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trimethoprim and Acne

trimethoprim has been researched along with Acne in 23 studies

Trimethoprim: A pyrimidine inhibitor of dihydrofolate reductase, it is an antibacterial related to PYRIMETHAMINE. It is potentiated by SULFONAMIDES and the TRIMETHOPRIM, SULFAMETHOXAZOLE DRUG COMBINATION is the form most often used. It is sometimes used alone as an antimalarial. TRIMETHOPRIM RESISTANCE has been reported.
trimethoprim : An aminopyrimidine antibiotic whose structure consists of pyrimidine 2,4-diamine and 1,2,3-trimethoxybenzene moieties linked by a methylene bridge.

Research Excerpts

ExcerptRelevanceReference
"42 patients with acne vulgaris, clinically resistant to prior therapy with tetracyclines, were evaluated after therapy with sulphamethoxazole-trimethoprim (400 + 80 mg) twice daily."9.04A clinical and bacteriological evaluation of the effect of sulphamethoxazole-trimethoprim in acne vulgaris, resistant to prior therapy with tetracyclines. ( Fredriksson, T; Hallander, H; Nordin, K; Rylander, C, 1978)
"Drug-induced aseptic meningitis attributable to trimethoprim alone has only rarely been documented in the literature."7.71Trimethoprim-induced aseptic meningitis in an adolescent male. ( DeMaio, J; Hood, M; Miller, JB; Redman, RC, 2002)
" All patients received trimethoprim in a dosage of 300 mg twice daily for at least 4 months, unless it had been withdrawn due to side effects."5.29Oral trimethoprim as a third-line antibiotic in the management of acne vulgaris. ( Bottomley, WW; Cunliffe, WJ, 1993)
"42 patients with acne vulgaris, clinically resistant to prior therapy with tetracyclines, were evaluated after therapy with sulphamethoxazole-trimethoprim (400 + 80 mg) twice daily."5.04A clinical and bacteriological evaluation of the effect of sulphamethoxazole-trimethoprim in acne vulgaris, resistant to prior therapy with tetracyclines. ( Fredriksson, T; Hallander, H; Nordin, K; Rylander, C, 1978)
"Drug-induced aseptic meningitis attributable to trimethoprim alone has only rarely been documented in the literature."3.71Trimethoprim-induced aseptic meningitis in an adolescent male. ( DeMaio, J; Hood, M; Miller, JB; Redman, RC, 2002)
"Strains of propionibacteria resistant to clindamycin or clindamycin and erythromycin were isolated from four patients with acne, three of whom were receiving clindamycin."3.66Resistance of propionibacteria to antibiotics used in the treatment of acne. ( Brown, JM; Poston, SM, 1983)
" The widespread and long-term use of antibiotics over the years has unfortunately led to the emergence of resistant bacteria."2.43Acne vulgaris: a review of antibiotic therapy. ( Tan, AW; Tan, HH, 2005)
" Doubling of erythromycine dosage could not prevent premenstrual exacerbation of acne."1.27On therapeutic approaches to some special types of acne. ( Rajka, G, 1985)

Research

Studies (23)

TimeframeStudies, this research(%)All Research%
pre-199018 (78.26)18.7374
1990's2 (8.70)18.2507
2000's2 (8.70)29.6817
2010's1 (4.35)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Boyd, A1
Mills, D1
Hook, K1
Kaila, R1
Redman, RC1
Miller, JB1
Hood, M1
DeMaio, J1
Tan, AW1
Tan, HH1
Gibson, JR1
Darley, CR1
Harvey, SG1
Barth, J1
Eady, EA1
Holland, KT1
Cunliffe, WJ3
Brown, JM1
Poston, SM1
Jen, I1
Harcup, JW1
Cooper, J1
Holm, SE1
Burman, LG1
Rich, M1
Bottomley, WW1
Aldana, OL1
Goulden, V1
Hellgren, L1
Vincent, J1
Nordin, K1
Hallander, H1
Fredriksson, T1
Rylander, C1
Stankler, L1
Piamphongsant, T1
Rajka, G1
Heynen, U1
Macdonald, RH1
Macconnell, LE1
Dunsmore, IR1
Mahal, H1
Hersle, K1
Lange, D1
Schirren, C1

Reviews

4 reviews available for trimethoprim and Acne

ArticleYear
Acne vulgaris: a review of antibiotic therapy.
    Expert opinion on pharmacotherapy, 2005, Volume: 6, Issue:3

    Topics: Acne Vulgaris; Administration, Topical; Anti-Bacterial Agents; Erythromycin; Humans; Tetracyclines;

2005
The use of antibiotics in acne therapy: oral or topical administration?
    The Journal of antimicrobial chemotherapy, 1982, Volume: 10, Issue:2

    Topics: Acne Vulgaris; Administration, Oral; Administration, Topical; Anti-Bacterial Agents; Chloramphenicol

1982
Ad Hoc Committee report: systemic antibiotics for treatment of acne vulgaris: efficacy and safety.
    Archives of dermatology, 1975, Volume: 111, Issue:12

    Topics: Acne Vulgaris; Adolescent; Adult; Anti-Bacterial Agents; Child; Clindamycin; Clinical Trials as Topi

1975
[Eusaprim-equivalent to broad spectrum antibiotics].
    Zeitschrift fur Allgemeinmedizin, 1971, Oct-31, Volume: 47, Issue:30

    Topics: Acne Vulgaris; Animals; Anti-Bacterial Agents; Bacteria; Bacterial Infections; Bronchitis; Child; Ch

1971

Trials

7 trials available for trimethoprim and Acne

ArticleYear
Oral trimethoprim versus oxytetracycline in the treatment of inflammatory acne vulgaris.
    The British journal of dermatology, 1982, Volume: 107, Issue:2

    Topics: Acne Vulgaris; Adolescent; Adult; Female; Humans; Inflammation; Male; Oxytetracycline; Random Alloca

1982
A comparison of low dosage trimethoprim/sulfamethoxazole with oxytetracycline in acne vulgaris.
    Cutis, 1980, Volume: 26, Issue:1

    Topics: Acne Vulgaris; Double-Blind Method; Drug Combinations; Female; Humans; Male; Oxytetracycline; Sulfam

1980
The treatment of acne vulgaris in general practice. A double-blind assessment of co-trimoxazole and tetracycline.
    The Practitioner, 1980, Volume: 224, Issue:1345

    Topics: Acne Vulgaris; Adolescent; Clinical Trials as Topic; Double-Blind Method; Drug Combinations; Female;

1980
Ad Hoc Committee report: systemic antibiotics for treatment of acne vulgaris: efficacy and safety.
    Archives of dermatology, 1975, Volume: 111, Issue:12

    Topics: Acne Vulgaris; Adolescent; Adult; Anti-Bacterial Agents; Child; Clindamycin; Clinical Trials as Topi

1975
A clinical and bacteriological evaluation of the effect of sulphamethoxazole-trimethoprim in acne vulgaris, resistant to prior therapy with tetracyclines.
    Dermatologica, 1978, Volume: 157, Issue:4

    Topics: Acne Vulgaris; Adolescent; Adult; Child; Clinical Trials as Topic; Drug Combinations; Drug Evaluatio

1978
Trimethoprim-sulphamethoxazole versus placebo in acne vulgaris.
    The British journal of clinical practice, 1972, Volume: 26, Issue:2

    Topics: Acne Vulgaris; Adolescent; Adult; Anti-Infective Agents; Child; Clinical Trials as Topic; Folic Acid

1972
Trimethoprim-sulphamethoxazole in acne vulgaris. A double-blind study.
    Dermatologica, 1972, Volume: 145, Issue:3

    Topics: Acne Vulgaris; Adolescent; Adult; Anti-Infective Agents; Clinical Trials as Topic; Female; Folic Aci

1972

Other Studies

13 other studies available for trimethoprim and Acne

ArticleYear
Seventeen-year-old sexually active male with rash.
    The American journal of emergency medicine, 2016, Volume: 34, Issue:4

    Topics: Acne Vulgaris; Adolescent; Anti-Infective Agents; Drug Hypersensitivity Syndrome; Exanthema; Fever;

2016
Trimethoprim-induced aseptic meningitis in an adolescent male.
    Pediatrics, 2002, Volume: 110, Issue:2 Pt 1

    Topics: Acne Vulgaris; Adolescent; Anti-Infective Agents; Humans; Male; Meningitis, Aseptic; Trimethoprim

2002
Resistance of propionibacteria to antibiotics used in the treatment of acne.
    Journal of medical microbiology, 1983, Volume: 16, Issue:3

    Topics: Acne Vulgaris; Anti-Bacterial Agents; Clindamycin; Drug Resistance, Microbial; Erythromycin; Humans;

1983
General considerations by a clinical bacteriologist regarding antibiotic therapy in acne.
    Acta dermato-venereologica. Supplementum, 1980, Volume: Suppl 89

    Topics: Acne Vulgaris; Anti-Bacterial Agents; Clindamycin; Erythromycin; Humans; Propionibacterium acnes; R

1980
Acne: emphasis on adolescent acne and the role of antibiotics.
    Australian family physician, 1980, Volume: 9, Issue:11

    Topics: Acne Vulgaris; Adolescent; Adult; Anti-Bacterial Agents; Benzoyl Peroxide; Child; Clindamycin; Eryth

1980
Oral trimethoprim as a third-line antibiotic in the management of acne vulgaris.
    Dermatology (Basel, Switzerland), 1993, Volume: 187, Issue:3

    Topics: Acne Vulgaris; Administration, Oral; Adolescent; Adult; Female; Humans; Male; Middle Aged; Retrospec

1993
Oral trimethoprim: a relatively safe and successful third-line treatment for acne vulgaris.
    The British journal of dermatology, 1999, Volume: 141, Issue:4

    Topics: Acne Vulgaris; Administration, Oral; Adult; Anti-Bacterial Agents; Female; Humans; Male; Retrospecti

1999
Changes of skin surface lipids in acne vulgaris after treatment with trimethoprim-sulphamethoxazole.
    Dermatologische Monatschrift, 1976, Volume: 162, Issue:8

    Topics: Acne Vulgaris; Adolescent; Adult; Fatty Acids, Nonesterified; Female; Humans; Lipid Metabolism; Male

1976
Pustular acne vulgaris. Rotational oral antibacterial therapy for 1 year.
    The British journal of clinical practice, 1979, Volume: 33, Issue:5

    Topics: Acne Vulgaris; Adolescent; Adult; Clindamycin; Drug Administration Schedule; Drug Combinations; Fema

1979
Pustular acne.
    International journal of dermatology, 1985, Volume: 24, Issue:7

    Topics: Acne Vulgaris; Adult; Ampicillin; Clindamycin; Drug Combinations; Female; Humans; Male; Penicillin R

1985
On therapeutic approaches to some special types of acne.
    Acta dermato-venereologica. Supplementum, 1985, Volume: 120

    Topics: Acne Vulgaris; Administration, Topical; Adolescent; Adult; Androgen Antagonists; Anti-Inflammatory A

1985
[Treatment of non specific bacteriologic skin diseases using the bactericidally acting, broad spectrum chemotherapeutic preparation Bactrim Roche].
    Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete, 1972, Volume: 23, Issue:7

    Topics: Acne Vulgaris; Adult; Anti-Infective Agents; Child; Drug Combinations; Drug Resistance, Microbial; F

1972
[Studies on the influence of trimethoprim/sulfamethoxazole on the quality of sperm in andrologic patients and a contribution to the pharmacological testing of a drug on the spermatogenetic activity of the testis].
    Zeitschrift fur Hautkrankheiten, 1974, Oct-15, Volume: 49, Issue:20

    Topics: Acne Vulgaris; Eczema; Humans; Male; Prostatitis; Sperm Motility; Spermatogenesis; Spermatozoa; Sulf

1974