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nafoxidine and Menopause

nafoxidine has been researched along with Menopause in 9 studies

Nafoxidine: An estrogen antagonist that has been used in the treatment of breast cancer.

Menopause: The last menstrual period. Permanent cessation of menses (MENSTRUATION) is usually defined after 6 to 12 months of AMENORRHEA in a woman over 45 years of age. In the United States, menopause generally occurs in women between 48 and 55 years of age.

Research Excerpts

ExcerptRelevanceReference
"A randomized clinical trial of nafoxidine, a non-steroidal oestrogen antagonist, and ethinyloestradiol in postmenopausal patients with advanced breast cancer produced objective remissions in 31% of 49 women receiving nafoxidine and in 14% of 49 receiving ethinyloestradiol."9.04Comparative trial of nafoxidine and ethinyloestradiol in advanced breast cancer: an E.O.R.T.C. study. ( Blonk-Van Der Wijst, J; Drochmans, A; Engelsman, E; Gorins, A; Heuson, JC; Maass, H; Michel, J; Nowakowski, H, 1975)
"The synthetic non-steroidal antioestrogen nafoxidine (U-11, 100A) was given by mouth to 52 women with locally advanced or metastatic breast cancer, in 85% of whom the disease had become resistant to, or relapsed after, previous endocrine treatment."7.65Antioestrogens in treatment of breast cancer: value of nafoxidine in 52 advanced cases. ( Bloom, HJ; Boesen, E, 1974)
"A randomized clinical trial of nafoxidine, a non-steroidal oestrogen antagonist, and ethinyloestradiol in postmenopausal patients with advanced breast cancer produced objective remissions in 31% of 49 women receiving nafoxidine and in 14% of 49 receiving ethinyloestradiol."5.04Comparative trial of nafoxidine and ethinyloestradiol in advanced breast cancer: an E.O.R.T.C. study. ( Blonk-Van Der Wijst, J; Drochmans, A; Engelsman, E; Gorins, A; Heuson, JC; Maass, H; Michel, J; Nowakowski, H, 1975)
"Human breast cancer was studied by in vitro techniques on tissue slices and extracts for a specific binding of estradiol and dihydrotestosterone."3.65Steroid hormone receptors in human breast cancer and clinical correlations. ( Engel, B; Maass, H; Nowakowski, H; Stolzenbach, G; Trams, G, 1975)
"The synthetic non-steroidal antioestrogen nafoxidine (U-11, 100A) was given by mouth to 52 women with locally advanced or metastatic breast cancer, in 85% of whom the disease had become resistant to, or relapsed after, previous endocrine treatment."3.65Antioestrogens in treatment of breast cancer: value of nafoxidine in 52 advanced cases. ( Bloom, HJ; Boesen, E, 1974)

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19909 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Maass, H3
Engel, B1
Nowakowski, H3
Stolzenbach, G1
Trams, G1
Görlich, M1
Heise, E1
Tagnon, HJ1
Heuson, JC3
Engelsman, E2
Blonk-Van Der Wijst, J1
Drochmans, A2
Michel, J1
Gorins, A1
Blonk Van Der Wijst, J1
Cheix, F1
Sobrinho, LG1
Bloom, HJ1
Boesen, E1
L'Hermite, M1
Robyn, C1
Rozencweig, M1
Stoll, BA1

Reviews

1 review available for nafoxidine and Menopause

ArticleYear
Antiestrogens in treatment of breast cancer.
    Cancer, 1977, Volume: 39, Issue:6 Suppl

    Topics: Adult; Aged; Breast Neoplasms; Clinical Trials as Topic; Clomiphene; Estrogen Antagonists; Ethinyl E

1977

Trials

4 trials available for nafoxidine and Menopause

ArticleYear
Antiestrogens in treatment of breast cancer.
    Cancer, 1977, Volume: 39, Issue:6 Suppl

    Topics: Adult; Aged; Breast Neoplasms; Clinical Trials as Topic; Clomiphene; Estrogen Antagonists; Ethinyl E

1977
Comparative trial of nafoxidine and ethinyloestradiol in advanced breast cancer: an E.O.R.T.C. study.
    British medical journal, 1975, Jun-28, Volume: 2, Issue:5973

    Topics: Administration, Oral; Adult; Aged; Breast Neoplasms; Clinical Trials as Topic; Ethinyl Estradiol; Fe

1975
Controlled clinical trial of L-dopa and nafoxidine in advanced breast cancer: an E.O.R.T.C. study.
    British medical journal, 1975, Jun-28, Volume: 2, Issue:5973

    Topics: Administration, Oral; Adult; Aged; Breast Neoplasms; Clinical Trials as Topic; Female; Humans; Levod

1975
Letter: Breast cancer regression under oestrogen therapy.
    British medical journal, 1974, Mar-02, Volume: 1, Issue:5904

    Topics: Aged; Breast Neoplasms; Estrogens; Ethinyl Estradiol; Female; Humans; Menopause; Middle Aged; Nafoxi

1974

Other Studies

5 other studies available for nafoxidine and Menopause

ArticleYear
Steroid hormone receptors in human breast cancer and clinical correlations.
    Archiv fur Geschwulstforschung, 1975, Volume: 45, Issue:5

    Topics: Adult; Aged; Breast Neoplasms; Castration; Dihydrotestosterone; Estradiol; Female; Humans; Menopause

1975
Estradiol receptor activity in tissues of human breast cancer.
    Archiv fur Geschwulstforschung, 1975, Volume: 45, Issue:5

    Topics: Androstanols; Breast Neoplasms; Estradiol; Female; Humans; Lymph Nodes; Menopause; Nafoxidine; Progn

1975
Antioestrogens in treatment of breast cancer: value of nafoxidine in 52 advanced cases.
    British medical journal, 1974, Apr-06, Volume: 2, Issue:5909

    Topics: Adult; Aged; Breast Neoplasms; Cataract; Estrogen Antagonists; Female; Humans; Hypophysectomy; Menop

1974
Antioestrogens in treatment of breast cancer.
    British medical journal, 1974, Jun-01, Volume: 2, Issue:5917

    Topics: Antineoplastic Agents; Breast Neoplasms; Dimethylamines; Estrogen Antagonists; Female; Humans; Menop

1974
Letter: Antioestrogens in treatment of breast cancer.
    British medical journal, 1974, May-25, Volume: 2, Issue:5916

    Topics: Breast Neoplasms; Estrogen Antagonists; Female; Humans; Menopause; Nafoxidine; Pyrrolidines

1974