Page last updated: 2024-11-06

prednisolone and Menopause

prednisolone has been researched along with Menopause in 35 studies

Prednisolone: A glucocorticoid with the general properties of the corticosteroids. It is the drug of choice for all conditions in which routine systemic corticosteroid therapy is indicated, except adrenal deficiency states.
prednisolone : A glucocorticoid that is prednisone in which the oxo group at position 11 has been reduced to the corresponding beta-hydroxy group. It is a drug metabolite of prednisone.

Menopause: The last menstrual period. Permanent cessation of menses (MENSTRUATION) is usually defined after 6 to 12 months of AMENORRHEA in a woman over 45 years of age. In the United States, menopause generally occurs in women between 48 and 55 years of age.

Research Excerpts

ExcerptRelevanceReference
"This trial was conducted to determine if the reported superiority of tamoxifen (TAM) plus prednisolone (PRDLN) over TAM alone in postmenopausal women with metastatic breast cancer could be corroborated."9.07A double-blind trial of tamoxifen plus prednisolone versus tamoxifen plus placebo in postmenopausal women with metastatic breast cancer. A collaborative trial of the North Central Cancer Treatment Group and Mayo Clinic. ( Etzell, PS; Gerstner, JG; Gesme, DH; Ingle, JN; Krook, JE; Long, HJ; Mailliard, JA; Pfeifle, DM; Schaid, DJ; Windschitl, HE, 1991)
"Serum sex hormone binding globulin (SHBG) was measured in 21 pre and 39 postmenopausal women with advanced breast cancer before treatment and 1, 3, 6, 9 and 12 months after ovarian irradiation or during continuous administration of tamoxifen at a dose of 10 mg twice daily, respectively; some patients received additional prednisolone at a dose of 5 mg twice a day."9.06Effects of prednisolone on sex hormone binding globulin during primary endocrine treatment of advanced breast cancer. ( Bulbrook, RD; Clark, GM; Moore, JW; Rubens, RD; Wang, DY, 1988)
"Various plasma hormones were measured in 13 pre- and 20 post-menopausal women with advanced breast cancer before and for 12 months after ovarian irradiation or during continuous administration of tamoxifen at a dose of 10 mg twice a day, respectively; some patients received additional prednisolone at a dose of 5 mg twice a day."9.05Effect of prednisolone on hormone profiles during primary endocrine treatment of advanced breast cancer. ( Blackburn, AM; Bulbrook, RD; Hoare, SA; Kwa, HG; Rubens, RD; Thomas, BS; Wang, DY, 1984)
"The sex hormones dehydroepiandrosterone sulphate (DHEAS), oestradiol, and sex hormone binding globulin (SHBG) were measured in 185 postmenopausal women (aged 45-65 years) with rheumatoid arthritis (RA) and related to assessments of bone mineral density at the spine and proximal femur."7.68Depressed levels of dehydroepiandrosterone sulphate in postmenopausal women with rheumatoid arthritis but no relation with axial bone density. ( Hall, GM; Perry, LA; Spector, TD, 1993)
" The bioavailability and volume of distribution of prednisolone were unaffected by menopausal status."5.29The effects of menopause and hormone replacement therapies on prednisolone and erythromycin pharmacokinetics. ( Benet, LZ; Harris, RZ; Mroczkowski, P; Tsunoda, SM; Wong, H, 1996)
"This trial was conducted to determine if the reported superiority of tamoxifen (TAM) plus prednisolone (PRDLN) over TAM alone in postmenopausal women with metastatic breast cancer could be corroborated."5.07A double-blind trial of tamoxifen plus prednisolone versus tamoxifen plus placebo in postmenopausal women with metastatic breast cancer. A collaborative trial of the North Central Cancer Treatment Group and Mayo Clinic. ( Etzell, PS; Gerstner, JG; Gesme, DH; Ingle, JN; Krook, JE; Long, HJ; Mailliard, JA; Pfeifle, DM; Schaid, DJ; Windschitl, HE, 1991)
"Serum sex hormone binding globulin (SHBG) was measured in 21 pre and 39 postmenopausal women with advanced breast cancer before treatment and 1, 3, 6, 9 and 12 months after ovarian irradiation or during continuous administration of tamoxifen at a dose of 10 mg twice daily, respectively; some patients received additional prednisolone at a dose of 5 mg twice a day."5.06Effects of prednisolone on sex hormone binding globulin during primary endocrine treatment of advanced breast cancer. ( Bulbrook, RD; Clark, GM; Moore, JW; Rubens, RD; Wang, DY, 1988)
"Various plasma hormones were measured in 13 pre- and 20 post-menopausal women with advanced breast cancer before and for 12 months after ovarian irradiation or during continuous administration of tamoxifen at a dose of 10 mg twice a day, respectively; some patients received additional prednisolone at a dose of 5 mg twice a day."5.05Effect of prednisolone on hormone profiles during primary endocrine treatment of advanced breast cancer. ( Blackburn, AM; Bulbrook, RD; Hoare, SA; Kwa, HG; Rubens, RD; Thomas, BS; Wang, DY, 1984)
"The sex hormones dehydroepiandrosterone sulphate (DHEAS), oestradiol, and sex hormone binding globulin (SHBG) were measured in 185 postmenopausal women (aged 45-65 years) with rheumatoid arthritis (RA) and related to assessments of bone mineral density at the spine and proximal femur."3.68Depressed levels of dehydroepiandrosterone sulphate in postmenopausal women with rheumatoid arthritis but no relation with axial bone density. ( Hall, GM; Perry, LA; Spector, TD, 1993)
"Thirty-one patients with rheumatoid arthritis maintained on prednisolone 5 mg daily for an average period of 9."3.67Prolonged low-dose corticosteroid therapy and osteoporosis in rheumatoid arthritis. ( Hajiroussou, VJ; Webley, M, 1984)
" The studies were performed to examine a possible difference between right and left oviducts, age-related differences, changes due to the menstrual cycle and pregnancy, and the effects of various drugs such as antibiotics, urokinase and corticosteroid (prednisolone)."3.67[Cilium movement of human oviduct]. ( Yamaoka, S, 1987)
"Tamoxifen alone was given to 26 women, and 20 received additional prednisolone."2.67Tamoxifen protects against steroid-induced bone loss. ( Caleffi, M; Chaudary, MA; Fentiman, IS; Fogelman, I; Saad, Z, 1992)
"Seventy patients with breast cancer (stage IIIb--IV) were randomized by an "envelope" method into 2 groups, each including 35 persons."2.64[Combined drug treatment of far-advanced forms of breast cancer]. ( Borisov, AI, 1978)
"Renal biopsy indicated Class V + IV(G)-A lupus nephritis (LN)."1.48Pulmonary lymphangioleimyomatosis and systemic lupus erythematosus in a menopausal woman. ( Hong, H; Li, X; Ma, Z; Wang, M; Yang, R, 2018)
"We conclude that menopause affects the bone turnover in RA as well as in normal controls."1.30The effects of menopausal status and disease activity on biochemical markers of bone metabolism in female patients with rheumatoid arthritis. ( Hoshino, H; Inoue, T; Kushida, K; Miura, M; Miyamoto, S; Suzuki, M; Takahashi, M, 1998)
" Prednisolone therapy in 22 patients (mean dosage 8 mg/day) was associated with reductions in estrone and testosterone levels; however, DHEAS and femoral BMD were also decreased in RA patients who were not receiving corticosteroids."1.27Sex hormone status and osteoporosis in postmenopausal women with rheumatoid arthritis. ( Champion, GD; Eisman, JA; Pocock, NA; Sambrook, PN, 1988)
"Osteoporosis is a common complication of corticosteroid therapy and it is associated with both decreased bone formation and increased bone resorption."1.27Calcium metabolism and osteoporosis in corticosteroid-treated postmenopausal women. ( Hartley, TF; Need, AG; Nordin, BE; Philcox, JC, 1986)

Research

Studies (35)

TimeframeStudies, this research(%)All Research%
pre-199024 (68.57)18.7374
1990's7 (20.00)18.2507
2000's1 (2.86)29.6817
2010's3 (8.57)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Hong, H1
Yang, R1
Li, X1
Wang, M1
Ma, Z1
Tuin, J1
Sanders, JS1
van Beek, AP1
Hoek, A1
Stegeman, CA1
Earnest, BS1
Men, LC1
Sukvinder Kaur, G1
Alias, RB1
Sunita Devi, H1
HEATHER, AJ1
SCHMID, J1
IRVINE, WT1
Brandenburg, VM1
Ketteler, M1
Heussen, N1
Politt, D1
Frank, RD1
Westenfeld, R1
Ittel, TH1
Floege, J1
Blackburn, AM1
Wang, DY3
Bulbrook, RD2
Thomas, BS1
Kwa, HG1
Hoare, SA1
Rubens, RD4
Hajiroussou, VJ1
Webley, M1
Stewart, JF1
King, RJ1
Minton, MJ1
Steiner, R1
Tong, D2
Winter, PJ2
Knight, RK2
Hayward, JL1
Hall, GM1
Perry, LA1
Spector, TD1
Harris, RZ1
Tsunoda, SM1
Mroczkowski, P1
Wong, H1
Benet, LZ2
Suzuki, M1
Takahashi, M1
Miyamoto, S1
Hoshino, H1
Kushida, K1
Miura, M1
Inoue, T1
Smallridge, RC1
Wartofsky, L1
Dimond, RC1
Crilly, RG1
Marshall, DH2
Nordin, BE4
Borisov, AI1
Crilly, R1
Fentiman, IS1
Saad, Z1
Caleffi, M1
Chaudary, MA1
Fogelman, I1
Richards, MA1
Coleman, RE2
Hamsa, R1
Khaled, H1
el Mawla, MG1
Kadry, I1
Hablas, A1
Ramadan, M1
Allen, D1
Ingle, JN1
Mailliard, JA1
Schaid, DJ1
Krook, JE1
Gesme, DH1
Windschitl, HE1
Pfeifle, DM1
Etzell, PS1
Gerstner, JG1
Long, HJ1
Smith, D1
Dewar, JA1
Horobin, JM1
Scott, JS1
Preece, PE1
Hughes, GR1
Sambrook, PN2
Eisman, JA2
Champion, GD2
Pocock, NA2
Gustavson, LE1
Legler, UF1
Tinson, CL1
North, WR1
Montecucco, C1
Baldi, F1
Fortina, A1
Tomassini, G1
Caporali, R1
Cherie-Ligniere, EL1
Fratino, P1
Clark, GM1
Moore, JW1
Need, AG1
Philcox, JC1
Hartley, TF1
Yamaoka, S1
Yeates, MG1
Eberl, S1
Tamaoka, T1
Gagliardi, L1
Skripkin, IuK1
Markin, IIa1
Gallagher, JC1
Aaron, J1
Horsman, A1
Wilkinson, R1
Konoplia, EF1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
CID 0708 - Sex, Aging and Antiretroviral Pharmacokinetics[NCT00666055]11 participants (Actual)Observational2008-03-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for prednisolone and Menopause

ArticleYear
SELECTION AND TREATMENT OF PATIENTS WITH ADVANCED BREAST CANCER.
    Clinical radiology, 1964, Volume: 15

    Topics: Adrenalectomy; Androgens; Breast; Breast Neoplasms; Cortisone; Estrogens; Female; Humans; Hypophysec

1964

Trials

8 trials available for prednisolone and Menopause

ArticleYear
Effect of prednisolone on hormone profiles during primary endocrine treatment of advanced breast cancer.
    Cancer treatment reports, 1984, Volume: 68, Issue:12

    Topics: Breast Neoplasms; Clinical Trials as Topic; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate;

1984
Contribution of prednisolone to the primary endocrine treatment of advanced breast cancer.
    European journal of cancer & clinical oncology, 1982, Volume: 18, Issue:12

    Topics: Adult; Breast Neoplasms; Drug Therapy, Combination; Female; Humans; Menopause; Ovary; Prednisolone;

1982
[Combined drug treatment of far-advanced forms of breast cancer].
    Voprosy onkologii, 1978, Volume: 24, Issue:12

    Topics: Antineoplastic Agents; Breast Neoplasms; Castration; Clinical Trials as Topic; Cyclophosphamide; Dru

1978
Tamoxifen protects against steroid-induced bone loss.
    European journal of cancer (Oxford, England : 1990), 1992, Volume: 28, Issue:2-3

    Topics: Aged; Bone Density; Bone Resorption; Breast Neoplasms; Female; Humans; Menopause; Middle Aged; Predn

1992
A double-blind trial of tamoxifen plus prednisolone versus tamoxifen plus placebo in postmenopausal women with metastatic breast cancer. A collaborative trial of the North Central Cancer Treatment Group and Mayo Clinic.
    Cancer, 1991, Jul-01, Volume: 68, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Body Weight; Breast Neoplasms; Double-Blind Method; Female; Humans;

1991
Meakin adjuvant regimen in premenopausal patients with breast cancer.
    The British journal of surgery, 1990, Volume: 77, Issue:11

    Topics: Adult; Breast Neoplasms; Combined Modality Therapy; Drug Administration Schedule; Female; Humans; Me

1990
Prednisolone improves the response to primary endocrine treatment for advanced breast cancer.
    British journal of cancer, 1988, Volume: 58, Issue:5

    Topics: Adult; Breast Neoplasms; Combined Modality Therapy; Drug Synergism; Female; Humans; Menopause; Middl

1988
Effects of prednisolone on sex hormone binding globulin during primary endocrine treatment of advanced breast cancer.
    Breast cancer research and treatment, 1988, Volume: 11, Issue:1

    Topics: Breast Neoplasms; Combined Modality Therapy; Female; Humans; Menopause; Ovary; Prednisolone; Radioth

1988

Other Studies

26 other studies available for prednisolone and Menopause

ArticleYear
Pulmonary lymphangioleimyomatosis and systemic lupus erythematosus in a menopausal woman.
    BMC nephrology, 2018, 04-18, Volume: 19, Issue:1

    Topics: Anti-Bacterial Agents; Cyclophosphamide; Drug Therapy, Combination; Fatal Outcome; Female; Humans; I

2018
Brief Report: Menopause and Primary Ovarian Insufficiency in Women Treated for Antineutrophil Cytoplasmic Antibody-Associated Vasculitides.
    Arthritis & rheumatology (Hoboken, N.J.), 2016, Volume: 68, Issue:4

    Topics: Adult; Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis; Azathioprine; Case-Control Studie

2016
Chronic hepatitis C infection associated with neuromyelitis optica and antinuclear antibodies.
    The Journal of the Association of Physicians of India, 2010, Volume: 58

    Topics: Anti-Inflammatory Agents; Antibodies, Antinuclear; Hepatitis C Antibodies; Hepatitis C, Chronic; Hum

2010
TREATMENT OF OSTEOPOROSIS WITH AN ANABOLIC COMPOUND AND L-LYSINE.
    Delaware medical journal, 1963, Volume: 35

    Topics: Amino Acids; Anabolic Agents; Appetite; Arthritis; Arthritis, Rheumatoid; Dietary Proteins; Emotions

1963
[CALCIUM THERAPY OF OSTEOPOROSIS. DETERMINATION OF BONE DENSITY AS A CRITERION].
    Schweizerische medizinische Wochenschrift, 1963, Dec-21, Volume: 93

    Topics: Aging; Anabolic Agents; Arthritis; Arthritis, Rheumatoid; Bone and Bones; Bone Density; Calcium; Ger

1963
Lumbar bone mineral density in very long-term renal transplant recipients: impact of circulating sex hormones.
    Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA, 2005, Volume: 16, Issue:12

    Topics: Adult; Aged; Anti-Inflammatory Agents; Bone Density; Dehydroepiandrosterone; Estradiol; Female; Foll

2005
Prolonged low-dose corticosteroid therapy and osteoporosis in rheumatoid arthritis.
    Annals of the rheumatic diseases, 1984, Volume: 43, Issue:1

    Topics: Arthritis, Rheumatoid; Bone and Bones; Female; Humans; Male; Menopause; Middle Aged; Osteoporosis; P

1984
Depressed levels of dehydroepiandrosterone sulphate in postmenopausal women with rheumatoid arthritis but no relation with axial bone density.
    Annals of the rheumatic diseases, 1993, Volume: 52, Issue:3

    Topics: Aged; Arthritis, Rheumatoid; Bone Density; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; E

1993
The effects of menopause and hormone replacement therapies on prednisolone and erythromycin pharmacokinetics.
    Clinical pharmacology and therapeutics, 1996, Volume: 59, Issue:4

    Topics: Adult; Anti-Bacterial Agents; Anti-Inflammatory Agents; Biological Availability; Breath Tests; Cytoc

1996
The effects of menopausal status and disease activity on biochemical markers of bone metabolism in female patients with rheumatoid arthritis.
    British journal of rheumatology, 1998, Volume: 37, Issue:6

    Topics: Adult; Aged; Alkaline Phosphatase; Amino Acids; Anti-Inflammatory Agents, Non-Steroidal; Arthritis,

1998
Inappropriate secretion of thyrotropin: discordance between the suppressive effects of corticosteroids and thyroid hormone.
    The Journal of clinical endocrinology and metabolism, 1979, Volume: 48, Issue:4

    Topics: Acromegaly; Female; Growth Hormone; Humans; Hyperthyroidism; Menopause; Methimazole; Middle Aged; Pr

1979
Metabolic effects of corticosteroid therapy in post-menopausal women.
    Journal of steroid biochemistry, 1979, Volume: 11, Issue:1B

    Topics: Androstenedione; Bone and Bones; Calcium; Creatinine; Dehydroepiandrosterone; Estradiol; Estrone; Fe

1979
The relation between plasma androstenedione and oestrone levels in untreated and corticosteroid-treated post-menopausal women.
    Clinical endocrinology, 1978, Volume: 9, Issue:5

    Topics: Adrenal Cortex Hormones; Adult; Aged; Androstenedione; Castration; Estrone; Female; Humans; Menopaus

1978
Advanced breast cancer in Egyptian women: clinical features and response to endocrine therapy. The Anglo-Egyptian Health Agreement Collaborative Study.
    European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology, 1992, Volume: 18, Issue:3

    Topics: Adult; Breast Neoplasms; Combined Modality Therapy; Egypt; Female; Humans; Mastectomy; Menopause; Mi

1992
A 47-year-old woman presenting with a 20-year history of SLE.
    British journal of rheumatology, 1989, Volume: 28, Issue:4

    Topics: Estrogens; Female; Humans; Lupus Erythematosus, Systemic; Menopause; Middle Aged; Osteoporosis; Pred

1989
Sex hormone status and osteoporosis in postmenopausal women with rheumatoid arthritis.
    Arthritis and rheumatism, 1988, Volume: 31, Issue:8

    Topics: Arthritis, Rheumatoid; Bone and Bones; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Femal

1988
Impairment of prednisolone disposition in women taking oral contraceptives or conjugated estrogens.
    The Journal of clinical endocrinology and metabolism, 1986, Volume: 62, Issue:1

    Topics: Adult; Contraceptives, Oral; Estrogens, Conjugated (USP); Female; Humans; Hydrocortisone; Kinetics;

1986
Serum osteocalcin (bone Gla-protein) following corticosteroid therapy in postmenopausal women with rheumatoid arthritis. Comparison of the effect of prednisone and deflazacort.
    Clinical rheumatology, 1988, Volume: 7, Issue:3

    Topics: Aged; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Calcium-Binding Proteins; Female; Humans; Men

1988
Calcium metabolism and osteoporosis in corticosteroid-treated postmenopausal women.
    Australian and New Zealand journal of medicine, 1986, Volume: 16, Issue:3

    Topics: Aged; Aged, 80 and over; Calcium; Creatinine; Female; Humans; Hydroxyproline; Menopause; Middle Aged

1986
[Cilium movement of human oviduct].
    Nihon Sanka Fujinka Gakkai zasshi, 1987, Volume: 39, Issue:5

    Topics: Adult; Age Factors; Anti-Bacterial Agents; Cilia; Fallopian Tubes; Female; Humans; In Vitro Techniqu

1987
Osteoporosis in rheumatoid arthritis: safety of low dose corticosteroids.
    Annals of the rheumatic diseases, 1986, Volume: 45, Issue:11

    Topics: Adult; Arthritis, Rheumatoid; Bone and Bones; Female; Humans; Menopause; Middle Aged; Osteoporosis;

1986
[Urinary gonadotropin in gynecology with special reference to adrenocortical function].
    Nihon Naibunpi Gakkai zasshi, 1966, May-20, Volume: 42, Issue:2

    Topics: Adrenal Glands; Adrenalectomy; Adrenocorticotropic Hormone; Adult; Aged; Animals; Castration; Clomip

1966
[Gynecologic hormone-dependent tumors].
    Minerva ginecologica, 1974, Volume: 26, Issue:4

    Topics: Androgens; Endometrium; Estrogens; Female; Humans; Menopause; Middle Aged; Ovary; Prednisolone; Uter

1974
[Pathogenesis and treatment of patients with kraurosis vulvae].
    Sovetskaia meditsina, 1974, Issue:11

    Topics: Adult; Aged; Female; Humans; Menopause; Middle Aged; Ointments; Prednisolone; Testosterone; Testoste

1974
Corticosteroid osteoporosis.
    Clinics in endocrinology and metabolism, 1973, Volume: 2, Issue:2

    Topics: Adult; Aged; Aging; Arthritis, Rheumatoid; Asthma; Autoanalysis; Bone and Bones; Calcium; Calcium Ra

1973
[The urinary excretion of estrogens in patients with far advanced breast cancer during treatment with prednisolone].
    Voprosy onkologii, 1968, Volume: 14, Issue:12

    Topics: Adrenal Glands; Breast Neoplasms; Castration; Chromatography; Estradiol; Estriol; Estrogens; Estrone

1968