etiocholanolone and Menopause studies

Etiocholanolone: The 5-beta-reduced isomer of ANDROSTERONE. Etiocholanolone is a major metabolite of TESTOSTERONE and ANDROSTENEDIONE in many mammalian species including humans. It is excreted in the URINE.
3alpha-hydroxy-5beta-androstan-17-one : An androstanoid that is 5beta-androstane substituted by an alpha-hydroxy group at position 3 and an oxo group at position 17. It is a metabolite of testosterone in mammals.

Menopause: The last menstrual period. Permanent cessation of menses (MENSTRUATION) is usually defined after 6 to 12 months of AMENORRHEA in a woman over 45 years of age. In the United States, menopause generally occurs in women between 48 and 55 years of age.

Research Excerpts

Excerpt	Relevance	Reference
"Etiocholanolone levels have been measured in both premastectomy and postoperative urines from 86 women with early breast cancer."	7.66	Urinary etiocholanolone and prognosis in early carcinoma of the breast. ( Hamilton, T; Miller, WR; Prescott, RJ, 1978)
"Androsterone and aetiocholanolone were measured in urine specimens obtained from 218 women with early breast cancer."	3.66	Urinary androgen metabolites and recurrence rates in early breast cancer. ( Bulbrook, RD; Hayward, JL; Millis, RR; Thomas, BS, 1982)
"Etiocholanolone levels have been measured in both premastectomy and postoperative urines from 86 women with early breast cancer."	3.66	Urinary etiocholanolone and prognosis in early carcinoma of the breast. ( Hamilton, T; Miller, WR; Prescott, RJ, 1978)
"Measurement of the excretion of total 17-ketosteroids, androsterone, etiocholanolone, and dehydroepiandrosterone demonstrate in contrast to the well known age dependency of normal women in cases of both mastopathia and breast cancer the following results: 1."	3.65	Investigation of 17-ketosteriod excretion in mastopathia and premenopausal breast cancer. ( Eckhardt, S; Hindy, I; Prajda, N; Sellei, C; Tapolcsányi, L, 1975)
"The premenopausal patients with early breast cancer excreted subnormal amounts of five steroids (11-hydroxyandrosterone, 11-hydroxyetiocholanolone, pregnanediol, pregnanetriol, and tetrahydrocorticosterone) and increased amounts of tetrahydrocortisol as compared with the normal subjects of corresponding ages."	1.25	Hormonal status of breast cancer. II. Abnormal urinary steroid excretion. ( Aoki, K; Kodama, M; Kodama, T; Totania, R; Yoshida, M, 1975)
"In patients with breast and prostate cancer hormone excretion patterns differ in a similar way from patterns in persons without cancer."	1.24	HORMONE EXCRETION PATTERNS IN BREAST AND PROSTATE CANCER ARE ABNORMAL. ( HOPKINS, CE; MARMORSTON, J; STERN, E; WEINER, JM, 1964)

Timeframe	Studies, this research(%)	All Research%
pre-1990	29 (96.67)	18.7374
1990's	1 (3.33)	18.2507
2000's	0 (0.00)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Authors	Studies
STERN, E	2
HOPKINS, CE	2
WEINER, JM	1
MARMORSTON, J	2
HOLLO, I	2
FEHER, T	1
CROWLEY, LG	1
MYERS, SM	1
Thomas, BS	1
Bulbrook, RD	2
Hayward, JL	2
Millis, RR	1
Kiricuta, I	1
Frenkel, Z	1
Hindy, I	1
Prajda, N	1
Tapolcsányi, L	1
Sellei, C	1
Eckhardt, S	1
Görlich, M	1
Heise, E	1
Wang, DY	1
Kumaoka, S	1
Takatani, O	1
Abe, O	1
Utsunomiya, J	1
Kirschner, MA	1
Prescott, RJ	2
Miller, WR	3
Hamilton, T	3
Pfaffenberger, CD	2
Horning, EC	2
Malinak, LR	1
Kodama, M	2
Kodama, T	2
Totani, R	1
Yoshida, M	1
Totania, R	1
Aoki, K	1
Champion, HR	2
Wallace, IW	1
Forrest, AP	2
Cameron, EH	1
Griffiths, K	1
Radowicki, S	1
Tyc, M	1
Małunowicz, E	1
Dowgiałło-Smolarczyk, J	1
Sarfaty, G	2
Pitt, P	1
Tallis, M	2
Kuramoto, S	1
Oertel, GW	1
Menzel, P	1
Rindt, W	1
Bogdanova, AG	1
Lemon, HM	1
Bruce, J	2
de Waard, F	2
Thijssen, JH	1
Goldzieher, JW	1
Axelrod, LR	1
Kammer, CS	1
Thyssen, JH	1
Veeman, W	1
Sander, PC	1

Article	Year
The role of hormones in the etiology of human breast cancer. Cancer, 1977, Volume: 39, Issue:6 Suppl Topics: 17-Ketosteroids; Androgens; Androsterone; Breast Neoplasms; Contraceptives, Oral, Hormonal; Estradio	1977
Endocrine influences on human mammary cancer formation. A critique. Cancer, 1969, Volume: 23, Issue:4 Topics: Adrenocorticotropic Hormone; Androgens; Androsterone; Animals; Binding Sites; Breast Diseases; Breas	1969

Article	Year
HORMONE EXCRETION PATTERNS IN BREAST AND PROSTATE CANCER ARE ABNORMAL. Science (New York, N.Y.), 1964, Aug-14, Volume: 145, Issue:3633 Topics: 17-Ketosteroids; Adrenal Cortex Hormones; Aged; Androsterone; Breast Neoplasms; Creatine; Creatinine	1964
STUDIES ON POSTMENOPAUSAL OSTEOPOROSIS. I. URINARY EXCRETION OF 17-KETOSTEROID FRACTIONS IN POSTMENOPAUSAL OSTEOPOROSIS. Acta medica Academiae Scientiarum Hungaricae, 1964, Volume: 20 Topics: 17-Ketosteroids; Androsterone; Body Fluids; Etiocholanolone; Female; Humans; Menopause; Metabolism;	1964
STUDIES ON POSTMENOPAUSAL OSTEOPOROSIS. II. EFFECT OF TESTOSTERONE AND ACTH LOADING ON THE URINARY EXCRETION OF 17-KETOSTEROID FRACTIONS IN POSTMENOPAUSAL OSTEOPOROSIS. Acta medica Academiae Scientiarum Hungaricae, 1964, Volume: 20 Topics: 17-Ketosteroids; Adrenocorticotropic Hormone; Androsterone; Body Fluids; Etiocholanolone; Female; Hu	1964
I. URINARY EXCRETION OF NEUTRAL 17-KETOSTEROIDS AND PREGNANDEIOL BY PATIENTS WITH BREAST CANCER AND BENIGN BREAST DISEASE. American journal of obstetrics and gynecology, 1965, Jun-15, Volume: 92 Topics: 17-Ketosteroids; Androsterone; Breast Diseases; Breast Neoplasms; Dehydroepiandrosterone; Etiocholan	1965
Urinary androgen metabolites and recurrence rates in early breast cancer. European journal of cancer & clinical oncology, 1982, Volume: 18, Issue:5 Topics: Androsterone; Breast Neoplasms; Etiocholanolone; Female; Humans; Mastectomy; Menopause; Neoplasm Rec	1982
Some aspects of the endocrine status in the inflammatory breast carcinoma (Mastitis carcinosa). Archiv fur Geschwulstforschung, 1982, Volume: 52, Issue:1 Topics: 17-Ketosteroids; Adult; Age Factors; Aged; Breast Neoplasms; Estrogens; Etiocholanolone; Female; Hum	1982
Investigation of 17-ketosteriod excretion in mastopathia and premenopausal breast cancer. Archiv fur Geschwulstforschung, 1975, Volume: 45, Issue:5 Topics: 17-Ketosteroids; Adult; Androsterone; Breast Neoplasms; Dehydroepiandrosterone; Etiocholanolone; Fem	1975
Urinary excretion of 17-ketosteroids in patients suffering from mammary cancer. Archiv fur Geschwulstforschung, 1975, Volume: 45, Issue:5 Topics: 17-Ketosteroids; Aged; Breast Neoplasms; Dehydroepiandrosterone; Etiocholanolone; Female; Humans; Me	1975
Plasma dehydroepiandrosterone and androsterone sulphates, androstenedione and urinary androgen metabolites in normal British and Japanese women. European journal of cancer, 1976, Volume: 12, Issue:12 Topics: Adolescent; Adult; Age Factors; Androgens; Androstenedione; Androsterone; Asian People; Dehydroepian	1976
Urinary etiocholanolone and prognosis in early carcinoma of the breast. Journal of surgical oncology, 1978, Volume: 10, Issue:4 Topics: Breast Neoplasms; Carcinoma; Etiocholanolone; Female; Humans; Mastectomy; Menopause; Neoplasm Stagin	1978
Additional data supporting sex differences in human urinary steroid metabolic profiles. Analytical biochemistry, 1978, Aug-01, Volume: 88, Issue:2 Topics: 3-Oxo-5-alpha-Steroid 4-Dehydrogenase; Adult; Androsterone; Cell Differentiation; Etiocholanolone; F	1978
High-resolution biomedical gas chromatography. Study of urinary steroid metabolite ratios of women with breast lesions using open-tubular glass capillary columns. Journal of chromatography, 1978, Oct-01, Volume: 158 Topics: Adult; Age Factors; Aged; Androsterone; Breast Diseases; Breast Neoplasms; Chromatography, Gas; Cyst	1978
Hormonal status of cervical cancer. Journal of the National Cancer Institute, 1977, Volume: 59, Issue:1 Topics: Adult; Age Factors; Aged; Androsterone; Etiocholanolone; Female; Humans; Menopause; Menstruation; Mi	1977
Hormonal status of breast cancer. II. Abnormal urinary steroid excretion. Journal of the National Cancer Institute, 1975, Volume: 54, Issue:6 Topics: 11-Hydroxycorticosteroids; 17-Hydroxycorticosteroids; 17-Ketosteroids; Adrenal Cortex Hormones; Agin	1975
Urinary aetiocholanolone in patients with early breast cancer from South East Scotland and South Wales. British journal of cancer, 1975, Volume: 32, Issue:5 Topics: Adenofibroma; Adult; Age Factors; Aged; Analysis of Variance; Breast Neoplasms; Etiocholanolone; Fem	1975
[Urinary steroid profiling in postmenopausal women (preliminary notes)]. Ginekologia polska, 1992, Volume: 63, Issue:5 Topics: Androsterone; Chromatography, Gas; Etiocholanolone; Female; Humans; Menopause; Middle Aged	1992
Basic results of a study of bilateral adrenalectomy for advanced breast cancer. Urinary steroids and related data in 148 patients. The Medical journal of Australia, 1973, Nov-10, Volume: 2, Issue:19 Topics: 17-Ketosteroids; Adrenalectomy; Adult; Androsterone; Body Surface Area; Breast; Breast Neoplasms; Ch	1973
Probability of a woman with advanced breast cancer responding to adrenalectomy or hypophysectomy. Lancet (London, England), 1970, Oct-03, Volume: 2, Issue:7675 Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adrenalectomy; Adult; Age Factors; Androsterone; Breast	1970
[Study of the dynamics of female urinary 11-deoxy-17-ketosteroid fractions studies by gas-liquid chromatography]. Nihon Sanka Fujinka Gakkai zasshi, 1968, Volume: 20, Issue:12 Topics: 17-Ketosteroids; Androsterone; Chromatography, Gas; Dehydroepiandrosterone; Etiocholanolone; Female;	1968
[Dehydroepiandrosterone, androsterone and etiocholanolone in plasma and following urine administration of dehydroepiandrosterone sulfate]. Arzneimittel-Forschung, 1970, Volume: 20, Issue:3 Topics: Adult; Androsterone; Dehydroepiandrosterone; Etiocholanolone; Female; Humans; Male; Menopause; Stimu	1970
Hormonal influences in breast cancer. Proceedings of the Royal Society of Medicine, 1971, Volume: 64, Issue:5 Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adrenalectomy; Adult; Age Factors; Androsterone; Animals	1971
[Treatment of the menopause syndrome with dehydroepiandrosterone sulfate]. Annales Universitatis Saraviensis. Medizin, 1971, Volume: 18, Issue:1 Topics: Administration, Oral; Androstenes; Androsterone; Dehydroepiandrosterone; Endometrium; Estrogens; Eti	1971
[Influence of age and menopause duration on the excretion of steroid hormones in precancerous conditions and cancer of the breast]. Voprosy onkologii, 1974, Volume: 20, Issue:7 Topics: Adult; Age Factors; Androsterone; Breast Diseases; Breast Neoplasms; Dehydroepiandrosterone; Etiocho	1974
Influence of age, stage of disease, and menstrual status on urinary steroids in women with early breast cancer. The British journal of surgery, 1971, Volume: 58, Issue:11 Topics: 17-Hydroxycorticosteroids; Age Factors; Breast Neoplasms; Etiocholanolone; Female; Menopause; Menstr	1971
Relationship between hormonal cytology and steroid excretion in post-menopausal women. The Journal of endocrinology, 1970, Volume: 48, Issue:4 Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Aged; Androsterone; Breast Neoplasms; Estriol; Estrogens	1970
In vivo conversion of 4-14C progesterone to androsterone and etiocholanolone in man. Steroids, 1971, Volume: 17, Issue:2 Topics: Adult; Androsterone; Carbon Isotopes; Etiocholanolone; Female; Glucuronates; Humans; Male; Menopause	1971
Steroid hormone excretion pattern in women with endometrial carcinoma. Cancer, 1968, Volume: 22, Issue:5 Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Aged; Body Weight; Chromatography, Gas; Diabetes Mellitu	1968

etiocholanolone and Menopause

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