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reserpine and Menopause

reserpine has been researched along with Menopause in 19 studies

Reserpine: An alkaloid found in the roots of Rauwolfia serpentina and R. vomitoria. Reserpine inhibits the uptake of norepinephrine into storage vesicles resulting in depletion of catecholamines and serotonin from central and peripheral axon terminals. It has been used as an antihypertensive and an antipsychotic as well as a research tool, but its adverse effects limit its clinical use.
reserpine : An alkaloid found in the roots of Rauwolfia serpentina and R. vomitoria.

Menopause: The last menstrual period. Permanent cessation of menses (MENSTRUATION) is usually defined after 6 to 12 months of AMENORRHEA in a woman over 45 years of age. In the United States, menopause generally occurs in women between 48 and 55 years of age.

Research Excerpts

ExcerptRelevanceReference
"Epidemiological studies of reserpine use and breast cancer have generally found only small increases in breast cancer risk, even after long-term use."7.67Effects of reserpine on prolactin levels and incidence of breast cancer in postmenopausal women. ( Gerkins, VR; Henderson, BE; Krailo, MD; Paganini-Hill, A; Pike, MC; Ross, RK, 1984)
"Although reserpine has an important role in treating patients with hypertension, its appeal was sharply reduced a decade ago when an alleged relationship to breast cancer was reported in case-control studies."7.67Exclusion bias and the false relationship of reserpine and breast cancer. ( Feinstein, AR; Horwitz, RI, 1985)
"Epidemiological studies of reserpine use and breast cancer have generally found only small increases in breast cancer risk, even after long-term use."3.67Effects of reserpine on prolactin levels and incidence of breast cancer in postmenopausal women. ( Gerkins, VR; Henderson, BE; Krailo, MD; Paganini-Hill, A; Pike, MC; Ross, RK, 1984)
"Although reserpine has an important role in treating patients with hypertension, its appeal was sharply reduced a decade ago when an alleged relationship to breast cancer was reported in case-control studies."3.67Exclusion bias and the false relationship of reserpine and breast cancer. ( Feinstein, AR; Horwitz, RI, 1985)
" Intermittently elevated prolactin levels have been noted in some women who subsequently developed breast cancer, but epidemiologic studies of women who have received prolactin-releasing drugs such as reserpine and perphenazine have not disclosed increased risk."3.66Hormones, medications, and cancer. ( Lipsett, MB, 1983)

Research

Studies (19)

TimeframeStudies, this research(%)All Research%
pre-199019 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
MAGGIPINTO, B1
CARRERAS, L1
KUPPERMAN, HS1
BLATT, MH1
VOSBURGH, LF1
CANIS, J1
WETCHLER, B1
HAUSER, A2
WENNER, R3
TRAMONTANO, A1
DI GIOVAN BATTISTA, N1
GIMENEZ, AM1
MASSANO, A1
WILSON, WP1
JOHNSON, JE1
CASTILLO, D1
CARRILLO, F1
CAMPOSSOMELLERA, J1
LEURET, JP1
MORONI, R1
Ross, RK1
Paganini-Hill, A1
Krailo, MD1
Gerkins, VR1
Henderson, BE1
Pike, MC1
Lipsett, MB1
Levin, ML1
Thomas, DB1
Horwitz, RI1
Feinstein, AR1
Soost, HJ1
Ries, P1
Hauser, GA1
Herschberg, AD1

Other Studies

19 other studies available for reserpine and Menopause

ArticleYear
[Rauwolfia reserpine in therapy of essential hypertension in the menopause].
    Minerva ginecologica, 1955, Jul-15, Volume: 7, Issue:13

    Topics: Antihypertensive Agents; Climacteric; Essential Hypertension; Female; Humans; Hypertension; Menopaus

1955
Effect of reserpine, with or without hormonal therapy, upon the female climacteric.
    Journal of the American Geriatrics Society, 1956, Volume: 4, Issue:2

    Topics: Antihypertensive Agents; Climacteric; Female; Gonadal Steroid Hormones; Humans; Menopause; Reserpine

1956
[Serpasil in the management of climacteric dysfunction].
    Gynaecologia. International monthly review of obstetrics and gynecology. Revue internationale mensuelle d'obstetrique et de gynecologie. Monatsschrift fur Geburtshilfe und Gynakologie, 1956, Volume: 142, Issue:5

    Topics: Climacteric; Disease Management; Female; Menopause; Reserpine

1956
[Serpasil in the management of climacteric dysfunction].
    Gynaecologia. International monthly review of obstetrics and gynecology. Revue internationale mensuelle d'obstetrique et de gynecologie. Monatsschrift fur Geburtshilfe und Gynakologie, 1956, Volume: 142, Issue:5

    Topics: Climacteric; Disease Management; Female; Menopause; Reserpine

1956
[Serpasil in the management of climacteric dysfunction].
    Gynaecologia. International monthly review of obstetrics and gynecology. Revue internationale mensuelle d'obstetrique et de gynecologie. Monatsschrift fur Geburtshilfe und Gynakologie, 1956, Volume: 142, Issue:5

    Topics: Climacteric; Disease Management; Female; Menopause; Reserpine

1956
[Serpasil in the management of climacteric dysfunction].
    Gynaecologia. International monthly review of obstetrics and gynecology. Revue internationale mensuelle d'obstetrique et de gynecologie. Monatsschrift fur Geburtshilfe und Gynakologie, 1956, Volume: 142, Issue:5

    Topics: Climacteric; Disease Management; Female; Menopause; Reserpine

1956
[Results and considerations on sedative treatment with a Rauwolfia serpentina alkaloid (reserpine) and antidystonic with sodium glycerophosphates in menopausal disorders].
    Rivista d'ostetricia e ginecologia pratica, 1956, Volume: 38, Issue:12

    Topics: Climacteric; Female; Glycerophosphates; Humans; Hypnotics and Sedatives; Menopause; Rauwolfia; Reser

1956
[Therapeutic effects of drug antagonists; combined reserpine-ritalin (serpatonil)].
    Prensa medica argentina, 1957, Oct-04, Volume: 44, Issue:40

    Topics: Antihypertensive Agents; Climacteric; Female; Menopause; Methylphenidate; Mitral Valve Prolapse; Neu

1957
[Modern treatment of climacteric].
    Prensa medica argentina, 1958, Feb-28, Volume: 45, Issue:9

    Topics: Climacteric; Estrogens; Female; Menopause; Reserpine; Testosterone

1958
[A new preparation in the therapy of female climacteric disorders].
    Minerva ginecologica, 1962, Oct-15, Volume: 14

    Topics: Cardiovascular Diseases; Female; Flavonoids; Hormones; Humans; Menopause; Mental Disorders; Neurolog

1962
THYROID HORMONE AND BRAIN FUNCTION. I. THE EEG IN HYPERTHYROIDISM WITH OBSERVATIONS ON THE EFFECT OF AGE, SEX, AND RESERPINE IN THE PRODUCTION OF ABNORMALITIES.
    Electroencephalography and clinical neurophysiology, 1964, Volume: 16

    Topics: Biomedical Research; Brain; Electroencephalography; Hyperthyroidism; Hyperventilation; Iodine Isotop

1964
[ENDOCRINE MODIFICATIONS WITH THE ADMINISTRATION OF PSYCHOTROPIC AGENTS IN THE MENOPAUSE].
    Medicina, 1964, May-10, Volume: 44

    Topics: Endocrine System; Estriol; Estrogens; Female; Humans; Menopause; Mexico; Nialamide; Physiology; Psyc

1964
[TREATMENT OF MENOPAUSE DISORDERS BY CLIMATERINE].
    Clinique (Paris, France), 1964, Oct-30, Volume: 59

    Topics: Diethylstilbestrol; Drug Therapy; Female; Genital Diseases, Female; Humans; Menopause; Methyltestost

1964
[Climateric hypertension and its treatment with reserpine].
    Rivista d'ostetricia e ginecologia pratica, 1959, Volume: 41

    Topics: Climacteric; Hypertension; Menopause; Reserpine

1959
Effects of reserpine on prolactin levels and incidence of breast cancer in postmenopausal women.
    Cancer research, 1984, Volume: 44, Issue:7

    Topics: Aged; Antihypertensive Agents; Breast Neoplasms; California; Female; Humans; Menopause; Prolactin; R

1984
Hormones, medications, and cancer.
    Cancer, 1983, Jun-15, Volume: 51, Issue:12 Suppl

    Topics: Animals; Breast Neoplasms; Cocarcinogenesis; Drug-Related Side Effects and Adverse Reactions; Epidem

1983
The epidemiology of breast cancer.
    Progress in clinical and biological research, 1977, Volume: 12

    Topics: Adult; Age Factors; Aged; Breast Diseases; Breast Neoplasms; Dietary Fats; Estrogens; Ethnicity; Fem

1977
Exclusion bias and the false relationship of reserpine and breast cancer.
    Archives of internal medicine, 1985, Volume: 145, Issue:10

    Topics: Aged; Breast Neoplasms; Cardiovascular Diseases; Epidemiologic Methods; Female; Humans; Menopause; M

1985
[Secretion and hemorrhage from the breast. Causes and cytodiagnosis].
    Munchener medizinische Wochenschrift (1950), 1969, Apr-25, Volume: 111, Issue:17

    Topics: Adenocarcinoma; Adenofibroma; Adolescent; Adult; Aged; Amenorrhea; Breast; Breast Diseases; Breast N

1969
Editorial: Rauwolfia and breast cancer.
    British medical journal, 1974, Oct-19, Volume: 4, Issue:5937

    Topics: Breast Neoplasms; Depression; Female; Humans; Hypertension; Menopause; Methyldopa; Middle Aged; Phyt

1974
[Reserpine therapy for menopausal trouble (author's transl)].
    Therapeutische Umschau. Revue therapeutique, 1974, Volume: 31, Issue:3

    Topics: Blood Pressure; Climacteric; Female; Humans; Hypertension; Menopause; Middle Aged; Reserpine

1974
[A new treatment of climacteric disorders].
    Gynecologie pratique, 1965, Volume: 16

    Topics: Diethylstilbestrol; Female; Humans; Menopause; Methyltestosterone; Middle Aged; Reserpine

1965