Page last updated: 2024-10-20

pyridoxine and Menopause

pyridoxine has been researched along with Menopause in 13 studies

4,5-bis(hydroxymethyl)-2-methylpyridin-3-ol: structure in first source
vitamin B6 : Any member of the group of pyridines that exhibit biological activity against vitamin B6 deficiency. Vitamin B6 deficiency is associated with microcytic anemia, electroencephalographic abnormalities, dermatitis with cheilosis (scaling on the lips and cracks at the corners of the mouth) and glossitis (swollen tongue), depression and confusion, and weakened immune function. Vitamin B6 consists of the vitamers pyridoxine, pyridoxal, and pyridoxamine and their respective 5'-phosphate esters (and includes their corresponding ionized and salt forms).

Menopause: The last menstrual period. Permanent cessation of menses (MENSTRUATION) is usually defined after 6 to 12 months of AMENORRHEA in a woman over 45 years of age. In the United States, menopause generally occurs in women between 48 and 55 years of age.

Research Excerpts

ExcerptRelevanceReference
"To investigate the incidence of breast cancer and prediagnostic serum levels of folate, B12, and pyridoxal 5'-phosphate (B6), we conducted a nested case-control study using resources from the Washington County (Maryland) serum bank."1.30A prospective study on folate, B12, and pyridoxal 5'-phosphate (B6) and breast cancer. ( Comstock, GW; Helzlsouer, KJ; Hoffman, SC; Nadeau, MR; Selhub, J; Wu, K, 1999)
"The kynurenine load test was introduced to distinguish, in vivo, between abnormal tryptophan metabolism caused by induction of tryptophan oxygenase or by impaired kynureninase function."1.26The kynurenine load test, an adjunct to the tryptophan load test. ( Arend, RA; Brown, RR; Wolf, H, 1980)
"A relative pyridoxine deficiency was found in all of 12 women using conjugated oestrogens unopposed by progestagsns."1.26Disturbance of tryptophan metabolism and its correction during oestrogen treatment in postmenopausal women. ( Bennink, HJ; Haspels, AA; Schreurs, WH, 1978)

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19909 (69.23)18.7374
1990's4 (30.77)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bermond, P1
Wolf, H2
Walter, S1
Brown, RR2
Arend, RA2
Wu, K1
Helzlsouer, KJ1
Comstock, GW1
Hoffman, SC1
Nadeau, MR1
Selhub, J1
de Jong, SC1
Stehouwer, CD1
van den Berg, M1
Kostense, PJ1
Alders, D1
Jakobs, C1
Pals, G1
Rauwerda, JA1
Verhoef, P1
Meleady, R1
Daly, LE1
Graham, IM1
Robinson, K1
Boers, GH1
Haspels, AA2
Bennink, HJ2
Schreurs, WH2
el-Zoghby, SM1
Abdel-Tawab, GA2
Girgis, LH2
Moursi, GE2
Zeitoun, R1
el-Kabariti, HS1
Van Keep, PA1
Pike, S1
Prati, RC1
Cochran, C1
Gorman, MA1
Ashby, J1
Liepa, GU1
Schrijver, J1
Alexieva-Figusch, J1
van Breederode, N1
van Gilse, HA1
Manore, MN1
Leklem, JE1
Walter, MC1
Abdel-Daim, MH1
Kelada, NL1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Folic Acid Clinical Trial (FACT): Biomarker Subgroup Analysis[NCT03981029]51 participants (Actual)Observational2011-12-19Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Other Studies

13 other studies available for pyridoxine and Menopause

ArticleYear
Therapy of side effects of oral contraceptive agents with vitamin B6.
    Acta vitaminologica et enzymologica, 1982, Volume: 4, Issue:1-2

    Topics: Contraceptives, Oral; Contraceptives, Oral, Hormonal; Depressive Disorder; Dose-Response Relationshi

1982
Effect of natural oestrogens on tryptophan metabolism: evidence for interference of oestrogens with kynureninase.
    Scandinavian journal of clinical and laboratory investigation, 1980, Volume: 40, Issue:1

    Topics: Aged; Estradiol; Estriol; Estrogens; Female; Humans; Hydrolases; Kynurenine; Menopause; Middle Aged;

1980
The kynurenine load test, an adjunct to the tryptophan load test.
    Scandinavian journal of clinical and laboratory investigation, 1980, Volume: 40, Issue:1

    Topics: 3-Hydroxyanthranilic Acid; Aged; Female; Humans; Kynurenine; Menopause; Middle Aged; NAD; Pyridoxine

1980
A prospective study on folate, B12, and pyridoxal 5'-phosphate (B6) and breast cancer.
    Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 1999, Volume: 8, Issue:3

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Breast Neoplasms; Case-Control Studies; Cohort Studies;

1999
Determinants of fasting and post-methionine homocysteine levels in families predisposed to hyperhomocysteinemia and premature vascular disease.
    Arteriosclerosis, thrombosis, and vascular biology, 1999, Volume: 19, Issue:5

    Topics: Adult; Age Factors; Amino Acid Substitution; Arteriosclerosis; Body Mass Index; Comorbidity; Fasting

1999
Homocysteine, vitamin status and risk of vascular disease; effects of gender and menopausal status. European COMAC Group.
    European heart journal, 1999, Volume: 20, Issue:17

    Topics: Case-Control Studies; Female; Folic Acid; Homocysteine; Humans; Male; Menopause; Pyridoxine; Risk Fa

1999
Disturbance of tryptophan metabolism and its correction during oestrogen treatment in postmenopausal women.
    Maturitas, 1978, Volume: 1, Issue:1

    Topics: Adult; Aged; Estrogens, Conjugated (USP); Female; Humans; Menopause; Metabolism; Middle Aged; Proges

1978
Functional capacity of the tryptophan-niacin pathway in the premenarchial phase and in the menopausal age.
    The American journal of clinical nutrition, 1975, Volume: 28, Issue:1

    Topics: Adult; Child; Estradiol; Female; Humans; Kynurenine; Male; Menarche; Menopause; Middle Aged; Nicotin

1975
Estrogens and vitamin B6.
    Frontiers of hormone research, 1975, Volume: 3

    Topics: Adolescent; Adult; Contraceptives, Oral; Contraceptives, Oral, Synthetic; Estrogens; Female; Humans;

1975
Lack of effect of vitamin B-6 supplementation on the lipoprotein profile of post-menopausal chronic hemodialysis patients.
    Journal of the American Dietetic Association, 1990, Volume: 90, Issue:7

    Topics: Aged; Arteriosclerosis; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Female; Humans; Lipoprotein

1990
Investigations on the nutritional status of advanced breast cancer patients. The influence of long-term treatment with megestrol acetate or tamoxifen.
    Nutrition and cancer, 1987, Volume: 10, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Breast Neoplasms; Catecholamines; Female; Humans; Megestrol; Megestr

1987
Vitamin B-6 metabolism as affected by exercise in trained and untrained women fed diets differing in carbohydrate and vitamin B-6 content.
    The American journal of clinical nutrition, 1987, Volume: 46, Issue:6

    Topics: Adult; Dietary Carbohydrates; Female; Humans; Menopause; Middle Aged; Physical Exertion; Physical Fi

1987
The influence of sex, age, synthetic oestrogens, progestogens and oral contraceptives on the excretion of urinary tryptophan metabolites.
    Bulletin of the World Health Organization, 1970, Volume: 43, Issue:5

    Topics: Adult; Age Factors; Carboxy-Lyases; Carcinogens; Contraceptives, Oral; Ethinyl Estradiol; Female; Gl

1970