Page last updated: 2024-10-17
lactic acid and Acne
lactic acid has been researched along with Acne in 26 studies
Lactic Acid: A normal intermediate in the fermentation (oxidation, metabolism) of sugar. The concentrated form is used internally to prevent gastrointestinal fermentation. (From Stedman, 26th ed)
2-hydroxypropanoic acid : A 2-hydroxy monocarboxylic acid that is propanoic acid in which one of the alpha-hydrogens is replaced by a hydroxy group.
Research Excerpts
| Excerpt | Relevance | Reference |
|---|---|---|
| "To investigate the efficacy and histologic differences of intradermal injection of a filler (poly-d, l-lactic acid, PDLA) using an MFRF device for the treatment of acne scars." | 9.51 | Intradermal Injection of Poly-d, l-Lactic Acid Using Microneedle Fractional Radiofrequency for Acne Scars: An Open-Label Prospective Trial. ( Hyeong, JH; Jung, JW; Kim, HS; Kim, KH; Seo, SB, 2022) |
| " We sought to determine the efficacy and safety of Jessner's solution (JS) in comparison with salicylic acid (SA) 30% in the management of acne vulgaris and postacne hyperpigmentation in patients with colored skin." | 9.34 | Efficacy and safety of Jessner's solution peel in comparison with salicylic acid 30% peel in the management of patients with acne vulgaris and postacne hyperpigmentation with skin of color: a randomized, double-blinded, split-face, controlled trial. ( How, KN; Lim, PY; Shamsudin, N; Wan Ahmad Kammal, WSL, 2020) |
| "5% salicylic acid (SA) solution that does not need to be neutralized in the treatment of acne vulgaris compared to the conventional peeling using Jessner's solution." | 9.27 | Comparative study of buffered 50% glycolic acid (pH 3.0) + 0.5% salicylic acid solution vs Jessner's solution in patients with acne vulgaris. ( Dong Hyun, K; Dong Ju, H; In Jae, J; Lee, HJ; Yoon, MS, 2018) |
| "Injectable poly-L-lactic acid facilitated improvement in hill and valley acne scarring and was well tolerated." | 9.20 | A Canadian study of the use of poly-L-lactic acid dermal implant for the treatment of hill and valley acne scarring. ( Mraud, K; Sapra, S; Schupp, R; Stewart, JA, 2015) |
| "We found that 30% salicylic acid peels were effective for inflammatory acne and more effective than Jessner's solution peels for treating noninflammatory acne." | 9.17 | Salicylic acid peels versus Jessner's solution for acne vulgaris: a comparative study. ( Bae, BG; Chung, KY; Lee, JH; Lee, KH; Lee, SH; Lee, SJ; Lee, YS; Park, CO; Shin, H, 2013) |
| "Many clinicians perform glycolic acid peels for facial acne patients, but there has not been a well-controlled study to compare this new therapy with other conventional modalities." | 9.09 | Glycolic acid versus Jessner's solution: which is better for facial acne patients? A randomized prospective clinical trial of split-face model therapy. ( Eun, HC; Kim, JA; Kim, SW; Moon, SE, 1999) |
| "Retinoids (RC), alpha-hydroxy acids (AHA), and salicylic acid (BHA) treat acne through differing mechanisms of action." | 7.83 | Novel retinoid ester in combination with salicylic acid for the treatment of acne. ( Draelos, Z; Lewis, J; McHugh, L; Pellegrino, A; Popescu, L, 2016) |
| "This report describes a novel use of injectable poly-L-lactic acid (PLLA; Sculptra) for the correction of acne scars in an adult patient." | 7.75 | Case study involving use of injectable poly-L-lactic acid (PLLA) for acne scars. ( Palmisano, L; Sadick, NS, 2009) |
| " Minocycline is a common antibiotic used for the treatment of acne." | 7.74 | Severe lactic acidosis secondary to minocycline in a teenager with infectious mononucleosis and mitochondrial myopathy. ( Rison, RA; Zoraster, RM, 2008) |
| "Salicylic acid (SA) peel is a well-established peeling agent for acne." | 6.84 | Jessner's solution vs. 30% salicylic acid peels: a comparative study of the efficacy and safety in mild-to-moderate acne vulgaris. ( Amrani, A; Dayal, S; Jain, VK; Sahu, P, 2017) |
| "To investigate the efficacy and histologic differences of intradermal injection of a filler (poly-d, l-lactic acid, PDLA) using an MFRF device for the treatment of acne scars." | 5.51 | Intradermal Injection of Poly-d, l-Lactic Acid Using Microneedle Fractional Radiofrequency for Acne Scars: An Open-Label Prospective Trial. ( Hyeong, JH; Jung, JW; Kim, HS; Kim, KH; Seo, SB, 2022) |
| "Acne vulgaris affects up to 80% of people 11 to 30 years of age, and scarring can occur for up to 95% of these patients." | 5.35 | Injectable poly-L: -lactic acid: a novel sculpting agent for the treatment of dermal fat atrophy after severe acne. ( Sadove, R, 2009) |
| " We sought to determine the efficacy and safety of Jessner's solution (JS) in comparison with salicylic acid (SA) 30% in the management of acne vulgaris and postacne hyperpigmentation in patients with colored skin." | 5.34 | Efficacy and safety of Jessner's solution peel in comparison with salicylic acid 30% peel in the management of patients with acne vulgaris and postacne hyperpigmentation with skin of color: a randomized, double-blinded, split-face, controlled trial. ( How, KN; Lim, PY; Shamsudin, N; Wan Ahmad Kammal, WSL, 2020) |
| "Acne scars may negatively impact quality of life." | 5.34 | A single-center, open-label study on the use of injectable poly-L-lactic acid for the treatment of moderate to severe scarring from acne or varicella. ( Beer, K, 2007) |
| "5% salicylic acid (SA) solution that does not need to be neutralized in the treatment of acne vulgaris compared to the conventional peeling using Jessner's solution." | 5.27 | Comparative study of buffered 50% glycolic acid (pH 3.0) + 0.5% salicylic acid solution vs Jessner's solution in patients with acne vulgaris. ( Dong Hyun, K; Dong Ju, H; In Jae, J; Lee, HJ; Yoon, MS, 2018) |
| "Injectable poly-L-lactic acid facilitated improvement in hill and valley acne scarring and was well tolerated." | 5.20 | A Canadian study of the use of poly-L-lactic acid dermal implant for the treatment of hill and valley acne scarring. ( Mraud, K; Sapra, S; Schupp, R; Stewart, JA, 2015) |
| "We found that 30% salicylic acid peels were effective for inflammatory acne and more effective than Jessner's solution peels for treating noninflammatory acne." | 5.17 | Salicylic acid peels versus Jessner's solution for acne vulgaris: a comparative study. ( Bae, BG; Chung, KY; Lee, JH; Lee, KH; Lee, SH; Lee, SJ; Lee, YS; Park, CO; Shin, H, 2013) |
| "Many clinicians perform glycolic acid peels for facial acne patients, but there has not been a well-controlled study to compare this new therapy with other conventional modalities." | 5.09 | Glycolic acid versus Jessner's solution: which is better for facial acne patients? A randomized prospective clinical trial of split-face model therapy. ( Eun, HC; Kim, JA; Kim, SW; Moon, SE, 1999) |
| "The Jessner's-trichloroacetic acid (TCA) peel is a procedure developed by Monheit to produce a safe, effective medium-depth chemical peel for the treatment of photoaged skin, actinic keratoses, and superficial acne scars." | 4.79 | The Jessner's-trichloroacetic acid peel. An enhanced medium-depth chemical peel. ( Monheit, GD, 1995) |
| "Retinoids (RC), alpha-hydroxy acids (AHA), and salicylic acid (BHA) treat acne through differing mechanisms of action." | 3.83 | Novel retinoid ester in combination with salicylic acid for the treatment of acne. ( Draelos, Z; Lewis, J; McHugh, L; Pellegrino, A; Popescu, L, 2016) |
| "The aim of this study was to evaluate a formulation made of poly(lactide-co-glycolide) (PLGA) nanoparticles containing azelaic acid for potential acne treatment." | 3.80 | Design of polymeric nanoparticles and its applications as drug delivery systems for acne treatment. ( Fernandes, AS; Martinho, N; Reis, CP; Roberto, A; Rosado, C, 2014) |
| "This report describes a novel use of injectable poly-L-lactic acid (PLLA; Sculptra) for the correction of acne scars in an adult patient." | 3.75 | Case study involving use of injectable poly-L-lactic acid (PLLA) for acne scars. ( Palmisano, L; Sadick, NS, 2009) |
| " Minocycline is a common antibiotic used for the treatment of acne." | 3.74 | Severe lactic acidosis secondary to minocycline in a teenager with infectious mononucleosis and mitochondrial myopathy. ( Rison, RA; Zoraster, RM, 2008) |
| "Glycolic acid and Jessner's solution are popular superficial chemical peel agents for the treatment of facial acne, and increased sebum secretion is one of the major aetiological factors of acne." | 3.73 | Effects of repetitive superficial chemical peels on facial sebum secretion in acne patients. ( Huh, CH; Lee, SH; Park, KC; Youn, SW, 2006) |
| "Salicylic acid (SA) peel is a well-established peeling agent for acne." | 2.84 | Jessner's solution vs. 30% salicylic acid peels: a comparative study of the efficacy and safety in mild-to-moderate acne vulgaris. ( Amrani, A; Dayal, S; Jain, VK; Sahu, P, 2017) |
| "Acne is one of the most frequent skin disorders that occurs in puberty, but often adults also have acne." | 2.52 | [Use of organic acids in acne and skin discolorations therapy]. ( Kapuścińska, A; Nowak, I, 2015) |
| "Acne vulgaris affects up to 80% of people 11 to 30 years of age, and scarring can occur for up to 95% of these patients." | 1.35 | Injectable poly-L: -lactic acid: a novel sculpting agent for the treatment of dermal fat atrophy after severe acne. ( Sadove, R, 2009) |
| "Acne scars may negatively impact quality of life." | 1.34 | A single-center, open-label study on the use of injectable poly-L-lactic acid for the treatment of moderate to severe scarring from acne or varicella. ( Beer, K, 2007) |
| "Multiple modalities are available for treating acne scars, one of which is chemical peeling." | 1.31 | Medium-depth chemical peels in the treatment of acne scars in dark-skinned individuals. ( Al-Sharqi, AI; Al-Waiz, MM, 2002) |
Research
Studies (26)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (7.69) | 18.7374 |
| 1990's | 2 (7.69) | 18.2507 |
| 2000's | 7 (26.92) | 29.6817 |
| 2010's | 13 (50.00) | 24.3611 |
| 2020's | 2 (7.69) | 2.80 |
Authors
| Authors | Studies |
|---|---|
| Hyeong, JH | 3 |
| Jung, JW | 3 |
| Seo, SB | 3 |
| Kim, HS | 3 |
| Kim, KH | 3 |
| Ali, B | 1 |
| ElMahdy, N | 1 |
| Elfar, NN | 1 |
| How, KN | 1 |
| Lim, PY | 1 |
| Wan Ahmad Kammal, WSL | 1 |
| Shamsudin, N | 1 |
| In Jae, J | 1 |
| Dong Ju, H | 1 |
| Dong Hyun, K | 1 |
| Yoon, MS | 1 |
| Lee, HJ | 1 |
| Nofal, E | 1 |
| Nofal, A | 1 |
| Gharib, K | 1 |
| Nasr, M | 1 |
| Abdelshafy, A | 1 |
| Elsaid, E | 1 |
| Reis, CP | 1 |
| Martinho, N | 1 |
| Rosado, C | 1 |
| Fernandes, AS | 1 |
| Roberto, A | 1 |
| Ash, C | 1 |
| Harrison, A | 1 |
| Drew, S | 1 |
| Whittall, R | 1 |
| Kapuścińska, A | 1 |
| Nowak, I | 1 |
| Sapra, S | 1 |
| Stewart, JA | 1 |
| Mraud, K | 1 |
| Schupp, R | 1 |
| Joseph, JH | 1 |
| Draelos, Z | 1 |
| Lewis, J | 1 |
| McHugh, L | 1 |
| Pellegrino, A | 1 |
| Popescu, L | 1 |
| Dayal, S | 1 |
| Amrani, A | 1 |
| Sahu, P | 1 |
| Jain, VK | 1 |
| Sadove, R | 1 |
| Sadick, NS | 1 |
| Palmisano, L | 1 |
| Sachdeva, S | 1 |
| Bae, BG | 1 |
| Park, CO | 1 |
| Shin, H | 1 |
| Lee, SH | 2 |
| Lee, YS | 1 |
| Lee, SJ | 1 |
| Chung, KY | 1 |
| Lee, KH | 1 |
| Lee, JH | 1 |
| Monheit, G | 1 |
| Lowe, NJ | 1 |
| Huh, CH | 1 |
| Park, KC | 1 |
| Youn, SW | 1 |
| Beer, K | 1 |
| Zoraster, RM | 1 |
| Rison, RA | 1 |
| Prottey, C | 1 |
| George, D | 1 |
| Leech, RW | 1 |
| Black, JG | 1 |
| Howes, D | 1 |
| Vickers, CF | 1 |
| Monheit, GD | 1 |
| Kim, SW | 1 |
| Moon, SE | 1 |
| Kim, JA | 1 |
| Eun, HC | 1 |
| Al-Waiz, MM | 1 |
| Al-Sharqi, AI | 1 |
| Van Scott, EJ | 1 |
| Yu, RJ | 1 |
Clinical Trials (1)
Trial Overview
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| 6 Month Double-Blind Randomized Placebo-Controlled Trial to Evaluate the Safety and Efficacy of Small Particle Hyaluronic Acid to Treat Acne Scars Located on the Cheeks and Forehead[NCT02955381] | 26 participants (Actual) | Interventional | 2017-03-28 | Terminated (stopped due to Liquidation of Research Department) | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Reviews
3 reviews available for lactic acid and Acne
| Article | Year |
|---|---|
[Use of organic acids in acne and skin discolorations therapy].
Topics: Acne Vulgaris; Adolescent; Adult; Child; Dermatitis; Female; Glycolates; Gram-Positive Bacterial Inf | 2015 |
The Case for Synthetic Injectables.
Topics: Acne Vulgaris; Biocompatible Materials; Cosmetic Techniques; Dermal Fillers; Durapatite; Esthetics; | 2015 |
The Jessner's-trichloroacetic acid peel. An enhanced medium-depth chemical peel.
Topics: Acne Vulgaris; Chemexfoliation; Cicatrix; Drug Combinations; Ethanol; Face; Facial Dermatoses; Human | 1995 |
Trials
10 trials available for lactic acid and Acne
| Article | Year |
|---|---|
Intradermal Injection of Poly-d, l-Lactic Acid Using Microneedle Fractional Radiofrequency for Acne Scars: An Open-Label Prospective Trial.
Topics: Acne Vulgaris; Cicatrix; Humans; Injections, Intradermal; Lactic Acid; Prospective Studies | 2022 |
Intradermal Injection of Poly-d, l-Lactic Acid Using Microneedle Fractional Radiofrequency for Acne Scars: An Open-Label Prospective Trial.
Topics: Acne Vulgaris; Cicatrix; Humans; Injections, Intradermal; Lactic Acid; Prospective Studies | 2022 |
Intradermal Injection of Poly-d, l-Lactic Acid Using Microneedle Fractional Radiofrequency for Acne Scars: An Open-Label Prospective Trial.
Topics: Acne Vulgaris; Cicatrix; Humans; Injections, Intradermal; Lactic Acid; Prospective Studies | 2022 |
Intradermal Injection of Poly-d, l-Lactic Acid Using Microneedle Fractional Radiofrequency for Acne Scars: An Open-Label Prospective Trial.
Topics: Acne Vulgaris; Cicatrix; Humans; Injections, Intradermal; Lactic Acid; Prospective Studies | 2022 |
Microneedling (Dermapen) and Jessner's solution peeling in treatment of atrophic acne scars: a comparative randomized clinical study.
Topics: Acne Vulgaris; Chemexfoliation; Cicatrix; Combined Modality Therapy; Cosmetic Techniques; Drug Combi | 2019 |
Efficacy and safety of Jessner's solution peel in comparison with salicylic acid 30% peel in the management of patients with acne vulgaris and postacne hyperpigmentation with skin of color: a randomized, double-blinded, split-face, controlled trial.
Topics: Acne Vulgaris; Adult; Chemexfoliation; Double-Blind Method; Drug Combinations; Ethanol; Facial Derma | 2020 |
Comparative study of buffered 50% glycolic acid (pH 3.0) + 0.5% salicylic acid solution vs Jessner's solution in patients with acne vulgaris.
Topics: Acne Vulgaris; Adult; Chemexfoliation; Drug Combinations; Drug Therapy, Combination; Esthetics; Etha | 2018 |
Combination chemical peels are more effective than single chemical peel in treatment of mild-to-moderate acne vulgaris: A split face comparative clinical trial.
Topics: Acne Vulgaris; Adult; Analysis of Variance; Chemexfoliation; Drug Combinations; Drug Therapy, Combin | 2018 |
A randomized controlled study for the treatment of acne vulgaris using high-intensity 414 nm solid state diode arrays.
Topics: Acne Vulgaris; Adolescent; Adult; Combined Modality Therapy; Cosmetic Techniques; Double-Blind Metho | 2015 |
A Canadian study of the use of poly-L-lactic acid dermal implant for the treatment of hill and valley acne scarring.
Topics: Acne Vulgaris; Administration, Cutaneous; Adult; Biocompatible Materials; Canada; Cicatrix; Cosmetic | 2015 |
Jessner's solution vs. 30% salicylic acid peels: a comparative study of the efficacy and safety in mild-to-moderate acne vulgaris.
Topics: Acne Vulgaris; Adolescent; Chemexfoliation; Drug Combinations; Ethanol; Facial Dermatoses; Female; H | 2017 |
Salicylic acid peels versus Jessner's solution for acne vulgaris: a comparative study.
Topics: Acne Vulgaris; Adult; Chemexfoliation; Double-Blind Method; Drug Combinations; Ethanol; Face; Humans | 2013 |
Glycolic acid versus Jessner's solution: which is better for facial acne patients? A randomized prospective clinical trial of split-face model therapy.
Topics: Acne Vulgaris; Adolescent; Adult; Chemexfoliation; Drug Combinations; Ethanol; Facial Dermatoses; Fe | 1999 |
Other Studies
13 other studies available for lactic acid and Acne
| Article | Year |
|---|---|
Design of polymeric nanoparticles and its applications as drug delivery systems for acne treatment.
Topics: Acne Vulgaris; Cell Survival; Chemistry, Pharmaceutical; Delayed-Action Preparations; Dicarboxylic A | 2014 |
Novel retinoid ester in combination with salicylic acid for the treatment of acne.
Topics: Acne Vulgaris; Adult; Anti-Infective Agents; Detergents; Drug Combinations; Female; Humans; Keratoly | 2016 |
Injectable poly-L: -lactic acid: a novel sculpting agent for the treatment of dermal fat atrophy after severe acne.
Topics: Acne Vulgaris; Chronic Disease; Cicatrix; Esthetics; Female; Humans; Injections, Intradermal; Lactic | 2009 |
Case study involving use of injectable poly-L-lactic acid (PLLA) for acne scars.
Topics: Acne Vulgaris; Cellulose; Cicatrix; Female; Humans; Injections, Intradermal; Lactic Acid; Mannitol; | 2009 |
Lactic acid peeling in superficial acne scarring in Indian skin.
Topics: Acne Vulgaris; Adult; Cicatrix; Female; Humans; India; Keratolytic Agents; Lactic Acid; Pilot Projec | 2010 |
Commentary: salicylic acid peels versus Jessner's solution peels for acne vulgaris: a comparative study.
Topics: Acne Vulgaris; Chemexfoliation; Drug Combinations; Ethanol; Humans; Keratolytic Agents; Lactic Acid; | 2013 |
Dispelling the myth: appropriate use of poly-L-lactic acid and clinical considerations.
Topics: Acne Vulgaris; Biodegradation, Environmental; Cicatrix; Humans; Lactic Acid; Polyesters; Polymers; P | 2006 |
Effects of repetitive superficial chemical peels on facial sebum secretion in acne patients.
Topics: Acne Vulgaris; Adolescent; Adult; Chemexfoliation; Drug Combinations; Ethanol; Facial Dermatoses; Fe | 2006 |
A single-center, open-label study on the use of injectable poly-L-lactic acid for the treatment of moderate to severe scarring from acne or varicella.
Topics: Acne Vulgaris; Adult; Biocompatible Materials; Chickenpox; Cicatrix; Cosmetic Techniques; Face; Fema | 2007 |
Severe lactic acidosis secondary to minocycline in a teenager with infectious mononucleosis and mitochondrial myopathy.
Topics: Acidosis, Lactic; Acne Vulgaris; Adolescent; Anti-Bacterial Agents; DNA, Mitochondrial; Female; Huma | 2008 |
The mode of action of ethyl lactate as a treatment for acne.
Topics: Acne Vulgaris; Adolescent; Adult; Animals; Ethanol; Female; Humans; Hydrogen-Ion Concentration; Lact | 1984 |
Medium-depth chemical peels in the treatment of acne scars in dark-skinned individuals.
Topics: Acne Vulgaris; Adolescent; Adult; Caustics; Chemexfoliation; Cicatrix; Drug Combinations; Drug Thera | 2002 |
Alpha hydroxy acids: procedures for use in clinical practice.
Topics: Acne Vulgaris; Administration, Topical; Glycolates; Humans; Ichthyosis; Keratosis; Lactates; Lactic | 1989 |