Page last updated: 2024-10-19

melatonin and Menopause

melatonin has been researched along with Menopause in 57 studies

Menopause: The last menstrual period. Permanent cessation of menses (MENSTRUATION) is usually defined after 6 to 12 months of AMENORRHEA in a woman over 45 years of age. In the United States, menopause generally occurs in women between 48 and 55 years of age.

Research Excerpts

ExcerptRelevanceReference
"The aim of our study is to search diagnostic tools for early detection of prenosological melatonin deficiency in postmenopausal women and women in menopausal transition with climacteric syndrome for establishment effective personalized prevention and treatment programs."7.91[Perimenopausal melatonin deficiency syndrome in system of personalized management of quality of life of women with climacteric syndrome.] ( Mamontova, AG; Soloviev, AG; Usoltseva, EN, 2019)
"Although studies have reported the effects of the menstrual cycle on melatonin rhythmicity, none has investigated the effects of menopause on the melatonin rhythm."7.73Effect of menopause on melatonin and alertness rhythms investigated in constant routine conditions. ( Ferns, GA; Hampton, SM; Skene, DJ; Walters, JF, 2005)
"Experimental data from animals suggest a protective role for the pineal hormone melatonin in the etiology of breast cancer, but results from the few retrospective case-control studies that examined the association in humans have been inconsistent."7.72Melatonin and breast cancer: a prospective study. ( Allen, DS; Fentiman, IS; Key, TJ; Travis, RC, 2004)
"Daytime plasma melatonin values were measured by radioimmune assay in 86 patients with breast cancer; 280 assays were done and compared with the clinical status of the patients."7.68Plasma melatonin in patients with breast cancer. ( Falkson, G; Falkson, HC; Meyer, BJ; Rapoport, BL; Steyn, ME, 1990)
"Morning levels of serum melatonin, FSH, LH, prolactin (PRL), progesterone and estradiol were studied by RIA during the ovarian cycle, perimenopause and menopause in 79 healthy women."7.68Relationship between adenohypophyseal and steroid hormones and variations in serum and urinary melatonin levels during the ovarian cycle, perimenopause and menopause in healthy women. ( Acuña, D; Fernandez, B; Malde, JL; Montero, A, 1990)
"We studied the 24-hour plasma melatonin profile in three groups of women: normal individuals, women with breast cancer, and women at high risk for breast cancer, to determine the relationship of plasma melatonin to this malignancy."7.67Plasma melatonin and the hormone-dependency of human breast cancer. ( Bagley, CS; Danforth, DN; Lippman, ME; Mulvihill, JJ; Tamarkin, L, 1985)
"Melatonin is a neurohormone secreted mainly by the pineal gland that controls circadian rhythm, which is primarily regulated by light."6.52Melatonin in aging women. ( Caglar, GS; Gursoy, AY; Kiseli, M, 2015)
"Patients with breast cancer undergoing lumpectomy had significantly disturbed sleep architecture the night after surgery, and these changes were normalised after 2 weeks."5.39Sleep disturbances and changes in urinary 6-sulphatoxymelatonin levels in patients with breast cancer undergoing lumpectomy. ( Gögenur, I; Hansen, MV; Madsen, MT; Rosenberg, J; Wildschiødtz, G, 2013)
"We used the search terms "melatonin" together with "menopause" or "post-menopause" or "peri-menopause" in multiple databases online including PubMed, Web of Science, Embase, Clinical trial, Cochrane Library, and China National Knowledge Infrastructure from the first publication year to October 2020."5.12Effects of exogenous melatonin on sleep quality and menopausal symptoms in menopausal women: a systematic review and meta-analysis of randomized controlled trials. ( Fang, X; Jiang, L; Wang, S; Wu, T; Yi, M; Zhang, X, 2021)
" Endogenous secretion of melatonin decreases with aging across genders, and, among women, menopause is associated with a significant reduction of melatonin levels, affecting sleep."4.93Circadian rhythm and menopause. ( Pines, A, 2016)
"The disparity between the rates of breast cancer in industrialized and less-industrialized regions has led to many hypotheses, including the theory that exposure to light-at-night and/or electromagnetic fields (EMF) may suppress melatonin and that reduced melatonin may increase the risk of breast cancer."4.80Industrialization, electromagnetic fields, and breast cancer risk. ( Kheifets, LI; Matkin, CC, 1999)
"The aim of our study is to search diagnostic tools for early detection of prenosological melatonin deficiency in postmenopausal women and women in menopausal transition with climacteric syndrome for establishment effective personalized prevention and treatment programs."3.91[Perimenopausal melatonin deficiency syndrome in system of personalized management of quality of life of women with climacteric syndrome.] ( Mamontova, AG; Soloviev, AG; Usoltseva, EN, 2019)
"Melatonin and progesterone levels decline during the perimenopause."3.80The effect of estradiol, progesterone, and melatonin on estrous cycling and ovarian aromatase expression in intact female mice. ( Alonso-Gonzalez, C; Bondi, CD; Clafshenkel, WP; Davis, VL; Dodda, BR; Kotlarczyk, MP; Sanchez-Barcelo, E; Witt-Enderby, PA, 2014)
"A protective role of melatonin in the etiology of breast cancer has been suggested."3.74Urinary 6-sulfatoxymelatonin and mammographic density in Japanese women. ( Fujita, H; Hara, T; Kashiki, Y; Matsubara, T; Nagao, Y; Nagata, C; Shibuya, C; Shimizu, H; Yamamoto, S, 2007)
"Although studies have reported the effects of the menstrual cycle on melatonin rhythmicity, none has investigated the effects of menopause on the melatonin rhythm."3.73Effect of menopause on melatonin and alertness rhythms investigated in constant routine conditions. ( Ferns, GA; Hampton, SM; Skene, DJ; Walters, JF, 2005)
"Experimental data from animals suggest a protective role for the pineal hormone melatonin in the etiology of breast cancer, but results from the few retrospective case-control studies that examined the association in humans have been inconsistent."3.72Melatonin and breast cancer: a prospective study. ( Allen, DS; Fentiman, IS; Key, TJ; Travis, RC, 2004)
"Exposure to 60-Hz magnetic fields may increase breast cancer risk by suppressing the normal nocturnal rise in melatonin."3.71Residential magnetic fields, light-at-night, and nocturnal urinary 6-sulfatoxymelatonin concentration in women. ( Chen, C; Davis, S; Kaune, WT; Mirick, DK; Stevens, RG, 2001)
"Daytime plasma melatonin values were measured by radioimmune assay in 86 patients with breast cancer; 280 assays were done and compared with the clinical status of the patients."3.68Plasma melatonin in patients with breast cancer. ( Falkson, G; Falkson, HC; Meyer, BJ; Rapoport, BL; Steyn, ME, 1990)
"We studied the 24-hour plasma melatonin profile in three groups of women: normal individuals, women with breast cancer, and women at high risk for breast cancer, to determine the relationship of plasma melatonin to this malignancy."3.67Plasma melatonin and the hormone-dependency of human breast cancer. ( Bagley, CS; Danforth, DN; Lippman, ME; Mulvihill, JJ; Tamarkin, L, 1985)
"The effect of melatonin on LH and FSH secretion in basal conditions and after stimulation with synthetic LHRH was studied in 3 volunteer normal men and 3 women two to five years after menopause."3.65Effect of melatonin on the basal and stimulated gonadotropin levels in normal men and postmenopausal women. ( Aparicio, NJ; Cramer, C; Debeljuk, L; Fideleff, H; Guitelman, A; Mancini, A, 1976)
"Melatonin treatment improves EEG patterns and subjective sleep quality in postmenopausal women with preexisting sleep impairment."2.72Melatonin and the health of menopausal women: A systematic review. ( Peleg, R; Treister-Goltzman, Y, 2021)
"a persistent condition of past insomnia and aging per se) increase the risk of insomnia during menopause."2.66Insomnia and menopause: a narrative review on mechanisms and treatments. ( Agostoni, EC; Campana, C; Marra, S; Nappi, RE; Nobili, L; Palagini, L; Proserpio, P, 2020)
"Melatonin is a neurohormone secreted mainly by the pineal gland that controls circadian rhythm, which is primarily regulated by light."2.52Melatonin in aging women. ( Caglar, GS; Gursoy, AY; Kiseli, M, 2015)
"Melatonin binding sites have been demonstrated in the central nervous system (mainly in the pars dystalis of the pituitary and hypothalamic suprachiasmatic nucleus) as well as in the reproductive organs, e."2.44[The influence of melatonin on human reproduction]. ( Boczek-Leszczyk, E; Juszczak, M, 2007)
"The same group is at higher risk of insomnia and depression."2.43Menopause related sleep disorders. ( Eichling, PS; Sahni, J, 2005)
"Melatonin profiles are a diagnostic tool to distinguish between several forms of depression, like major depression, winter depression (SAD), unipolar depression, delayed sleep phase syndrome (DSPS)."2.41Melatonin deficiencies in women. ( Herold, J; Rohr, UD, 2002)
"Menopause is associated with a reduction in melatonin which may relate to the changing gonadotropin levels."2.40Melatonin and human reproduction. ( Reiter, RJ, 1998)
"Younger age at menopause has been associated with increased risk of adverse health outcomes, particularly those linked to reproduction."1.51Rotating night shift work and menopausal age. ( Cotterchio, M; Eliassen, AH; Hankinson, SE; Knight, JA; Raboud, J; Rosner, B; Schernhammer, E; Stock, D; Strohmaier, S; Willett, W, 2019)
"The Asian women with TT-genotype and insomnia had a lower levels of melatonin as compared to control at daytime, evening and night."1.48Association of the melatonin circadian rhythms with clock 3111T/C gene polymorphism in Caucasian and Asian menopausal women with insomnia. ( Bairova, TA; Kolesnikova, LI; Madaeva, IM; Semenova, NV; Sholokhov, LF; Zhambalova, RM, 2018)
"Melatonin levels was measured in the saliva 4 times a day (06."1.48Association of 3111T/C Polymorphism of the Clock Gene with Circadian Rhythm of Melatonin in Menopausal Women with Insomnia. ( Bairova, TA; Kalyuzhnaya, OV; Kolesnikova, LI; Madaeva, IM; Rashidova, MA; Semenova, NV; Zhambalova, RM, 2018)
"Patients with breast cancer undergoing lumpectomy had significantly disturbed sleep architecture the night after surgery, and these changes were normalised after 2 weeks."1.39Sleep disturbances and changes in urinary 6-sulphatoxymelatonin levels in patients with breast cancer undergoing lumpectomy. ( Gögenur, I; Hansen, MV; Madsen, MT; Rosenberg, J; Wildschiødtz, G, 2013)
"Intrinsic skin aging is determined primarily by genetic factors and hormonal status."1.32[Intrinsic skin aging. A critical appraisal of the role of hormones]. ( Zouboulis, ChC, 2003)
"The melatonin measures were not consistently related to any of the previously reported hypothalamic-pituitary-adrenal cortical axis measures in these subjects."1.28Neuroendocrine aspects of primary endogenous depression. XI. Serum melatonin measures in patients and matched control subjects. ( Hanada, K; Heist, EK; Lesser, IM; McGeoy, SS; Rubin, RT, 1992)

Research

Studies (57)

TimeframeStudies, this research(%)All Research%
pre-19908 (14.04)18.7374
1990's8 (14.04)18.2507
2000's22 (38.60)29.6817
2010's13 (22.81)24.3611
2020's6 (10.53)2.80

Authors

AuthorsStudies
Usoltseva, EN2
Soloviev, AG2
Mamontova, AG2
Proserpio, P1
Marra, S1
Campana, C1
Agostoni, EC1
Palagini, L1
Nobili, L1
Nappi, RE1
Laudisio, D1
Barrea, L1
Pugliese, G1
Aprano, S1
Castellucci, B1
Savastano, S1
Colao, A1
Muscogiuri, G1
Cipolla-Neto, J1
Amaral, FG1
Soares, JM1
Gallo, CC1
Furtado, A1
Cavaco, JE1
Gonçalves, I1
Santos, CRA1
Quintela, T1
Yi, M1
Wang, S1
Wu, T1
Zhang, X1
Jiang, L1
Fang, X1
Treister-Goltzman, Y1
Peleg, R1
Semenova, NV2
Madaeva, IM2
Bairova, TA2
Zhambalova, RM2
Sholokhov, LF1
Kolesnikova, LI2
Kalyuzhnaya, OV1
Rashidova, MA1
Stock, D1
Knight, JA1
Raboud, J1
Cotterchio, M1
Strohmaier, S1
Willett, W1
Eliassen, AH1
Rosner, B1
Hankinson, SE2
Schernhammer, E1
Hansen, MV1
Madsen, MT1
Wildschiødtz, G1
Rosenberg, J1
Gögenur, I1
Tamura, H1
Takasaki, A1
Taketani, T1
Tanabe, M1
Lee, L1
Tamura, I1
Maekawa, R1
Aasada, H1
Yamagata, Y1
Sugino, N1
Maria, S1
Witt-Enderby, PA2
Bondi, CD1
Alonso-Gonzalez, C1
Clafshenkel, WP1
Kotlarczyk, MP1
Dodda, BR1
Sanchez-Barcelo, E1
Davis, VL1
Gursoy, AY1
Kiseli, M1
Caglar, GS1
Pines, A1
Cagnacci, A2
D'Anna, R1
Santamaria, A1
Giorgianni, G1
Vaiarelli, A1
Gullo, G1
Di Bari, F1
Benvenga, S1
Baeza, I1
Alvarado, C1
Alvarez, P1
Salazar, V1
Castillo, C1
Ariznavarreta, C1
Fdez-Tresguerres, JA1
De la Fuente, M1
Meliska, CJ3
Martínez, LF2
López, AM3
Sorenson, DL2
Nowakowski, S2
Parry, BL4
Zouboulis, ChC1
Travis, RC1
Allen, DS1
Fentiman, IS1
Key, TJ1
Harrod, CG1
Bendok, BR1
Hunt Batjer, H1
Walters, JF1
Hampton, SM1
Ferns, GA1
Skene, DJ2
Bellipanni, G2
DI Marzo, F1
Blasi, F1
Di Marzo, A1
Schernhammer, ES1
Kroenke, CH1
Dowsett, M1
Folkerd, E1
Fernando Martínez, L1
Maurer, EL1
Sorenson, D1
Eichling, PS1
Sahni, J1
Nagata, C1
Matsubara, T1
Hara, T1
Fujita, H1
Nagao, Y1
Yamamoto, S1
Shibuya, C1
Kashiki, Y1
Shimizu, H1
Hauger, RL1
Elliott, JA1
Boczek-Leszczyk, E1
Juszczak, M1
Markantonis, SL1
Tsakalozou, E1
Paraskeva, A1
Staikou, C1
Fassoulaki, A1
Ivanov, SV1
Mal'tseva, LI1
Gafarova, EA1
Garipova, GKh1
Aleem, FA1
Weitzman, ED1
Weinberg, U1
Tapp, E1
Skinner, RG1
Phillips, V1
Bartsch, C1
Seeger, H1
Mück, AO1
Lippert, TH1
Reiter, RJ1
Kheifets, LI1
Matkin, CC1
Sternon, J1
Zanni, AL1
Veneri, MG1
Menozzi, R1
Volpe, A1
Rio, GD1
Bianchi, P1
Pierpaoli, W1
Bulian, D1
Ilyia, E1
Oosthuizen, GM1
Joubert, G1
du Toit, RS1
Davis, S1
Kaune, WT1
Mirick, DK1
Chen, C1
Stevens, RG1
Newton, RP1
Rohr, UD1
Herold, J1
Adami, HO1
Rimsten, A1
Wide, L1
Wetterberg, L1
Halberg, F1
Tarquini, B1
Cagnoni, M1
Haus, E1
Griffith, K1
Kawasaki, T1
Wallach, LA1
Ueno, M1
Uezo, K1
Matsuoka, M1
Kuzel, M1
Halberg, E1
Omae, T1
Fideleff, H1
Aparicio, NJ1
Guitelman, A1
Debeljuk, L1
Mancini, A1
Cramer, C1
Netter, A1
Gayral, MN1
Millet, D1
Rubin, RT1
Heist, EK1
McGeoy, SS1
Hanada, K1
Lesser, IM1
Falkson, G1
Falkson, HC1
Steyn, ME1
Rapoport, BL1
Meyer, BJ1
Fernandez, B1
Malde, JL1
Montero, A1
Acuña, D1
Bojkowski, CJ1
Currie, JE1
Wright, J1
Boulter, PS1
Arendt, J1
Danforth, DN1
Tamarkin, L1
Mulvihill, JJ1
Bagley, CS1
Lippman, ME1
Grishchenko, VI1
Zubkov, GV1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Is Dietary Melatonin Supplementation a Viable Adjunctive Therapy for Chronic Periodontitis? A Preliminary Randomized Clinical Trial.[NCT03368430]Phase 474 participants (Actual)Interventional2016-07-04Completed
Assessment and Augmentation of Lip Appearance in Specific Study Populations[NCT04839692]Phase 437 participants (Actual)Interventional2021-05-07Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Change in Lip Vessel's Thickness

"Pre and post-treatment lip vessel thickness was measured in µm using Optical Coherence Tomography-Angiography imaging. For each age group, pre and post-treatment means were calculated.~The difference between the post and the pre-treatment means is shown below (post-treatment mean - pre-treatment mean)." (NCT04839692)
Timeframe: Day 1 and Day 14

Interventionµm (Mean)
Young Females (21-30 Years Old)0.833
Post Menopausal Females0.360

Lip Fullness Measurement (Measures the Increase of Lip's Size After the Procedure)

"The Lip Fullness Grading Scale was used to measure the size of the lips before and after the procedure in both groups. The result presented below is the difference between the means after and before the procedures for each group.~min value: 0 - very thin lips - worse outcome Max value: 4 - full lips- a better outcome" (NCT04839692)
Timeframe: D1 and D14

Interventionunits on a scale (Mean)
Young Females (21-30 Years Old)1.14
Post Menopausal Females0.78

Wong-Baker FACES Pain Rating Scale

This scale will be used to record the subject's overall pain from the procedure. There are 6 faces ranging from 0=no pain to 10=the worst pain. (NCT04839692)
Timeframe: Day 1

Interventionscore on a scale (Mean)
Young Females (21-30 Years Old)2.9
Post Menopausal Females3.5

Reviews

17 reviews available for melatonin and Menopause

ArticleYear
Insomnia and menopause: a narrative review on mechanisms and treatments.
    Climacteric : the journal of the International Menopause Society, 2020, Volume: 23, Issue:6

    Topics: Antidepressive Agents; Cognitive Behavioral Therapy; Female; Hormone Replacement Therapy; Humans; Me

2020
A practical nutritional guide for the management of sleep disturbances in menopause.
    International journal of food sciences and nutrition, 2021, Volume: 72, Issue:4

    Topics: Adult; Aged; Anxiety; Depression; Diet; Female; Humans; Male; Melatonin; Menopause; Middle Aged; Obe

2021
The Crosstalk between Melatonin and Sex Steroid Hormones.
    Neuroendocrinology, 2022, Volume: 112, Issue:2

    Topics: Animals; Female; Gonadal Steroid Hormones; Gonads; Humans; Male; Melatonin; Menopause; Placenta; Pre

2022
Effects of exogenous melatonin on sleep quality and menopausal symptoms in menopausal women: a systematic review and meta-analysis of randomized controlled trials.
    Menopause (New York, N.Y.), 2021, 03-26, Volume: 28, Issue:6

    Topics: China; Female; Humans; Melatonin; Menopause; Randomized Controlled Trials as Topic; Sleep

2021
Melatonin and the health of menopausal women: A systematic review.
    Journal of pineal research, 2021, Volume: 71, Issue:2

    Topics: Bone Density; Female; Humans; Melatonin; Menopause; Sleep

2021
Melatonin and female reproduction.
    The journal of obstetrics and gynaecology research, 2014, Volume: 40, Issue:1

    Topics: Animals; Circadian Rhythm; Female; Genitalia, Female; Humans; Melatonin; Menopause; Oogenesis; Ovula

2014
Melatonin effects on bone: potential use for the prevention and treatment for osteopenia, osteoporosis, and periodontal disease and for use in bone-grafting procedures.
    Journal of pineal research, 2014, Volume: 56, Issue:2

    Topics: Animals; Bone Diseases, Metabolic; Bone Transplantation; Humans; Melatonin; Menopause; Mice; Osteobl

2014
Melatonin in aging women.
    Climacteric : the journal of the International Menopause Society, 2015, Volume: 18, Issue:6

    Topics: Aging; Animals; Carbohydrate Metabolism; Female; Humans; Lipid Metabolism; Melatonin; Menopause; Neo

2015
Circadian rhythm and menopause.
    Climacteric : the journal of the International Menopause Society, 2016, Volume: 19, Issue:6

    Topics: Aging; Circadian Rhythm; Female; Hot Flashes; Humans; Melatonin; Menopause; Middle Aged; Sex Charact

2016
Sleep, rhythms and women's mood. Part II. Menopause.
    Sleep medicine reviews, 2006, Volume: 10, Issue:3

    Topics: Adult; Circadian Rhythm; Female; Hormone Replacement Therapy; Hot Flashes; Humans; Hydrocortisone; M

2006
Menopause related sleep disorders.
    Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine, 2005, Jul-15, Volume: 1, Issue:3

    Topics: Depression; Estrogen Replacement Therapy; Estrogens; Female; Fibromyalgia; Humans; Hydrocortisone; M

2005
[The influence of melatonin on human reproduction].
    Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego, 2007, Volume: 23, Issue:134

    Topics: Animals; Circadian Rhythm; Female; Gonadotropin-Releasing Hormone; Gonads; Humans; Hypothalamus; Mal

2007
Melatonin and human reproduction.
    Annals of medicine, 1998, Volume: 30, Issue:1

    Topics: Adult; Animals; Circadian Rhythm; Female; Humans; Male; Melatonin; Menopause; Middle Aged; Pineal Gl

1998
Industrialization, electromagnetic fields, and breast cancer risk.
    Environmental health perspectives, 1999, Volume: 107 Suppl 1

    Topics: Breast Neoplasms; Dose-Response Relationship, Radiation; Electromagnetic Fields; Female; Humans; Mal

1999
Chronobiological basis of female-specific mood disorders.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2001, Volume: 25, Issue:5 Suppl

    Topics: Antidepressive Agents, Second-Generation; Chronobiology Phenomena; Cross-Over Studies; Depression, P

2001
Melatonin deficiencies in women.
    Maturitas, 2002, Apr-15, Volume: 41 Suppl 1

    Topics: Breast Neoplasms; Circadian Rhythm; Depression; Female; Humans; Jet Lag Syndrome; Melatonin; Menopau

2002
[Certain results and perspectives of the study of the role of the epiphysis in obstetrics and gynecology (literature survey)].
    Akusherstvo i ginekologiia, 1974, Issue:5

    Topics: Female; Humans; Hypogonadism; Labor, Obstetric; Lactation; Melatonin; Menopause; Menstruation; Ovari

1974

Trials

6 trials available for melatonin and Menopause

ArticleYear
Myo-inositol and melatonin in the menopausal transition.
    Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology, 2017, Volume: 33, Issue:4

    Topics: Body Mass Index; Dietary Supplements; Female; Humans; Inositol; Insulin; Melatonin; Menopause; Middl

2017
Melatonin pharmacokinetics in premenopausal and postmenopausal healthy female volunteers.
    Journal of clinical pharmacology, 2008, Volume: 48, Issue:2

    Topics: Administration, Oral; Adult; Age Factors; Analysis of Variance; Area Under Curve; Body Mass Index; C

2008
The effect of estradiol on the production of melatonin in postmenopausal women.
    International journal of clinical pharmacology and therapeutics, 1995, Volume: 33, Issue:7

    Topics: Administration, Cutaneous; Administration, Oral; Adult; Estradiol; Estrogens; Female; Humans; Melato

1995
Influence of exogenous melatonin on catecholamine levels in postmenopausal women prior and during oestradiol replacement.
    Clinical endocrinology, 2000, Volume: 53, Issue:3

    Topics: Catecholamines; Cold Temperature; Double-Blind Method; Epinephrine; Estradiol; Estrogen Replacement

2000
Effects of melatonin in perimenopausal and menopausal women: a randomized and placebo controlled study.
    Experimental gerontology, 2001, Volume: 36, Issue:2

    Topics: Adult; Affect; Circadian Rhythm; Depression; Double-Blind Method; Female; Follicle Stimulating Hormo

2001
Chronobiological basis of female-specific mood disorders.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2001, Volume: 25, Issue:5 Suppl

    Topics: Antidepressive Agents, Second-Generation; Chronobiology Phenomena; Cross-Over Studies; Depression, P

2001

Other Studies

35 other studies available for melatonin and Menopause

ArticleYear
[Perimenopausal melatonin deficiency syndrome in system of personalized management of quality of life of women with climacteric syndrome.]
    Advances in gerontology = Uspekhi gerontologii, 2019, Volume: 32, Issue:4

    Topics: Adult; Climacteric; Female; Humans; Melatonin; Menopause; Middle Aged; Perimenopause; Precision Medi

2019
[Algorithm for stratification of women for differentiated therapy of menopausal syndrome in combination with perimenopausal melatonin deficiency syndrome.]
    Advances in gerontology = Uspekhi gerontologii, 2020, Volume: 33, Issue:6

    Topics: Algorithms; Female; Humans; Melatonin; Menopause; Perimenopause; Postmenopause; Quality of Life

2020
Association of the melatonin circadian rhythms with clock 3111T/C gene polymorphism in Caucasian and Asian menopausal women with insomnia.
    Chronobiology international, 2018, Volume: 35, Issue:8

    Topics: Asian People; Circadian Rhythm; CLOCK Proteins; Female; Gene Frequency; Genetic Predisposition to Di

2018
Association of 3111T/C Polymorphism of the Clock Gene with Circadian Rhythm of Melatonin in Menopausal Women with Insomnia.
    Bulletin of experimental biology and medicine, 2018, Volume: 165, Issue:3

    Topics: Alleles; Case-Control Studies; Circadian Rhythm; CLOCK Proteins; Female; Gene Expression Regulation;

2018
Rotating night shift work and menopausal age.
    Human reproduction (Oxford, England), 2019, 03-01, Volume: 34, Issue:3

    Topics: Adult; Age Factors; Circadian Rhythm; Female; Humans; Melatonin; Menopause; Menstrual Cycle; Multiva

2019
Sleep disturbances and changes in urinary 6-sulphatoxymelatonin levels in patients with breast cancer undergoing lumpectomy.
    Acta anaesthesiologica Scandinavica, 2013, Volume: 57, Issue:9

    Topics: Adult; Aged; Anesthesia, General; Breast Neoplasms; Fatigue; Female; Humans; Mastectomy, Segmental;

2013
The effect of estradiol, progesterone, and melatonin on estrous cycling and ovarian aromatase expression in intact female mice.
    European journal of obstetrics, gynecology, and reproductive biology, 2014, Volume: 174

    Topics: Animals; Aromatase; Drug Interactions; Estradiol; Estrogen Receptor alpha; Estrous Cycle; Female; Ge

2014
Role of melatonin in circadian rhythm at menopause.
    Climacteric : the journal of the International Menopause Society, 2017, Volume: 20, Issue:2

    Topics: Circadian Rhythm; Female; Humans; Melatonin; Menopause

2017
Improvement of leucocyte functions in ovariectomised aged rats after treatment with growth hormone, melatonin, oestrogens or phyto-oestrogens.
    Journal of reproductive immunology, 2009, Volume: 80, Issue:1-2

    Topics: Age Factors; Aging; Animals; Cell Proliferation; Chemotaxis; Concanavalin A; Cytotoxicity, Immunolog

2009
Relationship of morningness-eveningness questionnaire score to melatonin and sleep timing, body mass index and atypical depressive symptoms in peri- and post-menopausal women.
    Psychiatry research, 2011, Jun-30, Volume: 188, Issue:1

    Topics: Analysis of Variance; Body Mass Index; Circadian Rhythm; Depression; Female; Humans; Melatonin; Meno

2011
[Intrinsic skin aging. A critical appraisal of the role of hormones].
    Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete, 2003, Volume: 54, Issue:9

    Topics: Administration, Topical; Adolescent; Adult; Age Factors; Aged; Androgens; Antioxidants; Chemexfoliat

2003
Melatonin and breast cancer: a prospective study.
    Journal of the National Cancer Institute, 2004, Mar-17, Volume: 96, Issue:6

    Topics: Adult; Aged; Breast Neoplasms; Case-Control Studies; Female; Humans; Matched-Pair Analysis; Melatoni

2004
Interactions between melatonin and estrogen may regulate cerebrovascular function in women: clinical implications for the effective use of HRT during menopause and aging.
    Medical hypotheses, 2005, Volume: 64, Issue:4

    Topics: Cerebrovascular Circulation; Estrogen Replacement Therapy; Estrogens; Female; Humans; Melatonin; Men

2005
Which alternative treatments work?
    Consumer reports, 2005, Volume: 70, Issue:8

    Topics: Back Pain; Chiropractic; Chondroitin; Cimicifuga; Complementary Therapies; Dietary Supplements; Echi

2005
Effect of menopause on melatonin and alertness rhythms investigated in constant routine conditions.
    Chronobiology international, 2005, Volume: 22, Issue:5

    Topics: Adult; Circadian Rhythm; Female; Habits; Humans; Melatonin; Menopause; Middle Aged; Postmenopause; P

2005
Effects of melatonin in perimenopausal and menopausal women: our personal experience.
    Annals of the New York Academy of Sciences, 2005, Volume: 1057

    Topics: Adult; Animals; Estrogens; Female; Follicle Stimulating Hormone; Humans; Luteinizing Hormone; Melato

2005
Urinary 6-sulfatoxymelatonin levels and their correlations with lifestyle factors and steroid hormone levels.
    Journal of pineal research, 2006, Volume: 40, Issue:2

    Topics: Adult; Age Factors; Body Mass Index; Exercise; Female; Gonadal Steroid Hormones; Humans; Life Style;

2006
Urinary 6-sulfatoxymelatonin and mammographic density in Japanese women.
    Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 2007, Volume: 16, Issue:11

    Topics: Adult; Breast Neoplasms; Cross-Sectional Studies; Female; Humans; Japan; Mammography; Melatonin; Men

2007
Increased melatonin and delayed offset in menopausal depression: role of years past menopause, follicle-stimulating hormone, sleep end time, and body mass index.
    The Journal of clinical endocrinology and metabolism, 2008, Volume: 93, Issue:1

    Topics: Body Mass Index; Circadian Rhythm; Depressive Disorder; Estradiol; Female; Follicle Stimulating Horm

2008
[Menopause--a key aspect of aging: role of the pineal gland].
    Advances in gerontology = Uspekhi gerontologii, 2007, Volume: 20, Issue:4

    Topics: Adolescent; Adult; Aging; Female; Humans; Magnetic Resonance Imaging; Male; Melatonin; Menopause; Mi

2007
[The role of melatonin in regulation of gonadal function and its use in the treatment of pathological climax symptoms].
    Advances in gerontology = Uspekhi gerontologii, 2007, Volume: 20, Issue:4

    Topics: Adult; Catecholamines; Female; Hormones; Humans; Hypothalamo-Hypophyseal System; Lipids; Melatonin;

2007
Suppression of basal luteinizing hormone concentrations by melatonin in postmenopausal women.
    Fertility and sterility, 1984, Volume: 42, Issue:6

    Topics: Female; Humans; Hypothalamo-Hypophyseal System; Infusions, Parenteral; Luteinizing Hormone; Melatoni

1984
Radioimmunoassay for melatonin.
    Journal of neural transmission, 1980, Volume: 48, Issue:2

    Topics: Adult; Animals; Female; Humans; Male; Melatonin; Menopause; Middle Aged; Neoplasms; Rabbits; Radioim

1980
[Rejuvenating hormones].
    Revue medicale de Bruxelles, 1999, Volume: 20, Issue:4

    Topics: Antioxidants; Climacteric; Dehydroepiandrosterone; Estrogen Replacement Therapy; Female; Free Radica

1999
A role for melatonin in breast disease and the menopause.
    South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 2001, Volume: 91, Issue:7

    Topics: Adult; Aged; Aged, 80 and over; Breast Diseases; Case-Control Studies; Female; Humans; Melatonin; Me

2001
Residential magnetic fields, light-at-night, and nocturnal urinary 6-sulfatoxymelatonin concentration in women.
    American journal of epidemiology, 2001, Oct-01, Volume: 154, Issue:7

    Topics: Adrenergic beta-Antagonists; Adult; Age Factors; Aged; Alcohol Drinking; Body Mass Index; Breast Neo

2001
Pineal gland, F.S.H., and breast-cancer aetiology.
    Lancet (London, England), 1978, Dec-16, Volume: 2, Issue:8103

    Topics: Aged; Breast Neoplasms; Estrone; Female; Follicle Stimulating Hormone; Humans; Melatonin; Menopause;

1978
Circadian variation in urinary melatonin in clinically healthy women in Japan and the United States of America.
    Experientia, 1979, Mar-15, Volume: 35, Issue:3

    Topics: Adult; Circadian Rhythm; Female; Humans; Japan; Melatonin; Menopause; Middle Aged; Statistics as Top

1979
Effect of melatonin on the basal and stimulated gonadotropin levels in normal men and postmenopausal women.
    The Journal of clinical endocrinology and metabolism, 1976, Volume: 42, Issue:6

    Topics: Adult; Female; Follicle Stimulating Hormone; Gonadotropin-Releasing Hormone; Humans; Luteinizing Hor

1976
[The gonadotropic hypothalamus. Its development from the embryonic period to the menopause].
    Journal de gynecologie, obstetrique et biologie de la reproduction, 1976, Volume: 5, Issue:2

    Topics: Adolescent; Adult; Dopamine; Estradiol; Female; Follicle Stimulating Hormone; Gonadotropin-Releasing

1976
Neuroendocrine aspects of primary endogenous depression. XI. Serum melatonin measures in patients and matched control subjects.
    Archives of general psychiatry, 1992, Volume: 49, Issue:7

    Topics: Adult; Aged; Bipolar Disorder; Circadian Rhythm; Cross-Sectional Studies; Depressive Disorder; Dexam

1992
Plasma melatonin in patients with breast cancer.
    Oncology, 1990, Volume: 47, Issue:5

    Topics: Biomarkers, Tumor; Breast Neoplasms; Female; Humans; Melatonin; Menopause; Middle Aged; Neoplasm Met

1990
Relationship between adenohypophyseal and steroid hormones and variations in serum and urinary melatonin levels during the ovarian cycle, perimenopause and menopause in healthy women.
    Journal of steroid biochemistry, 1990, Volume: 35, Issue:2

    Topics: Adult; Female; Gonadal Steroid Hormones; Humans; Melatonin; Menopause; Menstrual Cycle; Middle Aged;

1990
6-sulphatoxymelatonin production in breast cancer patients.
    Journal of pineal research, 1990, Volume: 8, Issue:3

    Topics: Adult; Aged; Aging; Analysis of Variance; Biopsy; Breast Neoplasms; Circadian Rhythm; Female; Humans

1990
Plasma melatonin and the hormone-dependency of human breast cancer.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1985, Volume: 3, Issue:7

    Topics: Adolescent; Adult; Aged; Breast Neoplasms; Circadian Rhythm; Female; Humans; Melatonin; Menopause; M

1985