nitroglycerin has been researched along with Menopause in 11 studies
Nitroglycerin: A volatile vasodilator which relieves ANGINA PECTORIS by stimulating GUANYLATE CYCLASE and lowering cytosolic calcium. It is also sometimes used for TOCOLYSIS and explosives.
nitroglycerol : A nitrate ester that is glycerol in which nitro group(s) replace the hydrogen(s) attached to one or more of the hydroxy groups.
nitroglycerin : A nitroglycerol that is glycerol in which the hydrogen atoms of all three hydroxy groups are replaced by nitro groups. It acts as a prodrug, releasing nitric oxide to open blood vessels and so alleviate heart pain.
Menopause: The last menstrual period. Permanent cessation of menses (MENSTRUATION) is usually defined after 6 to 12 months of AMENORRHEA in a woman over 45 years of age. In the United States, menopause generally occurs in women between 48 and 55 years of age.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To determine whether uninterrupted administration of transdermal nitroglycerin (NTG) to induce nitrate cross-tolerance decreased the frequency or severity of menopause-related hot flashes." | 9.69 | Efficacy of Continuous Transdermal Nitroglycerin for Treating Hot Flashes by Inducing Nitrate Cross-tolerance in Perimenopausal and Postmenopausal Women: A Randomized Clinical Trial. ( Cummings, SR; Ganz, P; Gibson, CJ; Grady, D; Huang, AJ; Raghunathan, H; Schembri, M; Vittinghoff, E, 2023) |
| "To describe the efficacy and tolerability of continuous nitroglycerin for treatment of hot flashes." | 9.22 | Continuous transdermal nitroglycerin therapy for menopausal hot flashes: a single-arm, dose-escalation trial. ( Cummings, SR; Ganz, P; Grady, D; Huang, AJ; Schembri, M; Vittinghoff, E, 2016) |
| "To determine whether uninterrupted administration of transdermal nitroglycerin (NTG) to induce nitrate cross-tolerance decreased the frequency or severity of menopause-related hot flashes." | 5.69 | Efficacy of Continuous Transdermal Nitroglycerin for Treating Hot Flashes by Inducing Nitrate Cross-tolerance in Perimenopausal and Postmenopausal Women: A Randomized Clinical Trial. ( Cummings, SR; Ganz, P; Gibson, CJ; Grady, D; Huang, AJ; Raghunathan, H; Schembri, M; Vittinghoff, E, 2023) |
| "To describe the efficacy and tolerability of continuous nitroglycerin for treatment of hot flashes." | 5.22 | Continuous transdermal nitroglycerin therapy for menopausal hot flashes: a single-arm, dose-escalation trial. ( Cummings, SR; Ganz, P; Grady, D; Huang, AJ; Schembri, M; Vittinghoff, E, 2016) |
| "Although menopause was not associated with vascular impairment, short-term improvement in vascular function was observed in those using menopausal hormonal therapy." | 1.91 | Effect of menopause and age on vascular impairment. ( Aittokallio, J; Hautajärvi, T; Heinonen, O; Kalleinen, N; Polo, O; Raitakari, O; Riskumäki, M; Saaresranta, T; Vahlberg, T, 2023) |
| "Menopause is associated with impaired arterial endothelial function in Caucasian but not Chinese women." | 1.31 | A comparison of endothelial function in Caucasian and Chinese women before and after the menopause. ( Celermajer, DS; McCrohon, JA; Woo, KS, 2000) |
| "Tamoxifen is a mixed estrogen agonist/antagonist with as yet unexplored effects on vascular function." | 1.30 | Contrasting effects of conjugated estrogens and tamoxifen on dilator responses of atherosclerotic epicardial coronary arteries in nonhuman primates. ( Adams, MR; Honoré, EK; Williams, JK, 1997) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (9.09) | 18.7374 |
| 1990's | 2 (18.18) | 18.2507 |
| 2000's | 5 (45.45) | 29.6817 |
| 2010's | 1 (9.09) | 24.3611 |
| 2020's | 2 (18.18) | 2.80 |
| Authors | Studies |
|---|---|
| Aittokallio, J | 1 |
| Saaresranta, T | 1 |
| Riskumäki, M | 1 |
| Hautajärvi, T | 1 |
| Vahlberg, T | 1 |
| Polo, O | 1 |
| Heinonen, O | 1 |
| Raitakari, O | 1 |
| Kalleinen, N | 1 |
| Huang, AJ | 2 |
| Cummings, SR | 2 |
| Ganz, P | 3 |
| Schembri, M | 2 |
| Raghunathan, H | 1 |
| Vittinghoff, E | 2 |
| Gibson, CJ | 1 |
| Grady, D | 2 |
| Ohmichi, M | 1 |
| Kanda, Y | 1 |
| Hisamoto, K | 1 |
| Morishige, K | 1 |
| Takahashi, K | 1 |
| Sawada, K | 1 |
| Minekawa, R | 1 |
| Tasaka, K | 1 |
| Murata, Y | 1 |
| Zegura, B | 1 |
| Keber, I | 1 |
| Sebestjen, M | 1 |
| Borko, E | 1 |
| Patel, AR | 1 |
| Kuvin, JT | 1 |
| Sliney, KA | 1 |
| Rand, WM | 1 |
| Pandian, NG | 1 |
| Karas, RH | 1 |
| Lieberman, EH | 1 |
| Gerhard, MD | 1 |
| Uehata, A | 1 |
| Walsh, BW | 1 |
| Selwyn, AP | 1 |
| Yeung, AC | 1 |
| Creager, MA | 1 |
| Williams, JK | 1 |
| Honoré, EK | 1 |
| Adams, MR | 1 |
| Majmudar, NG | 1 |
| Robson, SC | 1 |
| Ford, GA | 1 |
| McCrohon, JA | 1 |
| Woo, KS | 1 |
| Celermajer, DS | 1 |
| Ekbom, K | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| [NCT00005681] | 0 participants | Observational | 1989-08-31 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
4 trials available for nitroglycerin and Menopause
| Article | Year |
|---|---|
Efficacy of Continuous Transdermal Nitroglycerin for Treating Hot Flashes by Inducing Nitrate Cross-tolerance in Perimenopausal and Postmenopausal Women: A Randomized Clinical Trial.
Topics: Double-Blind Method; Female; Hot Flashes; Humans; Menopause; Nitrates; Nitroglycerin; Perimenopause; | 2023 |
Continuous transdermal nitroglycerin therapy for menopausal hot flashes: a single-arm, dose-escalation trial.
Topics: Administration, Cutaneous; Adult; Dose-Response Relationship, Drug; Female; Hot Flashes; Humans; Men | 2016 |
Orally and transdermally replaced estradiol improves endothelial function equally in middle-aged women after surgical menopause.
Topics: Administration, Cutaneous; Administration, Oral; Administration, Sublingual; Adnexa Uteri; Antineopl | 2003 |
Estrogen improves endothelium-dependent, flow-mediated vasodilation in postmenopausal women.
Topics: Administration, Oral; Adult; Brachial Artery; Cholesterol; Double-Blind Method; Endothelium, Vascula | 1994 |
7 other studies available for nitroglycerin and Menopause
| Article | Year |
|---|---|
Effect of menopause and age on vascular impairment.
Topics: Brachial Artery; Cardiovascular Diseases; Endothelium, Vascular; Female; Humans; Hypoxia; Menopause; | 2023 |
Rapid changes of flow-mediated dilatation after surgical menopause.
Topics: Adult; Blood Flow Velocity; Brachial Artery; Endothelium, Vascular; Female; Humans; Menopause; Middl | 2003 |
Peripheral vascular endothelial function correlates with exercise capacity in women.
Topics: Adult; Age Factors; Aged; Body Mass Index; Brachial Artery; Endothelium, Vascular; Exercise Test; Ex | 2005 |
Contrasting effects of conjugated estrogens and tamoxifen on dilator responses of atherosclerotic epicardial coronary arteries in nonhuman primates.
Topics: Acetylcholine; Animals; Arteriosclerosis; Body Weight; Cholesterol, HDL; Coronary Circulation; Diet, | 1997 |
Effects of the menopause, gender, and estrogen replacement therapy on vascular nitric oxide activity.
Topics: Arteries; Blood Flow Velocity; Brachial Artery; Enzyme Inhibitors; Estrogen Replacement Therapy; Fem | 2000 |
A comparison of endothelial function in Caucasian and Chinese women before and after the menopause.
Topics: Adult; Aged; Asian People; Australia; Blood Pressure; Brachial Artery; China; Endothelium, Vascular; | 2000 |
A clinical comparison of cluster headache and migraine.
Topics: Adolescent; Adult; Aged; Carotid Arteries; Chronic Disease; Diagnosis, Differential; Ergotamine; Fem | 1970 |