Page last updated: 2024-10-29

imipramine and Menopause

imipramine has been researched along with Menopause in 8 studies

Imipramine: The prototypical tricyclic antidepressant. It has been used in major depression, dysthymia, bipolar depression, attention-deficit disorders, agoraphobia, and panic disorders. It has less sedative effect than some other members of this therapeutic group.
imipramine : A dibenzoazepine that is 5H-dibenzo[b,f]azepine substituted by a 3-(dimethylamino)propyl group at the nitrogen atom.

Menopause: The last menstrual period. Permanent cessation of menses (MENSTRUATION) is usually defined after 6 to 12 months of AMENORRHEA in a woman over 45 years of age. In the United States, menopause generally occurs in women between 48 and 55 years of age.

Research Excerpts

ExcerptRelevanceReference
"Subjects diagnosed with DSM-III-R chronic major depressive disorder or double depression (dysthymia with concurrent major depressive episode) were randomly assigned between February 1993 and December 1994 to 12 weeks of double-blind treatment with flexibly-dosed sertraline or imipramine, with crossover to the alternate drug in the absence of response."5.12Acute worsening of chronic depression during a double-blind, randomized clinical trial of antidepressant efficacy: differences by sex and menopausal status. ( Clary, CM; Harvey, AT; Kornstein, SG; Silkey, BS, 2007)
"3H-Imipramine binding was measured in freshly prepared platelet membranes from 47 drug-free major depressives and 46 healthy controls."1.283H-imipramine binding to freshly prepared platelet membranes in depression. ( Davies, SL; Hale, AS; Horton, RW; Katona, CL; Kelly, JS; Kerry, SM; Paykel, ES; Theodorou, AE, 1989)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19903 (37.50)18.7374
1990's0 (0.00)18.2507
2000's4 (50.00)29.6817
2010's1 (12.50)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Vermeiden, M1
van den Broek, WW1
Mulder, PG1
Birkenhäger, TK1
Winterhoff, H1
Spengler, B1
Christoffel, V1
Butterweck, V1
Löhning, A1
Salvatore, S1
Soligo, M1
Proietti, F1
Citterio, S1
Artibani, W1
Milani, R1
Harvey, AT1
Silkey, BS1
Kornstein, SG1
Clary, CM1
Quitkin, FM1
Stewart, JW1
McGrath, PJ1
Pinder, RM1
Brogden, RN1
Speight, TM1
Avery, GS1
Best, NR1
Barlow, DH1
Rees, MP1
Cowen, PJ1
Theodorou, AE1
Katona, CL1
Davies, SL1
Hale, AS1
Kerry, SM1
Horton, RW1
Kelly, JS1
Paykel, ES1

Reviews

2 reviews available for imipramine and Menopause

ArticleYear
Overactive bladder syndrome: considerations in pharmacotherapy and new perspectives.
    European journal of obstetrics, gynecology, and reproductive biology, 2005, Jun-01, Volume: 120, Issue:2

    Topics: Adrenergic alpha-Antagonists; Cholinergic Antagonists; Estrogen Replacement Therapy; Female; Humans;

2005
Doxepin up-to-date: a review of its pharmacological properties and therapeutic efficacy with particular reference to depression.
    Drugs, 1977, Volume: 13, Issue:3

    Topics: Alcoholism; Amitriptyline; Animals; Anxiety; Cardiovascular Diseases; Depression; Doxepin; Drug Inte

1977

Trials

2 trials available for imipramine and Menopause

ArticleYear
Influence of gender and menopausal status on antidepressant treatment response in depressed inpatients.
    Journal of psychopharmacology (Oxford, England), 2010, Volume: 24, Issue:4

    Topics: Adult; Aged; Antidepressive Agents; Depressive Disorder; Double-Blind Method; Female; Fluvoxamine; H

2010
Acute worsening of chronic depression during a double-blind, randomized clinical trial of antidepressant efficacy: differences by sex and menopausal status.
    The Journal of clinical psychiatry, 2007, Volume: 68, Issue:6

    Topics: Adult; Cross-Over Studies; Depressive Disorder, Major; Disease Progression; Double-Blind Method; Dys

2007

Other Studies

4 other studies available for imipramine and Menopause

ArticleYear
Cimicifuga extract BNO 1055: reduction of hot flushes and hints on antidepressant activity.
    Maturitas, 2003, Mar-14, Volume: 44 Suppl 1

    Topics: Animals; Behavior, Animal; Body Temperature; Cimicifuga; Depression; Dose-Response Relationship, Dru

2003
Gender differences in treatment response.
    The American journal of psychiatry, 2001, Volume: 158, Issue:9

    Topics: Antidepressive Agents, Tricyclic; Clinical Trials as Topic; Depressive Disorder; Female; Humans; Imi

2001
Lack of effect of oestradiol implant on platelet imipramine and 5-HT2 receptor binding in menopausal subjects.
    Psychopharmacology, 1989, Volume: 98, Issue:4

    Topics: Adult; Blood Platelets; Drug Implants; Estradiol; Female; Humans; Imipramine; Menopause; Middle Aged

1989
3H-imipramine binding to freshly prepared platelet membranes in depression.
    Psychiatry research, 1989, Volume: 29, Issue:1

    Topics: Adult; Aged; Bipolar Disorder; Blood Platelets; Carrier Proteins; Depressive Disorder; Dexamethasone

1989