Page last updated: 2024-10-17

lactic acid and Acne

lactic acid has been researched along with Acne in 26 studies

Lactic Acid: A normal intermediate in the fermentation (oxidation, metabolism) of sugar. The concentrated form is used internally to prevent gastrointestinal fermentation. (From Stedman, 26th ed)
2-hydroxypropanoic acid : A 2-hydroxy monocarboxylic acid that is propanoic acid in which one of the alpha-hydrogens is replaced by a hydroxy group.

Research Excerpts

ExcerptRelevanceReference
"To investigate the efficacy and histologic differences of intradermal injection of a filler (poly-d, l-lactic acid, PDLA) using an MFRF device for the treatment of acne scars."9.51Intradermal Injection of Poly-d, l-Lactic Acid Using Microneedle Fractional Radiofrequency for Acne Scars: An Open-Label Prospective Trial. ( Hyeong, JH; Jung, JW; Kim, HS; Kim, KH; Seo, SB, 2022)
" We sought to determine the efficacy and safety of Jessner's solution (JS) in comparison with salicylic acid (SA) 30% in the management of acne vulgaris and postacne hyperpigmentation in patients with colored skin."9.34Efficacy and safety of Jessner's solution peel in comparison with salicylic acid 30% peel in the management of patients with acne vulgaris and postacne hyperpigmentation with skin of color: a randomized, double-blinded, split-face, controlled trial. ( How, KN; Lim, PY; Shamsudin, N; Wan Ahmad Kammal, WSL, 2020)
"5% salicylic acid (SA) solution that does not need to be neutralized in the treatment of acne vulgaris compared to the conventional peeling using Jessner's solution."9.27Comparative study of buffered 50% glycolic acid (pH 3.0) + 0.5% salicylic acid solution vs Jessner's solution in patients with acne vulgaris. ( Dong Hyun, K; Dong Ju, H; In Jae, J; Lee, HJ; Yoon, MS, 2018)
"Injectable poly-L-lactic acid facilitated improvement in hill and valley acne scarring and was well tolerated."9.20A Canadian study of the use of poly-L-lactic acid dermal implant for the treatment of hill and valley acne scarring. ( Mraud, K; Sapra, S; Schupp, R; Stewart, JA, 2015)
"We found that 30% salicylic acid peels were effective for inflammatory acne and more effective than Jessner's solution peels for treating noninflammatory acne."9.17Salicylic acid peels versus Jessner's solution for acne vulgaris: a comparative study. ( Bae, BG; Chung, KY; Lee, JH; Lee, KH; Lee, SH; Lee, SJ; Lee, YS; Park, CO; Shin, H, 2013)
"Many clinicians perform glycolic acid peels for facial acne patients, but there has not been a well-controlled study to compare this new therapy with other conventional modalities."9.09Glycolic acid versus Jessner's solution: which is better for facial acne patients? A randomized prospective clinical trial of split-face model therapy. ( Eun, HC; Kim, JA; Kim, SW; Moon, SE, 1999)
"Retinoids (RC), alpha-hydroxy acids (AHA), and salicylic acid (BHA) treat acne through differing mechanisms of action."7.83Novel retinoid ester in combination with salicylic acid for the treatment of acne. ( Draelos, Z; Lewis, J; McHugh, L; Pellegrino, A; Popescu, L, 2016)
"This report describes a novel use of injectable poly-L-lactic acid (PLLA; Sculptra) for the correction of acne scars in an adult patient."7.75Case study involving use of injectable poly-L-lactic acid (PLLA) for acne scars. ( Palmisano, L; Sadick, NS, 2009)
" Minocycline is a common antibiotic used for the treatment of acne."7.74Severe lactic acidosis secondary to minocycline in a teenager with infectious mononucleosis and mitochondrial myopathy. ( Rison, RA; Zoraster, RM, 2008)
"Salicylic acid (SA) peel is a well-established peeling agent for acne."6.84Jessner's solution vs. 30% salicylic acid peels: a comparative study of the efficacy and safety in mild-to-moderate acne vulgaris. ( Amrani, A; Dayal, S; Jain, VK; Sahu, P, 2017)
"To investigate the efficacy and histologic differences of intradermal injection of a filler (poly-d, l-lactic acid, PDLA) using an MFRF device for the treatment of acne scars."5.51Intradermal Injection of Poly-d, l-Lactic Acid Using Microneedle Fractional Radiofrequency for Acne Scars: An Open-Label Prospective Trial. ( Hyeong, JH; Jung, JW; Kim, HS; Kim, KH; Seo, SB, 2022)
"Acne vulgaris affects up to 80% of people 11 to 30 years of age, and scarring can occur for up to 95% of these patients."5.35Injectable poly-L: -lactic acid: a novel sculpting agent for the treatment of dermal fat atrophy after severe acne. ( Sadove, R, 2009)
" We sought to determine the efficacy and safety of Jessner's solution (JS) in comparison with salicylic acid (SA) 30% in the management of acne vulgaris and postacne hyperpigmentation in patients with colored skin."5.34Efficacy and safety of Jessner's solution peel in comparison with salicylic acid 30% peel in the management of patients with acne vulgaris and postacne hyperpigmentation with skin of color: a randomized, double-blinded, split-face, controlled trial. ( How, KN; Lim, PY; Shamsudin, N; Wan Ahmad Kammal, WSL, 2020)
"Acne scars may negatively impact quality of life."5.34A single-center, open-label study on the use of injectable poly-L-lactic acid for the treatment of moderate to severe scarring from acne or varicella. ( Beer, K, 2007)
"5% salicylic acid (SA) solution that does not need to be neutralized in the treatment of acne vulgaris compared to the conventional peeling using Jessner's solution."5.27Comparative study of buffered 50% glycolic acid (pH 3.0) + 0.5% salicylic acid solution vs Jessner's solution in patients with acne vulgaris. ( Dong Hyun, K; Dong Ju, H; In Jae, J; Lee, HJ; Yoon, MS, 2018)
"Injectable poly-L-lactic acid facilitated improvement in hill and valley acne scarring and was well tolerated."5.20A Canadian study of the use of poly-L-lactic acid dermal implant for the treatment of hill and valley acne scarring. ( Mraud, K; Sapra, S; Schupp, R; Stewart, JA, 2015)
"We found that 30% salicylic acid peels were effective for inflammatory acne and more effective than Jessner's solution peels for treating noninflammatory acne."5.17Salicylic acid peels versus Jessner's solution for acne vulgaris: a comparative study. ( Bae, BG; Chung, KY; Lee, JH; Lee, KH; Lee, SH; Lee, SJ; Lee, YS; Park, CO; Shin, H, 2013)
"Many clinicians perform glycolic acid peels for facial acne patients, but there has not been a well-controlled study to compare this new therapy with other conventional modalities."5.09Glycolic acid versus Jessner's solution: which is better for facial acne patients? A randomized prospective clinical trial of split-face model therapy. ( Eun, HC; Kim, JA; Kim, SW; Moon, SE, 1999)
"The Jessner's-trichloroacetic acid (TCA) peel is a procedure developed by Monheit to produce a safe, effective medium-depth chemical peel for the treatment of photoaged skin, actinic keratoses, and superficial acne scars."4.79The Jessner's-trichloroacetic acid peel. An enhanced medium-depth chemical peel. ( Monheit, GD, 1995)
"Retinoids (RC), alpha-hydroxy acids (AHA), and salicylic acid (BHA) treat acne through differing mechanisms of action."3.83Novel retinoid ester in combination with salicylic acid for the treatment of acne. ( Draelos, Z; Lewis, J; McHugh, L; Pellegrino, A; Popescu, L, 2016)
"The aim of this study was to evaluate a formulation made of poly(lactide-co-glycolide) (PLGA) nanoparticles containing azelaic acid for potential acne treatment."3.80Design of polymeric nanoparticles and its applications as drug delivery systems for acne treatment. ( Fernandes, AS; Martinho, N; Reis, CP; Roberto, A; Rosado, C, 2014)
"This report describes a novel use of injectable poly-L-lactic acid (PLLA; Sculptra) for the correction of acne scars in an adult patient."3.75Case study involving use of injectable poly-L-lactic acid (PLLA) for acne scars. ( Palmisano, L; Sadick, NS, 2009)
" Minocycline is a common antibiotic used for the treatment of acne."3.74Severe lactic acidosis secondary to minocycline in a teenager with infectious mononucleosis and mitochondrial myopathy. ( Rison, RA; Zoraster, RM, 2008)
"Glycolic acid and Jessner's solution are popular superficial chemical peel agents for the treatment of facial acne, and increased sebum secretion is one of the major aetiological factors of acne."3.73Effects of repetitive superficial chemical peels on facial sebum secretion in acne patients. ( Huh, CH; Lee, SH; Park, KC; Youn, SW, 2006)
"Salicylic acid (SA) peel is a well-established peeling agent for acne."2.84Jessner's solution vs. 30% salicylic acid peels: a comparative study of the efficacy and safety in mild-to-moderate acne vulgaris. ( Amrani, A; Dayal, S; Jain, VK; Sahu, P, 2017)
"Acne is one of the most frequent skin disorders that occurs in puberty, but often adults also have acne."2.52[Use of organic acids in acne and skin discolorations therapy]. ( Kapuścińska, A; Nowak, I, 2015)
"Acne vulgaris affects up to 80% of people 11 to 30 years of age, and scarring can occur for up to 95% of these patients."1.35Injectable poly-L: -lactic acid: a novel sculpting agent for the treatment of dermal fat atrophy after severe acne. ( Sadove, R, 2009)
"Acne scars may negatively impact quality of life."1.34A single-center, open-label study on the use of injectable poly-L-lactic acid for the treatment of moderate to severe scarring from acne or varicella. ( Beer, K, 2007)
"Multiple modalities are available for treating acne scars, one of which is chemical peeling."1.31Medium-depth chemical peels in the treatment of acne scars in dark-skinned individuals. ( Al-Sharqi, AI; Al-Waiz, MM, 2002)

Research

Studies (26)

TimeframeStudies, this research(%)All Research%
pre-19902 (7.69)18.7374
1990's2 (7.69)18.2507
2000's7 (26.92)29.6817
2010's13 (50.00)24.3611
2020's2 (7.69)2.80

Authors

AuthorsStudies
Hyeong, JH3
Jung, JW3
Seo, SB3
Kim, HS3
Kim, KH3
Ali, B1
ElMahdy, N1
Elfar, NN1
How, KN1
Lim, PY1
Wan Ahmad Kammal, WSL1
Shamsudin, N1
In Jae, J1
Dong Ju, H1
Dong Hyun, K1
Yoon, MS1
Lee, HJ1
Nofal, E1
Nofal, A1
Gharib, K1
Nasr, M1
Abdelshafy, A1
Elsaid, E1
Reis, CP1
Martinho, N1
Rosado, C1
Fernandes, AS1
Roberto, A1
Ash, C1
Harrison, A1
Drew, S1
Whittall, R1
Kapuścińska, A1
Nowak, I1
Sapra, S1
Stewart, JA1
Mraud, K1
Schupp, R1
Joseph, JH1
Draelos, Z1
Lewis, J1
McHugh, L1
Pellegrino, A1
Popescu, L1
Dayal, S1
Amrani, A1
Sahu, P1
Jain, VK1
Sadove, R1
Sadick, NS1
Palmisano, L1
Sachdeva, S1
Bae, BG1
Park, CO1
Shin, H1
Lee, SH2
Lee, YS1
Lee, SJ1
Chung, KY1
Lee, KH1
Lee, JH1
Monheit, G1
Lowe, NJ1
Huh, CH1
Park, KC1
Youn, SW1
Beer, K1
Zoraster, RM1
Rison, RA1
Prottey, C1
George, D1
Leech, RW1
Black, JG1
Howes, D1
Vickers, CF1
Monheit, GD1
Kim, SW1
Moon, SE1
Kim, JA1
Eun, HC1
Al-Waiz, MM1
Al-Sharqi, AI1
Van Scott, EJ1
Yu, RJ1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
6 Month Double-Blind Randomized Placebo-Controlled Trial to Evaluate the Safety and Efficacy of Small Particle Hyaluronic Acid to Treat Acne Scars Located on the Cheeks and Forehead[NCT02955381]26 participants (Actual)Interventional2017-03-28Terminated (stopped due to Liquidation of Research Department)
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

3 reviews available for lactic acid and Acne

ArticleYear
[Use of organic acids in acne and skin discolorations therapy].
    Postepy higieny i medycyny doswiadczalnej (Online), 2015, Mar-22, Volume: 69

    Topics: Acne Vulgaris; Adolescent; Adult; Child; Dermatitis; Female; Glycolates; Gram-Positive Bacterial Inf

2015
The Case for Synthetic Injectables.
    Facial plastic surgery clinics of North America, 2015, Volume: 23, Issue:4

    Topics: Acne Vulgaris; Biocompatible Materials; Cosmetic Techniques; Dermal Fillers; Durapatite; Esthetics;

2015
The Jessner's-trichloroacetic acid peel. An enhanced medium-depth chemical peel.
    Dermatologic clinics, 1995, Volume: 13, Issue:2

    Topics: Acne Vulgaris; Chemexfoliation; Cicatrix; Drug Combinations; Ethanol; Face; Facial Dermatoses; Human

1995

Trials

10 trials available for lactic acid and Acne

ArticleYear
Intradermal Injection of Poly-d, l-Lactic Acid Using Microneedle Fractional Radiofrequency for Acne Scars: An Open-Label Prospective Trial.
    Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.], 2022, 12-01, Volume: 48, Issue:12

    Topics: Acne Vulgaris; Cicatrix; Humans; Injections, Intradermal; Lactic Acid; Prospective Studies

2022
Intradermal Injection of Poly-d, l-Lactic Acid Using Microneedle Fractional Radiofrequency for Acne Scars: An Open-Label Prospective Trial.
    Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.], 2022, 12-01, Volume: 48, Issue:12

    Topics: Acne Vulgaris; Cicatrix; Humans; Injections, Intradermal; Lactic Acid; Prospective Studies

2022
Intradermal Injection of Poly-d, l-Lactic Acid Using Microneedle Fractional Radiofrequency for Acne Scars: An Open-Label Prospective Trial.
    Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.], 2022, 12-01, Volume: 48, Issue:12

    Topics: Acne Vulgaris; Cicatrix; Humans; Injections, Intradermal; Lactic Acid; Prospective Studies

2022
Intradermal Injection of Poly-d, l-Lactic Acid Using Microneedle Fractional Radiofrequency for Acne Scars: An Open-Label Prospective Trial.
    Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.], 2022, 12-01, Volume: 48, Issue:12

    Topics: Acne Vulgaris; Cicatrix; Humans; Injections, Intradermal; Lactic Acid; Prospective Studies

2022
Microneedling (Dermapen) and Jessner's solution peeling in treatment of atrophic acne scars: a comparative randomized clinical study.
    Journal of cosmetic and laser therapy : official publication of the European Society for Laser Dermatology, 2019, Volume: 21, Issue:6

    Topics: Acne Vulgaris; Chemexfoliation; Cicatrix; Combined Modality Therapy; Cosmetic Techniques; Drug Combi

2019
Efficacy and safety of Jessner's solution peel in comparison with salicylic acid 30% peel in the management of patients with acne vulgaris and postacne hyperpigmentation with skin of color: a randomized, double-blinded, split-face, controlled trial.
    International journal of dermatology, 2020, Volume: 59, Issue:7

    Topics: Acne Vulgaris; Adult; Chemexfoliation; Double-Blind Method; Drug Combinations; Ethanol; Facial Derma

2020
Comparative study of buffered 50% glycolic acid (pH 3.0) + 0.5% salicylic acid solution vs Jessner's solution in patients with acne vulgaris.
    Journal of cosmetic dermatology, 2018, Volume: 17, Issue:5

    Topics: Acne Vulgaris; Adult; Chemexfoliation; Drug Combinations; Drug Therapy, Combination; Esthetics; Etha

2018
Combination chemical peels are more effective than single chemical peel in treatment of mild-to-moderate acne vulgaris: A split face comparative clinical trial.
    Journal of cosmetic dermatology, 2018, Volume: 17, Issue:5

    Topics: Acne Vulgaris; Adult; Analysis of Variance; Chemexfoliation; Drug Combinations; Drug Therapy, Combin

2018
A randomized controlled study for the treatment of acne vulgaris using high-intensity 414 nm solid state diode arrays.
    Journal of cosmetic and laser therapy : official publication of the European Society for Laser Dermatology, 2015, Volume: 17, Issue:4

    Topics: Acne Vulgaris; Adolescent; Adult; Combined Modality Therapy; Cosmetic Techniques; Double-Blind Metho

2015
A Canadian study of the use of poly-L-lactic acid dermal implant for the treatment of hill and valley acne scarring.
    Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.], 2015, Volume: 41, Issue:5

    Topics: Acne Vulgaris; Administration, Cutaneous; Adult; Biocompatible Materials; Canada; Cicatrix; Cosmetic

2015
Jessner's solution vs. 30% salicylic acid peels: a comparative study of the efficacy and safety in mild-to-moderate acne vulgaris.
    Journal of cosmetic dermatology, 2017, Volume: 16, Issue:1

    Topics: Acne Vulgaris; Adolescent; Chemexfoliation; Drug Combinations; Ethanol; Facial Dermatoses; Female; H

2017
Salicylic acid peels versus Jessner's solution for acne vulgaris: a comparative study.
    Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.], 2013, Volume: 39, Issue:2

    Topics: Acne Vulgaris; Adult; Chemexfoliation; Double-Blind Method; Drug Combinations; Ethanol; Face; Humans

2013
Glycolic acid versus Jessner's solution: which is better for facial acne patients? A randomized prospective clinical trial of split-face model therapy.
    Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.], 1999, Volume: 25, Issue:4

    Topics: Acne Vulgaris; Adolescent; Adult; Chemexfoliation; Drug Combinations; Ethanol; Facial Dermatoses; Fe

1999

Other Studies

13 other studies available for lactic acid and Acne

ArticleYear
Design of polymeric nanoparticles and its applications as drug delivery systems for acne treatment.
    Drug development and industrial pharmacy, 2014, Volume: 40, Issue:3

    Topics: Acne Vulgaris; Cell Survival; Chemistry, Pharmaceutical; Delayed-Action Preparations; Dicarboxylic A

2014
Novel retinoid ester in combination with salicylic acid for the treatment of acne.
    Journal of cosmetic dermatology, 2016, Volume: 15, Issue:1

    Topics: Acne Vulgaris; Adult; Anti-Infective Agents; Detergents; Drug Combinations; Female; Humans; Keratoly

2016
Injectable poly-L: -lactic acid: a novel sculpting agent for the treatment of dermal fat atrophy after severe acne.
    Aesthetic plastic surgery, 2009, Volume: 33, Issue:1

    Topics: Acne Vulgaris; Chronic Disease; Cicatrix; Esthetics; Female; Humans; Injections, Intradermal; Lactic

2009
Case study involving use of injectable poly-L-lactic acid (PLLA) for acne scars.
    The Journal of dermatological treatment, 2009, Volume: 20, Issue:5

    Topics: Acne Vulgaris; Cellulose; Cicatrix; Female; Humans; Injections, Intradermal; Lactic Acid; Mannitol;

2009
Lactic acid peeling in superficial acne scarring in Indian skin.
    Journal of cosmetic dermatology, 2010, Volume: 9, Issue:3

    Topics: Acne Vulgaris; Adult; Cicatrix; Female; Humans; India; Keratolytic Agents; Lactic Acid; Pilot Projec

2010
Commentary: salicylic acid peels versus Jessner's solution peels for acne vulgaris: a comparative study.
    Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.], 2013, Volume: 39, Issue:2

    Topics: Acne Vulgaris; Chemexfoliation; Drug Combinations; Ethanol; Humans; Keratolytic Agents; Lactic Acid;

2013
Dispelling the myth: appropriate use of poly-L-lactic acid and clinical considerations.
    Journal of the European Academy of Dermatology and Venereology : JEADV, 2006, Volume: 20 Suppl 1

    Topics: Acne Vulgaris; Biodegradation, Environmental; Cicatrix; Humans; Lactic Acid; Polyesters; Polymers; P

2006
Effects of repetitive superficial chemical peels on facial sebum secretion in acne patients.
    Journal of the European Academy of Dermatology and Venereology : JEADV, 2006, Volume: 20, Issue:8

    Topics: Acne Vulgaris; Adolescent; Adult; Chemexfoliation; Drug Combinations; Ethanol; Facial Dermatoses; Fe

2006
A single-center, open-label study on the use of injectable poly-L-lactic acid for the treatment of moderate to severe scarring from acne or varicella.
    Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.], 2007, Volume: 33 Suppl 2

    Topics: Acne Vulgaris; Adult; Biocompatible Materials; Chickenpox; Cicatrix; Cosmetic Techniques; Face; Fema

2007
Severe lactic acidosis secondary to minocycline in a teenager with infectious mononucleosis and mitochondrial myopathy.
    Clinical neurology and neurosurgery, 2008, Volume: 110, Issue:6

    Topics: Acidosis, Lactic; Acne Vulgaris; Adolescent; Anti-Bacterial Agents; DNA, Mitochondrial; Female; Huma

2008
The mode of action of ethyl lactate as a treatment for acne.
    The British journal of dermatology, 1984, Volume: 110, Issue:4

    Topics: Acne Vulgaris; Adolescent; Adult; Animals; Ethanol; Female; Humans; Hydrogen-Ion Concentration; Lact

1984
Medium-depth chemical peels in the treatment of acne scars in dark-skinned individuals.
    Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.], 2002, Volume: 28, Issue:5

    Topics: Acne Vulgaris; Adolescent; Adult; Caustics; Chemexfoliation; Cicatrix; Drug Combinations; Drug Thera

2002
Alpha hydroxy acids: procedures for use in clinical practice.
    Cutis, 1989, Volume: 43, Issue:3

    Topics: Acne Vulgaris; Administration, Topical; Glycolates; Humans; Ichthyosis; Keratosis; Lactates; Lactic

1989