 |
| Altuntas, I | 1 |
| Gökcimen, A | 1 |
| Ceyhan, L | 1 |
| Darici, H | 1 |
| Aylak, F | 1 |
| Tomruk, O | 1 |
| Gu, J | 1 |
| Hu, H | 1 |
| Yin, B | 1 |
| Lv, G | 1 |
| Shu, B | 1 |
| Ni, GX | 1 |
| Zhang, LY | 1 |
| Li, XP | 1 |
| Jiang, WL | 1 |
| Zhang, LQ | 1 |
| SANDBERG, N | 1 |
| Xu, Y | 1 |
| Geng, Z | 1 |
| Drobnik, J | 1 |
| Karbownik-Lewińska, M | 1 |
| Szczepanowska, A | 1 |
| Słotwińska, D | 1 |
| Olczak, S | 1 |
| Jakubowski, L | 1 |
| Dabrowski, R | 1 |
| Hammerman, H | 1 |
| Kloner, RA | 2 |
| Hale, S | 1 |
| Schoen, FJ | 1 |
| Braunwald, E | 1 |
| Cintron, C | 1 |
| Hong, BS | 1 |
| Kublin, CL | 1 |
| Frank, C | 1 |
| McDonald, D | 1 |
| Wilson, J | 1 |
| Eyre, D | 1 |
| Shrive, N | 1 |
| Miro, D | 2 |
| Julià, MV | 2 |
| Sitges-Serra, A | 1 |
| Albert, A | 1 |
| Morales, L | 1 |
| Sancho, MA | 1 |
| Garcia, X | 1 |
| Haedersdal, M | 3 |
| Poulsen, T | 3 |
| Wulf, HC | 3 |
| Tredget, EE | 2 |
| Forsyth, N | 1 |
| Uji-Friedland, A | 1 |
| Chambers, M | 1 |
| Ghahary, A | 2 |
| Scott, PG | 2 |
| Hogg, AM | 1 |
| Burke, JF | 1 |
| Colak, A | 1 |
| Bavbek, M | 1 |
| Aydin, NE | 1 |
| Renda, N | 1 |
| Açikgöz, B | 1 |
| Chung, HT | 1 |
| Choi, BM | 1 |
| Jun, CD | 1 |
| Park, SD | 1 |
| Rim, JS | 1 |
| Bech-Thomsen, N | 1 |
| Shah, M | 1 |
| Revis, D | 1 |
| Herrick, S | 1 |
| Baillie, R | 1 |
| Thorgeirson, S | 1 |
| Ferguson, M | 1 |
| Roberts, A | 1 |
| Cornelissen, AM | 2 |
| Maltha, JC | 2 |
| Von den Hoff, HW | 1 |
| Kuijpers-Jagtman, AM | 2 |
| Takeuchi, M | 1 |
| Kilani, RT | 1 |
| Von den Hoff, JW | 1 |
| Leferovich, JM | 1 |
| Bedelbaeva, K | 1 |
| Samulewicz, S | 1 |
| Zhang, XM | 1 |
| Zwas, D | 1 |
| Lankford, EB | 1 |
| Heber-Katz, E | 1 |
| Bowers, D | 1 |
| McKenzie, D | 1 |
| Dutta, D | 1 |
| Wheeless, CR | 1 |
| Cohen, WR | 1 |
| Lamparter, S | 1 |
| Slight, SH | 1 |
| Weber, KT | 1 |
| Peacock, EE | 3 |
| Jackson, DS | 3 |
| Hallmans, G | 1 |
| Hänström, L | 1 |
| Lundgren, E | 1 |
| Hayakawa, T | 1 |
| Hashimoto, Y | 1 |
| Myokei, Y | 1 |
| Aoyama, H | 1 |
| Izawa, Y | 1 |
| Craig, RD | 3 |
| Lane, JM | 3 |
| Bora, FW | 3 |
| Black, J | 2 |
| Schofield, JD | 1 |
| Guan, ZY | 1 |
| Adzick, NS | 1 |
| Longaker, MT | 1 |
| Iannotti, JP | 1 |
| Baradet, TC | 1 |
| Tobin, M | 1 |
| Alavi, A | 1 |
| Staum, M | 1 |
| Werns, SW | 1 |
| Shea, MJ | 1 |
| Vaporciyan, A | 1 |
| Phan, S | 1 |
| Abrams, GD | 1 |
| Buda, AJ | 1 |
| Pitt, B | 1 |
| Lucchesi, BR | 1 |
| Laitung, JK | 1 |
| McClure, J | 1 |
| Shuttleworth, CA | 1 |
| Leshchinskii, LA | 1 |
| Vtorov, AE | 1 |
| Jugdutt, BI | 1 |
| Amy, RW | 1 |
| Shimizu, K | 1 |
| Takabe, S | 1 |
| Hokano, M | 1 |
| Connelly, CM | 1 |
| Vogel, WM | 1 |
| Wiegner, AW | 1 |
| Osmers, EL | 1 |
| Bing, OH | 1 |
| Dunn-Lanchantin, DM | 1 |
| Franzblau, C | 1 |
| Apstein, CS | 1 |
| Nachemson, AK | 1 |
| Lundborg, G | 1 |
| Myrhage, R | 1 |
| Rank, F | 1 |
| Tobin, G | 1 |
| Aronson, A | 1 |
| Chvapil, M | 1 |
| Judd, JT | 1 |
| Wexler, BC | 1 |
| Zamick, P | 1 |
| Mehregan, AH | 1 |
| Milsom, JP | 1 |
| Prockop, DJ | 2 |
| Longacre, JJ | 1 |
| Berry, HK | 1 |
| Johnson, HA | 1 |
| Wiethe, D | 1 |
| Chunekamrai, M | 1 |
| Ramnath, R | 1 |
| Forrest, L | 1 |
| Bazin, S | 1 |
| Nicoletis, C | 1 |
| Delbet, JP | 1 |
| Delaunay, A | 1 |
| Heppenstall, RB | 1 |
| Madden, JW | 1 |
| Shetlar, MR | 1 |
| Dobrkovsky, M | 1 |
| Linares, H | 1 |
| Villarante, R | 1 |
| Shetlar, CL | 1 |
| Larson, DL | 1 |
| Depaulis, J | 1 |
| Kowalewski, K | 1 |
| Yong, S | 1 |
1 review available for hydroxyproline and Cicatrization
| Article | Year |
|---|---|
Possible modification of scar tissue by biochemical methods.
Topics: Aminopropionitrile; Animals; Cicatrix; Collagen; Cortisone; Humans; Hydroxylysine; Hydroxyproline; L | 1979 |
67 other studies available for hydroxyproline and Cicatrization
| Article | Year |
|---|---|
Collagen-derived dipeptide Pro-Hyp administration accelerates muscle regenerative healing accompanied by less scarring after wounding on the abdominal wall in mice.
Topics: Abdominal Wall; Administration, Oral; Animals; Cell Differentiation; Cicatrix; Collagen; Dipeptides; | 2021 |
Effects and Mechanisms of Total Flavonoids from Blumea balsamifera (L.) DC. on Skin Wound in Rats.
Topics: Animals; Anti-Inflammatory Agents; Antigens, CD; Antigens, Differentiation, Myelomonocytic; Asterace | 2017 |
Pirfenidone Ointment Modulates the Burn Wound Bed in C57BL/6 Mice by Suppressing Inflammatory Responses.
Topics: Actins; Animals; Burns; Cicatrix; Cytokines; Hydroxyproline; Inflammation; Mice; Mice, Inbred C57BL; | 2019 |
Calcium channel blockers in reduction of epidural fibrosis and dural adhesions in laminectomy rats.
Topics: Animals; Calcium Channel Blockers; Cicatrix; Dura Mater; Epidural Space; Fibrosis; Hydroxyproline; I | 2014 |
An experimental novel study: hyperbaric oxygen treatment on reduction of epidural fibrosis via down-regulation of collagen deposition, IL-6, and TGF-β1.
Topics: Animals; Cicatrix; Collagen; Down-Regulation; Epidural Space; Fibroblasts; Fibrosis; Gene Expression | 2015 |
Immunomodulatory effectiveness of licofelone in preventing epidural fibrosis in post-laminectomy rat.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cicatrix; Disease Models, Animal; Double-Blind Met | 2015 |
Experimental research on the effect of mitomycin C fibrin gel on spinal peridural scar tissue in rats.
Topics: Adhesiveness; Animals; Cicatrix; Fibrin; Gels; Hydroxyproline; Male; Mitomycin; Rats; Rats, Sprague- | 2014 |
Study on salvianolic acid B in the reduction of epidural fibrosis in laminectomy rats.
Topics: Animals; Anti-Inflammatory Agents; Benzofurans; Cell Proliferation; Cicatrix; Double-Blind Method; D | 2014 |
Hydroxycamptothecin induces apoptosis of fibroblasts and prevents intraarticular scar adhesion in rabbits by activating the IRE-1 signal pathway.
Topics: Adhesiveness; Animals; Apoptosis; Camptothecin; Cell Survival; Cicatrix; Collagen; Dose-Response Rel | 2016 |
Local application of rapamycin reduces epidural fibrosis after laminectomy via inhibiting fibroblast proliferation and prompting apoptosis.
Topics: Animals; Apoptosis; Cell Proliferation; Cells, Cultured; Cicatrix; Epidural Space; Fibroblasts; Fibr | 2016 |
The effect of mitomycin C in reducing intraarticular adhesion after knee surgery in rabbits.
Topics: Administration, Topical; Animals; Cell Count; Cicatrix; Collagen; Disease Models, Animal; Femur; Fib | 2010 |
Dermal fibroblast behaviour on micropatterned substrates with different pattern geometries.
Topics: Actins; Adult; Aged; Cell Adhesion; Cell Culture Techniques; Cell Survival; Cicatrix; Collagen; Fema | 2011 |
Whey peptides improve wound healing following caesarean section in rats.
Topics: Albumins; Animals; Cesarean Section; Cicatrix; Dermatologic Agents; Female; Hydroxyproline; Milk Pro | 2010 |
The efficacy of single-dose 5-fluorouracil therapy in experimental caustic esophageal burn.
Topics: Animals; Burns, Chemical; Caustics; Cell Differentiation; Cell Division; Cicatrix; Drug Evaluation, | 2011 |
A comparative study of the preventive effects of mitomycin C and chitosan on intraarticular adhesion after knee surgery in rabbits.
Topics: Alkylating Agents; Animals; Chitosan; Cicatrix; Disease Models, Animal; Fibroblasts; Hydroxyproline; | 2012 |
High-power helium-neon laser irradiation inhibits the growth of traumatic scars in vitro and in vivo.
Topics: Adolescent; Adult; Animals; Cell Proliferation; Cells, Cultured; Cicatrix; Cicatrix, Hypertrophic; C | 2013 |
ON THE HEALING OF WOUNDS IN RATS DURING THE PERIOD OF CICATRIZATION.
Topics: Cicatrix; Collagen; Granulation Tissue; Hydroxyproline; Rats; Research; Skin; Wound Healing | 1963 |
[Effect of basic fibroblast growth factor on wound healing of bilioenteric anastomosis].
Topics: Animals; Choledochostomy; Cicatrix; Dogs; Female; Fibroblast Growth Factor 2; Hydroxyproline; Male; | 2005 |
Regulatory influence of melatonin on collagen accumulation in the infarcted heart scar.
Topics: Animals; Cells, Cultured; Cicatrix; Collagen; Fibroblasts; Gene Expression Regulation; Hydroxyprolin | 2008 |
Dose-dependent effects of short-term methylprednisolone on myocardial infarct extent, scar formation, and ventricular function.
Topics: Animals; Cicatrix; Dogs; Dose-Response Relationship, Drug; Echocardiography; Female; Heart Ventricle | 1983 |
Quantitative analysis of collagen from normal developing corneas and corneal scars.
Topics: Age Factors; Animals; Cicatrix; Collagen; Cornea; Electrophoresis, Polyacrylamide Gel; Fetus; Hydrox | 1981 |
Rabbit medial collateral ligament scar weakness is associated with decreased collagen pyridinoline crosslink density.
Topics: Amino Acids; Animals; Cicatrix; Collagen; Female; Hydroxyproline; Linear Models; Medial Collateral L | 1995 |
Wound breaking strength and healing after suturing noninjured tissues.
Topics: Animals; Cicatrix; Female; Hydroxyproline; Insect Proteins; Mice; Mice, Inbred Strains; Polyglactin | 1995 |
Wound healing in the fetal period: the resistance of the scar to rupture.
Topics: Age Factors; Animals; Animals, Newborn; Body Weight; Cicatrix; Collagen; Electrocoagulation; Estheti | 1993 |
Laser induced wounds and scarring modified by antiinflammatory drugs: a murine model.
Topics: Administration, Oral; Animals; Burns; Cicatrix; Dose-Response Relationship, Radiation; Female; Fibro | 1993 |
Gas chromatography-mass spectrometry determination of 18O2 in 18O-labelled 4-hydroxyproline for measurement of collagen synthesis and intracellular degradation.
Topics: Cicatrix; Collagen; Fibroblasts; Gas Chromatography-Mass Spectrometry; Humans; Hydroxyproline; Isoto | 1993 |
Side effects of laser therapy, modified by ultraviolet irradiation and para-aminobenzoic acid in mice.
Topics: 4-Aminobenzoic Acid; Animals; Cicatrix; Female; Fibrosis; Hydroxylysine; Hydroxyproline; Laser Thera | 1993 |
Effect of CO2 laser on spinal epidural fibrosis.
Topics: Animals; Cicatrix; Epidural Space; Fibrosis; Guinea Pigs; Hydroxyproline; Laminectomy; Laser Therapy | 1996 |
Antisense transforming growth factor-beta 1 in wound healing.
Topics: Animals; Blotting, Northern; Cicatrix; Drug Evaluation, Preclinical; Enzyme Induction; Fibrosis; Gen | 1997 |
Ultraviolet exposure influences laser-induced wounds, scars, and hyperpigmentation: a murine study.
Topics: Animals; Cicatrix; Contracture; Copper; Dermatologic Surgical Procedures; Esthetics; Facial Dermatos | 1998 |
Role of elevated plasma transforming growth factor-beta1 levels in wound healing.
Topics: Animals; Cicatrix; Hydroxyproline; Immunohistochemistry; Male; Mice; Mice, Inbred C57BL; Mice, Inbre | 1999 |
Palatal mucoperiosteal wound healing in the rat.
Topics: Animals; Case-Control Studies; Cicatrix; Collagen; DNA; Extracellular Matrix; Follow-Up Studies; Gly | 1999 |
The antifibrogenic effects of liposome-encapsulated IFN-alpha2b cream on skin wounds.
Topics: Animals; Cicatrix; Dosage Forms; Extracellular Matrix; Female; Fibrosis; Guinea Pigs; Hydroxyproline | 1999 |
Local injection of IFN-gamma reduces the number of myofibroblasts and the collagen content in palatal wounds.
Topics: Actin Cytoskeleton; Analysis of Variance; Animals; Chi-Square Distribution; Cicatrix; Collagen; Cont | 2000 |
Heart regeneration in adult MRL mice.
Topics: Animals; Biomarkers; Cicatrix; Cold Temperature; Collagen; Collagen Type I; Collagen Type I, alpha 1 | 2001 |
Growth hormone treatment after cesarean delivery in rats increases the strength of the uterine scar.
Topics: Animals; Cesarean Section; Cicatrix; Female; Growth Hormone; Hydroxyproline; Postoperative Care; Pre | 2001 |
Doxycycline and tissue repair in rats.
Topics: Animals; Anti-Bacterial Agents; Bacterial Infections; Cicatrix; Collagen; Collagen Type I; Coloring | 2002 |
Some biologic and technical considerations in the repair of long tendons.
Topics: Aminopropionitrile; Animals; Cadaver; Cicatrix; Collagen; Connective Tissue; Dogs; Fingers; Foreign- | 1977 |
The effect of zinc tape upon wound healing. A biochemical, histochemical and histological study in rats.
Topics: Acid Phosphatase; Administration, Topical; Alkaline Phosphatase; Animals; Cicatrix; Histocytochemist | 1979 |
Changes in type of collagen during the development of human post-burn hypertrophic scars.
Topics: Adult; Amino Acids; Burns; Child; Child, Preschool; Cicatrix; Collagen; Female; Humans; Hydroxyproli | 1979 |
Collagen biosynthesis in normal human skin, normal and hypertrophic scar and keloid.
Topics: Carbon Radioisotopes; Cicatrix; Collagen; Humans; Hydroxyproline; Hypertrophy; In Vitro Techniques; | 1975 |
cis-hydroxyproline limits work necessary to flex a digit after tendon injury.
Topics: Animals; Biomechanical Phenomena; Cicatrix; Collagen; Disease Models, Animal; Dose-Response Relation | 1975 |
Collagen biosynthesis in normal and hypertrophic scars and keloid as a function of the duration of the scar.
Topics: Cicatrix; Collagen; Humans; Hydroxyproline; Hypertrophy; In Vitro Techniques; Keloid; Kinetics; Prol | 1975 |
[Significance of determination of serum and urinary hydroxyproline in healthy subjects and patients with hyperplastic scars].
Topics: Adolescent; Adult; Cicatrix; Collagen; Female; Humans; Hydroxyproline; Male | 1991 |
Scarless wound healing in the fetus: the role of the extracellular matrix.
Topics: Age Factors; Amniotic Fluid; Animals; Cicatrix; Collagen; Extracellular Matrix; Fetus; Humans; Hyalu | 1991 |
Synthesis and characterization of magnetically responsive albumin microspheres containing cis-hydroxyproline for scar inhibition.
Topics: Animals; Chickens; Cicatrix; Collagen; Female; Fibroblasts; Hydroxyproline; Infusions, Intra-Arteria | 1991 |
Superoxide dismutase does not cause scar thinning after myocardial infarction.
Topics: Animals; Cicatrix; Dogs; Echocardiography; Granulation Tissue; Hydroxyproline; Male; Myocardial Infa | 1987 |
The fibrous capsules around static and dynamic implants: their biochemical, histological, and ultrastructural characteristics.
Topics: Cicatrix; Collagen; Fibroblasts; Humans; Hydroxyproline; Microscopy, Electron; Prostheses and Implan | 1987 |
The dynamics of healing processes in the heart muscle in acute myocardial infarction.
Topics: Adult; Aged; Cicatrix; Collagen; Female; Humans; Hydroxyproline; Male; Middle Aged; Myocardial Infar | 1987 |
Healing after myocardial infarction in the dog: changes in infarct hydroxyproline and topography.
Topics: Animals; Arterial Occlusive Diseases; Cicatrix; Dilatation, Pathologic; Dogs; Hydroxyproline; Myocar | 1986 |
Correlation between number of placental detachments and amount of postpartum uterine involution in mice.
Topics: Animals; Cicatrix; Female; Hydroxyproline; Mice; Mice, Inbred Strains; Organ Size; Placenta; Postpar | 1985 |
Effects of reperfusion after coronary artery occlusion on post-infarction scar tissue.
Topics: Animals; Arteries; Cicatrix; Collagen; Coronary Vessels; Desmosine; Elastin; Hydroxyproline; Ligatio | 1985 |
Nerve regeneration and pharmacological suppression of the scar reaction at the suture site. An experimental study on the effect of estrogen-progesterone, methylprednisolone-acetate and cis-hydroxyproline in rat sciatic nerve.
Topics: Animals; Anti-Inflammatory Agents; Cicatrix; Connective Tissue; Depression, Chemical; Drug Combinati | 1985 |
Wound healing and collagen degradation in calcium-EDTA-treated rats.
Topics: Animals; Calcium; Cicatrix; Collagen; Connective Tissue; Edetic Acid; Female; Granulation Tissue; Hu | 1974 |
Myocardial connective tissue metabolism in response to injury. Histological and chemical studies of mucopolysaccharide and collagen in rat hearts after isoproterenol-induced infaraction.
Topics: Animals; Arteriosclerosis; Cicatrix; Collagen; Connective Tissue; Female; Glycosaminoglycans; Hexosa | 1969 |
Effect of 1-tri-iodothyronine on marginal scars of skin grafted burns in rats.
Topics: Animals; Burns; Cicatrix; Collagen; Fibroblasts; Glycosaminoglycans; Histocytochemistry; Hydroxyprol | 1973 |
Collagen degradation in cultured keloid and hypertrophic scar tissue.
Topics: Adolescent; Adult; Aged; Carbon Radioisotopes; Child; Child, Preschool; Cicatrix; Collagen; Culture | 1973 |
Inhibitors of collagen biosynthesis as a means of controlling scar formation in tendon injury.
Topics: Aminopropionitrile; Animals; Chelating Agents; Cicatrix; Collagen; Hindlimb; Hydroxyproline; Penicil | 1972 |
The relation of the ultrastructure of collagen to scar formation and its surgical management.
Topics: Burns; Chromatography; Cicatrix; Collagen; Contracture; Female; Humans; Hydroxyproline; Male; Peptid | 1968 |
Intermolecular cross-linking of collagen in human and guinea pig scar tissue.
Topics: Amino Acids; Animals; Cicatrix; Collagen; Cysteamine; Female; Guinea Pigs; Hexosamines; Humans; Hydr | 1971 |
[Degree of collagen maturation in normal and keloid cicatrix].
Topics: Aging; Cicatrix; Collagen; Humans; Hydroxyproline; Keloid; Skin | 1970 |
Inhibition of scar formation by the proline analog cis-hydroxyproline.
Topics: Animals; Cicatrix; Disease Models, Animal; Hindlimb; Hydroxyproline; Male; Postoperative Complicatio | 1972 |
Studies on the biology of collagen during wound healing. 3. Dynamic metabolism of scar collagen and remodeling of dermal wounds.
Topics: Animals; Cicatrix; Collagen; Female; Hydroxyproline; Proline; Rats; Skin; Tritium; Wound Healing | 1971 |
The hypertrophic scar. Glycoprotein and collagen components of burn scars.
Topics: Adolescent; Adult; Age Factors; Aged; Burns; Child; Child, Preschool; Cicatrix; Citrates; Collagen; | 1971 |
[Study of a physiologic regulator of cicatrization (N acetyl-hydroxyproline). Apropos of 15 clincal cases].
Topics: Adult; Aged; Child; Child, Preschool; Cicatrix; Female; Humans; Hydroxyproline; Male; Middle Aged; W | 1971 |
Symposium on biological control of scar tissue.
Topics: Aminopropionitrile; Animals; Cicatrix; Collagen; Humans; Hydroxyproline; Nitriles; Penicillamine; Ri | 1968 |
Effect of growth hormone and an anabolic steroid on hydroxyproline in healing dermal wounds in rats.
Topics: Animals; Body Weight; Cicatrix; Collagen; Growth Hormone; Hydroxyproline; In Vitro Techniques; Injec | 1968 |