Page last updated: 2024-11-05

thiotepa and Menopause

thiotepa has been researched along with Menopause in 18 studies

Thiotepa: A very toxic alkylating antineoplastic agent also used as an insect sterilant. It causes skin, gastrointestinal, CNS, and bone marrow damage. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), thiotepa may reasonably be anticipated to be a carcinogen (Merck Index, 11th ed).

Menopause: The last menstrual period. Permanent cessation of menses (MENSTRUATION) is usually defined after 6 to 12 months of AMENORRHEA in a woman over 45 years of age. In the United States, menopause generally occurs in women between 48 and 55 years of age.

Research Excerpts

ExcerptRelevanceReference
" The aim of this study was to evaluate the activity and toxicity of the combination of vinorelbine and thiotepa as second-line treatment in patients with metastatic breast cancer."9.08A phase II trial of vinorelbine and thiotepa in metastatic breast cancer. ( Cirulli, S; Cognetti, F; Conte, E; Fabi, A; Savarese, A; Tomao, S; Tonachella, R, 1995)
" The aim of this study was to evaluate the activity and toxicity of the combination of vinorelbine and thiotepa as second-line treatment in patients with metastatic breast cancer."5.08A phase II trial of vinorelbine and thiotepa in metastatic breast cancer. ( Cirulli, S; Cognetti, F; Conte, E; Fabi, A; Savarese, A; Tomao, S; Tonachella, R, 1995)

Research

Studies (18)

TimeframeStudies, this research(%)All Research%
pre-199015 (83.33)18.7374
1990's2 (11.11)18.2507
2000's1 (5.56)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
IRVINE, WT1
Buijs, C1
Rodenhuis, S1
Seynaeve, CM1
van Hoesel, QG1
van der Wall, E1
Smit, WJ1
Nooij, MA1
Voest, E1
Hupperets, P1
TenVergert, EM1
van Tinteren, H1
Willemse, PH1
Mourits, MJ1
Aaronson, NK1
Post, WJ1
de Vries, EG1
Holland, JF1
Fabi, A1
Tonachella, R1
Savarese, A1
Cirulli, S1
Tomao, S1
Conte, E1
Cognetti, F1
Fisher, B5
Slack, N1
Katrych, D1
Wolmark, N1
Suspitsyn, IuV1
Letiagin, VP1
Ivanov, VM1
Orlova, PN1
Bonadonna, G1
Zambetti, M1
Valagussa, P1
Phatak, LV1
Arthur, K1
Sokolova, VD2
Sharoukhova, KS1
Goncharova, MG1
Murav'eva, NI1
Smirnova, KD1
Blokhina, NG2
Karev, NI2
Garin, AM1
Bazhenova, AP1
Balas, AN1
Ravdin, RG1
Ausman, RK1
Slack, NH2
Moore, GE1
Noer, RJ1
Blumenson, LE1
Bross, ID1
Perevodchikova, NI1

Reviews

2 reviews available for thiotepa and Menopause

ArticleYear
SELECTION AND TREATMENT OF PATIENTS WITH ADVANCED BREAST CANCER.
    Clinical radiology, 1964, Volume: 15

    Topics: Adrenalectomy; Androgens; Breast; Breast Neoplasms; Cortisone; Estrogens; Female; Humans; Hypophysec

1964
Adjuvant chemotherapy for node-negative breast cancer patients.
    Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer, 1989, Volume: 115

    Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chlorambucil; Combined Modality Th

1989

Trials

8 trials available for thiotepa and Menopause

ArticleYear
Prospective study of long-term impact of adjuvant high-dose and conventional-dose chemotherapy on health-related quality of life.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2007, Dec-01, Volume: 25, Issue:34

    Topics: Age Factors; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Carboplatin; Chemothe

2007
Adjuvant chemotherapy for breast cancer.
    The Surgical clinics of North America, 1981, Volume: 61, Issue:6

    Topics: Age Factors; Antineoplastic Agents; Breast Neoplasms; Clinical Trials as Topic; Cyclophosphamide; Do

1981
A phase II trial of vinorelbine and thiotepa in metastatic breast cancer.
    Annals of oncology : official journal of the European Society for Medical Oncology, 1995, Volume: 6, Issue:2

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Diseases; Breast Neoplasms; Drug

1995
Ten year follow-up results of patients with carcinoma of the breast in a co-operative clinical trial evaluating surgical adjuvant chemotherapy.
    Surgery, gynecology & obstetrics, 1975, Volume: 140, Issue:4

    Topics: Adult; Aged; Breast Neoplasms; Carcinoma; Clinical Trials as Topic; Female; Follow-Up Studies; Human

1975
Adjuvant chemotherapy for node-negative breast cancer patients.
    Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer, 1989, Volume: 115

    Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chlorambucil; Combined Modality Th

1989
Thio-tepa and endoxan in combined treatment of breast cancer (cooperative trial).
    Radiobiologia, radiotherapia, 1974, Volume: 15, Issue:3

    Topics: Adult; Aged; Breast Neoplasms; Clinical Trials as Topic; Cyclophosphamide; Drug Therapy, Combination

1974
Surgical adjuvant chemotherapy in cancer of the breast: results of a decade of cooperative investigation.
    Annals of surgery, 1968, Volume: 168, Issue:3

    Topics: Adult; Aged; Axilla; Bone Neoplasms; Breast Neoplasms; Clinical Trials as Topic; Female; Fluorouraci

1968
Systemic chemotherapy as an adjuvant to surgery in the treatment of breast cancer.
    Cancer, 1969, Volume: 24, Issue:6

    Topics: Breast Neoplasms; Clinical Trials as Topic; Female; Fluorouracil; Follow-Up Studies; Humans; Mastect

1969

Other Studies

9 other studies available for thiotepa and Menopause

ArticleYear
United States trials of adjuvant therapy.
    World journal of surgery, 1977, Volume: 1, Issue:3

    Topics: Antineoplastic Agents; Breast Neoplasms; Female; Fluorouracil; Humans; Lymphatic Metastasis; Mastect

1977
Management of primary cancer of the breast. New considerations.
    American journal of clinical pathology, 1975, Volume: 64, Issue:6

    Topics: Breast Neoplasms; Female; Humans; Lymphatic Metastasis; Mastectomy; Melphalan; Menopause; Thiotepa

1975
[Treatment of breast cancer in middle-aged and elderly menopausal women].
    Sovetskaia meditsina, 1990, Issue:3

    Topics: Age Factors; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Female; Humans;

1990
A review of treatment of 43 cases of ovarian malignancy with special reference to chemotherapy.
    Journal of the Indian Medical Association, 1972, Feb-16, Volume: 58, Issue:4

    Topics: Adult; Age Factors; Female; Humans; Menopause; Middle Aged; Ovarian Neoplasms; Palliative Care; Pari

1972
Some aspects of chemotherapy in breast carcinomatosis.
    Clinical radiology, 1968, Volume: 19, Issue:3

    Topics: Adrenalectomy; Bone Marrow Diseases; Breast Neoplasms; Carcinoma; Cyclophosphamide; Female; Humans;

1968
[FSH and steroid hormone excretion in breast cancer during chemotherapy].
    Voprosy onkologii, 1972, Volume: 18, Issue:10

    Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Breast Neoplasms; Cyclophosphamide; Estrogens; Female; F

1972
[Results of a comparative study of the efficacy of treatment of early forms of breast neoplasms by different methods].
    Voprosy onkologii, 1973, Volume: 19, Issue:3

    Topics: Adenocarcinoma, Scirrhous; Breast Neoplasms; Female; Humans; Menopause; Middle Aged; Neoplasm Metast

1973
Therapeutic implications from a mathematical model characterizing the course of breast cancer.
    Cancer, 1969, Volume: 24, Issue:5

    Topics: Breast Neoplasms; Female; Fluorouracil; Humans; Lymph Nodes; Lymphatic Metastasis; Male; Mastectomy;

1969
[Comparative evaluation of thiphosphamide, cyclophosphane, methotrexate and 5-fluorouracil in the treatment of breast cancer].
    Vestnik Akademii meditsinskikh nauk SSSR, 1971, Volume: 26, Issue:3

    Topics: Adult; Aged; Breast Neoplasms; Cyclophosphamide; Female; Fluorouracil; Humans; Menopause; Menstruati

1971