Page last updated: 2024-10-30

metformin and Acne

metformin has been researched along with Acne in 29 studies

Metformin: A biguanide hypoglycemic agent used in the treatment of non-insulin-dependent diabetes mellitus not responding to dietary modification. Metformin improves glycemic control by improving insulin sensitivity and decreasing intestinal absorption of glucose. (From Martindale, The Extra Pharmacopoeia, 30th ed, p289)
metformin : A member of the class of guanidines that is biguanide the carrying two methyl substituents at position 1.

Research Excerpts

ExcerptRelevanceReference
"This study compared the efficacy of metformin and doxycycline in treating patients with acne vulgaris."9.69Efficacy of metformin vs. doxycycline in treating acne vulgaris: An assessor-blinded, add-on, randomized, controlled clinical trial. ( Javaheri, R; Parvizi, MM; Sadati, MS; Shahriarirad, R; Yazdanpanah, N, 2023)
" Metformin, through inhibition of mTORC1 may improve acne."9.30Metformin as an adjunct therapy for the treatment of moderate to severe acne vulgaris: A randomized open-labeled study. ( Kwan, Z; Robinson, S; Tang, MM, 2019)
"There was heterogeneity across some studies due to different acne assessment scales, metformin dosages, and treatment durations."9.12Metformin Therapy for Acne in Patients with Polycystic Ovary Syndrome: A Systematic Review and Meta-analysis. ( Chang, YT; Huang, YC; Yee, FJ; Yen, H, 2021)
"The purpose of this literature review is to evaluate the use of metformin as an adjunct therapy in the treatment of moderate-to-severe acne in those not diagnosed with polycystic ovary syndrome (PCOS) or androgen excess."8.95Metformin as an adjunct therapy for the treatment of moderate to severe acne vulgaris. ( Lee, JK; Smith, AD, 2017)
"The object of this review was to compare metformin versus oral contraceptive pill (OCP) treatment in polycystic ovary syndrome."8.84Metformin versus oral contraceptive pill in polycystic ovary syndrome: a Cochrane review. ( Costello, MF; Eden, J; Johnson, NP; Shrestha, B; Sjoblom, P, 2007)
" Metformin is commonly used for treatment of acne in patients with polycystic ovarian syndrome (PCOS)."8.31Effects of metformin on clinical, hormonal and relevant gene expression parameters in patients with acne: an observational study. ( De, D; Dutta, P; Handa, S; Kamboj, P; Kaushik, A; Pal, A; Saikia, UN, 2023)
"To evaluate the role of metformin in the treatment of acne vulgaris by reducing the level of insulin-like growth factor 1."8.12The potential role of insulin-like growth factor 1 in acne vulgaris and its correlation with the clinical response before and after treatment with metformin. ( Abd-Elaal, WH; AbouHadeed, MH; Albalat, W; Darwish, H; Essam, R, 2022)
"Evidence for the effectiveness of metformin in the treatment of acne is limited."8.02Effects of metformin on experimentally induced acne on rabbit ear. ( Bishnoi, A; De, D; Dutta, P; Handa, S; Kamboj, P; Nahar Saikia, U; Pal, A, 2021)
"Treatment with metformin three times 500 mg daily had been advised since 2002, to patients suffering from the polycystic ovary syndrome diagnosed by the Rotterdam criteria and who did not want to take contraceptive pills."7.77[Metformin treatment with or without life style changes in patients with polycystic ovary syndrome]. ( Petrányi, G; Zaoura-Petrányi, M, 2011)
"Acne is a common and complex skin disease, with a very complex pathogenesis."6.82Low glycaemic diet and metformin therapy: a new approach in male subjects with acne resistant to common treatments. ( Colao, A; Del Prete, M; Donnarumma, M; Fabbrocini, G; Faggiano, A; Izzo, R; Marasca, C; Marciello, F; Monfrecola, G; Savastano, R, 2016)
"Metformin was then given at a dose of 500 mg three times a day for 8 weeks, after which time the pretreatment study was repeated."6.71Effects of metformin therapy on hyperandrogenism in women with polycystic ovarian syndrome. ( Dehghan-Kooshkghazi, M; Kazerooni, T, 2003)
"Hirsutism is a common and distressing symptom frequently encountered in women with polycystic ovary syndrome (PCOS), who also show relative insulin resistance."6.71Metformin or antiandrogen in the treatment of hirsutism in polycystic ovary syndrome. ( Fleming, R; Harborne, L; Lyall, H; Norman, J; Sattar, N, 2003)
"Metformin and OCPs were similar in terms of impact on hirsutism."6.53Metformin or Oral Contraceptives for Adolescents With Polycystic Ovarian Syndrome: A Meta-analysis. ( Al Khalifah, RA; Bassilious, E; Dennis, B; Florez, ID; Thabane, L, 2016)
" Metformin, through inhibition of mTORC1 may improve acne."5.30Metformin as an adjunct therapy for the treatment of moderate to severe acne vulgaris: A randomized open-labeled study. ( Kwan, Z; Robinson, S; Tang, MM, 2019)
"There was heterogeneity across some studies due to different acne assessment scales, metformin dosages, and treatment durations."5.12Metformin Therapy for Acne in Patients with Polycystic Ovary Syndrome: A Systematic Review and Meta-analysis. ( Chang, YT; Huang, YC; Yee, FJ; Yen, H, 2021)
"The purpose of this literature review is to evaluate the use of metformin as an adjunct therapy in the treatment of moderate-to-severe acne in those not diagnosed with polycystic ovary syndrome (PCOS) or androgen excess."4.95Metformin as an adjunct therapy for the treatment of moderate to severe acne vulgaris. ( Lee, JK; Smith, AD, 2017)
"The object of this review was to compare metformin versus oral contraceptive pill (OCP) treatment in polycystic ovary syndrome."4.84Metformin versus oral contraceptive pill in polycystic ovary syndrome: a Cochrane review. ( Costello, MF; Eden, J; Johnson, NP; Shrestha, B; Sjoblom, P, 2007)
" Metformin is commonly used for treatment of acne in patients with polycystic ovarian syndrome (PCOS)."4.31Effects of metformin on clinical, hormonal and relevant gene expression parameters in patients with acne: an observational study. ( De, D; Dutta, P; Handa, S; Kamboj, P; Kaushik, A; Pal, A; Saikia, UN, 2023)
"The aim of the study was to investigate immune-mediated (urticaria, allergic contact dermatitis, and psoriasis) and androgen-mediated (acanthosis nigricans, hidradenitis suppurativa, and acne) skin diseases associated with metformin use."4.31Differential Effects of Metformin on Immune-Mediated and Androgen-Mediated Non-Cancer Skin Diseases in Diabetes Patients: A Retrospective Cohort Study. ( Tseng, CH, 2023)
"Evidence for the effectiveness of metformin in the treatment of acne is limited."4.02Effects of metformin on experimentally induced acne on rabbit ear. ( Bishnoi, A; De, D; Dutta, P; Handa, S; Kamboj, P; Nahar Saikia, U; Pal, A, 2021)
"Treatment with metformin three times 500 mg daily had been advised since 2002, to patients suffering from the polycystic ovary syndrome diagnosed by the Rotterdam criteria and who did not want to take contraceptive pills."3.77[Metformin treatment with or without life style changes in patients with polycystic ovary syndrome]. ( Petrányi, G; Zaoura-Petrányi, M, 2011)
"Metformin is an established staple drug in the management of Type 2 diabetes mellitus."3.01A systematic review of the uses of metformin in dermatology. ( Al-Niaimi, F; Ali, FR; Raza, S, 2023)
"Acne is a common and complex skin disease, with a very complex pathogenesis."2.82Low glycaemic diet and metformin therapy: a new approach in male subjects with acne resistant to common treatments. ( Colao, A; Del Prete, M; Donnarumma, M; Fabbrocini, G; Faggiano, A; Izzo, R; Marasca, C; Marciello, F; Monfrecola, G; Savastano, R, 2016)
"Metformin was then given at a dose of 500 mg three times a day for 8 weeks, after which time the pretreatment study was repeated."2.71Effects of metformin therapy on hyperandrogenism in women with polycystic ovarian syndrome. ( Dehghan-Kooshkghazi, M; Kazerooni, T, 2003)
"Hirsutism is a common and distressing symptom frequently encountered in women with polycystic ovary syndrome (PCOS), who also show relative insulin resistance."2.71Metformin or antiandrogen in the treatment of hirsutism in polycystic ovary syndrome. ( Fleming, R; Harborne, L; Lyall, H; Norman, J; Sattar, N, 2003)
"Metformin and OCPs were similar in terms of impact on hirsutism."2.53Metformin or Oral Contraceptives for Adolescents With Polycystic Ovarian Syndrome: A Meta-analysis. ( Al Khalifah, RA; Bassilious, E; Dennis, B; Florez, ID; Thabane, L, 2016)
"Metformin was less effective than the OCP in improving menstrual pattern (Peto odds ratio (OR) 0."2.44Insulin-sensitising drugs versus the combined oral contraceptive pill for hirsutism, acne and risk of diabetes, cardiovascular disease, and endometrial cancer in polycystic ovary syndrome. ( Costello, M; Eden, J; Johnson, N; Shrestha, B; Sjoblom, P, 2007)
"Polycystic ovary syndrome is a multi-system endocrinopathy with long-term metabolic and cardiovascular health consequences."2.43Contemporary medical therapy for polycystic ovary syndrome. ( Domino, SE; Lanham, MS; Lebovic, DI, 2006)

Research

Studies (29)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's9 (31.03)29.6817
2010's11 (37.93)24.3611
2020's9 (31.03)2.80

Authors

AuthorsStudies
Albalat, W1
Darwish, H1
Abd-Elaal, WH1
AbouHadeed, MH1
Essam, R1
Raza, S1
Al-Niaimi, F1
Ali, FR1
Kamboj, P2
Kaushik, A1
Handa, S2
Dutta, P2
Saikia, UN1
Pal, A2
De, D2
Tseng, CH1
Sadati, MS1
Yazdanpanah, N1
Shahriarirad, R1
Javaheri, R1
Parvizi, MM1
Xiong, T1
Fraison, E1
Kolibianaki, E1
Costello, MF2
Venetis, C1
Kostova, EB1
Yen, H1
Chang, YT1
Yee, FJ1
Huang, YC1
Chang, JE1
Choi, MS1
Bishnoi, A1
Nahar Saikia, U1
Lepine, S1
Jo, J1
Metwally, M1
Cheong, YC1
Lee, JK1
Smith, AD1
Robinson, S1
Kwan, Z1
Tang, MM1
Roberts, TK1
Fantz, CR1
Buzney, E1
Sheu, J1
Buzney, C1
Reynolds, RV1
Fabbrocini, G1
Izzo, R1
Faggiano, A1
Del Prete, M1
Donnarumma, M1
Marasca, C1
Marciello, F1
Savastano, R1
Monfrecola, G1
Colao, A1
Al Khalifah, RA1
Florez, ID1
Dennis, B1
Thabane, L1
Bassilious, E1
Ding, T1
Baio, G1
Hardiman, PJ1
Petersen, I1
Sammon, C1
Klein, F1
Langmár, Z1
Bergstrom, KG1
Petrányi, G1
Zaoura-Petrányi, M1
Kazerooni, T1
Dehghan-Kooshkghazi, M1
Harborne, L1
Fleming, R1
Lyall, H1
Sattar, N1
Norman, J1
Heymann, WR1
Ehrmann, DA1
Lanham, MS1
Lebovic, DI1
Domino, SE1
Costello, M1
Shrestha, B2
Eden, J2
Sjoblom, P2
Johnson, N1
Johnson, NP1
Homburg, R1

Clinical Trials (9)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Descriptive, Transversal Study of Evaluation of Cardiovascular Risks Factors and Prevalence of Metabolic Syndrome in the Different Phenotypes of Women With Polycystic Ovary Syndrome[NCT00784615]80 participants (Anticipated)Observational2007-12-31Recruiting
Clinical Metabolic and Endocrine Parameters in Response to Metformin and Lifestyle Intervention in Women With Polycystic Ovary Syndrome: A Phase 4 Randomized, Double- Blind and Placebo Control Trial[NCT00679679]Phase 430 participants (Actual)Interventional2003-01-31Completed
Efficacy and Safety of Furocyst in Patients With Poly Cystic Ovary Syndrome[NCT02789488]Phase 450 participants (Actual)Interventional2013-09-30Completed
Anxiety and Sexual Malfunction in Infertile Polycystic Ovarian Syndrome Patients[NCT05056272]128 participants (Anticipated)Observational2022-01-01Recruiting
The Impact of Continuous Aerobic Exercise and High-Intensity Interval Training on Reproductive Outcomes in Polycystic Ovary Syndrome: A Pilot Randomized Controlled Trial.[NCT03362918]60 participants (Actual)Interventional2018-01-01Completed
Adipose Tissue Angiogenesis in Polycystic Ovary Syndrome (PCOS)[NCT01745471]36 participants (Anticipated)Observational2012-12-06Active, not recruiting
The Effects of Contraceptive Pill and Hormonal Vaginal Ring on Hormonal, Inflammatory and Metabolic Parameters in Women of Reproductive Age With Polycystic Ovary Syndrome (PCOS).[NCT01588873]Phase 442 participants (Anticipated)Interventional2012-04-30Recruiting
Pilot Study on the Effects of Fasting Mimicking Diet (FMD) in Women With Polycystic[NCT05196568]100 participants (Anticipated)Interventional2021-07-01Active, not recruiting
Is the Co-administration of Metformine and CC as Compared to Placebo and CC Superior to Induce Ovulation in PCOS Patients With a Confirmed insulin-resistant-a Double Blind Randomized Clinical Trial[NCT02523898]Phase 2388 participants (Anticipated)Interventional2015-11-30Enrolling by invitation
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

13 reviews available for metformin and Acne

ArticleYear
A systematic review of the uses of metformin in dermatology.
    Clinical and experimental dermatology, 2023, Feb-02, Volume: 48, Issue:2

    Topics: Acne Vulgaris; Dermatology; Diabetes Mellitus, Type 2; Female; Humans; Hypoglycemic Agents; Metformi

2023
Statins for women with polycystic ovary syndrome not actively trying to conceive.
    The Cochrane database of systematic reviews, 2023, 07-18, Volume: 7

    Topics: Acne Vulgaris; Contraceptives, Oral; Female; Hirsutism; Humans; Hydroxymethylglutaryl-CoA Reductase

2023
Metformin Therapy for Acne in Patients with Polycystic Ovary Syndrome: A Systematic Review and Meta-analysis.
    American journal of clinical dermatology, 2021, Volume: 22, Issue:1

    Topics: Acne Vulgaris; Androgen Antagonists; Drug Therapy, Combination; Female; Humans; Metformin; Non-Rando

2021
A Molecular Perspective on the Potential Benefits of Metformin for the Treatment of Inflammatory Skin Disorders.
    International journal of molecular sciences, 2020, Nov-25, Volume: 21, Issue:23

    Topics: Acanthosis Nigricans; Acne Vulgaris; Dermatitis, Allergic Contact; Hidradenitis Suppurativa; Humans;

2020
Ovarian surgery for symptom relief in women with polycystic ovary syndrome.
    The Cochrane database of systematic reviews, 2017, 11-10, Volume: 11

    Topics: Acne Vulgaris; Clomiphene; Female; Gonadotropins; Hirsutism; Humans; Laparoscopy; Letrozole; Menstru

2017
Metformin as an adjunct therapy for the treatment of moderate to severe acne vulgaris.
    Dermatology online journal, 2017, Nov-15, Volume: 23, Issue:11

    Topics: Acne Vulgaris; Adapalene; Anti-Bacterial Agents; Benzoyl Peroxide; Combined Modality Therapy; Dermat

2017
Polycystic ovary syndrome: a review for dermatologists: Part II. Treatment.
    Journal of the American Academy of Dermatology, 2014, Volume: 71, Issue:5

    Topics: 5-alpha Reductase Inhibitors; Acne Vulgaris; Alopecia; Androgen Antagonists; Contraceptives, Oral, C

2014
Metformin or Oral Contraceptives for Adolescents With Polycystic Ovarian Syndrome: A Meta-analysis.
    Pediatrics, 2016, Volume: 137, Issue:5

    Topics: Acne Vulgaris; Adolescent; Body Mass Index; Contraceptives, Oral; Female; Glucose Metabolism Disorde

2016
Polycystic ovary syndrome.
    The New England journal of medicine, 2005, Mar-24, Volume: 352, Issue:12

    Topics: Acne Vulgaris; Androgen Antagonists; Cardiovascular Diseases; Chromans; Contraceptives, Oral; Diabet

2005
Polycystic ovary syndrome.
    The New England journal of medicine, 2005, Mar-24, Volume: 352, Issue:12

    Topics: Acne Vulgaris; Androgen Antagonists; Cardiovascular Diseases; Chromans; Contraceptives, Oral; Diabet

2005
Polycystic ovary syndrome.
    The New England journal of medicine, 2005, Mar-24, Volume: 352, Issue:12

    Topics: Acne Vulgaris; Androgen Antagonists; Cardiovascular Diseases; Chromans; Contraceptives, Oral; Diabet

2005
Polycystic ovary syndrome.
    The New England journal of medicine, 2005, Mar-24, Volume: 352, Issue:12

    Topics: Acne Vulgaris; Androgen Antagonists; Cardiovascular Diseases; Chromans; Contraceptives, Oral; Diabet

2005
Polycystic ovary syndrome.
    The New England journal of medicine, 2005, Mar-24, Volume: 352, Issue:12

    Topics: Acne Vulgaris; Androgen Antagonists; Cardiovascular Diseases; Chromans; Contraceptives, Oral; Diabet

2005
Polycystic ovary syndrome.
    The New England journal of medicine, 2005, Mar-24, Volume: 352, Issue:12

    Topics: Acne Vulgaris; Androgen Antagonists; Cardiovascular Diseases; Chromans; Contraceptives, Oral; Diabet

2005
Polycystic ovary syndrome.
    The New England journal of medicine, 2005, Mar-24, Volume: 352, Issue:12

    Topics: Acne Vulgaris; Androgen Antagonists; Cardiovascular Diseases; Chromans; Contraceptives, Oral; Diabet

2005
Polycystic ovary syndrome.
    The New England journal of medicine, 2005, Mar-24, Volume: 352, Issue:12

    Topics: Acne Vulgaris; Androgen Antagonists; Cardiovascular Diseases; Chromans; Contraceptives, Oral; Diabet

2005
Polycystic ovary syndrome.
    The New England journal of medicine, 2005, Mar-24, Volume: 352, Issue:12

    Topics: Acne Vulgaris; Androgen Antagonists; Cardiovascular Diseases; Chromans; Contraceptives, Oral; Diabet

2005
Polycystic ovary syndrome.
    The New England journal of medicine, 2005, Mar-24, Volume: 352, Issue:12

    Topics: Acne Vulgaris; Androgen Antagonists; Cardiovascular Diseases; Chromans; Contraceptives, Oral; Diabet

2005
Polycystic ovary syndrome.
    The New England journal of medicine, 2005, Mar-24, Volume: 352, Issue:12

    Topics: Acne Vulgaris; Androgen Antagonists; Cardiovascular Diseases; Chromans; Contraceptives, Oral; Diabet

2005
Polycystic ovary syndrome.
    The New England journal of medicine, 2005, Mar-24, Volume: 352, Issue:12

    Topics: Acne Vulgaris; Androgen Antagonists; Cardiovascular Diseases; Chromans; Contraceptives, Oral; Diabet

2005
Polycystic ovary syndrome.
    The New England journal of medicine, 2005, Mar-24, Volume: 352, Issue:12

    Topics: Acne Vulgaris; Androgen Antagonists; Cardiovascular Diseases; Chromans; Contraceptives, Oral; Diabet

2005
Polycystic ovary syndrome.
    The New England journal of medicine, 2005, Mar-24, Volume: 352, Issue:12

    Topics: Acne Vulgaris; Androgen Antagonists; Cardiovascular Diseases; Chromans; Contraceptives, Oral; Diabet

2005
Polycystic ovary syndrome.
    The New England journal of medicine, 2005, Mar-24, Volume: 352, Issue:12

    Topics: Acne Vulgaris; Androgen Antagonists; Cardiovascular Diseases; Chromans; Contraceptives, Oral; Diabet

2005
Polycystic ovary syndrome.
    The New England journal of medicine, 2005, Mar-24, Volume: 352, Issue:12

    Topics: Acne Vulgaris; Androgen Antagonists; Cardiovascular Diseases; Chromans; Contraceptives, Oral; Diabet

2005
Polycystic ovary syndrome.
    The New England journal of medicine, 2005, Mar-24, Volume: 352, Issue:12

    Topics: Acne Vulgaris; Androgen Antagonists; Cardiovascular Diseases; Chromans; Contraceptives, Oral; Diabet

2005
Polycystic ovary syndrome.
    The New England journal of medicine, 2005, Mar-24, Volume: 352, Issue:12

    Topics: Acne Vulgaris; Androgen Antagonists; Cardiovascular Diseases; Chromans; Contraceptives, Oral; Diabet

2005
Polycystic ovary syndrome.
    The New England journal of medicine, 2005, Mar-24, Volume: 352, Issue:12

    Topics: Acne Vulgaris; Androgen Antagonists; Cardiovascular Diseases; Chromans; Contraceptives, Oral; Diabet

2005
Polycystic ovary syndrome.
    The New England journal of medicine, 2005, Mar-24, Volume: 352, Issue:12

    Topics: Acne Vulgaris; Androgen Antagonists; Cardiovascular Diseases; Chromans; Contraceptives, Oral; Diabet

2005
Polycystic ovary syndrome.
    The New England journal of medicine, 2005, Mar-24, Volume: 352, Issue:12

    Topics: Acne Vulgaris; Androgen Antagonists; Cardiovascular Diseases; Chromans; Contraceptives, Oral; Diabet

2005
Polycystic ovary syndrome.
    The New England journal of medicine, 2005, Mar-24, Volume: 352, Issue:12

    Topics: Acne Vulgaris; Androgen Antagonists; Cardiovascular Diseases; Chromans; Contraceptives, Oral; Diabet

2005
Polycystic ovary syndrome.
    The New England journal of medicine, 2005, Mar-24, Volume: 352, Issue:12

    Topics: Acne Vulgaris; Androgen Antagonists; Cardiovascular Diseases; Chromans; Contraceptives, Oral; Diabet

2005
Polycystic ovary syndrome.
    The New England journal of medicine, 2005, Mar-24, Volume: 352, Issue:12

    Topics: Acne Vulgaris; Androgen Antagonists; Cardiovascular Diseases; Chromans; Contraceptives, Oral; Diabet

2005
Polycystic ovary syndrome.
    The New England journal of medicine, 2005, Mar-24, Volume: 352, Issue:12

    Topics: Acne Vulgaris; Androgen Antagonists; Cardiovascular Diseases; Chromans; Contraceptives, Oral; Diabet

2005
Polycystic ovary syndrome.
    The New England journal of medicine, 2005, Mar-24, Volume: 352, Issue:12

    Topics: Acne Vulgaris; Androgen Antagonists; Cardiovascular Diseases; Chromans; Contraceptives, Oral; Diabet

2005
Polycystic ovary syndrome.
    The New England journal of medicine, 2005, Mar-24, Volume: 352, Issue:12

    Topics: Acne Vulgaris; Androgen Antagonists; Cardiovascular Diseases; Chromans; Contraceptives, Oral; Diabet

2005
Polycystic ovary syndrome.
    The New England journal of medicine, 2005, Mar-24, Volume: 352, Issue:12

    Topics: Acne Vulgaris; Androgen Antagonists; Cardiovascular Diseases; Chromans; Contraceptives, Oral; Diabet

2005
Polycystic ovary syndrome.
    The New England journal of medicine, 2005, Mar-24, Volume: 352, Issue:12

    Topics: Acne Vulgaris; Androgen Antagonists; Cardiovascular Diseases; Chromans; Contraceptives, Oral; Diabet

2005
Polycystic ovary syndrome.
    The New England journal of medicine, 2005, Mar-24, Volume: 352, Issue:12

    Topics: Acne Vulgaris; Androgen Antagonists; Cardiovascular Diseases; Chromans; Contraceptives, Oral; Diabet

2005
Polycystic ovary syndrome.
    The New England journal of medicine, 2005, Mar-24, Volume: 352, Issue:12

    Topics: Acne Vulgaris; Androgen Antagonists; Cardiovascular Diseases; Chromans; Contraceptives, Oral; Diabet

2005
Polycystic ovary syndrome.
    The New England journal of medicine, 2005, Mar-24, Volume: 352, Issue:12

    Topics: Acne Vulgaris; Androgen Antagonists; Cardiovascular Diseases; Chromans; Contraceptives, Oral; Diabet

2005
Polycystic ovary syndrome.
    The New England journal of medicine, 2005, Mar-24, Volume: 352, Issue:12

    Topics: Acne Vulgaris; Androgen Antagonists; Cardiovascular Diseases; Chromans; Contraceptives, Oral; Diabet

2005
Polycystic ovary syndrome.
    The New England journal of medicine, 2005, Mar-24, Volume: 352, Issue:12

    Topics: Acne Vulgaris; Androgen Antagonists; Cardiovascular Diseases; Chromans; Contraceptives, Oral; Diabet

2005
Polycystic ovary syndrome.
    The New England journal of medicine, 2005, Mar-24, Volume: 352, Issue:12

    Topics: Acne Vulgaris; Androgen Antagonists; Cardiovascular Diseases; Chromans; Contraceptives, Oral; Diabet

2005
Polycystic ovary syndrome.
    The New England journal of medicine, 2005, Mar-24, Volume: 352, Issue:12

    Topics: Acne Vulgaris; Androgen Antagonists; Cardiovascular Diseases; Chromans; Contraceptives, Oral; Diabet

2005
Polycystic ovary syndrome.
    The New England journal of medicine, 2005, Mar-24, Volume: 352, Issue:12

    Topics: Acne Vulgaris; Androgen Antagonists; Cardiovascular Diseases; Chromans; Contraceptives, Oral; Diabet

2005
Polycystic ovary syndrome.
    The New England journal of medicine, 2005, Mar-24, Volume: 352, Issue:12

    Topics: Acne Vulgaris; Androgen Antagonists; Cardiovascular Diseases; Chromans; Contraceptives, Oral; Diabet

2005
Polycystic ovary syndrome.
    The New England journal of medicine, 2005, Mar-24, Volume: 352, Issue:12

    Topics: Acne Vulgaris; Androgen Antagonists; Cardiovascular Diseases; Chromans; Contraceptives, Oral; Diabet

2005
Polycystic ovary syndrome.
    The New England journal of medicine, 2005, Mar-24, Volume: 352, Issue:12

    Topics: Acne Vulgaris; Androgen Antagonists; Cardiovascular Diseases; Chromans; Contraceptives, Oral; Diabet

2005
Polycystic ovary syndrome.
    The New England journal of medicine, 2005, Mar-24, Volume: 352, Issue:12

    Topics: Acne Vulgaris; Androgen Antagonists; Cardiovascular Diseases; Chromans; Contraceptives, Oral; Diabet

2005
Polycystic ovary syndrome.
    The New England journal of medicine, 2005, Mar-24, Volume: 352, Issue:12

    Topics: Acne Vulgaris; Androgen Antagonists; Cardiovascular Diseases; Chromans; Contraceptives, Oral; Diabet

2005
Polycystic ovary syndrome.
    The New England journal of medicine, 2005, Mar-24, Volume: 352, Issue:12

    Topics: Acne Vulgaris; Androgen Antagonists; Cardiovascular Diseases; Chromans; Contraceptives, Oral; Diabet

2005
Polycystic ovary syndrome.
    The New England journal of medicine, 2005, Mar-24, Volume: 352, Issue:12

    Topics: Acne Vulgaris; Androgen Antagonists; Cardiovascular Diseases; Chromans; Contraceptives, Oral; Diabet

2005
Polycystic ovary syndrome.
    The New England journal of medicine, 2005, Mar-24, Volume: 352, Issue:12

    Topics: Acne Vulgaris; Androgen Antagonists; Cardiovascular Diseases; Chromans; Contraceptives, Oral; Diabet

2005
Polycystic ovary syndrome.
    The New England journal of medicine, 2005, Mar-24, Volume: 352, Issue:12

    Topics: Acne Vulgaris; Androgen Antagonists; Cardiovascular Diseases; Chromans; Contraceptives, Oral; Diabet

2005
Polycystic ovary syndrome.
    The New England journal of medicine, 2005, Mar-24, Volume: 352, Issue:12

    Topics: Acne Vulgaris; Androgen Antagonists; Cardiovascular Diseases; Chromans; Contraceptives, Oral; Diabet

2005
Polycystic ovary syndrome.
    The New England journal of medicine, 2005, Mar-24, Volume: 352, Issue:12

    Topics: Acne Vulgaris; Androgen Antagonists; Cardiovascular Diseases; Chromans; Contraceptives, Oral; Diabet

2005
Polycystic ovary syndrome.
    The New England journal of medicine, 2005, Mar-24, Volume: 352, Issue:12

    Topics: Acne Vulgaris; Androgen Antagonists; Cardiovascular Diseases; Chromans; Contraceptives, Oral; Diabet

2005
Contemporary medical therapy for polycystic ovary syndrome.
    International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics, 2006, Volume: 95, Issue:3

    Topics: Acne Vulgaris; Adult; Clomiphene; Estrogen Antagonists; Female; Hirsutism; Humans; Hypoglycemic Agen

2006
Insulin-sensitising drugs versus the combined oral contraceptive pill for hirsutism, acne and risk of diabetes, cardiovascular disease, and endometrial cancer in polycystic ovary syndrome.
    The Cochrane database of systematic reviews, 2007, Jan-24, Issue:1

    Topics: Acne Vulgaris; Cardiovascular Diseases; Contraceptives, Oral, Combined; Endometrial Neoplasms; Femal

2007
Metformin versus oral contraceptive pill in polycystic ovary syndrome: a Cochrane review.
    Human reproduction (Oxford, England), 2007, Volume: 22, Issue:5

    Topics: Acne Vulgaris; Adult; Cardiovascular Diseases; Contraceptives, Oral, Combined; Female; Hirsutism; Hu

2007
Polycystic ovary syndrome.
    Best practice & research. Clinical obstetrics & gynaecology, 2008, Volume: 22, Issue:2

    Topics: Acne Vulgaris; Androgen Antagonists; Aromatase Inhibitors; Clomiphene; Female; Fertility Agents, Fem

2008

Trials

5 trials available for metformin and Acne

ArticleYear
Efficacy of metformin vs. doxycycline in treating acne vulgaris: An assessor-blinded, add-on, randomized, controlled clinical trial.
    Journal of cosmetic dermatology, 2023, Volume: 22, Issue:10

    Topics: Acne Vulgaris; Double-Blind Method; Doxycycline; Gels; Humans; Immunoglobulin A; Insulin-Like Growth

2023
Metformin as an adjunct therapy for the treatment of moderate to severe acne vulgaris: A randomized open-labeled study.
    Dermatologic therapy, 2019, Volume: 32, Issue:4

    Topics: Acne Vulgaris; Adolescent; Adult; Benzoyl Peroxide; Dermatologic Agents; Drug Therapy, Combination;

2019
Low glycaemic diet and metformin therapy: a new approach in male subjects with acne resistant to common treatments.
    Clinical and experimental dermatology, 2016, Volume: 41, Issue:1

    Topics: Acne Vulgaris; Adolescent; Adult; Combined Modality Therapy; Diet, Reducing; Glucose; Glycemic Index

2016
Effects of metformin therapy on hyperandrogenism in women with polycystic ovarian syndrome.
    Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology, 2003, Volume: 17, Issue:1

    Topics: Acne Vulgaris; Adolescent; Adult; Blood Glucose; Body Mass Index; Dehydroepiandrosterone Sulfate; Fa

2003
Metformin or antiandrogen in the treatment of hirsutism in polycystic ovary syndrome.
    The Journal of clinical endocrinology and metabolism, 2003, Volume: 88, Issue:9

    Topics: Acne Vulgaris; Androgen Antagonists; Anthropometry; Blood Glucose; Blood Pressure; Body Mass Index;

2003

Other Studies

11 other studies available for metformin and Acne

ArticleYear
The potential role of insulin-like growth factor 1 in acne vulgaris and its correlation with the clinical response before and after treatment with metformin.
    Journal of cosmetic dermatology, 2022, Volume: 21, Issue:11

    Topics: Acne Vulgaris; Adolescent; Adult; Humans; Insulin-Like Growth Factor I; Metformin; Young Adult

2022
Effects of metformin on clinical, hormonal and relevant gene expression parameters in patients with acne: an observational study.
    Clinical and experimental dermatology, 2023, Jun-05, Volume: 48, Issue:6

    Topics: Acne Vulgaris; Female; Gene Expression; Humans; Hypoglycemic Agents; Insulin; Insulin Resistance; In

2023
Differential Effects of Metformin on Immune-Mediated and Androgen-Mediated Non-Cancer Skin Diseases in Diabetes Patients: A Retrospective Cohort Study.
    Dermatology (Basel, Switzerland), 2023, Volume: 239, Issue:4

    Topics: Acne Vulgaris; Androgens; Diabetes Mellitus, Type 2; Hidradenitis Suppurativa; Humans; Metformin; Re

2023
Effects of metformin on experimentally induced acne on rabbit ear.
    Experimental dermatology, 2021, Volume: 30, Issue:7

    Topics: Acne Vulgaris; Animals; Disease Models, Animal; Metformin; Outcome Assessment, Health Care; Rabbits

2021
Easy bruising in a patient with secondary amenorrhea.
    Clinical chemistry, 2014, Volume: 60, Issue:8

    Topics: Acne Vulgaris; Adult; Amenorrhea; Contusions; Female; Hormones; Humans; Metformin; Polycystic Ovary

2014
Diagnosis and management of polycystic ovary syndrome in the UK (2004-2014): a retrospective cohort study.
    BMJ open, 2016, 07-11, Volume: 6, Issue:7

    Topics: Acne Vulgaris; Adolescent; Adult; Contraceptives, Oral, Combined; Drug Prescriptions; Female; Humans

2016
[Polycystic ovary syndrome. Diet helps control hormone chaos].
    MMW Fortschritte der Medizin, 2009, Sep-10, Volume: 151, Issue:37

    Topics: Acne Vulgaris; Adolescent; Adult; Androgens; Child; Combined Modality Therapy; Female; Hirsutism; Hu

2009
[Diagnosis and treatment of polycystic ovary syndrome].
    Orvosi hetilap, 2010, Apr-04, Volume: 151, Issue:14

    Topics: Acne Vulgaris; Alopecia; Amenorrhea; Androgens; Clomiphene; Diabetes Complications; Diagnosis, Diffe

2010
Everything old is new again: spironolactone and metformin in the treatment of acne.
    Journal of drugs in dermatology : JDD, 2010, Volume: 9, Issue:5

    Topics: Acne Vulgaris; Clinical Trials as Topic; Dermatologic Agents; Humans; Hypoglycemic Agents; Metformin

2010
[Metformin treatment with or without life style changes in patients with polycystic ovary syndrome].
    Orvosi hetilap, 2011, Apr-17, Volume: 152, Issue:16

    Topics: Acne Vulgaris; Adult; Body Mass Index; Caloric Restriction; Case-Control Studies; Drug Administratio

2011
Hyperandrogenism and the skin.
    Journal of the American Academy of Dermatology, 2004, Volume: 50, Issue:6

    Topics: Acne Vulgaris; Adrenal Hyperplasia, Congenital; Female; Humans; Hyperandrogenism; Male; Metformin; P

2004