deferoxamine has been researched along with Cicatrization in 2 studies
Deferoxamine: Natural product isolated from Streptomyces pilosus. It forms iron complexes and is used as a chelating agent, particularly in the mesylate form.
desferrioxamine B : An acyclic desferrioxamine that is butanedioic acid in which one of the carboxy groups undergoes formal condensation with the primary amino group of N-(5-aminopentyl)-N-hydroxyacetamide and the second carboxy group undergoes formal condensation with the hydroxyamino group of N(1)-(5-aminopentyl)-N(1)-hydroxy-N(4)-[5-(hydroxyamino)pentyl]butanediamide. It is a siderophore native to Streptomyces pilosus biosynthesised by the DesABCD enzyme cluster as a high affinity Fe(III) chelator.
Cicatrization: The formation of fibrous tissue in the place of normal tissue during the process of WOUND HEALING. It includes scar tissue formation occurring in healing internal organs as well as in the skin after surface injuries.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Deferoxamine treatment presents a potential therapeutic avenue through which to target impaired wound healing in patients following radiotherapy." | 1.72 | Transdermal deferoxamine administration improves excisional wound healing in chronically irradiated murine skin. ( Abbas, DB; Churukian, A; Griffin, M; Guardino, N; Guo, JL; Gurtner, GC; Lavin, CV; Lintel, H; Longaker, MT; Momeni, A; Wan, DC, 2022) |
| "Lesion-induced scarring is a major impediment for regeneration of injured axons in the central nervous system (CNS)." | 1.42 | Pharmacological Suppression of CNS Scarring by Deferoxamine Reduces Lesion Volume and Increases Regeneration in an In Vitro Model for Astroglial-Fibrotic Scarring and in Rat Spinal Cord Injury In Vivo. ( Brazda, N; Estrada, V; Faissner, A; König, B; Krafft, S; Müller, HW; Vogelaar, CF; Ziegler, B, 2015) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 1 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lintel, H | 1 |
| Abbas, DB | 1 |
| Lavin, CV | 1 |
| Griffin, M | 1 |
| Guo, JL | 1 |
| Guardino, N | 1 |
| Churukian, A | 1 |
| Gurtner, GC | 1 |
| Momeni, A | 1 |
| Longaker, MT | 1 |
| Wan, DC | 1 |
| Vogelaar, CF | 1 |
| König, B | 1 |
| Krafft, S | 1 |
| Estrada, V | 1 |
| Brazda, N | 1 |
| Ziegler, B | 1 |
| Faissner, A | 1 |
| Müller, HW | 1 |
2 other studies available for deferoxamine and Cicatrization
| Article | Year |
|---|---|
Transdermal deferoxamine administration improves excisional wound healing in chronically irradiated murine skin.
Topics: Animals; Cicatrix; Collagen; Deferoxamine; Humans; Mice; Nitric Oxide; Radiation Injuries; Skin; Wou | 2022 |
Pharmacological Suppression of CNS Scarring by Deferoxamine Reduces Lesion Volume and Increases Regeneration in an In Vitro Model for Astroglial-Fibrotic Scarring and in Rat Spinal Cord Injury In Vivo.
Topics: Animals; Astrocytes; Axons; Central Nervous System; Cicatrix; Collagen Type IV; Cyclic AMP; Deferoxa | 2015 |