Page last updated: 2024-10-31

mirtazapine and Menopause

mirtazapine has been researched along with Menopause in 4 studies

Mirtazapine: A piperazinoazepine tetracyclic compound that enhances the release of NOREPINEPHRINE and SEROTONIN through blockage of presynaptic ALPHA-2 ADRENERGIC RECEPTORS. It also blocks both 5-HT2 and 5-HT3 serotonin receptors and is a potent HISTAMINE H1 RECEPTOR antagonist. It is used for the treatment of depression, and may also be useful for the treatment of anxiety disorders.

Menopause: The last menstrual period. Permanent cessation of menses (MENSTRUATION) is usually defined after 6 to 12 months of AMENORRHEA in a woman over 45 years of age. In the United States, menopause generally occurs in women between 48 and 55 years of age.

Research Excerpts

ExcerptRelevanceReference
"Mirtazapine is an effective treatment for major depression in perimenopausal and postmenopausal women whose depression precedes ERT use and does not respond to ERT or whose depression develops after ERT is initiated."6.70An open trial of mirtazapine in menopausal women with depression unresponsive to estrogen replacement therapy. ( Cohen, LS; Groninger, H; Joffe, H; Nonacs, R; Soares, C; Soares, CN, 2001)
"Mirtazapine is an effective treatment for major depression in perimenopausal and postmenopausal women whose depression precedes ERT use and does not respond to ERT or whose depression develops after ERT is initiated."2.70An open trial of mirtazapine in menopausal women with depression unresponsive to estrogen replacement therapy. ( Cohen, LS; Groninger, H; Joffe, H; Nonacs, R; Soares, C; Soares, CN, 2001)
"The latter yielded results on VMS, insomnia, circadian rhythm disorders, obstructive sleep apnea (OSA) and restless leg syndrome (RLS)."2.61Italian Association of Sleep Medicine (AIMS) position statement and guideline on the treatment of menopausal sleep disorders. ( Aricò, I; Bonanni, E; Bonsignore, M; Caretto, M; Caruso, D; Di Perri, MC; Galletta, S; Lecca, RM; Lombardi, C; Maestri, M; Miccoli, M; Palagini, L; Provini, F; Puligheddu, M; Savarese, M; Silvestri, R; Simoncini, T; Spaggiari, MC, 2019)
"Mirtazapine is an antidepressant with mode of action different from other currently available antidepressants."2.40Mirtazapine: other indications. ( Falkai, P, 1999)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (25.00)18.2507
2000's2 (50.00)29.6817
2010's1 (25.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Silvestri, R1
Aricò, I1
Bonanni, E1
Bonsignore, M1
Caretto, M1
Caruso, D1
Di Perri, MC1
Galletta, S1
Lecca, RM1
Lombardi, C1
Maestri, M1
Miccoli, M1
Palagini, L1
Provini, F1
Puligheddu, M1
Savarese, M1
Spaggiari, MC1
Simoncini, T1
Albertazzi, P1
Falkai, P1
Joffe, H1
Groninger, H1
Soares, CN1
Nonacs, R1
Cohen, LS1
Soares, C1

Reviews

3 reviews available for mirtazapine and Menopause

ArticleYear
Italian Association of Sleep Medicine (AIMS) position statement and guideline on the treatment of menopausal sleep disorders.
    Maturitas, 2019, Volume: 129

    Topics: Antidepressive Agents; Cognitive Behavioral Therapy; Continuous Positive Airway Pressure; Depression

2019
Noradrenergic and serotonergic modulation to treat vasomotor symptoms.
    The journal of the British Menopause Society, 2006, Volume: 12, Issue:1

    Topics: Citalopram; Cyclohexanols; Female; Fluoxetine; Hot Flashes; Humans; Menopause; Mianserin; Mirtazapin

2006
Mirtazapine: other indications.
    The Journal of clinical psychiatry, 1999, Volume: 60 Suppl 17

    Topics: Adult; Antidepressive Agents, Tricyclic; Anxiety Disorders; Clinical Trials as Topic; Depressive Dis

1999

Trials

1 trial available for mirtazapine and Menopause

ArticleYear
An open trial of mirtazapine in menopausal women with depression unresponsive to estrogen replacement therapy.
    Journal of women's health & gender-based medicine, 2001, Volume: 10, Issue:10

    Topics: Adult; Antidepressive Agents; Depression; Estradiol; Female; Hormone Replacement Therapy; Humans; Me

2001