fukinolic acid: also a carboxypeptidase A inhibitor; RN given for (S-(R*,S*))-isomer; structure in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]
| ID Source | ID |
|---|---|
| PubMed CID | 6441059 |
| CHEMBL ID | 487192 |
| CHEBI ID | 177596 |
| SCHEMBL ID | 18371556 |
| MeSH ID | M0298599 |
| Synonym |
|---|
| CHEBI:177596 |
| 50982-40-6 |
| (2r,3s)-2-[(3,4-dihydroxyphenyl)methyl]-3-[(e)-3-(3,4-dihydroxyphenyl)prop-2-enoyl]oxy-2-hydroxybutanedioic acid |
| MEGXP0_000157 |
| ACON1_000044 |
| fukinolic acid |
| NCGC00168846-01 |
| CHEMBL487192 |
| (2r,3s)-2-(3,4-dihydroxybenzyl)-3-(((2e)-3-(3,4-dihydroxyphenyl)-2-propenoyl)oxy)-2-hydroxysuccinic acid |
| unii-oll8du5j30 |
| butanedioic acid, 2-((3,4-dihydroxyphenyl)methyl)-3-(((2e)-3-(3,4-dihydroxyphenyl)-1-oxo-2-propenyl)oxy)-2-hydroxy-, (2r,3s)- |
| oll8du5j30 , |
| butanedioic acid, 2-((3,4-dihydroxyphenyl)methyl)-3-(((2e)-3-(3,4-dihydroxyphenyl)-1-oxo-2-propen-1-yl)oxy)-2-hydroxy-, (2r,3s)- |
| butanedioic acid, 2-((3,4-dihydroxyphenyl)methyl)-3-((3-(3,4-dihydroxyphenyl)-1-oxo-2-propenyl)oxy)-2-hydroxy-, (s-(r*,s*-(e)))- |
| SCHEMBL18371556 |
| ncgc00168846-02!(2r,3s)-2-[(3,4-dihydroxyphenyl)methyl]-3-[(e)-3-(3,4-dihydroxyphenyl)prop-2-enoyl]oxy-2-hydroxybutanedioic acid |
| Q27285721 |
| DTXSID401317189 |
| Class | Description |
|---|---|
| hydroxycinnamic acid | Any member of the class of cinnamic acids carrying one or more hydroxy substituents. |
| [compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res] | |
| Assay ID | Title | Year | Journal | Article |
|---|---|---|---|---|
| AID380094 | Antioxidant activity assessed as DPPH free radical scavenging activity | 2006 | Journal of natural products, Mar, Volume: 69, Issue:3 | Polyphenolic constituents of Actaea racemosa. |
| AID403416 | Binding affinity to 5HT7 receptor | 2005 | Journal of natural products, Aug, Volume: 68, Issue:8 | Cimipronidine, a cyclic guanidine alkaloid from Cimicifuga racemosa. |
| AID477822 | Inhibition of bovine testis hyaluronidase type 4 after 20 mins by modified Morgan-Elson method | 2010 | Journal of natural products, Apr-23, Volume: 73, Issue:4 | Hyaluronidase inhibitors from "Cimicifugae Rhizoma" (a mixture of the rhizomes of Cimicifuga dahurica and C. heracleifolia). |
| [information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||||
| Timeframe | Studies, This Drug (%) | All Drugs % |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (16.67) | 18.2507 |
| 2000's | 5 (41.67) | 29.6817 |
| 2010's | 5 (41.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||
According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be moderate demand-to-supply ratio for research on this compound.
| This Compound (23.86) All Compounds (24.57) |
| Publication Type | This drug (%) | All Drugs (%) |
|---|---|---|
| Trials | 0 (0.00%) | 5.53% |
| Reviews | 0 (0.00%) | 6.00% |
| Case Studies | 0 (0.00%) | 4.05% |
| Observational | 0 (0.00%) | 0.25% |
| Other | 12 (100.00%) | 84.16% |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||