Compounds > panomifene
Page last updated: 2024-12-10

panomifene

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth

Description

panomifene: structure given in UD 36:24m [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID3033654
CHEMBL ID2105273
SCHEMBL ID62920
MeSH IDM0138319

Synonyms (23)

Synonym
panomifene
gyki-13504
egis-5650
panomifenum [latin]
panomifeno [spanish]
(e)-1,2-diphenyl-1-(4-((2-hydroxyethylamino)ethoxy)phenyl)-3,3,3-trifluoro-1-propene
(e)-2-((2-(p-(3,3,3-trifluoro-1,2-diphenylpropenyl)phenoxy)ethyl)amino)ethanol
ethanol, 2-((2-(4-(3,3,3-trifluoro-1,2-diphenyl-1-propenyl)phenoxy)ethyl)amino)-, (e)-
(e)-2-((2-(4-(3,3,3-trifluoro-1,2-diphenyl-1-propenyl)phenoxy)ethyl)amino)ethanol
panomifene [inn]
2-[2-[4-[(e)-3,3,3-trifluoro-1,2-diphenylprop-1-enyl]phenoxy]ethylamino]ethanol
panomifenum
77599-17-8
gcw5e728oc ,
panomifeno
unii-gcw5e728oc
CHEMBL2105273
SCHEMBL62920
AKOS030631790
(e)-2-((2-(4-(3,3,3-trifluoro-1,2-diphenylprop-1-en-1-yl)phenoxy)ethyl)amino)ethan-1-ol
Q27279037
mhxvdxxarzcvrk-wcwdxbqesa-n
DTXSID401032965

Research Excerpts

Pharmacokinetics

ExcerptReferenceRelevance
" As to the dose escalation, pharmacokinetic studies were carried out at doses of 24, 48 and 96 mg in two volunteers, and 120 mg in one volunteer."( Pharmacokinetics of panomifene in healthy volunteers at phase I/a study.
Bojti, E; Csörgo, M; Drabant, S; Erdélyi-Tóth, V; Gyergyay, F; Klebovich, I; Kralovánszky, J; Pap, E; Számel, I, 1997)		0.62
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (7)

TimeframeStudies, This Drug (%)All Drugs %
pre-19901 (14.29)18.7374
1990's5 (71.43)18.2507
2000's1 (14.29)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials2 (28.57%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other5 (71.43%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
SubstanceRelationship StrengthStudiesTrialsClassesRoles
corticosterone
[no description available]		1.991011beta-hydroxy steroid;
20-oxo steroid;
21-hydroxy steroid;
3-oxo-Delta(4) steroid;
C21-steroid;
glucocorticoid;
primary alpha-hydroxy ketone		human metabolite;
mouse metabolite
palladium
Palladium: A chemical element having an atomic weight of 106.4, atomic number of 46, and the symbol Pd. It is a white, ductile metal resembling platinum, and following it in abundance and importance of applications. It is used in dentistry in the form of gold, silver, and copper alloys.. palladium : Chemical element (nickel group element atom) with atomic number 46.		2.0210metal allergen;
nickel group element atom;
platinum group metal atom
tamoxifen
[no description available]		10.3272stilbenoid;
tertiary amino compound		angiogenesis inhibitor;
antineoplastic agent;
bone density conservation agent;
EC 1.2.3.1 (aldehyde oxidase) inhibitor;
EC 2.7.11.13 (protein kinase C) inhibitor;
estrogen antagonist;
estrogen receptor antagonist;
estrogen receptor modulator
dinoprost
Dinoprost: A naturally occurring prostaglandin that has oxytocic, luteolytic, and abortifacient activities. Due to its vasocontractile properties, the compound has a variety of other biological actions.. prostaglandin F2alpha : A prostaglandins Falpha that is prosta-5,13-dien-1-oic acid substituted by hydroxy groups at positions 9, 11 and 15. It is a naturally occurring prostaglandin used to induce labor.		1.9610monocarboxylic acid;
prostaglandins Falpha		human metabolite;
mouse metabolite
ConditionIndicatedRelationship StrengthStudiesTrials
Breast Cancer
[description not available]		03.7821
Breast Neoplasms
Tumors or cancer of the human BREAST.		03.7821
Menopause
The last menstrual period. Permanent cessation of menses (MENSTRUATION) is usually defined after 6 to 12 months of AMENORRHEA in a woman over 45 years of age. In the United States, menopause generally occurs in women between 48 and 55 years of age.		03.3711
Experimental Mammary Neoplasms
[description not available]		01.9910