Page last updated: 2024-10-19

niacinamide and Acne

niacinamide has been researched along with Acne in 29 studies

nicotinamide : A pyridinecarboxamide that is pyridine in which the hydrogen at position 3 is replaced by a carboxamide group.

Research Excerpts

ExcerptRelevanceReference
"5-1 mg/kg/day for papulo-pustular or nodulo-cystic acne were randomized to additionally receive a cream composed of 8% omega-ceramides, hydrophilic sugars, 5% niacinamide applied twice daily (group A) or placebo cream (group B) applied 2 times per day."9.27Reducing the oral isotretinoin skin side effects: efficacy of 8% omega-ceramides, hydrophilic sugars, 5% niacinamide cream compound in acne patients. ( Bianchi, L; Cannizzaro, MV; Dattola, A; Del Duca, E; Garofalo, V, 2018)
"Nicotinamide and clindamycin gels are two popular topical medications for acne vulgaris."9.17Topical 4% nicotinamide vs. 1% clindamycin in moderate inflammatory acne vulgaris. ( Amirnia, M; Fouladi, RF; Karimi, ER; Khodaeiani, E; Saeidi, M, 2013)
"In our double-blind investigation, the safety and efficacy of topically applied 4% nicotinamide gel was compared to 1% clindamycin gel for the treatment of moderate inflammatory acne vulgaris."9.08Topical nicotinamide compared with clindamycin gel in the treatment of inflammatory acne vulgaris. ( Chalker, DK; Parish, LC; Shalita, AR; Smith, JG; Sofman, MS, 1995)
"To assess the effects of topical treatments (azelaic acid, salicylic acid, nicotinamide, zinc, alpha-hydroxy acid, and sulphur) for acne."9.05Topical azelaic acid, salicylic acid, nicotinamide, sulphur, zinc and fruit acid (alpha-hydroxy acid) for acne. ( Liu, GJ; Liu, H; Liu, L; Peinemann, F; Sang, H; Xia, J; Yu, H, 2020)
"The effects of topical azelaic acid, salicylic acid, nicotinamide, sulfur, zinc, and fruit acid (alpha-hydroxy acid) for acne are unclear."9.05Evidence-based topical treatments (azelaic acid, salicylic acid, nicotinamide, sulfur, zinc, and fruit acid) for acne: an abridged version of a Cochrane systematic review. ( Liu, G; Liu, H; Liu, L; Peinemann, F; Sang, H; Xia, J; Yu, H, 2020)
"A multicenter prospective observational study was carried out on patients with a diagnosis of mild comedonal-papular facial acne to provide new evidence on the clinical effectiveness, tolerability and acceptability of three salicylic acid-based products for the topical treatment of acne in the daily clinical practice."7.96Effectiveness of a combination of salicylic acid-based products for the treatment of mild comedonal-papular acne: a multicenter prospective observational study. ( Bettoli, V; Micali, G; Monfrecola, G; Veraldi, S, 2020)
"Acne vulgaris is a chronic inflammatory skin disease that mostly develops during adolescence and continues throughout adulthood."6.94A retrospective assessment and comparison of the effectiveness of benzoyl peroxide; the combination of topical niacinamide, gallic acid, and lauric acid; and the combination of benzoyl peroxide and erythromycin in acne vulgaris. ( Akyol, M; Guner, RY; Kozan, A, 2020)
"Acne vulgaris is a common and chronic skin disease that impacts on physical and psychological perceptions."5.56Efficacy and safety of a new topical gel formulation containing retinol encapsulated in glycospheres and hydroxypinacolone retinoate, an antimicrobial peptide, salicylic acid, glycolic acid and niacinamide for the treatment of mild acne: preliminary resul ( Annunziata, MC; Cinelli, E; Donnarumma, M; Fabbrocini, G; Milani, M; Villani, A, 2020)
"5-1 mg/kg/day for papulo-pustular or nodulo-cystic acne were randomized to additionally receive a cream composed of 8% omega-ceramides, hydrophilic sugars, 5% niacinamide applied twice daily (group A) or placebo cream (group B) applied 2 times per day."5.27Reducing the oral isotretinoin skin side effects: efficacy of 8% omega-ceramides, hydrophilic sugars, 5% niacinamide cream compound in acne patients. ( Bianchi, L; Cannizzaro, MV; Dattola, A; Del Duca, E; Garofalo, V, 2018)
"Nicotinamide and clindamycin gels are two popular topical medications for acne vulgaris."5.17Topical 4% nicotinamide vs. 1% clindamycin in moderate inflammatory acne vulgaris. ( Amirnia, M; Fouladi, RF; Karimi, ER; Khodaeiani, E; Saeidi, M, 2013)
"0001) number of patients demonstrated improvement over their previous acne treatment regimens after both 4 and 8 weeks of NicAzel (nicotinamide, azelaic acid, zinc, pyridoxine, copper, folic acid; Elorac Inc, Vernon Hills, IL) use."5.16Inflammatory acne management with a novel prescription dietary supplement. ( Akhavan, A; Day, D; Falcon, R; Iannotta, P; Janiga, A; Kallal, JE; Olansky, A; Shalita, AR; Singri, P, 2012)
"This study evaluated the efficacy and tolerability of treating mild-to-moderate facial acne using a new, hand-held, light-emitting diode blue light device in conjunction with a foam cleanser containing 5% glycolic acid and 2% salicylic acid plus a skin rebuilding serum containing 1."5.15Evaluation of self-treatment of mild-to-moderate facial acne with a blue light treatment system. ( Dhawan, S; Wheeland, RG, 2011)
"In our double-blind investigation, the safety and efficacy of topically applied 4% nicotinamide gel was compared to 1% clindamycin gel for the treatment of moderate inflammatory acne vulgaris."5.08Topical nicotinamide compared with clindamycin gel in the treatment of inflammatory acne vulgaris. ( Chalker, DK; Parish, LC; Shalita, AR; Smith, JG; Sofman, MS, 1995)
"To assess the effects of topical treatments (azelaic acid, salicylic acid, nicotinamide, zinc, alpha-hydroxy acid, and sulphur) for acne."5.05Topical azelaic acid, salicylic acid, nicotinamide, sulphur, zinc and fruit acid (alpha-hydroxy acid) for acne. ( Liu, GJ; Liu, H; Liu, L; Peinemann, F; Sang, H; Xia, J; Yu, H, 2020)
"The effects of topical azelaic acid, salicylic acid, nicotinamide, sulfur, zinc, and fruit acid (alpha-hydroxy acid) for acne are unclear."5.05Evidence-based topical treatments (azelaic acid, salicylic acid, nicotinamide, sulfur, zinc, and fruit acid) for acne: an abridged version of a Cochrane systematic review. ( Liu, G; Liu, H; Liu, L; Peinemann, F; Sang, H; Xia, J; Yu, H, 2020)
"Nicotinamide (niacinamide), a physiologically active form of niacin (nicotinic acid), in combination with zinc is being assessed in clinical studies for the treatment of inflammatory skin diseases such as acne vulgaris and bullous pemphigoid."4.83The mechanisms of action of nicotinamide and zinc in inflammatory skin disease. ( Fivenson, DP, 2006)
"A multicenter prospective observational study was carried out on patients with a diagnosis of mild comedonal-papular facial acne to provide new evidence on the clinical effectiveness, tolerability and acceptability of three salicylic acid-based products for the topical treatment of acne in the daily clinical practice."3.96Effectiveness of a combination of salicylic acid-based products for the treatment of mild comedonal-papular acne: a multicenter prospective observational study. ( Bettoli, V; Micali, G; Monfrecola, G; Veraldi, S, 2020)
"Niacinamide has been verified in treating almost every skin disorder, viz."2.72Cosmeceutical Aptitudes of Niacinamide: A Review. ( Madaan, P; Malik, DS; Sikka, P, 2021)
"Acne and rosacea are common inflammatory processes historically classified in the same disease category, but evolving understanding of their disparate pathophysiology and exacerbating factors have generated an enormous armamentarium of therapeutic possibilities."2.53Over-the-counter treatments for acne and rosacea. ( Rosamilia, LL, 2016)
"The use of topical nicotinamide in the treatment of acne vulgaris; melasma; atopic dermatitis; rosacea; and oral nicotinamide in preventing nonmelanoma skin cancer is discussed."2.50A review of nicotinamide: treatment of skin diseases and potential side effects. ( Rolfe, HM, 2014)
" However, long-term use of these agents has drawbacks: steroids may induce numerous serious side effects such as hypertension, immunosuppression, and osteoporosis, and overuse of oral antibiotics may contribute to the development of bacterial resistance, as well as to a host of nuisance side effects such as diarrhea, yeast infections, and photosensitivity."2.43Pharmacologic doses of nicotinamide in the treatment of inflammatory skin conditions: a review. ( Niren, NM, 2006)
"Acne vulgaris is a common and chronic skin disease that impacts on physical and psychological perceptions."1.56Efficacy and safety of a new topical gel formulation containing retinol encapsulated in glycospheres and hydroxypinacolone retinoate, an antimicrobial peptide, salicylic acid, glycolic acid and niacinamide for the treatment of mild acne: preliminary resul ( Annunziata, MC; Cinelli, E; Donnarumma, M; Fabbrocini, G; Milani, M; Villani, A, 2020)

Research

Studies (29)

TimeframeStudies, this research(%)All Research%
pre-19901 (3.45)18.7374
1990's1 (3.45)18.2507
2000's3 (10.34)29.6817
2010's15 (51.72)24.3611
2020's9 (31.03)2.80

Authors

AuthorsStudies
Madaan, P1
Sikka, P1
Malik, DS1
Li, W1
Yu, Q1
Shen, Z1
Zhang, L1
Zhang, W1
Li, C1
Santos-Caetano, JP1
Gfeller, CF1
Mahalingam, H1
Thompson, M1
Moore, DJ1
Vila, R1
Doi, R1
Cargill, MR1
Abd-Allah, H1
Abdel-Aziz, RTA2
Nasr, M2
Liu, H2
Yu, H2
Xia, J2
Liu, L2
Liu, GJ1
Sang, H2
Peinemann, F2
Kozan, A1
Guner, RY1
Akyol, M1
Villani, A1
Annunziata, MC1
Cinelli, E1
Donnarumma, M1
Milani, M1
Fabbrocini, G1
Liu, G1
Bettoli, V2
Micali, G1
Monfrecola, G1
Veraldi, S2
Ibrahim, F1
El-Deen, AK1
El Abass, SA1
Shimizu, K1
Cannizzaro, MV1
Dattola, A1
Garofalo, V1
Del Duca, E1
Bianchi, L1
Karandikar, H1
Moftah, N1
Paradkar, A1
Khodaeiani, E1
Fouladi, RF1
Amirnia, M1
Saeidi, M1
Karimi, ER1
Chen, AC1
Damian, DL1
Rolfe, HM1
Rosamilia, LL1
Forbat, E1
Al-Niaimi, F1
Ali, FR1
Barros, BS1
Zaenglein, AL1
Walocko, FM1
Eber, AE1
Keri, JE1
Al-Harbi, MA1
Nouri, K1
Saint-Jean, M1
Khammari, A1
Seite, S1
Moyal, D1
Dreno, B1
Wheeland, RG1
Dhawan, S1
Morganti, P1
Berardesca, E1
Guarneri, B1
Guarneri, F1
Fabrizi, G1
Palombo, P1
Palombo, M1
Giovene, GL1
Guerriero, C1
Shalita, AR2
Falcon, R1
Olansky, A1
Iannotta, P1
Akhavan, A1
Day, D1
Janiga, A1
Singri, P1
Kallal, JE1
Niren, NM2
Fivenson, DP1
Torok, HM1
Smith, JG1
Parish, LC1
Sofman, MS1
Chalker, DK1
Jablonska, S1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Randomized, Parallel-group, Evaluator-blind, No-treatment and Positive Controlled, Single-site, Proof of Concept Clinical Study to Evaluate the Cosmetic Benefit Provided by 8 Weeks of Twice-daily Topical Application of a Developmental Moisturizing Cream[NCT03093181]157 participants (Actual)Interventional2017-04-04Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Change From Baseline in Corneometer Values at 8 Hours on Day 1

A blinded, trained and qualified evaluator conducted instrumental measurements of skin moisturization.Measurement of skin moisturization was performed by the electrical capacitance method with a Corneometer CM 865. The measuring principle was based on changes in the capacitance of the measuring head, functioning as a condensator. Between the conductors of the probe an electrical field was built which allows the dielectricity of the stratum corneum to be measured. Because the dielectricity of the skin varies as a function of its water content.The range of hydration level was 0 (as dry as possible)~120 AU (Arbitrary Unit)(most moist possible).Higher Corneometer values are indicative of improved skin moisturization. (NCT03093181)
Timeframe: At Baseline and Day 1

InterventionArbitrary Corneometer unit (Mean)
Test Product Regimen6.14
No Treatment Regimen2.63
Positive Control Regimen3.60

ANOVA Analysis on Improvement Rating of Lay Person Assessment of Polarized and Non-polarized Images Week 8 Compared to Baseline

Baseline and Week 8 photographs of all participants were displayed side by side on high resolution, color-calibrated display screen in room with neutral wall colors and standardized lighting with minimized glare. Relative positioning (left and right) of baseline and Week 8 photographs were blinded to evaluator and randomized. Lay evaluators ranked magnitude of improvement in overall appearance of blemishes using below criteria: Left=blemishes on left are more obvious than those on right; Right=blemishes on right are more obvious than those on left. Lay evaluator ranking for each image pair was converted into a numerical score based on whether Baseline or Week 8 image was ranked better:0=Baseline image was better than Week 8 image,1=Week 8 image was better than Baseline image. Minimum score 0 corresponded to all baseline images being better than Week 8 images. Maximum score 1 corresponded to all Week 8 images being better than baseline images. Higher scores indicated better results. (NCT03093181)
Timeframe: At Baseline and Week 8

,,
InterventionScore on scale (Least Squares Mean)
For Polarised ImageFor Non-polarised Image
No Treatment Regimen0.500.52
Positive Control Regimen0.510.51
Test Product Regimen0.650.67

Change From Baseline in Corneometer Values at 1 and 3 Hours on Day 1 and at Week 1, 4 and 8

A blinded, trained and qualified evaluator conducted instrumental measurements of skin moisturisation. Measurement of skin moisturisation was performed by the electrical capacitance method with a Corneometer CM 865. The measuring principle was based on changes in the capacitance of the measuring head, functioning as a condensator. Between the conductors of the probe an electrical field was built which allows the dielectricity of the stratum corneum to be measured. Because the dielectricity of the skin varies as a function of its water content. Higher Corneometer values are indicative of improved skin moisturisation. (NCT03093181)
Timeframe: At Baseline, Day 1, Week 1, 4 and 8

,,
InterventionArbitrary Corneometer unit (Mean)
At 1 hour, Day 1At 3 hour, Day 1At Week 1At Week 4At Week 8
No Treatment Regimen-3.690.680.063.163.32
Positive Control Regimen4.554.333.311.042.51
Test Product Regimen11.529.644.394.337.54

Change From Baseline in Evaluator's Assessment of Total Blemish Count at Week 1, 4, and 8

A treatment blind, trained and qualified evaluator counted the total number of facial blemishes on the forehead, cheeks and chin of the participants. (NCT03093181)
Timeframe: At Baseline, Week 1, 4 and 8

,,
InterventionTotal Blemish Count (Mean)
At Week 1At Week 4At Week 8
No Treatment Regimen-1.05-2.76-3.79
Positive Control Regimen-0.93-4.00-5.12
Test Product Regimen-0.70-3.86-5.68

Change From Baseline in Sebum Excretion Rate at Week 1, 4 and 8

The forehead of each participant was thoroughly cleansed by the investigator or designee using cotton pads saturated with 70% Isopropyl Alcohol and, after 5 minutes, the central area of the forehead above the eyebrows was measured in triplicate with a Sebumeter. The same area was measured in triplicate 90 minutes after cleansing. The sebum excretion rate was calculated by the difference in 90th minutes and 5th minute Sebumeter values. (NCT03093181)
Timeframe: At Baseline, Week 1, 4 and 8

,,
Interventionμg/cm^2 (Mean)
At Week 1At Week 4At Week 8
No Treatment Regimen38.7244.9732.91
Positive Control Regimen66.7353.1767.10
Test Product Regimen20.3630.4938.04

Change From Baseline in Sebumeter Values at Week 1, 4 and 8

A treatment blinded, trained and qualified evaluator conducted instrumental measurements of skin sebum levels. Measurement of skin sebum levels was performed by with a Sebumeter SM 815. The measurement principle of the SM 815 is based on grease spot photometry. The translucent tape of the device is brought into contact with skin and becomes increasingly transparent in response to surface oil. The tape is inserted into the aperture of the device and its transparency measured by light transmission, with increased transmission signifying increased oiliness. The software outputs mass sebum levels as a function of area. Sebumeter measurements were taken in triplicate at the central forehead (above the eyebrows) with the participant lying horizontally, on their back. (NCT03093181)
Timeframe: At Baseline, Week 1, 4 and 8

,,
InterventionMicrograms (μg)/square centimeter (cm^2) (Mean)
At Week 1At Week 4At Week 8
No Treatment Regimen-70.50-67.52-87.04
Positive Control Regimen-52.19-21.67-65.85
Test Product Regimen-54.98-49.57-86.49

Odds for Logistic Regression Analysis on Improvement Rating of Lay Person Assessment of Polarized and Non-polarized Images Week 8 Compared to Baseline

The baseline and week 8 photographs of all participants were displayed side by side on high resolution, color-calibrated display screen in room with neutral wall colors and standardized lighting and all practical efforts were made to minimize glare. The relative positioning (left and right) of baseline and week 8 photographs were blinded to evaluator and randomized. A technician used randomization schedule to display pair of images to lay evaluator. Lay evaluators judged magnitude of improvement in overall appearance of blemishes using the below criteria: Left=blemishes on left are more obvious than those on the right and Right=blemishes on right are more obvious than those on the left. Layperson ranked both left and right image as follows:1=Better;2=Worse. Odds was calculated from logistic regression including treatment and age stratum effects and exchangeable correlation. Odds=p/(1-p) where p was the probability of event that Week 8 was better than baseline. (NCT03093181)
Timeframe: At Baseline and Week 8

,,
InterventionOdds (Number)
For Polarised ImageFor Non-polarised Image
No Treatment Regimen1.001.08
Positive Control Regimen1.041.02
Test Product Regimen1.842.06

Reviews

11 reviews available for niacinamide and Acne

ArticleYear
Cosmeceutical Aptitudes of Niacinamide: A Review.
    Recent advances in anti-infective drug discovery, 2021, Volume: 16, Issue:3

    Topics: Acne Vulgaris; Aptitude; Cosmeceuticals; Humans; Niacinamide; Skin Diseases

2021
Topical azelaic acid, salicylic acid, nicotinamide, sulphur, zinc and fruit acid (alpha-hydroxy acid) for acne.
    The Cochrane database of systematic reviews, 2020, 05-01, Volume: 5

    Topics: Acne Vulgaris; Adapalene; Adolescent; Adult; Anti-Bacterial Agents; Benzoyl Peroxide; Bias; Child; C

2020
Evidence-based topical treatments (azelaic acid, salicylic acid, nicotinamide, sulfur, zinc, and fruit acid) for acne: an abridged version of a Cochrane systematic review.
    Journal of evidence-based medicine, 2020, Volume: 13, Issue:4

    Topics: Acne Vulgaris; Administration, Cutaneous; Dermatologic Agents; Dicarboxylic Acids; Fruit; Glycolates

2020
Nicotinamide and the skin.
    The Australasian journal of dermatology, 2014, Volume: 55, Issue:3

    Topics: Acne Vulgaris; Animals; Autoimmune Diseases; Carcinogenesis; Dermatitis, Atopic; Humans; Keratosis,

2014
A review of nicotinamide: treatment of skin diseases and potential side effects.
    Journal of cosmetic dermatology, 2014, Volume: 13, Issue:4

    Topics: Acne Vulgaris; Administration, Cutaneous; Administration, Oral; Chemical and Drug Induced Liver Inju

2014
Over-the-counter treatments for acne and rosacea.
    Seminars in cutaneous medicine and surgery, 2016, Volume: 35, Issue:2

    Topics: Acne Vulgaris; Administration, Cutaneous; Astringents; Benzoyl Peroxide; Dermatologic Agents; Deterg

2016
Use of nicotinamide in dermatology.
    Clinical and experimental dermatology, 2017, Volume: 42, Issue:2

    Topics: Acne Vulgaris; Dermatitis, Atopic; Humans; Niacinamide; Pigmentation Disorders; Pruritus; Skin Disea

2017
The Use of Cosmeceuticals in Acne: Help or Hoax?
    American journal of clinical dermatology, 2017, Volume: 18, Issue:2

    Topics: Acne Vulgaris; Complementary Therapies; Contraindications; Cosmeceuticals; Deception; Glycolates; Hu

2017
The role of nicotinamide in acne treatment.
    Dermatologic therapy, 2017, Volume: 30, Issue:5

    Topics: Acne Vulgaris; Administration, Cutaneous; Administration, Oral; Anti-Bacterial Agents; Anti-Inflamma

2017
Pharmacologic doses of nicotinamide in the treatment of inflammatory skin conditions: a review.
    Cutis, 2006, Volume: 77, Issue:1 Suppl

    Topics: Acne Vulgaris; Anti-Inflammatory Agents; Drug Combinations; Humans; Immunoglobulin A; Niacinamide; R

2006
The mechanisms of action of nicotinamide and zinc in inflammatory skin disease.
    Cutis, 2006, Volume: 77, Issue:1 Suppl

    Topics: Acne Vulgaris; Anti-Inflammatory Agents; Drug Combinations; Humans; Lipogenesis; Molecular Structure

2006

Trials

13 trials available for niacinamide and Acne

ArticleYear
Efficacy and safety of a cream containing octyl salicylic acid, salicylic acid, linoleic acid, nicotinamide, and piroctone olamine combined with 5% benzoyl peroxide in the treatment of acne vulgaris: a randomized controlled study.
    Chinese medical journal, 2022, 06-05, Volume: 135, Issue:11

    Topics: Acne Vulgaris; Benzoyl Peroxide; Drug Combinations; Ethanolamines; Gels; Humans; Linoleic Acid; Niac

2022
Cosmetic benefits of a novel biomimetic lamellar formulation containing niacinamide in healthy females with oily, blemish-prone skin in a randomized proof-of-concept study.
    International journal of cosmetic science, 2020, Volume: 42, Issue:1

    Topics: Acne Vulgaris; Adolescent; Adult; Biomimetics; Cosmetics; Female; Humans; Middle Aged; Niacinamide;

2020
A retrospective assessment and comparison of the effectiveness of benzoyl peroxide; the combination of topical niacinamide, gallic acid, and lauric acid; and the combination of benzoyl peroxide and erythromycin in acne vulgaris.
    Dermatologic therapy, 2020, Volume: 33, Issue:4

    Topics: Acne Vulgaris; Adolescent; Adult; Anti-Bacterial Agents; Benzoyl Peroxide; Dermatologic Agents; Eryt

2020
Reducing the oral isotretinoin skin side effects: efficacy of 8% omega-ceramides, hydrophilic sugars, 5% niacinamide cream compound in acne patients.
    Giornale italiano di dermatologia e venereologia : organo ufficiale, Societa italiana di dermatologia e sifilografia, 2018, Volume: 153, Issue:2

    Topics: Acne Vulgaris; Administration, Cutaneous; Administration, Oral; Adolescent; Adult; Ceramides; Dermat

2018
Novel nicotinamide skin-adhesive hot melt extrudates for treatment of acne.
    Expert opinion on drug delivery, 2018, Volume: 15, Issue:12

    Topics: Acne Vulgaris; Adhesives; Adolescent; Adult; Animals; Drug Compounding; Female; Hot Temperature; Hum

2018
Topical 4% nicotinamide vs. 1% clindamycin in moderate inflammatory acne vulgaris.
    International journal of dermatology, 2013, Volume: 52, Issue:8

    Topics: Acne Vulgaris; Administration, Topical; Adolescent; Adult; Anti-Bacterial Agents; Clindamycin; Doubl

2013
Characteristics of premenstrual acne flare-up and benefits of a dermocosmetic treatment: a double-blind randomised trial.
    European journal of dermatology : EJD, 2017, Apr-01, Volume: 27, Issue:2

    Topics: Acne Vulgaris; Adolescent; Adult; Cosmeceuticals; Double-Blind Method; Drug Combinations; Ethanolami

2017
Evaluation of self-treatment of mild-to-moderate facial acne with a blue light treatment system.
    Journal of drugs in dermatology : JDD, 2011, Volume: 10, Issue:6

    Topics: Acne Vulgaris; Adult; Combined Modality Therapy; Dermatologic Agents; Dicarboxylic Acids; Drug Combi

2011
Topical clindamycin 1% vs. linoleic acid-rich phosphatidylcholine and nicotinamide 4% in the treatment of acne: a multicentre-randomized trial.
    International journal of cosmetic science, 2011, Volume: 33, Issue:5

    Topics: Acne Vulgaris; Administration, Topical; Anti-Bacterial Agents; Clindamycin; Double-Blind Method; Hum

2011
Efficacy and tolerability of topical 0.2% Myrtacine® and 4% vitamin PP for prevention and treatment of retinoid dermatitis in patients with mild to moderate acne.
    Giornale italiano di dermatologia e venereologia : organo ufficiale, Societa italiana di dermatologia e sifilografia, 2012, Volume: 147, Issue:5

    Topics: Acne Vulgaris; Administration, Topical; Adolescent; Adult; Anti-Inflammatory Agents; Child; Drug Com

2012
Inflammatory acne management with a novel prescription dietary supplement.
    Journal of drugs in dermatology : JDD, 2012, Volume: 11, Issue:12

    Topics: Acne Vulgaris; Adolescent; Adult; Anti-Bacterial Agents; Child; Copper; Dicarboxylic Acids; Dietary

2012
The Nicomide Improvement in Clinical Outcomes Study (NICOS): results of an 8-week trial.
    Cutis, 2006, Volume: 77, Issue:1 Suppl

    Topics: Acne Vulgaris; Adolescent; Adult; Anti-Inflammatory Agents; Child; Dose-Response Relationship, Drug;

2006
Topical nicotinamide compared with clindamycin gel in the treatment of inflammatory acne vulgaris.
    International journal of dermatology, 1995, Volume: 34, Issue:6

    Topics: Acne Vulgaris; Administration, Topical; Adolescent; Adult; Clindamycin; Dermatitis; Double-Blind Met

1995

Other Studies

5 other studies available for niacinamide and Acne

ArticleYear
Chitosan nanoparticles making their way to clinical practice: A feasibility study on their topical use for acne treatment.
    International journal of biological macromolecules, 2020, Aug-01, Volume: 156

    Topics: Acne Vulgaris; Administration, Topical; Adolescent; Adult; Chitosan; Drug Carriers; Drug Stability;

2020
Efficacy and safety of a new topical gel formulation containing retinol encapsulated in glycospheres and hydroxypinacolone retinoate, an antimicrobial peptide, salicylic acid, glycolic acid and niacinamide for the treatment of mild acne: preliminary resul
    Giornale italiano di dermatologia e venereologia : organo ufficiale, Societa italiana di dermatologia e sifilografia, 2020, Volume: 155, Issue:5

    Topics: Acne Vulgaris; Administration, Topical; Adolescent; Adult; Anti-Infective Agents; Female; Gels; Glyc

2020
Effectiveness of a combination of salicylic acid-based products for the treatment of mild comedonal-papular acne: a multicenter prospective observational study.
    Giornale italiano di dermatologia e venereologia : organo ufficiale, Societa italiana di dermatologia e sifilografia, 2020, Volume: 155, Issue:6

    Topics: Acne Vulgaris; Adult; Carbamide Peroxide; Dermatologic Agents; Drug Combinations; Facial Dermatoses;

2020
An ecofriendly green liquid chromatographic method for simultaneous determination of nicotinamide and clindamycin phosphate in pharmaceutical gel for acne treatment.
    Journal of food and drug analysis, 2017, Volume: 25, Issue:3

    Topics: Acne Vulgaris; Chemistry, Pharmaceutical; Chromatography, Liquid; Clindamycin; Drug Stability; Hydro

2017
Letter: Treatment of acne vulgaris and rosacea.
    Archives of dermatology, 1975, Volume: 111, Issue:7

    Topics: Acne Vulgaris; Administration, Topical; Ascorbic Acid; Humans; Niacinamide; Pyridoxine; Riboflavin;

1975